4NBPA

Crystal structure of the jcv large t-antigen origin binding domain
Total Genus 35
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
35
sequence length
129
structure length
129
Chain Sequence
VEDPKDFPVDLHAFLSQAVFSNRTVASFAVYTTKEKAQILYKKLMEKYSVTFISRHGFGGHNILFFLTPHRHRVSAINNYCQKLCTFSFLICKGVNKEYLFYSALCRQPYAVVEESIQGGLKEHDFNPE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Insights into the Initiation of JC Virus DNA Replication Derived from the Crystal Structure of the T-Antigen Origin Binding Domain.
pubmed doi rcsb
molecule tags Hydrolase
source organism Jc polyomavirus
molecule keywords Large T antigen
total genus 35
structure length 129
sequence length 129
ec nomenclature ec 3.6.4.-:
pdb deposition date 2013-10-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02217 T_Ag_DNA_bind Origin of replication binding protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1310.20 Alpha Beta 3-Layer(aba) Sandwich Replication Protein E1; Chain: A, Replication Protein E1; Chain: A, 4nbpA00
1RZ9A 2NTCA 5D9IA 2NL8A 1TBDA 4FB3A 1Z1DB 5CYNA 2ITJA 1UUTA 4GDFA 1L5IA 4NBPA 2HW0A 2FUFA 1L2MA 4ZQ9A 4ZO0A 3QN2A 4LMDA 3QFQA 2IPRA 2TBDA 5DCXA 2ITLA 4FGNA 2IF9A 3QK2A 5BYGA 1M55A 4LIFA
chains in the Genus database with same CATH superfamily
1RZ9A 2NTCA 5D9IA 2NL8A 1TBDA 4FB3A 1Z1DB 5CYNA 4U87A 2ITJA 1UUTA 4GDFA 1KSXA 1L5IA 4NBPA 2HW0A 3DKYA 2FUFA 1L2MA 4KW3A 4ZQ9A 4ZO0A 3QN2A 4LMDA 3QFQA 2IPRA 2TBDA 3DKXA 5DCXA 1KSYA 2ITLA 4FGNA 3QK2A 2IF9A 1R9WA 5BYGA 1F08A 1M55A 4LIFA
chains in the Genus database with same CATH topology
1RZ9A 2NTCA 5D9IA 2NL8A 1TBDA 4FB3A 1Z1DB 5CYNA 4U87A 2ITJA 1UUTA 4GDFA 1KSXA 1L5IA 4NBPA 2HW0A 3DKYA 2FUFA 1L2MA 4KW3A 4ZQ9A 4ZO0A 3QN2A 4LMDA 3QFQA 2IPRA 2TBDA 3DKXA 5DCXA 1KSYA 2ITLA 4FGNA 3QK2A 2IF9A 1R9WA 5BYGA 1F08A 1M55A 4LIFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1RZ9 A;  2NTC A;  5D9I A;  2NL8 A;  1TBD A;  4FB3 A;  1Z1D B;  5CYN A;  2ITJ A;  1UUT A;  4GDF A;  1L5I A;  4NBP A;  2HW0 A;  2FUF A;  1L2M A;  4ZQ9 A;  4ZO0 A;  3QN2 A;  4LMD A;  3QFQ A;  2IPR A;  2TBD A;  5DCX A;  2ITL A;  4FGN A;  2IF9 A;  3QK2 A;  5BYG A;  1M55 A;  4LIF A; 
#chains in the Genus database with same CATH topology
 1RZ9 A;  2NTC A;  5D9I A;  2NL8 A;  1TBD A;  4FB3 A;  1Z1D B;  5CYN A;  4U87 A;  2ITJ A;  1UUT A;  4GDF A;  1KSX A;  1L5I A;  4NBP A;  2HW0 A;  3DKY A;  2FUF A;  1L2M A;  4KW3 A;  4ZQ9 A;  4ZO0 A;  3QN2 A;  4LMD A;  3QFQ A;  2IPR A;  2TBD A;  3DKX A;  5DCX A;  1KSY A;  2ITL A;  4FGN A;  3QK2 A;  2IF9 A;  1R9W A;  5BYG A;  1F08 A;  1M55 A;  4LIF A; 
#chains in the Genus database with same CATH homology
 1RZ9 A;  2NTC A;  5D9I A;  2NL8 A;  1TBD A;  4FB3 A;  1Z1D B;  5CYN A;  4U87 A;  2ITJ A;  1UUT A;  4GDF A;  1KSX A;  1L5I A;  4NBP A;  2HW0 A;  3DKY A;  2FUF A;  1L2M A;  4KW3 A;  4ZQ9 A;  4ZO0 A;  3QN2 A;  4LMD A;  3QFQ A;  2IPR A;  2TBD A;  3DKX A;  5DCX A;  1KSY A;  2ITL A;  4FGN A;  3QK2 A;  2IF9 A;  1R9W A;  5BYG A;  1F08 A;  1M55 A;  4LIF A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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