4NBPA

Crystal structure of the jcv large t-antigen origin binding domain
Total Genus 35
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
35
sequence length
129
structure length
129
Chain Sequence
VEDPKDFPVDLHAFLSQAVFSNRTVASFAVYTTKEKAQILYKKLMEKYSVTFISRHGFGGHNILFFLTPHRHRVSAINNYCQKLCTFSFLICKGVNKEYLFYSALCRQPYAVVEESIQGGLKEHDFNPE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Hydrolase
source organism Jc polyomavirus
publication title Insights into the Initiation of JC Virus DNA Replication Derived from the Crystal Structure of the T-Antigen Origin Binding Domain.
pubmed doi rcsb
molecule keywords Large T antigen
total genus 35
structure length 129
sequence length 129
ec nomenclature ec 3.6.4.-:
pdb deposition date 2013-10-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02217 T_Ag_DNA_bind Origin of replication binding protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1310.20 Alpha Beta 3-Layer(aba) Sandwich Replication Protein E1; Chain: A, Replication Protein E1; Chain: A, 4nbpA00
3QFQA 2IF9A 1L2MA 1Z1DB 2NTCA 4ZQ9A 4NBPA 3QN2A 4LIFA 2TBDA 2FUFA 2NL8A 1RZ9A 5BYGA 1UUTA 5CYNA 2ITJA 2HW0A 5DCXA 5D9IA 4FGNA 4ZO0A 1TBDA 2IPRA 4FB3A 1L5IA 2ITLA 1M55A 3QK2A 4LMDA 4GDFA
chains in the Genus database with same CATH superfamily
3QFQA 2IF9A 1L2MA 3DKXA 1Z1DB 2NTCA 1KSXA 3DKYA 4ZQ9A 4NBPA 3QN2A 4LIFA 2TBDA 2FUFA 2NL8A 1RZ9A 1KSYA 5BYGA 1UUTA 1R9WA 5CYNA 2ITJA 4KW3A 2HW0A 5DCXA 5D9IA 4FGNA 4U87A 4ZO0A 1TBDA 2IPRA 4FB3A 1L5IA 2ITLA 1M55A 1F08A 3QK2A 4LMDA 4GDFA
chains in the Genus database with same CATH topology
3QFQA 2IF9A 1L2MA 3DKXA 1Z1DB 2NTCA 1KSXA 3DKYA 4ZQ9A 4NBPA 3QN2A 4LIFA 2TBDA 2FUFA 2NL8A 1RZ9A 1KSYA 5BYGA 1UUTA 1R9WA 5CYNA 2ITJA 4KW3A 2HW0A 5DCXA 5D9IA 4FGNA 4U87A 4ZO0A 1TBDA 2IPRA 4FB3A 1L5IA 2ITLA 1M55A 1F08A 3QK2A 4LMDA 4GDFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3QFQ A;  2IF9 A;  1L2M A;  1Z1D B;  2NTC A;  4ZQ9 A;  4NBP A;  3QN2 A;  4LIF A;  2TBD A;  2FUF A;  2NL8 A;  1RZ9 A;  5BYG A;  1UUT A;  5CYN A;  2ITJ A;  2HW0 A;  5DCX A;  5D9I A;  4FGN A;  4ZO0 A;  1TBD A;  2IPR A;  4FB3 A;  1L5I A;  2ITL A;  1M55 A;  3QK2 A;  4LMD A;  4GDF A; 
#chains in the Genus database with same CATH topology
 3QFQ A;  2IF9 A;  1L2M A;  3DKX A;  1Z1D B;  2NTC A;  1KSX A;  3DKY A;  4ZQ9 A;  4NBP A;  3QN2 A;  4LIF A;  2TBD A;  2FUF A;  2NL8 A;  1RZ9 A;  1KSY A;  5BYG A;  1UUT A;  1R9W A;  5CYN A;  2ITJ A;  4KW3 A;  2HW0 A;  5DCX A;  5D9I A;  4FGN A;  4U87 A;  4ZO0 A;  1TBD A;  2IPR A;  4FB3 A;  1L5I A;  2ITL A;  1M55 A;  1F08 A;  3QK2 A;  4LMD A;  4GDF A; 
#chains in the Genus database with same CATH homology
 3QFQ A;  2IF9 A;  1L2M A;  3DKX A;  1Z1D B;  2NTC A;  1KSX A;  3DKY A;  4ZQ9 A;  4NBP A;  3QN2 A;  4LIF A;  2TBD A;  2FUF A;  2NL8 A;  1RZ9 A;  1KSY A;  5BYG A;  1UUT A;  1R9W A;  5CYN A;  2ITJ A;  4KW3 A;  2HW0 A;  5DCX A;  5D9I A;  4FGN A;  4U87 A;  4ZO0 A;  1TBD A;  2IPR A;  4FB3 A;  1L5I A;  2ITL A;  1M55 A;  1F08 A;  3QK2 A;  4LMD A;  4GDF A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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