4NTWB

Structure of acid-sensing ion channel in complex with snake toxin
Total Genus 14
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
14
sequence length
60
structure length
60
Chain Sequence
EIRPAFCYEDPPFFQKCGAFVDSYYFNRSRITCVHFFYGQCDVNQNHFTTMSECNRVCHG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title X-ray structure of Acid-sensing ion channel 1-snake toxin complex reveals open state of a na(+)-selective channel.
pubmed doi rcsb
molecule tags Transport protein/toxin
source organism Gallus gallus
molecule keywords Acid-sensing ion channel 1
total genus 14
structure length 60
sequence length 60
ec nomenclature
pdb deposition date 2013-12-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00014 Kunitz_BPTI Kunitz/Bovine pancreatic trypsin inhibitor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.410.10 Few Secondary Structures Irregular Factor Xa Inhibitor Pancreatic trypsin inhibitor Kunitz domain 4ntwB00
9PTIA 1T8MB 1BTIA 1P2KI 2UUXA 4NTXB 5JB4A 3OTJI 1F7ZI 4BD9B 1BIKA 1CA0D 1F5RI 1KIGI 1B0CA 2RA3C 1BPTA 4Y0ZI 3L3TE 1JC6A 1TCPA 1YC0I 4BNRI 1ADZA 3P92E 1CBWD 3M7QB 1T8NB 1UUAA 2CA7A 1YKTB 1DTKA 1P2JI 4ISLB 1TAPA 1AALA 3BTMI 1BRCI 1BZ5A 3T62D 8PTIA 1LD6A 3BTQI 1ZR0B 4WWYC 3CI7A 1YLCB 1Y62A 4NTWB 3BTDI 3BYBA 5JB5A 1ZJDB 3TGKI 1FAKI 1DTXA 3BTWI 1G6XA 1AAPA 3BTTI 3LDJA 4U32X 1BTHP 2TPII 1EAWB 1TAWB 4Y10I 1BUNB 3D65I 3AUHA 3BTFI 4DTGK 1DEMA 3TGJI 1OA65 3OFWA 1QLQA 2HEXA 1PITA 3U1JE 2J6DA 1JV9A 1BRBI 4NTYB 4ISNB 1P2NB 3UOUB 2FTLI 1IRHA 2FTMB 1CO7I 1P2OB 1KTHA 2W8XA 1BF0A 2ZJXA 1D0DB 3BTKI 5JB7A 1TFXC 4WXVC 1DENA 1UUBA 1T8LB 1FY8I 3FP7J 4U30W 1KUNA 1LD5A 4Y0YI 1KNTA 1P2II 3BTGI 1TPAI 1P2MB 3AUCA 6PTIA 2R9PE 3L33E 2KCRA 2M99A 5C67C 1JV8A 3UIRC 1TOCR 1OA55 3FP8I 2LFKA 1BHCA 5JB6A 4TPII 2IJOI 1FANA 4DG4C 3AUBA 3P95E 1T8OB 1YLDB 2DDIA 2ODYE 4BQDA 1NAGA 2DDJA 2KAII 1P2QB 2M01A 3AUGA 3BTEI 3LDIA 3AUIA 1T7CB 1SHPA 3AUDA 1D0DA 3FP6I 2JOTA 4ISOB 2PTCI 2LFLA 3TGII 3AUEA 2KNTA 1BPIA 1BZXI 2TGPI 2FI3I 3LDMA 7PTIA 1EJMB 2ZVXA 3BTHI 4PTIA 3GYMI 3WNYA 2FI5I 5PTIA 1K6UA 2UUYB 4Y11I 3TPII 1MTND 2FI4I
chains in the Genus database with same CATH superfamily
9PTIA 1T8MB 1BTIA 1P2KI 2UUXA 4NTXB 5JB4A 3OTJI 1F7ZI 4BD9B 1BIKA 1CA0D 1F5RI 1KIGI 1B0CA 2RA3C 1BPTA 4Y0ZI 3L3TE 1JC6A 1TCPA 1YC0I 4BNRI 1ADZA 3P92E 1CBWD 3M7QB 1T8NB 1UUAA 2CA7A 1YKTB 1DTKA 1P2JI 4ISLB 1TAPA 1AALA 3BTMI 1BRCI 1BZ5A 3T62D 8PTIA 1LD6A 3BTQI 1ZR0B 4WWYC 3CI7A 1YLCB 1Y62A 4NTWB 3BTDI 3BYBA 5JB5A 1ZJDB 3TGKI 1FAKI 1DTXA 3BTWI 1G6XA 1AAPA 3BTTI 3LDJA 4U32X 1BTHP 2TPII 1EAWB 1TAWB 4Y10I 1BUNB 3D65I 3AUHA 3BTFI 4DTGK 1DEMA 3TGJI 1OA65 3OFWA 1QLQA 2HEXA 1PITA 3U1JE 2J6DA 1JV9A 1BRBI 4NTYB 4ISNB 1P2NB 3UOUB 2FTLI 1IRHA 2FTMB 1CO7I 1P2OB 1KTHA 2W8XA 1BF0A 2ZJXA 1D0DB 3BTKI 5JB7A 1TFXC 4WXVC 1DENA 1UUBA 1T8LB 1FY8I 3FP7J 4U30W 1KUNA 1LD5A 4Y0YI 1KNTA 1P2II 3BTGI 1TPAI 1P2MB 3AUCA 6PTIA 2R9PE 3L33E 2KCRA 2M99A 5C67C 1JV8A 3UIRC 1TOCR 1OA55 3FP8I 2LFKA 1BHCA 5JB6A 4TPII 2IJOI 1FANA 4DG4C 3AUBA 3P95E 1T8OB 1YLDB 2DDIA 2ODYE 4BQDA 1NAGA 2DDJA 2KAII 1P2QB 2M01A 3AUGA 3BTEI 3LDIA 3AUIA 1T7CB 1SHPA 3AUDA 1D0DA 3FP6I 2JOTA 4ISOB 2PTCI 2LFLA 3TGII 3AUEA 2KNTA 1BPIA 1BZXI 2TGPI 2FI3I 3LDMA 7PTIA 1EJMB 2ZVXA 3BTHI 4PTIA 3GYMI 3WNYA 2FI5I 5PTIA 1K6UA 2UUYB 4Y11I 3TPII 1MTND 2FI4I
chains in the Genus database with same CATH topology
9PTIA 1T8MB 1BTIA 1P2KI 2UUXA 4NTXB 5JB4A 3OTJI 1F7ZI 4BD9B 1BIKA 1CA0D 1F5RI 1KIGI 1B0CA 2RA3C 1BPTA 4Y0ZI 3L3TE 1JC6A 1TCPA 1YC0I 4BNRI 1ADZA 3P92E 1CBWD 3M7QB 1T8NB 1UUAA 2CA7A 1YKTB 1DTKA 1P2JI 4ISLB 1TAPA 1AALA 3BTMI 1BRCI 1BZ5A 3T62D 8PTIA 1LD6A 3BTQI 1ZR0B 4WWYC 3CI7A 1YLCB 1Y62A 4NTWB 3BTDI 3BYBA 5JB5A 1ZJDB 3TGKI 1FAKI 1DTXA 3BTWI 1G6XA 1AAPA 3BTTI 3LDJA 4U32X 1BTHP 2TPII 1EAWB 1TAWB 4Y10I 1BUNB 3D65I 3AUHA 3BTFI 4DTGK 1DEMA 3TGJI 1OA65 3OFWA 1QLQA 2HEXA 1PITA 3U1JE 2J6DA 1JV9A 1BRBI 4NTYB 4ISNB 1P2NB 3UOUB 2FTLI 1IRHA 2FTMB 1CO7I 1P2OB 1KTHA 2W8XA 1BF0A 2ZJXA 1D0DB 3BTKI 5JB7A 1TFXC 4WXVC 1DENA 1UUBA 1T8LB 1FY8I 3FP7J 4U30W 1KUNA 1LD5A 4Y0YI 1KNTA 1P2II 3BTGI 1TPAI 1P2MB 3AUCA 6PTIA 2R9PE 3L33E 2KCRA 2M99A 5C67C 1JV8A 3UIRC 1TOCR 1OA55 3FP8I 2LFKA 1BHCA 5JB6A 4TPII 2IJOI 1FANA 4DG4C 3AUBA 3P95E 1T8OB 1YLDB 2DDIA 2ODYE 4BQDA 1NAGA 2DDJA 2KAII 1P2QB 2M01A 3AUGA 3BTEI 3LDIA 3AUIA 1T7CB 1SHPA 3AUDA 1D0DA 3FP6I 2JOTA 4ISOB 2PTCI 2LFLA 3TGII 3AUEA 2KNTA 1BPIA 1BZXI 2TGPI 2FI3I 3LDMA 7PTIA 1EJMB 2ZVXA 3BTHI 4PTIA 3GYMI 3WNYA 2FI5I 5PTIA 1K6UA 2UUYB 4Y11I 3TPII 1MTND 2FI4I
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 9PTI A;  1T8M B;  1BTI A;  1P2K I;  2UUX A;  4NTX B;  5JB4 A;  3OTJ I;  1F7Z I;  4BD9 B;  1BIK A;  1CA0 D;  1F5R I;  1KIG I;  1B0C A;  2RA3 C;  1BPT A;  4Y0Z I;  3L3T E;  1JC6 A;  1TCP A;  1YC0 I;  4BNR I;  1ADZ A;  3P92 E;  1CBW D;  3M7Q B;  1T8N B;  1UUA A;  2CA7 A;  1YKT B;  1DTK A;  1P2J I;  4ISL B;  1TAP A;  1AAL A;  3BTM I;  1BRC I;  1BZ5 A;  3T62 D;  8PTI A;  1LD6 A;  3BTQ I;  1ZR0 B;  4WWY C;  3CI7 A;  1YLC B;  1Y62 A;  4NTW B;  3BTD I;  3BYB A;  5JB5 A;  1ZJD B;  3TGK I;  1FAK I;  1DTX A;  3BTW I;  1G6X A;  1AAP A;  3BTT I;  3LDJ A;  4U32 X;  1BTH P;  2TPI I;  1EAW B;  1TAW B;  4Y10 I;  1BUN B;  3D65 I;  3AUH A;  3BTF I;  4DTG K;  1DEM A;  3TGJ I;  1OA6 5;  3OFW A;  1QLQ A;  2HEX A;  1PIT A;  3U1J E;  2J6D A;  1JV9 A;  1BRB I;  4NTY B;  4ISN B;  1P2N B;  3UOU B;  2FTL I;  1IRH A;  2FTM B;  1CO7 I;  1P2O B;  1KTH A;  2W8X A;  1BF0 A;  2ZJX A;  1D0D B;  3BTK I;  5JB7 A;  1TFX C;  4WXV C;  1DEN A;  1UUB A;  1T8L B;  1FY8 I;  3FP7 J;  4U30 W;  1KUN A;  1LD5 A;  4Y0Y I;  1KNT A;  1P2I I;  3BTG I;  1TPA I;  1P2M B;  3AUC A;  6PTI A;  2R9P E;  3L33 E;  2KCR A;  2M99 A;  5C67 C;  1JV8 A;  3UIR C;  1TOC R;  1OA5 5;  3FP8 I;  2LFK A;  1BHC A;  5JB6 A;  4TPI I;  2IJO I;  1FAN A;  4DG4 C;  3AUB A;  3P95 E;  1T8O B;  1YLD B;  2DDI A;  2ODY E;  4BQD A;  1NAG A;  2DDJ A;  2KAI I;  1P2Q B;  2M01 A;  3AUG A;  3BTE I;  3LDI A;  3AUI A;  1T7C B;  1SHP A;  3AUD A;  1D0D A;  3FP6 I;  2JOT A;  4ISO B;  2PTC I;  2LFL A;  3TGI I;  3AUE A;  2KNT A;  1BPI A;  1BZX I;  2TGP I;  2FI3 I;  3LDM A;  7PTI A;  1EJM B;  2ZVX A;  3BTH I;  4PTI A;  3GYM I;  3WNY A;  2FI5 I;  5PTI A;  1K6U A;  2UUY B;  4Y11 I;  3TPI I;  1MTN D;  2FI4 I; 
#chains in the Genus database with same CATH topology
 9PTI A;  1T8M B;  1BTI A;  1P2K I;  2UUX A;  4NTX B;  5JB4 A;  3OTJ I;  1F7Z I;  4BD9 B;  1BIK A;  1CA0 D;  1F5R I;  1KIG I;  1B0C A;  2RA3 C;  1BPT A;  4Y0Z I;  3L3T E;  1JC6 A;  1TCP A;  1YC0 I;  4BNR I;  1ADZ A;  3P92 E;  1CBW D;  3M7Q B;  1T8N B;  1UUA A;  2CA7 A;  1YKT B;  1DTK A;  1P2J I;  4ISL B;  1TAP A;  1AAL A;  3BTM I;  1BRC I;  1BZ5 A;  3T62 D;  8PTI A;  1LD6 A;  3BTQ I;  1ZR0 B;  4WWY C;  3CI7 A;  1YLC B;  1Y62 A;  4NTW B;  3BTD I;  3BYB A;  5JB5 A;  1ZJD B;  3TGK I;  1FAK I;  1DTX A;  3BTW I;  1G6X A;  1AAP A;  3BTT I;  3LDJ A;  4U32 X;  1BTH P;  2TPI I;  1EAW B;  1TAW B;  4Y10 I;  1BUN B;  3D65 I;  3AUH A;  3BTF I;  4DTG K;  1DEM A;  3TGJ I;  1OA6 5;  3OFW A;  1QLQ A;  2HEX A;  1PIT A;  3U1J E;  2J6D A;  1JV9 A;  1BRB I;  4NTY B;  4ISN B;  1P2N B;  3UOU B;  2FTL I;  1IRH A;  2FTM B;  1CO7 I;  1P2O B;  1KTH A;  2W8X A;  1BF0 A;  2ZJX A;  1D0D B;  3BTK I;  5JB7 A;  1TFX C;  4WXV C;  1DEN A;  1UUB A;  1T8L B;  1FY8 I;  3FP7 J;  4U30 W;  1KUN A;  1LD5 A;  4Y0Y I;  1KNT A;  1P2I I;  3BTG I;  1TPA I;  1P2M B;  3AUC A;  6PTI A;  2R9P E;  3L33 E;  2KCR A;  2M99 A;  5C67 C;  1JV8 A;  3UIR C;  1TOC R;  1OA5 5;  3FP8 I;  2LFK A;  1BHC A;  5JB6 A;  4TPI I;  2IJO I;  1FAN A;  4DG4 C;  3AUB A;  3P95 E;  1T8O B;  1YLD B;  2DDI A;  2ODY E;  4BQD A;  1NAG A;  2DDJ A;  2KAI I;  1P2Q B;  2M01 A;  3AUG A;  3BTE I;  3LDI A;  3AUI A;  1T7C B;  1SHP A;  3AUD A;  1D0D A;  3FP6 I;  2JOT A;  4ISO B;  2PTC I;  2LFL A;  3TGI I;  3AUE A;  2KNT A;  1BPI A;  1BZX I;  2TGP I;  2FI3 I;  3LDM A;  7PTI A;  1EJM B;  2ZVX A;  3BTH I;  4PTI A;  3GYM I;  3WNY A;  2FI5 I;  5PTI A;  1K6U A;  2UUY B;  4Y11 I;  3TPI I;  1MTN D;  2FI4 I; 
#chains in the Genus database with same CATH homology
 9PTI A;  1T8M B;  1BTI A;  1P2K I;  2UUX A;  4NTX B;  5JB4 A;  3OTJ I;  1F7Z I;  4BD9 B;  1BIK A;  1CA0 D;  1F5R I;  1KIG I;  1B0C A;  2RA3 C;  1BPT A;  4Y0Z I;  3L3T E;  1JC6 A;  1TCP A;  1YC0 I;  4BNR I;  1ADZ A;  3P92 E;  1CBW D;  3M7Q B;  1T8N B;  1UUA A;  2CA7 A;  1YKT B;  1DTK A;  1P2J I;  4ISL B;  1TAP A;  1AAL A;  3BTM I;  1BRC I;  1BZ5 A;  3T62 D;  8PTI A;  1LD6 A;  3BTQ I;  1ZR0 B;  4WWY C;  3CI7 A;  1YLC B;  1Y62 A;  4NTW B;  3BTD I;  3BYB A;  5JB5 A;  1ZJD B;  3TGK I;  1FAK I;  1DTX A;  3BTW I;  1G6X A;  1AAP A;  3BTT I;  3LDJ A;  4U32 X;  1BTH P;  2TPI I;  1EAW B;  1TAW B;  4Y10 I;  1BUN B;  3D65 I;  3AUH A;  3BTF I;  4DTG K;  1DEM A;  3TGJ I;  1OA6 5;  3OFW A;  1QLQ A;  2HEX A;  1PIT A;  3U1J E;  2J6D A;  1JV9 A;  1BRB I;  4NTY B;  4ISN B;  1P2N B;  3UOU B;  2FTL I;  1IRH A;  2FTM B;  1CO7 I;  1P2O B;  1KTH A;  2W8X A;  1BF0 A;  2ZJX A;  1D0D B;  3BTK I;  5JB7 A;  1TFX C;  4WXV C;  1DEN A;  1UUB A;  1T8L B;  1FY8 I;  3FP7 J;  4U30 W;  1KUN A;  1LD5 A;  4Y0Y I;  1KNT A;  1P2I I;  3BTG I;  1TPA I;  1P2M B;  3AUC A;  6PTI A;  2R9P E;  3L33 E;  2KCR A;  2M99 A;  5C67 C;  1JV8 A;  3UIR C;  1TOC R;  1OA5 5;  3FP8 I;  2LFK A;  1BHC A;  5JB6 A;  4TPI I;  2IJO I;  1FAN A;  4DG4 C;  3AUB A;  3P95 E;  1T8O B;  1YLD B;  2DDI A;  2ODY E;  4BQD A;  1NAG A;  2DDJ A;  2KAI I;  1P2Q B;  2M01 A;  3AUG A;  3BTE I;  3LDI A;  3AUI A;  1T7C B;  1SHP A;  3AUD A;  1D0D A;  3FP6 I;  2JOT A;  4ISO B;  2PTC I;  2LFL A;  3TGI I;  3AUE A;  2KNT A;  1BPI A;  1BZX I;  2TGP I;  2FI3 I;  3LDM A;  7PTI A;  1EJM B;  2ZVX A;  3BTH I;  4PTI A;  3GYM I;  3WNY A;  2FI5 I;  5PTI A;  1K6U A;  2UUY B;  4Y11 I;  3TPI I;  1MTN D;  2FI4 I; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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