4X6AF

Crystal structure of yeast rna polymerase ii encountering oxidative cyclopurine dna lesions
Total Genus 17
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
17
sequence length
84
structure length
84
Chain Sequence
KAIPKDQRATTPYMTKYERARILGTRALQISMNAPVFVDLEGETDPLRIAMKELAEKKIPLVIRRYLPDGSFEDWSVEELIVDL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
molecule tags Transcription/dna
publication title Mechanism of RNA polymerase II bypass of oxidative cyclopurine DNA lesions.
pubmed doi rcsb
molecule keywords DNA-directed RNA polymerase II subunit RPB1
total genus 17
structure length 84
sequence length 84
ec nomenclature
pdb deposition date 2014-12-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
F PF01192 RNA_pol_Rpb6 RNA polymerase Rpb6
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.940.10 Alpha Beta Alpha-Beta Complex Eukaryotic RPB6 RNA polymerase subunit Eukaryotic RPB6 RNA polymerase subunit 4x6aF00
4A3BF 4A3IF 1SFOF 4BY1F 4XSXE 1IW7E 4G7OE 3S2HF 2R93F 2O5JE 1R9TF 3HOWF 2WAQK 1ZYRE 4ZH4E 1I3QF 5D4CE 3FKIF 4KN7E 2YU9F 3HOYF 2NVQF 3HOZF 4C3JF 4YFNE 2NVYF 2E2IF 5D4EE 2VUMF 2A6HE 1HQME 3S14F 3PO3F 4LLGE 3H3VG 4X6AF 2E2JF 5C3EF 5E17E 5M3MF 1Y1VF 1K83F 4C2MF 1QKLA 4OIRE 5IYCF 4YG2E 2NVXF 4A3CF 5IYDF 2A6EE 5D4DE 5M5WF 3M3YF 4XSZE 5M3FF 4XLNE 4Y7NF 2Y0SI 5C4JF 1I50F 1WCMF 1TWFF 2B63F 4LK1E 5IYBF 4AYBK 4A93F 4Q4ZE 3HOXF 4Y52F 3GTKF 5IP9F 1Y1WF 4BBSF 4A3JF 5M5YF 4MEXE 4MQ9E 2NVTF 2O5IE 4C3IF 3S1RF 4LK0E 3H0GF 2E2HF 5C4XF 4MEYE 3S17F 4LJZE 4Q5SE 2PPBE 1YNNK 2CW0E 1TWCF 4OIQE 4A3EF 5FJ8F 5TMFE 1I6HF 4JK1E 4A3FF 5IPLE 4A3DF 3HOVF 4XLPE 4G7HE 4BBRF 2WB1I 2A68E 3K7AF 3RZDF 2R92F 3S2DF 3S1NF 2JA8F 5M5XF 3S16F 4A3GF 3GTLF 3HOUF 3I4NF 4OIOE 3M4OF 5FLMF 3GTQF 5TMCE 3GTJF 3I4MF 3S1QF 1I6VE 5BYHE 3RZOF 2R7ZF 4GZYE 4KMUE 3S1MF 1TWGF 3PO2F 3HKZK 2JA5F 3GTOF 4YFXE 4YFKE 3EQLE 4KN4E 1TWAF 4OINE 3WODE 2A69E 4OIPE 5E18E 3GTMF 3CQZF 4G7ZE 2JA7F 4A3KF 4A3MF 4BY7F 1SMYE 2PMZK 1TWHF 5C44F 3S15F 3DXJE 2JA6F 3GTGF 1YNJK 4BXXF 5IP7F 2BE5E 4A3LF 4C3HF 3GTPF
chains in the Genus database with same CATH superfamily
3GTJE 4A3BF 4A3BE 4A3IF 4BBSF 1SFOF 3S1QE 4BY1F 4BBSE 2WAQH 3RZOE 4XSXE 1IW7E 4G7OE 1EIKA 3S1ME 3S2HF 3S2HE 3PO2E 2R93F 2O5JE 1R9TF 3HOWF 2WAQK 1ZYRE 4ZH4E 1TWAE 1I3QF 5D4CE 4KN7E 3FKIF 3FKIE 2YU9F 2JA7E 3HOYE 3HOYF 4A3KE 2NVQF 3HOZF 4C3JF 4YFNE 2NVYF 2E2IF 5D4EE 2VUME 2VUMF 2A6HE 1HQME 2Y0SH 3S14F 3S14E 3PO3E 1TWHE 5C44E 3PO3F 2JA6E 4LLGE 3H3VG 3GTGE 4X6AE 4X6AF 2E2JF 4BXXE 5IP7E 5C3EF 5E17E 5M3MF 1Y1VF 1K83E 1Y1VE 1K83F 4A3LE 4C2MF 4C2ME 4C3HE 1QKLA 4OIRE 3GTPE 5IYCF 4YG2E 2NVXF 2NVXE 5IYDE 5IYDF 4A3IE 4A3CF 2A6EE 5D4DE 1SFOE 5M5WF 3M3YF 4BY1E 1DZFA 4XSZE 5M3FF 4AYBH 3HOVE 4XLNE 4Y7NF 2Y0SI 2R93E 1R9TE 5C4JF 5C4JE 1I50F 1I50E 1TWFF 1WCMF 4LK1E 5IYBF 5IYBE 2B63F 3HOWE 1I3QE 2YU9E 4AYBK 4A93F 4Q4ZE 3HOXF 4Y52F 2NVQE 3GTKF 3GTKE 5IP9F 5IP9E 4C3JE 1Y1WF 3HOZE 2NVYE 4A3JF 5M5YF 4A3JE 4MQ9E 4MEXE 2E2IE 2WB1H 2NVTF 2O5IE 4C3IF 3S1RF 3GTME 4LK0E 3H0GF 2E2HF 5C3EE 2E2JE 5M3ME 5C4XE 5C4XF 4MEYE 3S17F 3S17E 4LJZE 4Q5SE 5IYCE 2PPBE 4A3CE 1YNNK 2CW0E 5M5WE 1TWCE 1TWCF 4OIQE 3M3YE 4A3EF 5FJ8F 5TMFE 5FJ8E 1I6HF 4JK1E 5M3FE 4A3FF 5IPLE 4A3DE 3HOVF 4XLPE 4Y7NE 4G7HE 4BBRF 4A3DF 2WB1I 4QIWH 2A68E 3K7AE 3K7AF 3RZDF 1WCME 1TWFE 3RZDE 2B63E 2R92F 3S2DF 3S2DE 3S1NF 3S1NE 2JA8F 4A93E 5M5XF 3HOXE 3GTQE 3H3VF 3S16E 3S16F 4Y52E 4QIWK 4A3GF 1Y1WE 3GTLF 5M5YE 3HOUF 3I4NF 4OIOE 3M4OF 3M4OE 5FLMF 2NVTE 3GTQF 4C3IE 3S1RE 5TMCE 3GTJF 3I4MF 3I4ME 2E2HE 3H0GE 3HKZH 3S1QF 1I6VE 5BYHE 3RZOF 2R7ZE 2R7ZF 4GZYE 4KMUE 3S1MF 1TWGE 1TWGF 3PO2F 3HKZK 2JA5E 2JA5F 3GTOF 3GTOE 4A3EE 4YFXE 4YFKE 3EQLE 4KN4E 1I6HE 4A3FE 2PMZH 1TWAF 4OINE 3WODE 2A69E 4OIPE 4BBRE 5E18E 3GTMF 3CQZF 3CQZE 4G7ZE 2JA7F 4A3KF 2KRXA 4A3ME 4A3MF 2R92E 4BY7F 4BY7E 1SMYE 2JA8E 2PMZK 1TWHF 5M5XE 5C44F 3S15E 3S15F 3DXJE 2JA6F 3GTGF 4A3GE 1YNJK 4BXXF 5IP7F 3GTLE 3HOUE 3I4NE 2BE5E 5FLME 4A3LF 4C3HF 3GTPF
chains in the Genus database with same CATH topology
4A3BF 4A3IF 1SFOF 4BY1F 4XSXE 1IW7E 4G7OE 3S2HF 2R93F 2O5JE 1R9TF 3HOWF 2WAQK 1ZYRE 4ZH4E 1I3QF 5D4CE 3FKIF 4KN7E 2YU9F 3HOYF 2NVQF 3HOZF 4C3JF 4YFNE 2NVYF 2E2IF 5D4EE 2VUMF 2A6HE 1HQME 3S14F 3PO3F 4LLGE 3H3VG 4X6AF 2E2JF 5C3EF 5E17E 5M3MF 1Y1VF 1K83F 4C2MF 1QKLA 4OIRE 5IYCF 4YG2E 2NVXF 4A3CF 5IYDF 2A6EE 5D4DE 5M5WF 3M3YF 4XSZE 5M3FF 4XLNE 4Y7NF 2Y0SI 5C4JF 1I50F 1WCMF 1TWFF 2B63F 4LK1E 5IYBF 4AYBK 4A93F 4Q4ZE 3HOXF 4Y52F 3GTKF 5IP9F 1Y1WF 4BBSF 4A3JF 5M5YF 4MEXE 4MQ9E 2NVTF 2O5IE 4C3IF 3S1RF 4LK0E 3H0GF 2E2HF 5C4XF 4MEYE 3S17F 4LJZE 4Q5SE 2PPBE 1YNNK 2CW0E 1TWCF 4OIQE 4A3EF 5FJ8F 5TMFE 1I6HF 4JK1E 4A3FF 5IPLE 4A3DF 3HOVF 4XLPE 4G7HE 4BBRF 2WB1I 2A68E 3K7AF 3RZDF 2R92F 3S2DF 3S1NF 2JA8F 5M5XF 3S16F 4QIWK 4A3GF 3GTLF 3HOUF 3I4NF 4OIOE 3M4OF 5FLMF 3GTQF 5TMCE 3GTJF 3I4MF 3S1QF 1I6VE 5BYHE 3RZOF 2R7ZF 4GZYE 4KMUE 3S1MF 1TWGF 3PO2F 3HKZK 2JA5F 3GTOF 4YFXE 4YFKE 3EQLE 4KN4E 1TWAF 4OINE 3WODE 2A69E 4OIPE 5E18E 3GTMF 3CQZF 4G7ZE 2JA7F 4A3KF 2KRXA 4A3MF 4BY7F 1SMYE 2PMZK 1TWHF 5C44F 3S15F 3DXJE 2JA6F 3GTGF 1YNJK 4BXXF 5IP7F 2BE5E 4A3LF 4C3HF 3GTPF
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4A3B F;  4A3I F;  1SFO F;  4BY1 F;  4XSX E;  1IW7 E;  4G7O E;  3S2H F;  2R93 F;  2O5J E;  1R9T F;  3HOW F;  2WAQ K;  1ZYR E;  4ZH4 E;  1I3Q F;  5D4C E;  3FKI F;  4KN7 E;  2YU9 F;  3HOY F;  2NVQ F;  3HOZ F;  4C3J F;  4YFN E;  2NVY F;  2E2I F;  5D4E E;  2VUM F;  2A6H E;  1HQM E;  3S14 F;  3PO3 F;  4LLG E;  3H3V G;  4X6A F;  2E2J F;  5C3E F;  5E17 E;  5M3M F;  1Y1V F;  1K83 F;  4C2M F;  1QKL A;  4OIR E;  5IYC F;  4YG2 E;  2NVX F;  4A3C F;  5IYD F;  2A6E E;  5D4D E;  5M5W F;  3M3Y F;  4XSZ E;  5M3F F;  4XLN E;  4Y7N F;  2Y0S I;  5C4J F;  1I50 F;  1WCM F;  1TWF F;  2B63 F;  4LK1 E;  5IYB F;  4AYB K;  4A93 F;  4Q4Z E;  3HOX F;  4Y52 F;  3GTK F;  5IP9 F;  1Y1W F;  4BBS F;  4A3J F;  5M5Y F;  4MEX E;  4MQ9 E;  2NVT F;  2O5I E;  4C3I F;  3S1R F;  4LK0 E;  3H0G F;  2E2H F;  5C4X F;  4MEY E;  3S17 F;  4LJZ E;  4Q5S E;  2PPB E;  1YNN K;  2CW0 E;  1TWC F;  4OIQ E;  4A3E F;  5FJ8 F;  5TMF E;  1I6H F;  4JK1 E;  4A3F F;  5IPL E;  4A3D F;  3HOV F;  4XLP E;  4G7H E;  4BBR F;  2WB1 I;  2A68 E;  3K7A F;  3RZD F;  2R92 F;  3S2D F;  3S1N F;  2JA8 F;  5M5X F;  3S16 F;  4A3G F;  3GTL F;  3HOU F;  3I4N F;  4OIO E;  3M4O F;  5FLM F;  3GTQ F;  5TMC E;  3GTJ F;  3I4M F;  3S1Q F;  1I6V E;  5BYH E;  3RZO F;  2R7Z F;  4GZY E;  4KMU E;  3S1M F;  1TWG F;  3PO2 F;  3HKZ K;  2JA5 F;  3GTO F;  4YFX E;  4YFK E;  3EQL E;  4KN4 E;  1TWA F;  4OIN E;  3WOD E;  2A69 E;  4OIP E;  5E18 E;  3GTM F;  3CQZ F;  4G7Z E;  2JA7 F;  4A3K F;  4A3M F;  4BY7 F;  1SMY E;  2PMZ K;  1TWH F;  5C44 F;  3S15 F;  3DXJ E;  2JA6 F;  3GTG F;  1YNJ K;  4BXX F;  5IP7 F;  2BE5 E;  4A3L F;  4C3H F;  3GTP F; 
#chains in the Genus database with same CATH topology
 3GTJ E;  4A3B F;  4A3B E;  4A3I F;  4BBS F;  1SFO F;  3S1Q E;  4BY1 F;  4BBS E;  2WAQ H;  3RZO E;  4XSX E;  1IW7 E;  4G7O E;  1EIK A;  3S1M E;  3S2H F;  3S2H E;  3PO2 E;  2R93 F;  2O5J E;  1R9T F;  3HOW F;  2WAQ K;  1ZYR E;  4ZH4 E;  1TWA E;  1I3Q F;  5D4C E;  4KN7 E;  3FKI F;  3FKI E;  2YU9 F;  2JA7 E;  3HOY E;  3HOY F;  4A3K E;  2NVQ F;  3HOZ F;  4C3J F;  4YFN E;  2NVY F;  2E2I F;  5D4E E;  2VUM E;  2VUM F;  2A6H E;  1HQM E;  2Y0S H;  3S14 F;  3S14 E;  3PO3 E;  1TWH E;  5C44 E;  3PO3 F;  2JA6 E;  4LLG E;  3H3V G;  3GTG E;  4X6A E;  4X6A F;  2E2J F;  4BXX E;  5IP7 E;  5C3E F;  5E17 E;  5M3M F;  1Y1V F;  1K83 E;  1Y1V E;  1K83 F;  4A3L E;  4C2M F;  4C2M E;  4C3H E;  1QKL A;  4OIR E;  3GTP E;  5IYC F;  4YG2 E;  2NVX F;  2NVX E;  5IYD E;  5IYD F;  4A3I E;  4A3C F;  2A6E E;  5D4D E;  1SFO E;  5M5W F;  3M3Y F;  4BY1 E;  1DZF A;  4XSZ E;  5M3F F;  4AYB H;  3HOV E;  4XLN E;  4Y7N F;  2Y0S I;  2R93 E;  1R9T E;  5C4J F;  5C4J E;  1I50 F;  1I50 E;  1TWF F;  1WCM F;  4LK1 E;  5IYB F;  5IYB E;  2B63 F;  3HOW E;  1I3Q E;  2YU9 E;  4AYB K;  4A93 F;  4Q4Z E;  3HOX F;  4Y52 F;  2NVQ E;  3GTK F;  3GTK E;  5IP9 F;  5IP9 E;  4C3J E;  1Y1W F;  3HOZ E;  2NVY E;  4A3J F;  5M5Y F;  4A3J E;  4MQ9 E;  4MEX E;  2E2I E;  2WB1 H;  2NVT F;  2O5I E;  4C3I F;  3S1R F;  3GTM E;  4LK0 E;  3H0G F;  2E2H F;  5C3E E;  2E2J E;  5M3M E;  5C4X E;  5C4X F;  4MEY E;  3S17 F;  3S17 E;  4LJZ E;  4Q5S E;  5IYC E;  2PPB E;  4A3C E;  1YNN K;  2CW0 E;  5M5W E;  1TWC E;  1TWC F;  4OIQ E;  3M3Y E;  4A3E F;  5FJ8 F;  5TMF E;  5FJ8 E;  1I6H F;  4JK1 E;  5M3F E;  4A3F F;  5IPL E;  4A3D E;  3HOV F;  4XLP E;  4Y7N E;  4G7H E;  4BBR F;  4A3D F;  2WB1 I;  4QIW H;  2A68 E;  3K7A E;  3K7A F;  3RZD F;  1WCM E;  1TWF E;  3RZD E;  2B63 E;  2R92 F;  3S2D F;  3S2D E;  3S1N F;  3S1N E;  2JA8 F;  4A93 E;  5M5X F;  3HOX E;  3GTQ E;  3H3V F;  3S16 E;  3S16 F;  4Y52 E;  4QIW K;  4A3G F;  1Y1W E;  3GTL F;  5M5Y E;  3HOU F;  3I4N F;  4OIO E;  3M4O F;  3M4O E;  5FLM F;  2NVT E;  3GTQ F;  4C3I E;  3S1R E;  5TMC E;  3GTJ F;  3I4M F;  3I4M E;  2E2H E;  3H0G E;  3HKZ H;  3S1Q F;  1I6V E;  5BYH E;  3RZO F;  2R7Z E;  2R7Z F;  4GZY E;  4KMU E;  3S1M F;  1TWG E;  1TWG F;  3PO2 F;  3HKZ K;  2JA5 E;  2JA5 F;  3GTO F;  3GTO E;  4A3E E;  4YFX E;  4YFK E;  3EQL E;  4KN4 E;  1I6H E;  4A3F E;  2PMZ H;  1TWA F;  4OIN E;  3WOD E;  2A69 E;  4OIP E;  4BBR E;  5E18 E;  3GTM F;  3CQZ F;  3CQZ E;  4G7Z E;  2JA7 F;  4A3K F;  2KRX A;  4A3M E;  4A3M F;  2R92 E;  4BY7 F;  4BY7 E;  1SMY E;  2JA8 E;  2PMZ K;  1TWH F;  5M5X E;  5C44 F;  3S15 E;  3S15 F;  3DXJ E;  2JA6 F;  3GTG F;  4A3G E;  1YNJ K;  4BXX F;  5IP7 F;  3GTL E;  3HOU E;  3I4N E;  2BE5 E;  5FLM E;  4A3L F;  4C3H F;  3GTP F; 
#chains in the Genus database with same CATH homology
 4A3B F;  4A3I F;  1SFO F;  4BY1 F;  4XSX E;  1IW7 E;  4G7O E;  3S2H F;  2R93 F;  2O5J E;  1R9T F;  3HOW F;  2WAQ K;  1ZYR E;  4ZH4 E;  1I3Q F;  5D4C E;  3FKI F;  4KN7 E;  2YU9 F;  3HOY F;  2NVQ F;  3HOZ F;  4C3J F;  4YFN E;  2NVY F;  2E2I F;  5D4E E;  2VUM F;  2A6H E;  1HQM E;  3S14 F;  3PO3 F;  4LLG E;  3H3V G;  4X6A F;  2E2J F;  5C3E F;  5E17 E;  5M3M F;  1Y1V F;  1K83 F;  4C2M F;  1QKL A;  4OIR E;  5IYC F;  4YG2 E;  2NVX F;  4A3C F;  5IYD F;  2A6E E;  5D4D E;  5M5W F;  3M3Y F;  4XSZ E;  5M3F F;  4XLN E;  4Y7N F;  2Y0S I;  5C4J F;  1I50 F;  1WCM F;  1TWF F;  2B63 F;  4LK1 E;  5IYB F;  4AYB K;  4A93 F;  4Q4Z E;  3HOX F;  4Y52 F;  3GTK F;  5IP9 F;  1Y1W F;  4BBS F;  4A3J F;  5M5Y F;  4MEX E;  4MQ9 E;  2NVT F;  2O5I E;  4C3I F;  3S1R F;  4LK0 E;  3H0G F;  2E2H F;  5C4X F;  4MEY E;  3S17 F;  4LJZ E;  4Q5S E;  2PPB E;  1YNN K;  2CW0 E;  1TWC F;  4OIQ E;  4A3E F;  5FJ8 F;  5TMF E;  1I6H F;  4JK1 E;  4A3F F;  5IPL E;  4A3D F;  3HOV F;  4XLP E;  4G7H E;  4BBR F;  2WB1 I;  2A68 E;  3K7A F;  3RZD F;  2R92 F;  3S2D F;  3S1N F;  2JA8 F;  5M5X F;  3S16 F;  4QIW K;  4A3G F;  3GTL F;  3HOU F;  3I4N F;  4OIO E;  3M4O F;  5FLM F;  3GTQ F;  5TMC E;  3GTJ F;  3I4M F;  3S1Q F;  1I6V E;  5BYH E;  3RZO F;  2R7Z F;  4GZY E;  4KMU E;  3S1M F;  1TWG F;  3PO2 F;  3HKZ K;  2JA5 F;  3GTO F;  4YFX E;  4YFK E;  3EQL E;  4KN4 E;  1TWA F;  4OIN E;  3WOD E;  2A69 E;  4OIP E;  5E18 E;  3GTM F;  3CQZ F;  4G7Z E;  2JA7 F;  4A3K F;  2KRX A;  4A3M F;  4BY7 F;  1SMY E;  2PMZ K;  1TWH F;  5C44 F;  3S15 F;  3DXJ E;  2JA6 F;  3GTG F;  1YNJ K;  4BXX F;  5IP7 F;  2BE5 E;  4A3L F;  4C3H F;  3GTP F; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...