4XLNE

Crystal structure of t. aquaticus transcription initiation complex containing bubble promoter and rna
Total Genus 20
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
20
sequence length
93
structure length
93
Chain Sequence
AEPGIDKLFGMVDSKYRLTVVVAKRAQQLLRHRFKNTVLEPEERPKMRTLEGLYDDPNAVTWAMKELLTGRLFFGENLVPEDRLQKEMERLYP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of a bacterial RNA polymerase holoenzyme open promoter complex.
pubmed doi rcsb
molecule tags Transcription/dna/rna
source organism Thermus aquaticus
molecule keywords DNA-directed RNA polymerase subunit alpha
total genus 20
structure length 93
sequence length 93
chains with identical sequence K
ec nomenclature ec 2.7.7.6: DNA-directed RNA polymerase.
pdb deposition date 2015-01-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF01192 RNA_pol_Rpb6 RNA polymerase Rpb6
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.940.10 Alpha Beta Alpha-Beta Complex Eukaryotic RPB6 RNA polymerase subunit Eukaryotic RPB6 RNA polymerase subunit 4xlnE00
4KN4E 5D4EE 5M5WF 3PO3F 5TMFE 3S17F 3HOYF 2R7ZF 3HOUF 5D4DE 4OIPE 3S1NF 4C3JF 3DXJE 4A3MF 2B63F 4YFXE 3GTMF 4A3FF 4XSZE 3HOZF 5E18E 4Q4ZE 1Y1WF 4MEYE 5C4XF 2A6EE 4Y7NF 4LK0E 1YNNK 1I50F 1HQME 4OINE 3S15F 2WAQK 2A68E 2JA7F 4X6AF 1K83F 4ZH4E 3M3YF 4BXXF 4C3IF 3S2HF 3CQZF 3H0GF 1TWAF 1TWCF 5M5YF 2O5IE 5E17E 4YFKE 3GTJF 2E2JF 4OIOE 2PMZK 3HKZK 4Y52F 4A3CF 3HOWF 3RZOF 3GTGF 4MEXE 5BYHE 5M3FF 3GTPF 3S16F 3EQLE 3GTOF 2BE5E 4JK1E 1SMYE 5C44F 2WB1I 4G7OE 4A3BF 4YFNE 4G7ZE 1R9TF 1I6VE 5TMCE 4BY7F 5IPLE 1SFOF 3S1RF 4G7HE 2NVQF 3S1QF 3I4NF 3WODE 4BY1F 1ZYRE 5D4CE 2YU9F 4Q5SE 2CW0E 2Y0SI 3RZDF 1YNJK 5IYDF 4A93F 2E2IF 1I3QF 5C3EF 3S1MF 2JA6F 4KMUE 4C3HF 2A69E 4YG2E 4AYBK 4A3JF 3M4OF 5FLMF 4OIRE 2R93F 5IP9F 3PO2F 3S14F 4A3IF 5IYBF 5IYCF 4A3KF 4A3GF 2PPBE 4LK1E 2NVXF 4BBRF 3HOVF 4A3DF 3FKIF 2VUMF 1Y1VF 3S2DF 4OIQE 4XLNE 4BBSF 4GZYE 3I4MF 5M5XF 2R92F 1TWHF 4XSXE 4A3LF 4A3EF 1TWGF 5FJ8F 2E2HF 3H3VG 4MQ9E 3GTLF 4KN7E 1IW7E 3K7AF 2NVTF 2A6HE 2JA5F 3GTKF 2O5JE 1TWFF 5IP7F 5M3MF 4LJZE 1WCMF 3HOXF 4XLPE 4LLGE 4C2MF 2JA8F 1I6HF 3GTQF 5C4JF 2NVYF 1QKLA
chains in the Genus database with same CATH superfamily
2YU9E 4KN4E 5D4EE 5M5WF 3S2HE 3RZDE 3CQZE 5TMFE 5IYDE 3S17F 3PO3F 3HOYF 3H0GE 4A93E 2E2IE 2R7ZF 3HOUF 5D4DE 1I3QE 4OIPE 4C3JF 2E2JE 3S1NF 3DXJE 5C3EE 4A3MF 4YFXE 2B63F 3GTMF 4A3FF 4XSZE 5M3FE 3HOZF 5E18E 4Q4ZE 1Y1WF 4MEYE 5C4XF 2A6EE 4C3HE 4LK0E 4Y7NF 1YNNK 1I50F 1HQME 4OINE 3S15F 2WAQK 4A3JE 3M4OE 4A3BE 2A68E 2JA7F 4X6AF 1K83F 4ZH4E 2WAQH 5IP9E 3M3YF 4C3IF 4BXXF 1SFOE 3S14E 3S1RE 3S2HF 3CQZF 5IYBE 3H0GF 1TWAF 1TWCF 5M5YF 2O5IE 5IYCE 4YFKE 3GTJF 5E17E 4A3KE 4A3GE 2E2JF 4OIOE 2PMZK 3HKZK 4Y52F 4A3CF 3HOWF 3RZOF 3GTGF 4MEXE 5BYHE 4BBRE 2PMZH 5M3FF 2KRXA 3GTPF 4A3DE 3FKIE 3S16F 3EQLE 3GTOF 2BE5E 4JK1E 1SMYE 5C44F 2VUME 1Y1VE 3S2DE 2WB1I 4G7OE 3S1ME 4YFNE 2JA6E 4G7ZE 4A3BF 1R9TF 1I6VE 5TMCE 4BY7F 4BBSE 5IPLE 3I4ME 2R92E 1TWHE 1SFOF 3S1RF 4G7HE 2NVQF 3S1QF 3I4NF 3WODE 2E2HE 5FLME 3GTLE 4BY1F 1ZYRE 2WB1H 2R93E 5D4CE 3K7AE 2NVTE 2JA5E 2YU9F 3PO2E 4Q5SE 2CW0E 2Y0SI 5IP7E 3RZDF 1YNJK 5IYDF 1WCME 3HOXE 4A3IE 4A93F 2E2IF 4QIWK 4C2ME 1I3QF 2JA8E 1I6HE 3GTQE 5C3EF 5C4JE 2NVXE 4QIWH 3S1MF 2NVYE 2JA6F 3HOVE 3HKZH 4KMUE 4C3HF 2Y0SH 3PO3E 3S17E 3HOYE 3H3VF 2A69E 4YG2E 3HOUE 4AYBK 4A3JF 3M4OF 5FLMF 4C3JE 3S1NE 4A3ME 4OIRE 2B63E 3GTME 2R93F 4A3FE 5IP9F 5M5XE 3PO2F 3HOZE 1Y1WE 3S14F 4A3LE 4A3EE 5C4XE 1TWGE 5FJ8E 4Y7NE 4A3IF 5IYBF 1I50E 5IYCF 4A3KF 4A3GF 2PPBE 2JA7E 3GTKE 4LK1E 2NVXF 1K83E 4X6AE 1TWFE 4BXXE 4BBRF 4C3IE 5M3ME 3HOVF 4A3DF 3FKIF 2VUMF 1Y1VF 1TWAE 1TWCE 5M5YE 3S2DF 3GTJE 4A3CE 4OIQE 4Y52E 4XLNE 3HOWE 4BBSF 3RZOE 3GTGE 5M5WE 4GZYE 3I4MF 5M5XF 2R92F 1TWHF 4XSXE 3GTPE 4A3EF 4A3LF 1TWGF 5FJ8F 3GTOE 3S16E 5C44E 2R7ZE 1DZFA 2E2HF 3H3VG 4MQ9E 3GTLF 4KN7E 4AYBH 1IW7E 3K7AF 1R9TE 2A6HE 2JA5F 2NVTF 3GTKF 4BY7E 2O5JE 1TWFF 5IP7F 5M3MF 1EIKA 4LJZE 1WCMF 3HOXF 2NVQE 4XLPE 3S1QE 3I4NE 3S15E 4LLGE 4C2MF 2JA8F 1I6HF 3GTQF 4BY1E 5C4JF 3M3YE 2NVYF 1QKLA
chains in the Genus database with same CATH topology
4KN4E 5D4EE 5M5WF 3PO3F 5TMFE 3S17F 3HOYF 2R7ZF 3HOUF 5D4DE 4OIPE 3S1NF 4C3JF 3DXJE 4A3MF 2B63F 4YFXE 3GTMF 4A3FF 4XSZE 3HOZF 5E18E 4Q4ZE 1Y1WF 4MEYE 5C4XF 2A6EE 4Y7NF 4LK0E 1YNNK 1I50F 1HQME 4OINE 3S15F 2WAQK 2A68E 2JA7F 4X6AF 1K83F 4ZH4E 3M3YF 4BXXF 4C3IF 3S2HF 3CQZF 3H0GF 1TWAF 1TWCF 5M5YF 2O5IE 5E17E 4YFKE 3GTJF 2E2JF 4OIOE 2PMZK 3HKZK 4Y52F 4A3CF 3HOWF 3RZOF 3GTGF 4MEXE 5BYHE 5M3FF 2KRXA 3GTPF 3S16F 3EQLE 3GTOF 2BE5E 4JK1E 1SMYE 5C44F 2WB1I 4G7OE 4A3BF 4YFNE 4G7ZE 1R9TF 1I6VE 5TMCE 4BY7F 5IPLE 1SFOF 3S1RF 4G7HE 2NVQF 3S1QF 3I4NF 3WODE 4BY1F 1ZYRE 5D4CE 2YU9F 4Q5SE 2CW0E 2Y0SI 3RZDF 1YNJK 5IYDF 4A93F 2E2IF 4QIWK 1I3QF 5C3EF 3S1MF 2JA6F 4KMUE 4C3HF 2A69E 4YG2E 4AYBK 4A3JF 3M4OF 5FLMF 4OIRE 2R93F 5IP9F 3PO2F 3S14F 4A3IF 5IYBF 5IYCF 4A3KF 4A3GF 2PPBE 4LK1E 2NVXF 4BBRF 3HOVF 4A3DF 3FKIF 2VUMF 1Y1VF 3S2DF 4OIQE 4XLNE 4BBSF 4GZYE 3I4MF 5M5XF 2R92F 1TWHF 4XSXE 4A3LF 4A3EF 1TWGF 5FJ8F 2E2HF 3H3VG 4MQ9E 3GTLF 4KN7E 1IW7E 3K7AF 2NVTF 2A6HE 2JA5F 3GTKF 2O5JE 1TWFF 5IP7F 5M3MF 4LJZE 1WCMF 3HOXF 4XLPE 4LLGE 4C2MF 2JA8F 1I6HF 3GTQF 5C4JF 2NVYF 1QKLA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4KN4 E;  5D4E E;  5M5W F;  3PO3 F;  5TMF E;  3S17 F;  3HOY F;  2R7Z F;  3HOU F;  5D4D E;  4OIP E;  3S1N F;  4C3J F;  3DXJ E;  4A3M F;  2B63 F;  4YFX E;  3GTM F;  4A3F F;  4XSZ E;  3HOZ F;  5E18 E;  4Q4Z E;  1Y1W F;  4MEY E;  5C4X F;  2A6E E;  4Y7N F;  4LK0 E;  1YNN K;  1I50 F;  1HQM E;  4OIN E;  3S15 F;  2WAQ K;  2A68 E;  2JA7 F;  4X6A F;  1K83 F;  4ZH4 E;  3M3Y F;  4BXX F;  4C3I F;  3S2H F;  3CQZ F;  3H0G F;  1TWA F;  1TWC F;  5M5Y F;  2O5I E;  5E17 E;  4YFK E;  3GTJ F;  2E2J F;  4OIO E;  2PMZ K;  3HKZ K;  4Y52 F;  4A3C F;  3HOW F;  3RZO F;  3GTG F;  4MEX E;  5BYH E;  5M3F F;  3GTP F;  3S16 F;  3EQL E;  3GTO F;  2BE5 E;  4JK1 E;  1SMY E;  5C44 F;  2WB1 I;  4G7O E;  4A3B F;  4YFN E;  4G7Z E;  1R9T F;  1I6V E;  5TMC E;  4BY7 F;  5IPL E;  1SFO F;  3S1R F;  4G7H E;  2NVQ F;  3S1Q F;  3I4N F;  3WOD E;  4BY1 F;  1ZYR E;  5D4C E;  2YU9 F;  4Q5S E;  2CW0 E;  2Y0S I;  3RZD F;  1YNJ K;  5IYD F;  4A93 F;  2E2I F;  1I3Q F;  5C3E F;  3S1M F;  2JA6 F;  4KMU E;  4C3H F;  2A69 E;  4YG2 E;  4AYB K;  4A3J F;  3M4O F;  5FLM F;  4OIR E;  2R93 F;  5IP9 F;  3PO2 F;  3S14 F;  4A3I F;  5IYB F;  5IYC F;  4A3K F;  4A3G F;  2PPB E;  4LK1 E;  2NVX F;  4BBR F;  3HOV F;  4A3D F;  3FKI F;  2VUM F;  1Y1V F;  3S2D F;  4OIQ E;  4XLN E;  4BBS F;  4GZY E;  3I4M F;  5M5X F;  2R92 F;  1TWH F;  4XSX E;  4A3L F;  4A3E F;  1TWG F;  5FJ8 F;  2E2H F;  3H3V G;  4MQ9 E;  3GTL F;  4KN7 E;  1IW7 E;  3K7A F;  2NVT F;  2A6H E;  2JA5 F;  3GTK F;  2O5J E;  1TWF F;  5IP7 F;  5M3M F;  4LJZ E;  1WCM F;  3HOX F;  4XLP E;  4LLG E;  4C2M F;  2JA8 F;  1I6H F;  3GTQ F;  5C4J F;  2NVY F;  1QKL A; 
#chains in the Genus database with same CATH topology
 2YU9 E;  4KN4 E;  5D4E E;  5M5W F;  3S2H E;  3RZD E;  3CQZ E;  5TMF E;  5IYD E;  3S17 F;  3PO3 F;  3HOY F;  3H0G E;  4A93 E;  2E2I E;  2R7Z F;  3HOU F;  5D4D E;  1I3Q E;  4OIP E;  4C3J F;  2E2J E;  3S1N F;  3DXJ E;  5C3E E;  4A3M F;  4YFX E;  2B63 F;  3GTM F;  4A3F F;  4XSZ E;  5M3F E;  3HOZ F;  5E18 E;  4Q4Z E;  1Y1W F;  4MEY E;  5C4X F;  2A6E E;  4C3H E;  4LK0 E;  4Y7N F;  1YNN K;  1I50 F;  1HQM E;  4OIN E;  3S15 F;  2WAQ K;  4A3J E;  3M4O E;  4A3B E;  2A68 E;  2JA7 F;  4X6A F;  1K83 F;  4ZH4 E;  2WAQ H;  5IP9 E;  3M3Y F;  4C3I F;  4BXX F;  1SFO E;  3S14 E;  3S1R E;  3S2H F;  3CQZ F;  5IYB E;  3H0G F;  1TWA F;  1TWC F;  5M5Y F;  2O5I E;  5IYC E;  4YFK E;  3GTJ F;  5E17 E;  4A3K E;  4A3G E;  2E2J F;  4OIO E;  2PMZ K;  3HKZ K;  4Y52 F;  4A3C F;  3HOW F;  3RZO F;  3GTG F;  4MEX E;  5BYH E;  4BBR E;  2PMZ H;  5M3F F;  2KRX A;  3GTP F;  4A3D E;  3FKI E;  3S16 F;  3EQL E;  3GTO F;  2BE5 E;  4JK1 E;  1SMY E;  5C44 F;  2VUM E;  1Y1V E;  3S2D E;  2WB1 I;  4G7O E;  3S1M E;  4YFN E;  2JA6 E;  4G7Z E;  4A3B F;  1R9T F;  1I6V E;  5TMC E;  4BY7 F;  4BBS E;  5IPL E;  3I4M E;  2R92 E;  1TWH E;  1SFO F;  3S1R F;  4G7H E;  2NVQ F;  3S1Q F;  3I4N F;  3WOD E;  2E2H E;  5FLM E;  3GTL E;  4BY1 F;  1ZYR E;  2WB1 H;  2R93 E;  5D4C E;  3K7A E;  2NVT E;  2JA5 E;  2YU9 F;  3PO2 E;  4Q5S E;  2CW0 E;  2Y0S I;  5IP7 E;  3RZD F;  1YNJ K;  5IYD F;  1WCM E;  3HOX E;  4A3I E;  4A93 F;  2E2I F;  4QIW K;  4C2M E;  1I3Q F;  2JA8 E;  1I6H E;  3GTQ E;  5C3E F;  5C4J E;  2NVX E;  4QIW H;  3S1M F;  2NVY E;  2JA6 F;  3HOV E;  3HKZ H;  4KMU E;  4C3H F;  2Y0S H;  3PO3 E;  3S17 E;  3HOY E;  3H3V F;  2A69 E;  4YG2 E;  3HOU E;  4AYB K;  4A3J F;  3M4O F;  5FLM F;  4C3J E;  3S1N E;  4A3M E;  4OIR E;  2B63 E;  3GTM E;  2R93 F;  4A3F E;  5IP9 F;  5M5X E;  3PO2 F;  3HOZ E;  1Y1W E;  3S14 F;  4A3L E;  4A3E E;  5C4X E;  1TWG E;  5FJ8 E;  4Y7N E;  4A3I F;  5IYB F;  1I50 E;  5IYC F;  4A3K F;  4A3G F;  2PPB E;  2JA7 E;  3GTK E;  4LK1 E;  2NVX F;  1K83 E;  4X6A E;  1TWF E;  4BXX E;  4BBR F;  4C3I E;  5M3M E;  3HOV F;  4A3D F;  3FKI F;  2VUM F;  1Y1V F;  1TWA E;  1TWC E;  5M5Y E;  3S2D F;  3GTJ E;  4A3C E;  4OIQ E;  4Y52 E;  4XLN E;  3HOW E;  4BBS F;  3RZO E;  3GTG E;  5M5W E;  4GZY E;  3I4M F;  5M5X F;  2R92 F;  1TWH F;  4XSX E;  3GTP E;  4A3E F;  4A3L F;  1TWG F;  5FJ8 F;  3GTO E;  3S16 E;  5C44 E;  2R7Z E;  1DZF A;  2E2H F;  3H3V G;  4MQ9 E;  3GTL F;  4KN7 E;  4AYB H;  1IW7 E;  3K7A F;  1R9T E;  2A6H E;  2JA5 F;  2NVT F;  3GTK F;  4BY7 E;  2O5J E;  1TWF F;  5IP7 F;  5M3M F;  1EIK A;  4LJZ E;  1WCM F;  3HOX F;  2NVQ E;  4XLP E;  3S1Q E;  3I4N E;  3S15 E;  4LLG E;  4C2M F;  2JA8 F;  1I6H F;  3GTQ F;  4BY1 E;  5C4J F;  3M3Y E;  2NVY F;  1QKL A; 
#chains in the Genus database with same CATH homology
 4KN4 E;  5D4E E;  5M5W F;  3PO3 F;  5TMF E;  3S17 F;  3HOY F;  2R7Z F;  3HOU F;  5D4D E;  4OIP E;  3S1N F;  4C3J F;  3DXJ E;  4A3M F;  2B63 F;  4YFX E;  3GTM F;  4A3F F;  4XSZ E;  3HOZ F;  5E18 E;  4Q4Z E;  1Y1W F;  4MEY E;  5C4X F;  2A6E E;  4Y7N F;  4LK0 E;  1YNN K;  1I50 F;  1HQM E;  4OIN E;  3S15 F;  2WAQ K;  2A68 E;  2JA7 F;  4X6A F;  1K83 F;  4ZH4 E;  3M3Y F;  4BXX F;  4C3I F;  3S2H F;  3CQZ F;  3H0G F;  1TWA F;  1TWC F;  5M5Y F;  2O5I E;  5E17 E;  4YFK E;  3GTJ F;  2E2J F;  4OIO E;  2PMZ K;  3HKZ K;  4Y52 F;  4A3C F;  3HOW F;  3RZO F;  3GTG F;  4MEX E;  5BYH E;  5M3F F;  2KRX A;  3GTP F;  3S16 F;  3EQL E;  3GTO F;  2BE5 E;  4JK1 E;  1SMY E;  5C44 F;  2WB1 I;  4G7O E;  4A3B F;  4YFN E;  4G7Z E;  1R9T F;  1I6V E;  5TMC E;  4BY7 F;  5IPL E;  1SFO F;  3S1R F;  4G7H E;  2NVQ F;  3S1Q F;  3I4N F;  3WOD E;  4BY1 F;  1ZYR E;  5D4C E;  2YU9 F;  4Q5S E;  2CW0 E;  2Y0S I;  3RZD F;  1YNJ K;  5IYD F;  4A93 F;  2E2I F;  4QIW K;  1I3Q F;  5C3E F;  3S1M F;  2JA6 F;  4KMU E;  4C3H F;  2A69 E;  4YG2 E;  4AYB K;  4A3J F;  3M4O F;  5FLM F;  4OIR E;  2R93 F;  5IP9 F;  3PO2 F;  3S14 F;  4A3I F;  5IYB F;  5IYC F;  4A3K F;  4A3G F;  2PPB E;  4LK1 E;  2NVX F;  4BBR F;  3HOV F;  4A3D F;  3FKI F;  2VUM F;  1Y1V F;  3S2D F;  4OIQ E;  4XLN E;  4BBS F;  4GZY E;  3I4M F;  5M5X F;  2R92 F;  1TWH F;  4XSX E;  4A3L F;  4A3E F;  1TWG F;  5FJ8 F;  2E2H F;  3H3V G;  4MQ9 E;  3GTL F;  4KN7 E;  1IW7 E;  3K7A F;  2NVT F;  2A6H E;  2JA5 F;  3GTK F;  2O5J E;  1TWF F;  5IP7 F;  5M3M F;  4LJZ E;  1WCM F;  3HOX F;  4XLP E;  4LLG E;  4C2M F;  2JA8 F;  1I6H F;  3GTQ F;  5C4J F;  2NVY F;  1QKL A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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