4Y7NE

The structure insight into 5-carboxycytosine recognition by rna polymerase ii during transcription elongation.
Total Genus 53
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
53
sequence length
214
structure length
214
Chain Sequence
DQENERNISRLWRAFRTVKEMVKDRGYFITQEEVELPLEDFKAKYCDSMGRPQRKMMSFQANPTEESISKFPDMGSLWVEFCDEPSVGVKTMKTFVIHIQEKNFQTGIFVYQNNITPSAMKLVPSIPPATIETFNEAALVVNITHHELVPKHIRLSSDEKRELLKRYRLKESQLPRIQRADPVALYLGLKRGEVVKIIRKSETSGRYASYRICM
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Molecular basis for 5-carboxycytosine recognition by RNA polymerase II elongation complex.
pubmed doi rcsb
molecule tags Transcription/dna/rna
molecule keywords DNA-directed RNA polymerase II subunit RPB1
total genus 53
structure length 214
sequence length 214
ec nomenclature
pdb deposition date 2015-02-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF01191 RNA_pol_Rpb5_C RNA polymerase Rpb5, C-terminal domain
E PF03871 RNA_pol_Rpb5_N RNA polymerase Rpb5, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1340.10 Alpha Beta 3-Layer(aba) Sandwich Dna-directed Rna Polymerases I, Ii, And Iii 27 Kd Polypeptide; Chain: A; domain 1 RNA polymerase, Rpb5, N-terminal domain 4y7nE01
3.90.940.20 Alpha Beta Alpha-Beta Complex Eukaryotic RPB6 RNA polymerase subunit RPB5-like RNA polymerase subunit 4y7nE02
2JA5E 4AYBH 1DZFA 4BBSE 4A3KE 3HOYE 4A3GE 5M3ME 2R92E 4BXXE 3S2DE 5FJ8E 4Y7NE 3K7AE 3GTME 3CQZE 1TWCE 4A3IE 5C4XE 1TWAE 3S15E 5IYBE 2E2HE 5C3EE 3HOVE 2NVXE 2PMZH 4A3EE 3RZDE 5M3FE 3S2HE 3S14E 3HOZE 2WB1H 1R9TE 4QIWH 5M5WE 1SFOE 4C3HE 5IP9E 3S1QE 4A3ME 2JA6E 1TWHE 4C3JE 3GTOE 5IP7E 2NVQE 1WCME 4X6AE 2NVYE 2E2IE 5C4JE 3HOXE 4BBRE 4BY7E 3M3YE 2R93E 3M4OE 1TWFE 3HOWE 3I4NE 1Y1WE 4A3FE 5M5XE 5IYDE 2JA8E 3H3VF 5C44E 4A3JE 3GTPE 4A3LE 3HOUE 4Y52E 3S1ME 2Y0SH 4C2ME 3RZOE 1K83E 4C3IE 1I3QE 2B63E 1I50E 4A3DE 3S1NE 3S17E 2VUME 4BY1E 1EIKA 2JA7E 3GTLE 3I4ME 5IYCE 4A3BE 1I6HE 1Y1VE 3S1RE 3GTGE 4A93E 3H0GE 3HKZH 5FLME 3S16E 3PO3E 3GTQE 3PO2E 2YU9E 5M5YE 2WAQH 3GTJE 2E2JE 3GTKE 2R7ZE 1TWGE 2NVTE 3FKIE 4A3CE
chains in the Genus database with same CATH superfamily
2JA5E 4AYBH 2PMZK 2VUMF 3HOWF 2BE5E 1DZFA 4BBSE 4OIPE 4A3KE 3EQLE 2JA7F 3I4MF 4A3FF 5M5XF 3HOYE 1Y1VF 4A3GE 3S1RF 5M3ME 2R92E 3GTGF 4A93F 4OIRE 4BXXE 4QIWK 3S2DE 5FJ8E 4Y7NE 5C44F 3K7AE 3GTME 3PO3F 3GTQF 4A3JF 2YU9F 3GTPF 3PO2F 5M5YF 2A6HE 3HOUF 3CQZE 1TWCE 4A3IE 5C4XE 4OIOE 4C2MF 2Y0SI 1TWAE 4LK1E 4JK1E 2E2JF 3GTKF 4GZYE 3S15E 1K83F 5IYBE 1IW7E 1TWGF 1I3QF 2E2HE 2NVTF 1I50F 3FKIF 4A3CF 2JA5F 1YNNK 4LLGE 5C3EE 4XLNE 3S1NF 4XLPE 2A68E 4ZH4E 3HOVE 2NVXE 2PMZH 4A3KF 3S17F 4A3EE 4BY1F 3RZDE 5M3FE 3S2HE 1HQME 2CW0E 4A3GF 3GTLF 4MQ9E 2R92F 3S14E 1YNJK 3HOZE 5IYCF 1I6HF 4A3BF 1QKLA 2WB1H 3S2DF 4Y7NF 5D4DE 1R9TE 4QIWH 3H0GF 5M5WE 1SFOE 4C3HE 5IP9E 3S1QE 5FLMF 4A3ME 3S16F 3CQZF 2JA6E 4YFXE 1TWHE 4C3JE 1TWCF 4A3IF 5C4XF 3GTOE 5IP7E 4KN7E 1TWAF 2NVQE 3GTJF 1WCME 4OINE 4X6AE 2NVYE 5IYBF 2E2IE 4MEYE 5C4JE 3HOXE 4BBRE 2E2HF 2R7ZF 4BY7E 3M3YE 4G7ZE 2R93E 5C3EF 3M4OE 1TWFE 3HOWE 4Q5SE 3HOVF 2NVXF 3H3VG 4YFKE 3I4NE 2A69E 1Y1WE 4BBSF 4MEXE 3S2HF 4A3FE 5M5XE 5IYDE 2O5JE 4YG2E 5E17E 3HOYF 3S14F 3HOZF 2JA8E 4Q4ZE 1ZYRE 5M3MF 1SMYE 3H3VF 4BXXF 2WB1I 3HKZK 5TMFE 4G7OE 5C44E 5M5WF 5FJ8F 5IPLE 4YFNE 3K7AF 5IP9F 4C3HF 3GTMF 3S1QF 4A3JE 3GTPE 2JA6F 4A3LE 3HOUE 1TWHF 2WAQK 4C3JF 4Y52E 3S1ME 5IP7F 2PPBE 2Y0SH 4C2ME 2NVQF 1WCMF 3RZOE 2NVYF 1K83E 5C4JF 4C3IE 4BBRF 3S15F 5BYHE 1I3QE 4BY7F 3M3YF 2B63E 3DXJE 2O5IE 1I50E 2R93F 4LK0E 3M4OF 1TWFF 4AYBK 4A3DE 4G7HE 3S1NE 3WODE 3I4NF 3S17E 2VUME 1Y1WF 4BY1E 5IYDF 4A3EF 1EIKA 4OIQE 3RZDF 2JA7E 5M3FF 3GTLE 3I4ME 4LJZE 2JA8F 5IYCE 4A3BE 1I6HE 1Y1VE 1I6VE 3S1RE 4KN4E 3GTGE 4A93E 5E18E 4KMUE 3H0GE 3HKZH 1R9TF 5FLME 3S16E 1SFOF 4A3LF 3PO3E 4A3MF 4Y52F 3GTQE 3PO2E 2YU9E 2A6EE 5D4CE 5M5YE 2WAQH 4XSZE 2KRXA 3S1MF 3GTOF 5TMCE 3RZOF 3GTJE 4XSXE 4C3IF 2E2JE 3GTKE 4X6AF 2E2IF 5D4EE 3HOXF 2R7ZE 2B63F 1TWGE 4A3DF 2NVTE 3FKIE 4A3CE
chains in the Genus database with same CATH topology
2JA5E 4AYBH 1DZFA 4BBSE 4A3KE 3HOYE 4A3GE 5M3ME 2R92E 4BXXE 3S2DE 5FJ8E 4Y7NE 3K7AE 3GTME 3CQZE 1TWCE 4A3IE 5C4XE 1TWAE 3S15E 5IYBE 2E2HE 5C3EE 3HOVE 2NVXE 2PMZH 4A3EE 3RZDE 5M3FE 3S2HE 3S14E 3HOZE 2WB1H 1R9TE 4QIWH 5M5WE 1SFOE 4C3HE 5IP9E 3S1QE 4A3ME 2JA6E 1TWHE 4C3JE 3GTOE 5IP7E 2NVQE 1WCME 4X6AE 2NVYE 2E2IE 5C4JE 3HOXE 4BBRE 4BY7E 3M3YE 2R93E 3M4OE 1TWFE 3HOWE 3I4NE 1Y1WE 4A3FE 5M5XE 5IYDE 2JA8E 3H3VF 5C44E 4A3JE 3GTPE 4A3LE 3HOUE 4Y52E 3S1ME 2Y0SH 4C2ME 3RZOE 1K83E 4C3IE 1I3QE 2B63E 1I50E 4A3DE 3S1NE 3S17E 2VUME 4BY1E 1EIKA 2JA7E 3GTLE 3I4ME 5IYCE 4A3BE 1I6HE 1Y1VE 3S1RE 3GTGE 4A93E 3H0GE 3HKZH 5FLME 3S16E 3PO3E 3GTQE 3PO2E 2YU9E 5M5YE 2WAQH 3GTJE 2E2JE 3GTKE 2R7ZE 1TWGE 2NVTE 3FKIE 4A3CE
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2JA5 E;  4AYB H;  1DZF A;  4BBS E;  4A3K E;  3HOY E;  4A3G E;  5M3M E;  2R92 E;  4BXX E;  3S2D E;  5FJ8 E;  4Y7N E;  3K7A E;  3GTM E;  3CQZ E;  1TWC E;  4A3I E;  5C4X E;  1TWA E;  3S15 E;  5IYB E;  2E2H E;  5C3E E;  3HOV E;  2NVX E;  2PMZ H;  4A3E E;  3RZD E;  5M3F E;  3S2H E;  3S14 E;  3HOZ E;  2WB1 H;  1R9T E;  4QIW H;  5M5W E;  1SFO E;  4C3H E;  5IP9 E;  3S1Q E;  4A3M E;  2JA6 E;  1TWH E;  4C3J E;  3GTO E;  5IP7 E;  2NVQ E;  1WCM E;  4X6A E;  2NVY E;  2E2I E;  5C4J E;  3HOX E;  4BBR E;  4BY7 E;  3M3Y E;  2R93 E;  3M4O E;  1TWF E;  3HOW E;  3I4N E;  1Y1W E;  4A3F E;  5M5X E;  5IYD E;  2JA8 E;  3H3V F;  5C44 E;  4A3J E;  3GTP E;  4A3L E;  3HOU E;  4Y52 E;  3S1M E;  2Y0S H;  4C2M E;  3RZO E;  1K83 E;  4C3I E;  1I3Q E;  2B63 E;  1I50 E;  4A3D E;  3S1N E;  3S17 E;  2VUM E;  4BY1 E;  1EIK A;  2JA7 E;  3GTL E;  3I4M E;  5IYC E;  4A3B E;  1I6H E;  1Y1V E;  3S1R E;  3GTG E;  4A93 E;  3H0G E;  3HKZ H;  5FLM E;  3S16 E;  3PO3 E;  3GTQ E;  3PO2 E;  2YU9 E;  5M5Y E;  2WAQ H;  3GTJ E;  2E2J E;  3GTK E;  2R7Z E;  1TWG E;  2NVT E;  3FKI E;  4A3C E; 
#chains in the Genus database with same CATH topology
 2JA5 E;  4AYB H;  2PMZ K;  2VUM F;  3HOW F;  2BE5 E;  1DZF A;  4BBS E;  4OIP E;  4A3K E;  3EQL E;  2JA7 F;  3I4M F;  4A3F F;  5M5X F;  3HOY E;  1Y1V F;  4A3G E;  3S1R F;  5M3M E;  2R92 E;  3GTG F;  4A93 F;  4OIR E;  4BXX E;  4QIW K;  3S2D E;  5FJ8 E;  4Y7N E;  5C44 F;  3K7A E;  3GTM E;  3PO3 F;  3GTQ F;  4A3J F;  2YU9 F;  3GTP F;  3PO2 F;  5M5Y F;  2A6H E;  3HOU F;  3CQZ E;  1TWC E;  4A3I E;  5C4X E;  4OIO E;  4C2M F;  2Y0S I;  1TWA E;  4LK1 E;  4JK1 E;  2E2J F;  3GTK F;  4GZY E;  3S15 E;  1K83 F;  5IYB E;  1IW7 E;  1TWG F;  1I3Q F;  2E2H E;  2NVT F;  1I50 F;  3FKI F;  4A3C F;  2JA5 F;  1YNN K;  4LLG E;  5C3E E;  4XLN E;  3S1N F;  4XLP E;  2A68 E;  4ZH4 E;  3HOV E;  2NVX E;  2PMZ H;  4A3K F;  3S17 F;  4A3E E;  4BY1 F;  3RZD E;  5M3F E;  3S2H E;  1HQM E;  2CW0 E;  4A3G F;  3GTL F;  4MQ9 E;  2R92 F;  3S14 E;  1YNJ K;  3HOZ E;  5IYC F;  1I6H F;  4A3B F;  1QKL A;  2WB1 H;  3S2D F;  4Y7N F;  5D4D E;  1R9T E;  4QIW H;  3H0G F;  5M5W E;  1SFO E;  4C3H E;  5IP9 E;  3S1Q E;  5FLM F;  4A3M E;  3S16 F;  3CQZ F;  2JA6 E;  4YFX E;  1TWH E;  4C3J E;  1TWC F;  4A3I F;  5C4X F;  3GTO E;  5IP7 E;  4KN7 E;  1TWA F;  2NVQ E;  3GTJ F;  1WCM E;  4OIN E;  4X6A E;  2NVY E;  5IYB F;  2E2I E;  4MEY E;  5C4J E;  3HOX E;  4BBR E;  2E2H F;  2R7Z F;  4BY7 E;  3M3Y E;  4G7Z E;  2R93 E;  5C3E F;  3M4O E;  1TWF E;  3HOW E;  4Q5S E;  3HOV F;  2NVX F;  3H3V G;  4YFK E;  3I4N E;  2A69 E;  1Y1W E;  4BBS F;  4MEX E;  3S2H F;  4A3F E;  5M5X E;  5IYD E;  2O5J E;  4YG2 E;  5E17 E;  3HOY F;  3S14 F;  3HOZ F;  2JA8 E;  4Q4Z E;  1ZYR E;  5M3M F;  1SMY E;  3H3V F;  4BXX F;  2WB1 I;  3HKZ K;  5TMF E;  4G7O E;  5C44 E;  5M5W F;  5FJ8 F;  5IPL E;  4YFN E;  3K7A F;  5IP9 F;  4C3H F;  3GTM F;  3S1Q F;  4A3J E;  3GTP E;  2JA6 F;  4A3L E;  3HOU E;  1TWH F;  2WAQ K;  4C3J F;  4Y52 E;  3S1M E;  5IP7 F;  2PPB E;  2Y0S H;  4C2M E;  2NVQ F;  1WCM F;  3RZO E;  2NVY F;  1K83 E;  5C4J F;  4C3I E;  4BBR F;  3S15 F;  5BYH E;  1I3Q E;  4BY7 F;  3M3Y F;  2B63 E;  3DXJ E;  2O5I E;  1I50 E;  2R93 F;  4LK0 E;  3M4O F;  1TWF F;  4AYB K;  4A3D E;  4G7H E;  3S1N E;  3WOD E;  3I4N F;  3S17 E;  2VUM E;  1Y1W F;  4BY1 E;  5IYD F;  4A3E F;  1EIK A;  4OIQ E;  3RZD F;  2JA7 E;  5M3F F;  3GTL E;  3I4M E;  4LJZ E;  2JA8 F;  5IYC E;  4A3B E;  1I6H E;  1Y1V E;  1I6V E;  3S1R E;  4KN4 E;  3GTG E;  4A93 E;  5E18 E;  4KMU E;  3H0G E;  3HKZ H;  1R9T F;  5FLM E;  3S16 E;  1SFO F;  4A3L F;  3PO3 E;  4A3M F;  4Y52 F;  3GTQ E;  3PO2 E;  2YU9 E;  2A6E E;  5D4C E;  5M5Y E;  2WAQ H;  4XSZ E;  2KRX A;  3S1M F;  3GTO F;  5TMC E;  3RZO F;  3GTJ E;  4XSX E;  4C3I F;  2E2J E;  3GTK E;  4X6A F;  2E2I F;  5D4E E;  3HOX F;  2R7Z E;  2B63 F;  1TWG E;  4A3D F;  2NVT E;  3FKI E;  4A3C E; 
#chains in the Genus database with same CATH homology
 2JA5 E;  4AYB H;  1DZF A;  4BBS E;  4A3K E;  3HOY E;  4A3G E;  5M3M E;  2R92 E;  4BXX E;  3S2D E;  5FJ8 E;  4Y7N E;  3K7A E;  3GTM E;  3CQZ E;  1TWC E;  4A3I E;  5C4X E;  1TWA E;  3S15 E;  5IYB E;  2E2H E;  5C3E E;  3HOV E;  2NVX E;  2PMZ H;  4A3E E;  3RZD E;  5M3F E;  3S2H E;  3S14 E;  3HOZ E;  2WB1 H;  1R9T E;  4QIW H;  5M5W E;  1SFO E;  4C3H E;  5IP9 E;  3S1Q E;  4A3M E;  2JA6 E;  1TWH E;  4C3J E;  3GTO E;  5IP7 E;  2NVQ E;  1WCM E;  4X6A E;  2NVY E;  2E2I E;  5C4J E;  3HOX E;  4BBR E;  4BY7 E;  3M3Y E;  2R93 E;  3M4O E;  1TWF E;  3HOW E;  3I4N E;  1Y1W E;  4A3F E;  5M5X E;  5IYD E;  2JA8 E;  3H3V F;  5C44 E;  4A3J E;  3GTP E;  4A3L E;  3HOU E;  4Y52 E;  3S1M E;  2Y0S H;  4C2M E;  3RZO E;  1K83 E;  4C3I E;  1I3Q E;  2B63 E;  1I50 E;  4A3D E;  3S1N E;  3S17 E;  2VUM E;  4BY1 E;  1EIK A;  2JA7 E;  3GTL E;  3I4M E;  5IYC E;  4A3B E;  1I6H E;  1Y1V E;  3S1R E;  3GTG E;  4A93 E;  3H0G E;  3HKZ H;  5FLM E;  3S16 E;  3PO3 E;  3GTQ E;  3PO2 E;  2YU9 E;  5M5Y E;  2WAQ H;  3GTJ E;  2E2J E;  3GTK E;  2R7Z E;  1TWG E;  2NVT E;  3FKI E;  4A3C E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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