4A3BE

Rna polymerase ii initial transcribing complex with a 4nt dna-rna hybrid
Total Genus 62
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
62
sequence length
214
structure length
214
Chain Sequence
DQENERNISRLWRAFRTVKEMVKDRGYFITQEEVELPLEDFKAKYCDSMGRPQRKMMSFQANPTEESISKFPDMGSLWVEFCDEPSVGVKTMKTFVIHIQEKNFQTGIFVYQNNITPSAMKLVPSIPPATIETFNEAALVVNITHHELVPKHIRLSSDEKRELLKRYRLKESQLPRIQRADPVALYLGLKRGEVVKIIRKSETSGRYASYRICM
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of initial RNA polymerase II transcription.
pubmed doi rcsb
molecule tags Transcription
molecule keywords DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1
total genus 62
structure length 214
sequence length 214
ec nomenclature
pdb deposition date 2011-09-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF01191 RNA_pol_Rpb5_C RNA polymerase Rpb5, C-terminal domain
E PF03871 RNA_pol_Rpb5_N RNA polymerase Rpb5, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1340.10 Alpha Beta 3-Layer(aba) Sandwich Dna-directed Rna Polymerases I, Ii, And Iii 27 Kd Polypeptide; Chain: A; domain 1 RNA polymerase, Rpb5, N-terminal domain 4a3bE01
3.90.940.20 Alpha Beta Alpha-Beta Complex Eukaryotic RPB6 RNA polymerase subunit RPB5-like RNA polymerase subunit 4a3bE02
3I4ME 2R93E 5M5XE 5FJ8E 4A3ME 3H3VF 4Y7NE 3RZDE 2E2IE 3S15E 2WAQH 4A3DE 3GTPE 3HOUE 2R7ZE 1SFOE 3PO2E 4A3EE 3GTME 3GTJE 4A3LE 1Y1VE 3S2HE 4C3IE 3S1QE 5IP7E 4A3IE 2E2JE 2R92E 3FKIE 5M5WE 5IYDE 1DZFA 3GTGE 2NVXE 3S14E 1I3QE 1TWCE 5C3EE 2JA5E 2PMZH 2B63E 3GTKE 2YU9E 5M3FE 1TWGE 5M3ME 4Y52E 4C2ME 1K83E 3HOWE 3RZOE 5C44E 2VUME 3S16E 3HOVE 4A93E 4C3JE 4BBRE 4AYBH 4A3KE 3HOZE 5IYCE 3S1ME 4A3CE 1TWHE 2JA6E 4C3HE 5IYBE 5FLME 4QIWH 1R9TE 5IP9E 5C4XE 2Y0SH 4BBSE 3S1RE 1Y1WE 5M5YE 3GTOE 3S2DE 3HOXE 1WCME 3I4NE 2NVQE 3H0GE 3M4OE 4X6AE 3M3YE 3PO3E 4A3GE 2NVTE 5C4JE 3S1NE 3HKZH 1I6HE 2NVYE 4A3BE 4A3JE 4BY7E 3S17E 2JA7E 4BXXE 4A3FE 2E2HE 2WB1H 1I50E 3K7AE 2JA8E 3CQZE 3HOYE 1TWFE 3GTLE 4BY1E 3GTQE 1TWAE 1EIKA
chains in the Genus database with same CATH superfamily
3I4ME 1SFOF 2R93E 4G7ZE 4A3EF 3GTMF 3S1NF 3GTJF 4G7OE 4A3LF 2PMZK 5M5XE 1Y1VF 2PPBE 4BBRF 5FJ8E 4A3ME 4XSXE 4LK0E 4C3IF 4LLGE 3S1QF 3H3VF 5IYCF 2A68E 4Y7NE 2KRXA 5IP7F 3RZDE 4A3IF 2E2JF 2R92F 4LJZE 2E2IE 2Y0SI 3S15E 2WAQH 5M5WF 4A3DE 4ZH4E 3GTPE 2NVXF 3GTGF 3S14F 1TWCF 3HOUE 5TMFE 2R7ZE 5C3EF 4AYBK 2JA5F 4OIQE 1SFOE 3PO2E 1YNNK 4A3EE 3GTME 5IP9F 2B63F 3GTKF 2YU9F 4MEYE 3GTJE 1IW7E 4XSZE 5M3FF 4A3LE 1TWGF 5M3MF 1Y1VE 4Y52F 4C2MF 3S2HE 1K83F 3HOWF 4C3IE 3S1QE 3RZOF 5C44F 2VUMF 5IP7E 3HOVF 3S16F 4QIWK 4A3IE 4A93F 2E2JE 2R92E 3FKIE 2O5JE 5M5WE 4C3JF 5IYDE 1ZYRE 1DZFA 3GTGE 4A3KF 2NVXE 2A69E 3HOZF 3S14E 1I3QE 1TWCE 5IPLE 5C3EE 4MQ9E 4KN4E 2JA5E 2PMZH 2B63E 3GTKE 3S1MF 2YU9E 2A6HE 4A3CF 1TWHF 2WB1I 5M3FE 4C3HF 2JA6F 3DXJE 1TWGE 5M3ME 4Y52E 4C2ME 5IYBF 1K83E 3HOWE 5FLMF 3RZOE 5C44E 1R9TF 5C4XF 1I6VE 2VUME 4BBSF 3S16E 3HOVE 1I50F 2BE5E 4KN7E 5D4EE 4A93E 3CQZF 3HKZK 3S1RF 4C3JE 4BBRE 2CW0E 1YNJK 4AYBH 4A3KE 3HOZE 5IYCE 5M5YF 1QKLA 1Y1WF 3GTOF 3S2DF 2R93F 3HOXF 3S1ME 1WCMF 4A3CE 4OIOE 3I4NF 1TWHE 2JA6E 4C3HE 2NVQF 3H0GF 4OIPE 5E17E 3M4OF 4X6AF 4A3MF 3M3YF 3PO3F 5IYBE 5FLME 1HQME 4QIWH 3WODE 4MEXE 4A3GF 2NVTF 5C4JF 1R9TE 5IP9E 5C4XE 2Y0SH 2NVYF 4YFXE 4Q5SE 4YFKE 4BBSE 1I6HF 4G7HE 4A3BF 4A3JF 4BY7F 4LK1E 3S1RE 3S17F 4YG2E 2JA7F 4BXXF 4A3FF 2E2HF 1Y1WE 5M5YE 3GTOE 3S2DE 3PO2F 3K7AF 2JA8F 3EQLE 3HOXE 1WCME 1TWFF 3GTLF 3I4NE 3HOYF 2NVQE 5TMCE 3H0GE 4KMUE 4BY1F 4OIRE 3M4OE 4X6AE 3M3YE 3PO3E 1TWAF 2A6EE 2WAQK 4A3GE 4XLNE 3GTQF 3I4MF 3S2HF 2NVTE 5C4JE 3S1NE 3HKZH 1I6HE 2NVYE 4Q4ZE 5D4CE 2O5IE 4A3BE 4A3JE 4BY7E 3FKIF 5M5XF 3S17E 5IYDF 5FJ8F 2JA7E 4BXXE 3H3VG 4GZYE 4A3FE 2E2HE 1I3QF 4Y7NF 2WB1H 1I50E 4OINE 3K7AE 2JA8E 3RZDF 5E18E 3CQZE 2E2IF 3S15F 3HOYE 1TWFE 3GTLE 5D4DE 1SMYE 4BY1E 4JK1E 4YFNE 3GTPF 4XLPE 4A3DF 3GTQE 3HOUF 5BYHE 1TWAE 2R7ZF 1EIKA
chains in the Genus database with same CATH topology
3I4ME 2R93E 5M5XE 5FJ8E 4A3ME 3H3VF 4Y7NE 3RZDE 2E2IE 3S15E 2WAQH 4A3DE 3GTPE 3HOUE 2R7ZE 1SFOE 3PO2E 4A3EE 3GTME 3GTJE 4A3LE 1Y1VE 3S2HE 4C3IE 3S1QE 5IP7E 4A3IE 2E2JE 2R92E 3FKIE 5M5WE 5IYDE 1DZFA 3GTGE 2NVXE 3S14E 1I3QE 1TWCE 5C3EE 2JA5E 2PMZH 2B63E 3GTKE 2YU9E 5M3FE 1TWGE 5M3ME 4Y52E 4C2ME 1K83E 3HOWE 3RZOE 5C44E 2VUME 3S16E 3HOVE 4A93E 4C3JE 4BBRE 4AYBH 4A3KE 3HOZE 5IYCE 3S1ME 4A3CE 1TWHE 2JA6E 4C3HE 5IYBE 5FLME 4QIWH 1R9TE 5IP9E 5C4XE 2Y0SH 4BBSE 3S1RE 1Y1WE 5M5YE 3GTOE 3S2DE 3HOXE 1WCME 3I4NE 2NVQE 3H0GE 3M4OE 4X6AE 3M3YE 3PO3E 4A3GE 2NVTE 5C4JE 3S1NE 3HKZH 1I6HE 2NVYE 4A3BE 4A3JE 4BY7E 3S17E 2JA7E 4BXXE 4A3FE 2E2HE 2WB1H 1I50E 3K7AE 2JA8E 3CQZE 3HOYE 1TWFE 3GTLE 4BY1E 3GTQE 1TWAE 1EIKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3I4M E;  2R93 E;  5M5X E;  5FJ8 E;  4A3M E;  3H3V F;  4Y7N E;  3RZD E;  2E2I E;  3S15 E;  2WAQ H;  4A3D E;  3GTP E;  3HOU E;  2R7Z E;  1SFO E;  3PO2 E;  4A3E E;  3GTM E;  3GTJ E;  4A3L E;  1Y1V E;  3S2H E;  4C3I E;  3S1Q E;  5IP7 E;  4A3I E;  2E2J E;  2R92 E;  3FKI E;  5M5W E;  5IYD E;  1DZF A;  3GTG E;  2NVX E;  3S14 E;  1I3Q E;  1TWC E;  5C3E E;  2JA5 E;  2PMZ H;  2B63 E;  3GTK E;  2YU9 E;  5M3F E;  1TWG E;  5M3M E;  4Y52 E;  4C2M E;  1K83 E;  3HOW E;  3RZO E;  5C44 E;  2VUM E;  3S16 E;  3HOV E;  4A93 E;  4C3J E;  4BBR E;  4AYB H;  4A3K E;  3HOZ E;  5IYC E;  3S1M E;  4A3C E;  1TWH E;  2JA6 E;  4C3H E;  5IYB E;  5FLM E;  4QIW H;  1R9T E;  5IP9 E;  5C4X E;  2Y0S H;  4BBS E;  3S1R E;  1Y1W E;  5M5Y E;  3GTO E;  3S2D E;  3HOX E;  1WCM E;  3I4N E;  2NVQ E;  3H0G E;  3M4O E;  4X6A E;  3M3Y E;  3PO3 E;  4A3G E;  2NVT E;  5C4J E;  3S1N E;  3HKZ H;  1I6H E;  2NVY E;  4A3B E;  4A3J E;  4BY7 E;  3S17 E;  2JA7 E;  4BXX E;  4A3F E;  2E2H E;  2WB1 H;  1I50 E;  3K7A E;  2JA8 E;  3CQZ E;  3HOY E;  1TWF E;  3GTL E;  4BY1 E;  3GTQ E;  1TWA E;  1EIK A; 
#chains in the Genus database with same CATH topology
 3I4M E;  1SFO F;  2R93 E;  4G7Z E;  4A3E F;  3GTM F;  3S1N F;  3GTJ F;  4G7O E;  4A3L F;  2PMZ K;  5M5X E;  1Y1V F;  2PPB E;  4BBR F;  5FJ8 E;  4A3M E;  4XSX E;  4LK0 E;  4C3I F;  4LLG E;  3S1Q F;  3H3V F;  5IYC F;  2A68 E;  4Y7N E;  2KRX A;  5IP7 F;  3RZD E;  4A3I F;  2E2J F;  2R92 F;  4LJZ E;  2E2I E;  2Y0S I;  3S15 E;  2WAQ H;  5M5W F;  4A3D E;  4ZH4 E;  3GTP E;  2NVX F;  3GTG F;  3S14 F;  1TWC F;  3HOU E;  5TMF E;  2R7Z E;  5C3E F;  4AYB K;  2JA5 F;  4OIQ E;  1SFO E;  3PO2 E;  1YNN K;  4A3E E;  3GTM E;  5IP9 F;  2B63 F;  3GTK F;  2YU9 F;  4MEY E;  3GTJ E;  1IW7 E;  4XSZ E;  5M3F F;  4A3L E;  1TWG F;  5M3M F;  1Y1V E;  4Y52 F;  4C2M F;  3S2H E;  1K83 F;  3HOW F;  4C3I E;  3S1Q E;  3RZO F;  5C44 F;  2VUM F;  5IP7 E;  3HOV F;  3S16 F;  4QIW K;  4A3I E;  4A93 F;  2E2J E;  2R92 E;  3FKI E;  2O5J E;  5M5W E;  4C3J F;  5IYD E;  1ZYR E;  1DZF A;  3GTG E;  4A3K F;  2NVX E;  2A69 E;  3HOZ F;  3S14 E;  1I3Q E;  1TWC E;  5IPL E;  5C3E E;  4MQ9 E;  4KN4 E;  2JA5 E;  2PMZ H;  2B63 E;  3GTK E;  3S1M F;  2YU9 E;  2A6H E;  4A3C F;  1TWH F;  2WB1 I;  5M3F E;  4C3H F;  2JA6 F;  3DXJ E;  1TWG E;  5M3M E;  4Y52 E;  4C2M E;  5IYB F;  1K83 E;  3HOW E;  5FLM F;  3RZO E;  5C44 E;  1R9T F;  5C4X F;  1I6V E;  2VUM E;  4BBS F;  3S16 E;  3HOV E;  1I50 F;  2BE5 E;  4KN7 E;  5D4E E;  4A93 E;  3CQZ F;  3HKZ K;  3S1R F;  4C3J E;  4BBR E;  2CW0 E;  1YNJ K;  4AYB H;  4A3K E;  3HOZ E;  5IYC E;  5M5Y F;  1QKL A;  1Y1W F;  3GTO F;  3S2D F;  2R93 F;  3HOX F;  3S1M E;  1WCM F;  4A3C E;  4OIO E;  3I4N F;  1TWH E;  2JA6 E;  4C3H E;  2NVQ F;  3H0G F;  4OIP E;  5E17 E;  3M4O F;  4X6A F;  4A3M F;  3M3Y F;  3PO3 F;  5IYB E;  5FLM E;  1HQM E;  4QIW H;  3WOD E;  4MEX E;  4A3G F;  2NVT F;  5C4J F;  1R9T E;  5IP9 E;  5C4X E;  2Y0S H;  2NVY F;  4YFX E;  4Q5S E;  4YFK E;  4BBS E;  1I6H F;  4G7H E;  4A3B F;  4A3J F;  4BY7 F;  4LK1 E;  3S1R E;  3S17 F;  4YG2 E;  2JA7 F;  4BXX F;  4A3F F;  2E2H F;  1Y1W E;  5M5Y E;  3GTO E;  3S2D E;  3PO2 F;  3K7A F;  2JA8 F;  3EQL E;  3HOX E;  1WCM E;  1TWF F;  3GTL F;  3I4N E;  3HOY F;  2NVQ E;  5TMC E;  3H0G E;  4KMU E;  4BY1 F;  4OIR E;  3M4O E;  4X6A E;  3M3Y E;  3PO3 E;  1TWA F;  2A6E E;  2WAQ K;  4A3G E;  4XLN E;  3GTQ F;  3I4M F;  3S2H F;  2NVT E;  5C4J E;  3S1N E;  3HKZ H;  1I6H E;  2NVY E;  4Q4Z E;  5D4C E;  2O5I E;  4A3B E;  4A3J E;  4BY7 E;  3FKI F;  5M5X F;  3S17 E;  5IYD F;  5FJ8 F;  2JA7 E;  4BXX E;  3H3V G;  4GZY E;  4A3F E;  2E2H E;  1I3Q F;  4Y7N F;  2WB1 H;  1I50 E;  4OIN E;  3K7A E;  2JA8 E;  3RZD F;  5E18 E;  3CQZ E;  2E2I F;  3S15 F;  3HOY E;  1TWF E;  3GTL E;  5D4D E;  1SMY E;  4BY1 E;  4JK1 E;  4YFN E;  3GTP F;  4XLP E;  4A3D F;  3GTQ E;  3HOU F;  5BYH E;  1TWA E;  2R7Z F;  1EIK A; 
#chains in the Genus database with same CATH homology
 3I4M E;  2R93 E;  5M5X E;  5FJ8 E;  4A3M E;  3H3V F;  4Y7N E;  3RZD E;  2E2I E;  3S15 E;  2WAQ H;  4A3D E;  3GTP E;  3HOU E;  2R7Z E;  1SFO E;  3PO2 E;  4A3E E;  3GTM E;  3GTJ E;  4A3L E;  1Y1V E;  3S2H E;  4C3I E;  3S1Q E;  5IP7 E;  4A3I E;  2E2J E;  2R92 E;  3FKI E;  5M5W E;  5IYD E;  1DZF A;  3GTG E;  2NVX E;  3S14 E;  1I3Q E;  1TWC E;  5C3E E;  2JA5 E;  2PMZ H;  2B63 E;  3GTK E;  2YU9 E;  5M3F E;  1TWG E;  5M3M E;  4Y52 E;  4C2M E;  1K83 E;  3HOW E;  3RZO E;  5C44 E;  2VUM E;  3S16 E;  3HOV E;  4A93 E;  4C3J E;  4BBR E;  4AYB H;  4A3K E;  3HOZ E;  5IYC E;  3S1M E;  4A3C E;  1TWH E;  2JA6 E;  4C3H E;  5IYB E;  5FLM E;  4QIW H;  1R9T E;  5IP9 E;  5C4X E;  2Y0S H;  4BBS E;  3S1R E;  1Y1W E;  5M5Y E;  3GTO E;  3S2D E;  3HOX E;  1WCM E;  3I4N E;  2NVQ E;  3H0G E;  3M4O E;  4X6A E;  3M3Y E;  3PO3 E;  4A3G E;  2NVT E;  5C4J E;  3S1N E;  3HKZ H;  1I6H E;  2NVY E;  4A3B E;  4A3J E;  4BY7 E;  3S17 E;  2JA7 E;  4BXX E;  4A3F E;  2E2H E;  2WB1 H;  1I50 E;  3K7A E;  2JA8 E;  3CQZ E;  3HOY E;  1TWF E;  3GTL E;  4BY1 E;  3GTQ E;  1TWA E;  1EIK A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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