4A3EF

Rna polymerase ii initial transcribing complex with a 5nt dna-rna hybrid and soaked with ampcpp
Total Genus 26
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
26
sequence length
84
structure length
84
Chain Sequence
KAIPKDQRATTPYMTKYERARILGTRALQISMNAPVFVDLEGETDPLRIAMKELAEKKIPLVIRRYLPDGSFEDWSVEELIVDL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of initial RNA polymerase II transcription.
pubmed doi rcsb
molecule tags Transcription
molecule keywords DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1
total genus 26
structure length 84
sequence length 84
ec nomenclature
pdb deposition date 2011-09-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
F PF01192 RNA_pol_Rpb6 RNA polymerase Rpb6
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.940.10 Alpha Beta Alpha-Beta Complex Eukaryotic RPB6 RNA polymerase subunit Eukaryotic RPB6 RNA polymerase subunit 4a3eF00
4Y7NF 1TWFF 3RZDF 3PO2F 3H0GF 2O5IE 4A3CF 2Y0SI 4A3JF 5BYHE 2O5JE 2B63F 4YG2E 4KMUE 3HOZF 3HOUF 2JA5F 1Y1WF 1SMYE 3CQZF 4A3DF 5E18E 4XSZE 1Y1VF 5TMCE 3S2HF 1TWGF 5TMFE 3WODE 3S1RF 4XLPE 3HKZK 4OIPE 4C2MF 4C3IF 4BBRF 1I6VE 4C3HF 3GTMF 2R93F 2R92F 3K7AF 4LLGE 3FKIF 3RZOF 1TWCF 2JA6F 4YFKE 3GTGF 1YNNK 1YNJK 3S17F 2WAQK 4LK0E 5M5WF 4A3FF 4A3LF 3EQLE 4Y52F 3GTLF 4A3MF 2E2HF 4MEXE 3GTPF 3S1QF 4A93F 2NVXF 2NVTF 1R9TF 3GTOF 4MEYE 4BXXF 3HOYF 1QKLA 5IYCF 3HOWF 3GTJF 1IW7E 2CW0E 4KN4E 4YFNE 3H3VG 2NVQF 4BBSF 4OIQE 2WB1I 1ZYRE 5M5YF 1HQME 2E2IF 4C3JF 4Q4ZE 2R7ZF 3M3YF 4X6AF 4LJZE 5IP9F 1I50F 5D4EE 5M3MF 4XLNE 5C4JF 1SFOF 5C44F 4YFXE 5IYDF 5C3EF 4A3IF 4A3BF 5FJ8F 3M4OF 3S1MF 1I6HF 2E2JF 3PO3F 4A3EF 4XSXE 3HOVF 5IPLE 2A6HE 5C4XF 4JK1E 4A3KF 5E17E 4G7ZE 4GZYE 4KN7E 5D4CE 2YU9F 4ZH4E 3S16F 1TWHF 4LK1E 3S1NF 5IYBF 2A6EE 2JA7F 1K83F 2VUMF 4G7HE 3DXJE 3S2DF 1TWAF 4BY7F 5M3FF 3I4MF 4A3GF 3S14F 2BE5E 1I3QF 2PMZK 4AYBK 4MQ9E 5M5XF 4OINE 4OIRE 4Q5SE 3GTKF 4BY1F 3HOXF 3GTQF 3I4NF 1WCMF 2A68E 3S15F 5D4DE 2A69E 2PPBE 2JA8F 4G7OE 5FLMF 2NVYF 4OIOE 5IP7F
chains in the Genus database with same CATH superfamily
4Y7NF 1TWFF 3RZDF 3PO2F 3H0GF 4C2ME 4C3IE 4BBRE 2O5IE 4A3CF 2Y0SI 4C3HE 4A3JF 5BYHE 3GTME 2R93E 2B63F 2R92E 2O5JE 4YG2E 4KMUE 3HOZF 3K7AE 3HOUF 2JA5F 2Y0SH 3FKIE 3RZOE 1TWCE 1Y1WF 1SMYE 2JA6E 3CQZF 3GTGE 4A3DF 5E18E 4Y7NE 4XSZE 3S17E 1Y1VF 5TMCE 3S2HF 1TWGF 5M5WE 4A3FE 4A3LE 5TMFE 3WODE 3S1RF 4XLPE 3HKZK 4QIWH 4OIPE 4C2MF 3GTLE 4A3ME 4C3IF 4BBRF 4Y52E 2E2HE 1I6VE 4C3HF 3GTMF 2R93F 4AYBH 2PMZH 2R92F 3GTPE 3K7AF 4LLGE 3FKIF 3RZOF 3S1QE 4A93E 1TWCF 2JA6F 2NVXE 2NVTE 4YFKE 1R9TE 3GTGF 3GTOE 1YNNK 1YNJK 3S17F 4BXXE 5IYCE 3HOWE 2WAQK 4LK0E 3GTJE 5M5WF 4A3FF 4A3LF 4BBSE 3EQLE 2NVQE 5M5YE 2E2IE 4Y52F 3GTLF 4A3MF 4C3JE 3M3YE 2R7ZE 4X6AE 2E2HF 4MEXE 3GTPF 5M3ME 3S1QF 4A93F 1SFOE 5C44E 2NVXF 2NVTF 1R9TF 5C3EE 4A3IE 3GTOF 4A3BE 5FJ8E 3M4OE 4MEYE 4BXXF 3HOYF 1QKLA 5IYCF 3HOWF 3S1ME 3GTJF 1IW7E 2CW0E 4KN4E 1I6HE 4YFNE 3H3VG 2E2JE 2NVQF 4OIQE 3PO3E 4BBSF 2WB1I 1ZYRE 5M5YF 1HQME 4A3EE 2E2IF 4C3JF 4Q4ZE 3HOVE 2R7ZF 3M3YF 4X6AF 4LJZE 5C4XE 2WB1H 5IP9F 4A3KE 1I50F 5D4EE 3HKZH 1EIKA 4QIWK 5M3MF 3HOYE 4XLNE 5C4JF 1SFOF 5C44F 2YU9E 4YFXE 5IYDF 5C3EF 4A3IF 4A3BF 3S16E 5FJ8F 3M4OF 1TWHE 3S1MF 1I6HF 3S1NE 5IYBE 2E2JF 5IP9E 3PO3F 2JA7E 1I50E 1K83E 4A3EF 2VUME 4XSXE 2WAQH 3HOVF 5IPLE 1DZFA 2A6HE 5C4XF 3S2DE 4JK1E 1TWAE 5C4JE 5M3FE 4A3KF 5IYDE 4G7ZE 3I4ME 4BY7E 3S14E 4GZYE 4A3GE 5E17E 1I3QE 4KN7E 5D4CE 5M5XE 2YU9F 4ZH4E 4BY1E 3S16F 1TWHF 3S1RE 4LK1E 3HOXE 3S1NF 5IYBF 3GTQE 1WCME 2A6EE 2JA7F 1K83F 2VUMF 4G7HE 3DXJE 3H3VF 3S15E 3S2DF 1TWAF 4BY7F 5M3FF 3I4MF 4A3GF 2JA8E 5FLME 3S14F 2NVYE 3I4NE 5IP7E 2BE5E 1I3QF 2PMZK 4AYBK 1TWFE 4MQ9E 5M5XF 3RZDE 4OINE 4OIRE 3PO2E 3H0GE 2KRXA 4Q5SE 3GTKF 4BY1F 4A3CE 4A3JE 2B63E 3HOZE 3HOXF 3HOUE 2JA5E 3GTQF 3I4NF 1WCMF 1Y1WE 2A68E 3CQZE 4A3DE 3S15F 1Y1VE 3S2HE 5D4DE 1TWGE 2A69E 2PPBE 3GTKE 2JA8F 4G7OE 5FLMF 2NVYF 4OIOE 5IP7F
chains in the Genus database with same CATH topology
4Y7NF 1TWFF 3RZDF 3PO2F 3H0GF 2O5IE 4A3CF 2Y0SI 4A3JF 5BYHE 2O5JE 2B63F 4YG2E 4KMUE 3HOZF 3HOUF 2JA5F 1Y1WF 1SMYE 3CQZF 4A3DF 5E18E 4XSZE 1Y1VF 5TMCE 3S2HF 1TWGF 5TMFE 3WODE 3S1RF 4XLPE 3HKZK 4OIPE 4C2MF 4C3IF 4BBRF 1I6VE 4C3HF 3GTMF 2R93F 2R92F 3K7AF 4LLGE 3FKIF 3RZOF 1TWCF 2JA6F 4YFKE 3GTGF 1YNNK 1YNJK 3S17F 2WAQK 4LK0E 5M5WF 4A3FF 4A3LF 3EQLE 4Y52F 3GTLF 4A3MF 2E2HF 4MEXE 3GTPF 3S1QF 4A93F 2NVXF 2NVTF 1R9TF 3GTOF 4MEYE 4BXXF 3HOYF 1QKLA 5IYCF 3HOWF 3GTJF 1IW7E 2CW0E 4KN4E 4YFNE 3H3VG 2NVQF 4BBSF 4OIQE 2WB1I 1ZYRE 5M5YF 1HQME 2E2IF 4C3JF 4Q4ZE 2R7ZF 3M3YF 4X6AF 4LJZE 5IP9F 1I50F 5D4EE 4QIWK 5M3MF 4XLNE 5C4JF 1SFOF 5C44F 4YFXE 5IYDF 5C3EF 4A3IF 4A3BF 5FJ8F 3M4OF 3S1MF 1I6HF 2E2JF 3PO3F 4A3EF 4XSXE 3HOVF 5IPLE 2A6HE 5C4XF 4JK1E 4A3KF 5E17E 4G7ZE 4GZYE 4KN7E 5D4CE 2YU9F 4ZH4E 3S16F 1TWHF 4LK1E 3S1NF 5IYBF 2A6EE 2JA7F 1K83F 2VUMF 4G7HE 3DXJE 3S2DF 1TWAF 4BY7F 5M3FF 3I4MF 4A3GF 3S14F 2BE5E 1I3QF 2PMZK 4AYBK 4MQ9E 5M5XF 4OINE 4OIRE 2KRXA 4Q5SE 3GTKF 4BY1F 3HOXF 3GTQF 3I4NF 1WCMF 2A68E 3S15F 5D4DE 2A69E 2PPBE 2JA8F 4G7OE 5FLMF 2NVYF 4OIOE 5IP7F
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4Y7N F;  1TWF F;  3RZD F;  3PO2 F;  3H0G F;  2O5I E;  4A3C F;  2Y0S I;  4A3J F;  5BYH E;  2O5J E;  2B63 F;  4YG2 E;  4KMU E;  3HOZ F;  3HOU F;  2JA5 F;  1Y1W F;  1SMY E;  3CQZ F;  4A3D F;  5E18 E;  4XSZ E;  1Y1V F;  5TMC E;  3S2H F;  1TWG F;  5TMF E;  3WOD E;  3S1R F;  4XLP E;  3HKZ K;  4OIP E;  4C2M F;  4C3I F;  4BBR F;  1I6V E;  4C3H F;  3GTM F;  2R93 F;  2R92 F;  3K7A F;  4LLG E;  3FKI F;  3RZO F;  1TWC F;  2JA6 F;  4YFK E;  3GTG F;  1YNN K;  1YNJ K;  3S17 F;  2WAQ K;  4LK0 E;  5M5W F;  4A3F F;  4A3L F;  3EQL E;  4Y52 F;  3GTL F;  4A3M F;  2E2H F;  4MEX E;  3GTP F;  3S1Q F;  4A93 F;  2NVX F;  2NVT F;  1R9T F;  3GTO F;  4MEY E;  4BXX F;  3HOY F;  1QKL A;  5IYC F;  3HOW F;  3GTJ F;  1IW7 E;  2CW0 E;  4KN4 E;  4YFN E;  3H3V G;  2NVQ F;  4BBS F;  4OIQ E;  2WB1 I;  1ZYR E;  5M5Y F;  1HQM E;  2E2I F;  4C3J F;  4Q4Z E;  2R7Z F;  3M3Y F;  4X6A F;  4LJZ E;  5IP9 F;  1I50 F;  5D4E E;  5M3M F;  4XLN E;  5C4J F;  1SFO F;  5C44 F;  4YFX E;  5IYD F;  5C3E F;  4A3I F;  4A3B F;  5FJ8 F;  3M4O F;  3S1M F;  1I6H F;  2E2J F;  3PO3 F;  4A3E F;  4XSX E;  3HOV F;  5IPL E;  2A6H E;  5C4X F;  4JK1 E;  4A3K F;  5E17 E;  4G7Z E;  4GZY E;  4KN7 E;  5D4C E;  2YU9 F;  4ZH4 E;  3S16 F;  1TWH F;  4LK1 E;  3S1N F;  5IYB F;  2A6E E;  2JA7 F;  1K83 F;  2VUM F;  4G7H E;  3DXJ E;  3S2D F;  1TWA F;  4BY7 F;  5M3F F;  3I4M F;  4A3G F;  3S14 F;  2BE5 E;  1I3Q F;  2PMZ K;  4AYB K;  4MQ9 E;  5M5X F;  4OIN E;  4OIR E;  4Q5S E;  3GTK F;  4BY1 F;  3HOX F;  3GTQ F;  3I4N F;  1WCM F;  2A68 E;  3S15 F;  5D4D E;  2A69 E;  2PPB E;  2JA8 F;  4G7O E;  5FLM F;  2NVY F;  4OIO E;  5IP7 F; 
#chains in the Genus database with same CATH topology
 4Y7N F;  1TWF F;  3RZD F;  3PO2 F;  3H0G F;  4C2M E;  4C3I E;  4BBR E;  2O5I E;  4A3C F;  2Y0S I;  4C3H E;  4A3J F;  5BYH E;  3GTM E;  2R93 E;  2B63 F;  2R92 E;  2O5J E;  4YG2 E;  4KMU E;  3HOZ F;  3K7A E;  3HOU F;  2JA5 F;  2Y0S H;  3FKI E;  3RZO E;  1TWC E;  1Y1W F;  1SMY E;  2JA6 E;  3CQZ F;  3GTG E;  4A3D F;  5E18 E;  4Y7N E;  4XSZ E;  3S17 E;  1Y1V F;  5TMC E;  3S2H F;  1TWG F;  5M5W E;  4A3F E;  4A3L E;  5TMF E;  3WOD E;  3S1R F;  4XLP E;  3HKZ K;  4QIW H;  4OIP E;  4C2M F;  3GTL E;  4A3M E;  4C3I F;  4BBR F;  4Y52 E;  2E2H E;  1I6V E;  4C3H F;  3GTM F;  2R93 F;  4AYB H;  2PMZ H;  2R92 F;  3GTP E;  3K7A F;  4LLG E;  3FKI F;  3RZO F;  3S1Q E;  4A93 E;  1TWC F;  2JA6 F;  2NVX E;  2NVT E;  4YFK E;  1R9T E;  3GTG F;  3GTO E;  1YNN K;  1YNJ K;  3S17 F;  4BXX E;  5IYC E;  3HOW E;  2WAQ K;  4LK0 E;  3GTJ E;  5M5W F;  4A3F F;  4A3L F;  4BBS E;  3EQL E;  2NVQ E;  5M5Y E;  2E2I E;  4Y52 F;  3GTL F;  4A3M F;  4C3J E;  3M3Y E;  2R7Z E;  4X6A E;  2E2H F;  4MEX E;  3GTP F;  5M3M E;  3S1Q F;  4A93 F;  1SFO E;  5C44 E;  2NVX F;  2NVT F;  1R9T F;  5C3E E;  4A3I E;  3GTO F;  4A3B E;  5FJ8 E;  3M4O E;  4MEY E;  4BXX F;  3HOY F;  1QKL A;  5IYC F;  3HOW F;  3S1M E;  3GTJ F;  1IW7 E;  2CW0 E;  4KN4 E;  1I6H E;  4YFN E;  3H3V G;  2E2J E;  2NVQ F;  4OIQ E;  3PO3 E;  4BBS F;  2WB1 I;  1ZYR E;  5M5Y F;  1HQM E;  4A3E E;  2E2I F;  4C3J F;  4Q4Z E;  3HOV E;  2R7Z F;  3M3Y F;  4X6A F;  4LJZ E;  5C4X E;  2WB1 H;  5IP9 F;  4A3K E;  1I50 F;  5D4E E;  3HKZ H;  1EIK A;  4QIW K;  5M3M F;  3HOY E;  4XLN E;  5C4J F;  1SFO F;  5C44 F;  2YU9 E;  4YFX E;  5IYD F;  5C3E F;  4A3I F;  4A3B F;  3S16 E;  5FJ8 F;  3M4O F;  1TWH E;  3S1M F;  1I6H F;  3S1N E;  5IYB E;  2E2J F;  5IP9 E;  3PO3 F;  2JA7 E;  1I50 E;  1K83 E;  4A3E F;  2VUM E;  4XSX E;  2WAQ H;  3HOV F;  5IPL E;  1DZF A;  2A6H E;  5C4X F;  3S2D E;  4JK1 E;  1TWA E;  5C4J E;  5M3F E;  4A3K F;  5IYD E;  4G7Z E;  3I4M E;  4BY7 E;  3S14 E;  4GZY E;  4A3G E;  5E17 E;  1I3Q E;  4KN7 E;  5D4C E;  5M5X E;  2YU9 F;  4ZH4 E;  4BY1 E;  3S16 F;  1TWH F;  3S1R E;  4LK1 E;  3HOX E;  3S1N F;  5IYB F;  3GTQ E;  1WCM E;  2A6E E;  2JA7 F;  1K83 F;  2VUM F;  4G7H E;  3DXJ E;  3H3V F;  3S15 E;  3S2D F;  1TWA F;  4BY7 F;  5M3F F;  3I4M F;  4A3G F;  2JA8 E;  5FLM E;  3S14 F;  2NVY E;  3I4N E;  5IP7 E;  2BE5 E;  1I3Q F;  2PMZ K;  4AYB K;  1TWF E;  4MQ9 E;  5M5X F;  3RZD E;  4OIN E;  4OIR E;  3PO2 E;  3H0G E;  2KRX A;  4Q5S E;  3GTK F;  4BY1 F;  4A3C E;  4A3J E;  2B63 E;  3HOZ E;  3HOX F;  3HOU E;  2JA5 E;  3GTQ F;  3I4N F;  1WCM F;  1Y1W E;  2A68 E;  3CQZ E;  4A3D E;  3S15 F;  1Y1V E;  3S2H E;  5D4D E;  1TWG E;  2A69 E;  2PPB E;  3GTK E;  2JA8 F;  4G7O E;  5FLM F;  2NVY F;  4OIO E;  5IP7 F; 
#chains in the Genus database with same CATH homology
 4Y7N F;  1TWF F;  3RZD F;  3PO2 F;  3H0G F;  2O5I E;  4A3C F;  2Y0S I;  4A3J F;  5BYH E;  2O5J E;  2B63 F;  4YG2 E;  4KMU E;  3HOZ F;  3HOU F;  2JA5 F;  1Y1W F;  1SMY E;  3CQZ F;  4A3D F;  5E18 E;  4XSZ E;  1Y1V F;  5TMC E;  3S2H F;  1TWG F;  5TMF E;  3WOD E;  3S1R F;  4XLP E;  3HKZ K;  4OIP E;  4C2M F;  4C3I F;  4BBR F;  1I6V E;  4C3H F;  3GTM F;  2R93 F;  2R92 F;  3K7A F;  4LLG E;  3FKI F;  3RZO F;  1TWC F;  2JA6 F;  4YFK E;  3GTG F;  1YNN K;  1YNJ K;  3S17 F;  2WAQ K;  4LK0 E;  5M5W F;  4A3F F;  4A3L F;  3EQL E;  4Y52 F;  3GTL F;  4A3M F;  2E2H F;  4MEX E;  3GTP F;  3S1Q F;  4A93 F;  2NVX F;  2NVT F;  1R9T F;  3GTO F;  4MEY E;  4BXX F;  3HOY F;  1QKL A;  5IYC F;  3HOW F;  3GTJ F;  1IW7 E;  2CW0 E;  4KN4 E;  4YFN E;  3H3V G;  2NVQ F;  4BBS F;  4OIQ E;  2WB1 I;  1ZYR E;  5M5Y F;  1HQM E;  2E2I F;  4C3J F;  4Q4Z E;  2R7Z F;  3M3Y F;  4X6A F;  4LJZ E;  5IP9 F;  1I50 F;  5D4E E;  4QIW K;  5M3M F;  4XLN E;  5C4J F;  1SFO F;  5C44 F;  4YFX E;  5IYD F;  5C3E F;  4A3I F;  4A3B F;  5FJ8 F;  3M4O F;  3S1M F;  1I6H F;  2E2J F;  3PO3 F;  4A3E F;  4XSX E;  3HOV F;  5IPL E;  2A6H E;  5C4X F;  4JK1 E;  4A3K F;  5E17 E;  4G7Z E;  4GZY E;  4KN7 E;  5D4C E;  2YU9 F;  4ZH4 E;  3S16 F;  1TWH F;  4LK1 E;  3S1N F;  5IYB F;  2A6E E;  2JA7 F;  1K83 F;  2VUM F;  4G7H E;  3DXJ E;  3S2D F;  1TWA F;  4BY7 F;  5M3F F;  3I4M F;  4A3G F;  3S14 F;  2BE5 E;  1I3Q F;  2PMZ K;  4AYB K;  4MQ9 E;  5M5X F;  4OIN E;  4OIR E;  2KRX A;  4Q5S E;  3GTK F;  4BY1 F;  3HOX F;  3GTQ F;  3I4N F;  1WCM F;  2A68 E;  3S15 F;  5D4D E;  2A69 E;  2PPB E;  2JA8 F;  4G7O E;  5FLM F;  2NVY F;  4OIO E;  5IP7 F; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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