4A3IE

Rna polymerase ii binary complex with dna
Total Genus 60
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
60
sequence length
214
structure length
214
Chain Sequence
DQENERNISRLWRAFRTVKEMVKDRGYFITQEEVELPLEDFKAKYCDSMGRPQRKMMSFQANPTEESISKFPDMGSLWVEFCDEPSVGVKTMKTFVIHIQEKNFQTGIFVYQNNITPSAMKLVPSIPPATIETFNEAALVVNITHHELVPKHIRLSSDEKRELLKRYRLKESQLPRIQRADPVALYLGLKRGEVVKIIRKSETSGRYASYRICM
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of initial RNA polymerase II transcription.
pubmed doi rcsb
molecule tags Transcription
molecule keywords DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1
total genus 60
structure length 214
sequence length 214
ec nomenclature
pdb deposition date 2011-09-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF01191 RNA_pol_Rpb5_C RNA polymerase Rpb5, C-terminal domain
E PF03871 RNA_pol_Rpb5_N RNA polymerase Rpb5, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1340.10 Alpha Beta 3-Layer(aba) Sandwich Dna-directed Rna Polymerases I, Ii, And Iii 27 Kd Polypeptide; Chain: A; domain 1 RNA polymerase, Rpb5, N-terminal domain 4a3iE01
3.90.940.20 Alpha Beta Alpha-Beta Complex Eukaryotic RPB6 RNA polymerase subunit RPB5-like RNA polymerase subunit 4a3iE02
3S1QE 3S1ME 5M5WE 4A3JE 2NVQE 3S16E 2VUME 5M5YE 3HOVE 3RZOE 3I4NE 1R9TE 4BBRE 4A3ME 5FLME 4A3KE 1DZFA 2NVTE 2B63E 3HOUE 3GTKE 3H3VF 3GTOE 5FJ8E 1SFOE 5IP7E 2PMZH 4BY1E 3S14E 2E2IE 3CQZE 4A3EE 5C4XE 3M3YE 2Y0SH 1Y1WE 4BBSE 3GTME 2JA7E 1TWHE 5IP9E 4BXXE 4A3FE 1I3QE 5C4JE 3HOZE 3PO2E 3I4ME 4A93E 1TWAE 1TWFE 2E2JE 3HOYE 2YU9E 1I50E 3HOXE 4A3DE 3S2HE 3GTLE 3GTJE 3H0GE 4A3CE 4Y7NE 2WB1H 1I6HE 3GTPE 4X6AE 5IYDE 4Y52E 2JA6E 3S15E 2R92E 1Y1VE 5C3EE 1EIKA 4C3HE 1TWGE 1K83E 1WCME 3M4OE 5IYBE 3HOWE 4A3IE 4C2ME 2NVXE 4C3JE 2JA8E 3S1NE 4BY7E 4C3IE 5M3ME 5C44E 4A3GE 4QIWH 2R93E 2R7ZE 4AYBH 2WAQH 3RZDE 2JA5E 3FKIE 3PO3E 5M5XE 3S1RE 3K7AE 3S2DE 3S17E 2E2HE 5IYCE 3GTQE 4A3LE 5M3FE 4A3BE 3HKZH 2NVYE 1TWCE 3GTGE
chains in the Genus database with same CATH superfamily
3S1QE 3S1ME 3S1NF 4BY7F 5M5WE 4A3JE 2NVQE 3S16E 4YG2E 4C3IF 5M3MF 5C44F 4A3GF 1I50F 2VUME 5M5YE 3HOVE 3RZOE 2R93F 3I4NE 4G7ZE 4GZYE 2R7ZF 1R9TE 5D4CE 4BBRE 4A3ME 1I6HF 3RZDF 4YFXE 5FLME 2O5IE 4A3KE 1QKLA 1DZFA 2A6EE 2NVTE 3FKIF 2B63E 3HOUE 3GTKE 3K7AF 3H3VF 3GTOE 3S1RF 5FJ8E 3S2DF 2O5JE 1SFOE 2Y0SI 2R92F 5IP7E 2PMZH 2E2HF 3S17F 5IYCF 4YFNE 3GTQF 4BY1E 1K83F 3WODE 4A3LF 2WB1I 5M3FF 3S14E 2NVYF 1TWCF 5E18E 1ZYRE 3GTGF 2E2IE 4QIWK 3CQZE 4Q4ZE 4OIPE 4A3EE 5C4XE 3S1MF 1SMYE 5M5WF 3M3YE 4A3JF 2NVQF 3S16F 4Q5SE 2Y0SH 4LK1E 1Y1WE 4XSZE 2VUMF 4BBSE 4LLGE 5M5YF 2PPBE 3HOVF 3RZOF 3I4NF 2WAQK 4KN7E 1YNNK 4OIRE 1R9TF 3GTME 4A3MF 2JA7E 5FLMF 2JA5F 4A3KF 5IPLE 1TWHE 2NVTF 2B63F 5IP9E 4BXXE 3GTKF 3HOUF 3GTOF 4A3FE 3HKZK 4KMUE 1I3QE 5IP7F 4G7HE 5C4JE 3HOZE 3EQLE 1IW7E 4BY1F 3PO2E 3I4ME 4A93E 3S14F 4A3BF 1TWAE 4MEXE 1TWFE 2E2JE 4OIQE 3HOYE 1HQME 2E2IF 3S1QF 2YU9E 4XLPE 1I50E 4A3EF 5C4XF 3HOXE 4A3DE 3S2HE 3M3YF 1Y1WF 4BBSF 4XSXE 3GTLE 3GTJE 3H0GE 4A3CE 4AYBK 4Y7NE 2KRXA 2WB1H 1I6HE 4ZH4E 3GTPE 4X6AE 5IYDE 5D4EE 2CW0E 3GTMF 5M5XF 4MQ9E 4BBRF 4Y52E 2PMZK 2JA7F 2JA6E 4LJZE 5E17E 3S15E 2R92E 1TWHF 1Y1VE 5C3EE 5IP9F 4BXXF 1EIKA 4C3HE 2A6HE 3DXJE 1TWGE 1K83E 4KN4E 5FJ8F 4A3FF 1WCME 3M4OE 1I3QF 1SFOF 5C4JF 5IYBE 3HOWE 3HOZF 4A3IE 4C2ME 2NVXE 4C3JE 2BE5E 3I4MF 3PO2F 4A93F 1TWAF 2JA8E 4LK0E 1TWFF 3S1NE 2E2JF 3HOYF 4BY7E 4C3IE 5M3ME 4JK1E 1YNJK 3CQZF 5C44E 2YU9F 4A3GE 2A68E 3HOXF 4QIWH 5BYHE 3S2HF 4G7OE 4A3DF 2R93E 5TMFE 4OIOE 3GTLF 3GTJF 3H0GF 3PO3F 3H3VG 4A3CF 1I6VE 2R7ZE 4Y7NF 4AYBH 2WAQH 3RZDE 2JA5E 3GTPF 5TMCE 5IYDF 4X6AF 3FKIE 3PO3E 5M5XE 3S1RE 3K7AE 4XLNE 4Y52F 3S2DE 2JA6F 3S15F 2A69E 3S17E 1Y1VF 5C3EF 2E2HE 4C3HF 5IYCE 1TWGF 3GTQE 1WCMF 4MEYE 4A3LE 4OINE 3M4OF 5M3FE 4A3BE 5IYBF 3HOWF 3HKZH 2NVYE 4YFKE 1TWCE 4A3IF 4C2MF 2NVXF 4C3JF 3GTGE 5D4DE 2JA8F
chains in the Genus database with same CATH topology
3S1QE 3S1ME 5M5WE 4A3JE 2NVQE 3S16E 2VUME 5M5YE 3HOVE 3RZOE 3I4NE 1R9TE 4BBRE 4A3ME 5FLME 4A3KE 1DZFA 2NVTE 2B63E 3HOUE 3GTKE 3H3VF 3GTOE 5FJ8E 1SFOE 5IP7E 2PMZH 4BY1E 3S14E 2E2IE 3CQZE 4A3EE 5C4XE 3M3YE 2Y0SH 1Y1WE 4BBSE 3GTME 2JA7E 1TWHE 5IP9E 4BXXE 4A3FE 1I3QE 5C4JE 3HOZE 3PO2E 3I4ME 4A93E 1TWAE 1TWFE 2E2JE 3HOYE 2YU9E 1I50E 3HOXE 4A3DE 3S2HE 3GTLE 3GTJE 3H0GE 4A3CE 4Y7NE 2WB1H 1I6HE 3GTPE 4X6AE 5IYDE 4Y52E 2JA6E 3S15E 2R92E 1Y1VE 5C3EE 1EIKA 4C3HE 1TWGE 1K83E 1WCME 3M4OE 5IYBE 3HOWE 4A3IE 4C2ME 2NVXE 4C3JE 2JA8E 3S1NE 4BY7E 4C3IE 5M3ME 5C44E 4A3GE 4QIWH 2R93E 2R7ZE 4AYBH 2WAQH 3RZDE 2JA5E 3FKIE 3PO3E 5M5XE 3S1RE 3K7AE 3S2DE 3S17E 2E2HE 5IYCE 3GTQE 4A3LE 5M3FE 4A3BE 3HKZH 2NVYE 1TWCE 3GTGE
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3S1Q E;  3S1M E;  5M5W E;  4A3J E;  2NVQ E;  3S16 E;  2VUM E;  5M5Y E;  3HOV E;  3RZO E;  3I4N E;  1R9T E;  4BBR E;  4A3M E;  5FLM E;  4A3K E;  1DZF A;  2NVT E;  2B63 E;  3HOU E;  3GTK E;  3H3V F;  3GTO E;  5FJ8 E;  1SFO E;  5IP7 E;  2PMZ H;  4BY1 E;  3S14 E;  2E2I E;  3CQZ E;  4A3E E;  5C4X E;  3M3Y E;  2Y0S H;  1Y1W E;  4BBS E;  3GTM E;  2JA7 E;  1TWH E;  5IP9 E;  4BXX E;  4A3F E;  1I3Q E;  5C4J E;  3HOZ E;  3PO2 E;  3I4M E;  4A93 E;  1TWA E;  1TWF E;  2E2J E;  3HOY E;  2YU9 E;  1I50 E;  3HOX E;  4A3D E;  3S2H E;  3GTL E;  3GTJ E;  3H0G E;  4A3C E;  4Y7N E;  2WB1 H;  1I6H E;  3GTP E;  4X6A E;  5IYD E;  4Y52 E;  2JA6 E;  3S15 E;  2R92 E;  1Y1V E;  5C3E E;  1EIK A;  4C3H E;  1TWG E;  1K83 E;  1WCM E;  3M4O E;  5IYB E;  3HOW E;  4A3I E;  4C2M E;  2NVX E;  4C3J E;  2JA8 E;  3S1N E;  4BY7 E;  4C3I E;  5M3M E;  5C44 E;  4A3G E;  4QIW H;  2R93 E;  2R7Z E;  4AYB H;  2WAQ H;  3RZD E;  2JA5 E;  3FKI E;  3PO3 E;  5M5X E;  3S1R E;  3K7A E;  3S2D E;  3S17 E;  2E2H E;  5IYC E;  3GTQ E;  4A3L E;  5M3F E;  4A3B E;  3HKZ H;  2NVY E;  1TWC E;  3GTG E; 
#chains in the Genus database with same CATH topology
 3S1Q E;  3S1M E;  3S1N F;  4BY7 F;  5M5W E;  4A3J E;  2NVQ E;  3S16 E;  4YG2 E;  4C3I F;  5M3M F;  5C44 F;  4A3G F;  1I50 F;  2VUM E;  5M5Y E;  3HOV E;  3RZO E;  2R93 F;  3I4N E;  4G7Z E;  4GZY E;  2R7Z F;  1R9T E;  5D4C E;  4BBR E;  4A3M E;  1I6H F;  3RZD F;  4YFX E;  5FLM E;  2O5I E;  4A3K E;  1QKL A;  1DZF A;  2A6E E;  2NVT E;  3FKI F;  2B63 E;  3HOU E;  3GTK E;  3K7A F;  3H3V F;  3GTO E;  3S1R F;  5FJ8 E;  3S2D F;  2O5J E;  1SFO E;  2Y0S I;  2R92 F;  5IP7 E;  2PMZ H;  2E2H F;  3S17 F;  5IYC F;  4YFN E;  3GTQ F;  4BY1 E;  1K83 F;  3WOD E;  4A3L F;  2WB1 I;  5M3F F;  3S14 E;  2NVY F;  1TWC F;  5E18 E;  1ZYR E;  3GTG F;  2E2I E;  4QIW K;  3CQZ E;  4Q4Z E;  4OIP E;  4A3E E;  5C4X E;  3S1M F;  1SMY E;  5M5W F;  3M3Y E;  4A3J F;  2NVQ F;  3S16 F;  4Q5S E;  2Y0S H;  4LK1 E;  1Y1W E;  4XSZ E;  2VUM F;  4BBS E;  4LLG E;  5M5Y F;  2PPB E;  3HOV F;  3RZO F;  3I4N F;  2WAQ K;  4KN7 E;  1YNN K;  4OIR E;  1R9T F;  3GTM E;  4A3M F;  2JA7 E;  5FLM F;  2JA5 F;  4A3K F;  5IPL E;  1TWH E;  2NVT F;  2B63 F;  5IP9 E;  4BXX E;  3GTK F;  3HOU F;  3GTO F;  4A3F E;  3HKZ K;  4KMU E;  1I3Q E;  5IP7 F;  4G7H E;  5C4J E;  3HOZ E;  3EQL E;  1IW7 E;  4BY1 F;  3PO2 E;  3I4M E;  4A93 E;  3S14 F;  4A3B F;  1TWA E;  4MEX E;  1TWF E;  2E2J E;  4OIQ E;  3HOY E;  1HQM E;  2E2I F;  3S1Q F;  2YU9 E;  4XLP E;  1I50 E;  4A3E F;  5C4X F;  3HOX E;  4A3D E;  3S2H E;  3M3Y F;  1Y1W F;  4BBS F;  4XSX E;  3GTL E;  3GTJ E;  3H0G E;  4A3C E;  4AYB K;  4Y7N E;  2KRX A;  2WB1 H;  1I6H E;  4ZH4 E;  3GTP E;  4X6A E;  5IYD E;  5D4E E;  2CW0 E;  3GTM F;  5M5X F;  4MQ9 E;  4BBR F;  4Y52 E;  2PMZ K;  2JA7 F;  2JA6 E;  4LJZ E;  5E17 E;  3S15 E;  2R92 E;  1TWH F;  1Y1V E;  5C3E E;  5IP9 F;  4BXX F;  1EIK A;  4C3H E;  2A6H E;  3DXJ E;  1TWG E;  1K83 E;  4KN4 E;  5FJ8 F;  4A3F F;  1WCM E;  3M4O E;  1I3Q F;  1SFO F;  5C4J F;  5IYB E;  3HOW E;  3HOZ F;  4A3I E;  4C2M E;  2NVX E;  4C3J E;  2BE5 E;  3I4M F;  3PO2 F;  4A93 F;  1TWA F;  2JA8 E;  4LK0 E;  1TWF F;  3S1N E;  2E2J F;  3HOY F;  4BY7 E;  4C3I E;  5M3M E;  4JK1 E;  1YNJ K;  3CQZ F;  5C44 E;  2YU9 F;  4A3G E;  2A68 E;  3HOX F;  4QIW H;  5BYH E;  3S2H F;  4G7O E;  4A3D F;  2R93 E;  5TMF E;  4OIO E;  3GTL F;  3GTJ F;  3H0G F;  3PO3 F;  3H3V G;  4A3C F;  1I6V E;  2R7Z E;  4Y7N F;  4AYB H;  2WAQ H;  3RZD E;  2JA5 E;  3GTP F;  5TMC E;  5IYD F;  4X6A F;  3FKI E;  3PO3 E;  5M5X E;  3S1R E;  3K7A E;  4XLN E;  4Y52 F;  3S2D E;  2JA6 F;  3S15 F;  2A69 E;  3S17 E;  1Y1V F;  5C3E F;  2E2H E;  4C3H F;  5IYC E;  1TWG F;  3GTQ E;  1WCM F;  4MEY E;  4A3L E;  4OIN E;  3M4O F;  5M3F E;  4A3B E;  5IYB F;  3HOW F;  3HKZ H;  2NVY E;  4YFK E;  1TWC E;  4A3I F;  4C2M F;  2NVX F;  4C3J F;  3GTG E;  5D4D E;  2JA8 F; 
#chains in the Genus database with same CATH homology
 3S1Q E;  3S1M E;  5M5W E;  4A3J E;  2NVQ E;  3S16 E;  2VUM E;  5M5Y E;  3HOV E;  3RZO E;  3I4N E;  1R9T E;  4BBR E;  4A3M E;  5FLM E;  4A3K E;  1DZF A;  2NVT E;  2B63 E;  3HOU E;  3GTK E;  3H3V F;  3GTO E;  5FJ8 E;  1SFO E;  5IP7 E;  2PMZ H;  4BY1 E;  3S14 E;  2E2I E;  3CQZ E;  4A3E E;  5C4X E;  3M3Y E;  2Y0S H;  1Y1W E;  4BBS E;  3GTM E;  2JA7 E;  1TWH E;  5IP9 E;  4BXX E;  4A3F E;  1I3Q E;  5C4J E;  3HOZ E;  3PO2 E;  3I4M E;  4A93 E;  1TWA E;  1TWF E;  2E2J E;  3HOY E;  2YU9 E;  1I50 E;  3HOX E;  4A3D E;  3S2H E;  3GTL E;  3GTJ E;  3H0G E;  4A3C E;  4Y7N E;  2WB1 H;  1I6H E;  3GTP E;  4X6A E;  5IYD E;  4Y52 E;  2JA6 E;  3S15 E;  2R92 E;  1Y1V E;  5C3E E;  1EIK A;  4C3H E;  1TWG E;  1K83 E;  1WCM E;  3M4O E;  5IYB E;  3HOW E;  4A3I E;  4C2M E;  2NVX E;  4C3J E;  2JA8 E;  3S1N E;  4BY7 E;  4C3I E;  5M3M E;  5C44 E;  4A3G E;  4QIW H;  2R93 E;  2R7Z E;  4AYB H;  2WAQ H;  3RZD E;  2JA5 E;  3FKI E;  3PO3 E;  5M5X E;  3S1R E;  3K7A E;  3S2D E;  3S17 E;  2E2H E;  5IYC E;  3GTQ E;  4A3L E;  5M3F E;  4A3B E;  3HKZ H;  2NVY E;  1TWC E;  3GTG E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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