4A3JE

Rna polymerase ii initial transcribing complex with a 2nt dna-rna hybrid and soaked with gmpcpp
Total Genus 61
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
61
sequence length
214
structure length
214
Chain Sequence
DQENERNISRLWRAFRTVKEMVKDRGYFITQEEVELPLEDFKAKYCDSMGRPQRKMMSFQANPTEESISKFPDMGSLWVEFCDEPSVGVKTMKTFVIHIQEKNFQTGIFVYQNNITPSAMKLVPSIPPATIETFNEAALVVNITHHELVPKHIRLSSDEKRELLKRYRLKESQLPRIQRADPVALYLGLKRGEVVKIIRKSETSGRYASYRICM
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Basis of Initial RNA Polymerase II Transcription.
pubmed doi rcsb
molecule tags Transcription
molecule keywords DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1
total genus 61
structure length 214
sequence length 214
ec nomenclature
pdb deposition date 2011-09-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF01191 RNA_pol_Rpb5_C RNA polymerase Rpb5, C-terminal domain
E PF03871 RNA_pol_Rpb5_N RNA polymerase Rpb5, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1340.10 Alpha Beta 3-Layer(aba) Sandwich Dna-directed Rna Polymerases I, Ii, And Iii 27 Kd Polypeptide; Chain: A; domain 1 RNA polymerase, Rpb5, N-terminal domain 4a3jE01
3.90.940.20 Alpha Beta Alpha-Beta Complex Eukaryotic RPB6 RNA polymerase subunit RPB5-like RNA polymerase subunit 4a3jE02
1I3QE 4AYBH 4A93E 5M5XE 3GTPE 4C3JE 3GTJE 4A3LE 4C3IE 3GTGE 5FLME 4A3FE 3CQZE 3HOYE 3HOXE 3I4NE 4Y52E 3M3YE 1TWHE 3HOUE 1R9TE 1TWAE 1TWGE 4BBRE 1Y1WE 5C44E 4Y7NE 4BXXE 5M3FE 3S17E 2WAQH 3PO2E 5IYBE 5IYDE 3S1QE 1TWFE 4A3KE 3S1ME 3S1RE 2YU9E 3HKZH 2R92E 3H0GE 4A3EE 1K83E 2JA8E 5IYCE 2JA5E 4BY1E 2NVXE 2PMZH 3GTOE 1DZFA 2E2JE 1I6HE 5C4XE 4A3ME 3PO3E 2R7ZE 3S2HE 5FJ8E 3M4OE 4A3GE 3HOVE 1TWCE 2Y0SH 5M5WE 1I50E 2E2HE 3GTME 3GTQE 2NVTE 2JA6E 5M3ME 1Y1VE 3I4ME 4A3IE 3RZDE 4A3BE 1WCME 1EIKA 4BBSE 3H3VF 5C3EE 4A3CE 4C2ME 5C4JE 4A3DE 2WB1H 4C3HE 2NVYE 3GTLE 3S1NE 4BY7E 4A3JE 5M5YE 2VUME 5IP9E 4X6AE 2NVQE 3S16E 3S2DE 2E2IE 4QIWH 5IP7E 2B63E 1SFOE 2JA7E 3S14E 3K7AE 3RZOE 3FKIE 3HOWE 3HOZE 3S15E 2R93E 3GTKE
chains in the Genus database with same CATH superfamily
1I3QE 2CW0E 4A3BF 4AYBH 4A93E 1I3QF 5M5XE 1I6VE 3GTPE 4Q4ZE 5M5XF 4C3JE 5C3EF 3GTPF 3GTJE 4A3LE 2WAQK 4C3JF 5C4JF 4A3CF 4C3IE 4C3HF 2NVYF 4XLNE 3GTGE 5FLME 4A3FE 3CQZE 4A3FF 1YNNK 4YFXE 3CQZF 3HOYE 5D4CE 5TMFE 4BY7F 3HOXE 3HKZK 5D4EE 2VUMF 3S16F 2E2IF 4OIQE 3I4NE 4Y52E 5D4DE 4OINE 3I4NF 3M3YE 1HQME 4KMUE 1SFOF 1TWHE 3HOUE 2JA7F 3S14F 1TWHF 4XSXE 3HOUF 1R9TE 3RZOF 3FKIF 1R9TF 1TWAE 4G7HE 1TWAF 1TWGE 4BBRE 2PMZK 1Y1WE 5E18E 3HOZF 3S15F 2R93F 5C44E 4Y7NE 4XSZE 1Y1WF 4BXXE 5C44F 4Y7NF 5M3FE 4BXXF 3S17E 5M3FF 4A93F 4GZYE 4KN4E 3GTJF 4A3LF 2O5JE 2WAQH 3PO2E 4C3IF 3PO2F 5IYBE 3GTGF 5FLMF 4LJZE 5IYDE 3S1QE 3EQLE 1TWFE 3HOYF 4A3KE 5IYDF 3S1QF 1TWFF 3HOXF 3S1ME 3S1RE 2YU9E 3HKZH 3S1MF 4Y52F 2O5IE 4X6AF 2A69E 3M3YF 2Y0SI 5E17E 2R92E 3H0GE 4A3EE 1K83E 2JA8E 5IYCE 2JA5E 3H0GF 1K83F 3WODE 4YFKE 5IYCF 2JA8F 4YG2E 5IPLE 4BY1E 1TWGF 4BBRF 1SMYE 2NVXE 4LLGE 2PMZH 3GTOE 1DZFA 2E2JE 3GTOF 1I6HE 2E2JF 3S17F 5C4XE 1I6HF 4A3ME 3PO3E 2R7ZE 3S2HE 3PO3F 2R7ZF 5FJ8E 4MEYE 3S2HF 3M4OE 4LK0E 4A3GE 3HOVE 4QIWK 3M4OF 4A3GF 2WB1I 1TWCE 4G7ZE 4MQ9E 2Y0SH 5IYBF 1TWCF 4KN7E 5M5WE 1I50E 2E2HE 3GTME 3GTQE 2NVTE 1I50F 4ZH4E 4JK1E 4A3KF 2E2HF 3GTMF 1YNJK 3GTQF 1ZYRE 2JA6E 3S1RF 5M3ME 4OIRE 1Y1VE 5BYHE 2YU9F 2JA6F 5M3MF 3I4ME 4A3IE 3RZDE 4AYBK 2A6EE 4A3BE 4A3IF 3RZDF 1WCME 2R92F 1QKLA 4A3EF 1EIKA 1WCMF 4OIPE 4BBSE 2JA5F 3H3VF 3DXJE 5C3EE 4A3CE 4BBSF 4C2ME 5C4JE 4A3DE 2WB1H 4C3HE 4BY1F 4C2MF 4A3DF 2NVYE 5TMCE 2NVXF 3GTLE 4XLPE 3GTLF 3S1NE 2KRXA 4G7OE 5C4XF 4A3MF 4BY7E 3S1NF 4A3JE 5M5YE 2VUME 2A6HE 5IP9E 4X6AE 5FJ8F 2NVQE 3S16E 3S2DE 2E2IE 5IP9F 5M5YF 4A3JF 2BE5E 2NVQF 3H3VG 3HOVF 4QIWH 3S2DF 5IP7E 2B63E 4OIOE 5IP7F 2B63F 5M5WF 1SFOE 2JA7E 2PPBE 2A68E 3S14E 3K7AE 1IW7E 3RZOE 2NVTF 3FKIE 3K7AF 3HOWE 4Q5SE 4YFNE 3HOWF 3HOZE 3S15E 2R93E 1Y1VF 3GTKE 4MEXE 3GTKF 3I4MF 4LK1E
chains in the Genus database with same CATH topology
1I3QE 4AYBH 4A93E 5M5XE 3GTPE 4C3JE 3GTJE 4A3LE 4C3IE 3GTGE 5FLME 4A3FE 3CQZE 3HOYE 3HOXE 3I4NE 4Y52E 3M3YE 1TWHE 3HOUE 1R9TE 1TWAE 1TWGE 4BBRE 1Y1WE 5C44E 4Y7NE 4BXXE 5M3FE 3S17E 2WAQH 3PO2E 5IYBE 5IYDE 3S1QE 1TWFE 4A3KE 3S1ME 3S1RE 2YU9E 3HKZH 2R92E 3H0GE 4A3EE 1K83E 2JA8E 5IYCE 2JA5E 4BY1E 2NVXE 2PMZH 3GTOE 1DZFA 2E2JE 1I6HE 5C4XE 4A3ME 3PO3E 2R7ZE 3S2HE 5FJ8E 3M4OE 4A3GE 3HOVE 1TWCE 2Y0SH 5M5WE 1I50E 2E2HE 3GTME 3GTQE 2NVTE 2JA6E 5M3ME 1Y1VE 3I4ME 4A3IE 3RZDE 4A3BE 1WCME 1EIKA 4BBSE 3H3VF 5C3EE 4A3CE 4C2ME 5C4JE 4A3DE 2WB1H 4C3HE 2NVYE 3GTLE 3S1NE 4BY7E 4A3JE 5M5YE 2VUME 5IP9E 4X6AE 2NVQE 3S16E 3S2DE 2E2IE 4QIWH 5IP7E 2B63E 1SFOE 2JA7E 3S14E 3K7AE 3RZOE 3FKIE 3HOWE 3HOZE 3S15E 2R93E 3GTKE
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1I3Q E;  4AYB H;  4A93 E;  5M5X E;  3GTP E;  4C3J E;  3GTJ E;  4A3L E;  4C3I E;  3GTG E;  5FLM E;  4A3F E;  3CQZ E;  3HOY E;  3HOX E;  3I4N E;  4Y52 E;  3M3Y E;  1TWH E;  3HOU E;  1R9T E;  1TWA E;  1TWG E;  4BBR E;  1Y1W E;  5C44 E;  4Y7N E;  4BXX E;  5M3F E;  3S17 E;  2WAQ H;  3PO2 E;  5IYB E;  5IYD E;  3S1Q E;  1TWF E;  4A3K E;  3S1M E;  3S1R E;  2YU9 E;  3HKZ H;  2R92 E;  3H0G E;  4A3E E;  1K83 E;  2JA8 E;  5IYC E;  2JA5 E;  4BY1 E;  2NVX E;  2PMZ H;  3GTO E;  1DZF A;  2E2J E;  1I6H E;  5C4X E;  4A3M E;  3PO3 E;  2R7Z E;  3S2H E;  5FJ8 E;  3M4O E;  4A3G E;  3HOV E;  1TWC E;  2Y0S H;  5M5W E;  1I50 E;  2E2H E;  3GTM E;  3GTQ E;  2NVT E;  2JA6 E;  5M3M E;  1Y1V E;  3I4M E;  4A3I E;  3RZD E;  4A3B E;  1WCM E;  1EIK A;  4BBS E;  3H3V F;  5C3E E;  4A3C E;  4C2M E;  5C4J E;  4A3D E;  2WB1 H;  4C3H E;  2NVY E;  3GTL E;  3S1N E;  4BY7 E;  4A3J E;  5M5Y E;  2VUM E;  5IP9 E;  4X6A E;  2NVQ E;  3S16 E;  3S2D E;  2E2I E;  4QIW H;  5IP7 E;  2B63 E;  1SFO E;  2JA7 E;  3S14 E;  3K7A E;  3RZO E;  3FKI E;  3HOW E;  3HOZ E;  3S15 E;  2R93 E;  3GTK E; 
#chains in the Genus database with same CATH topology
 1I3Q E;  2CW0 E;  4A3B F;  4AYB H;  4A93 E;  1I3Q F;  5M5X E;  1I6V E;  3GTP E;  4Q4Z E;  5M5X F;  4C3J E;  5C3E F;  3GTP F;  3GTJ E;  4A3L E;  2WAQ K;  4C3J F;  5C4J F;  4A3C F;  4C3I E;  4C3H F;  2NVY F;  4XLN E;  3GTG E;  5FLM E;  4A3F E;  3CQZ E;  4A3F F;  1YNN K;  4YFX E;  3CQZ F;  3HOY E;  5D4C E;  5TMF E;  4BY7 F;  3HOX E;  3HKZ K;  5D4E E;  2VUM F;  3S16 F;  2E2I F;  4OIQ E;  3I4N E;  4Y52 E;  5D4D E;  4OIN E;  3I4N F;  3M3Y E;  1HQM E;  4KMU E;  1SFO F;  1TWH E;  3HOU E;  2JA7 F;  3S14 F;  1TWH F;  4XSX E;  3HOU F;  1R9T E;  3RZO F;  3FKI F;  1R9T F;  1TWA E;  4G7H E;  1TWA F;  1TWG E;  4BBR E;  2PMZ K;  1Y1W E;  5E18 E;  3HOZ F;  3S15 F;  2R93 F;  5C44 E;  4Y7N E;  4XSZ E;  1Y1W F;  4BXX E;  5C44 F;  4Y7N F;  5M3F E;  4BXX F;  3S17 E;  5M3F F;  4A93 F;  4GZY E;  4KN4 E;  3GTJ F;  4A3L F;  2O5J E;  2WAQ H;  3PO2 E;  4C3I F;  3PO2 F;  5IYB E;  3GTG F;  5FLM F;  4LJZ E;  5IYD E;  3S1Q E;  3EQL E;  1TWF E;  3HOY F;  4A3K E;  5IYD F;  3S1Q F;  1TWF F;  3HOX F;  3S1M E;  3S1R E;  2YU9 E;  3HKZ H;  3S1M F;  4Y52 F;  2O5I E;  4X6A F;  2A69 E;  3M3Y F;  2Y0S I;  5E17 E;  2R92 E;  3H0G E;  4A3E E;  1K83 E;  2JA8 E;  5IYC E;  2JA5 E;  3H0G F;  1K83 F;  3WOD E;  4YFK E;  5IYC F;  2JA8 F;  4YG2 E;  5IPL E;  4BY1 E;  1TWG F;  4BBR F;  1SMY E;  2NVX E;  4LLG E;  2PMZ H;  3GTO E;  1DZF A;  2E2J E;  3GTO F;  1I6H E;  2E2J F;  3S17 F;  5C4X E;  1I6H F;  4A3M E;  3PO3 E;  2R7Z E;  3S2H E;  3PO3 F;  2R7Z F;  5FJ8 E;  4MEY E;  3S2H F;  3M4O E;  4LK0 E;  4A3G E;  3HOV E;  4QIW K;  3M4O F;  4A3G F;  2WB1 I;  1TWC E;  4G7Z E;  4MQ9 E;  2Y0S H;  5IYB F;  1TWC F;  4KN7 E;  5M5W E;  1I50 E;  2E2H E;  3GTM E;  3GTQ E;  2NVT E;  1I50 F;  4ZH4 E;  4JK1 E;  4A3K F;  2E2H F;  3GTM F;  1YNJ K;  3GTQ F;  1ZYR E;  2JA6 E;  3S1R F;  5M3M E;  4OIR E;  1Y1V E;  5BYH E;  2YU9 F;  2JA6 F;  5M3M F;  3I4M E;  4A3I E;  3RZD E;  4AYB K;  2A6E E;  4A3B E;  4A3I F;  3RZD F;  1WCM E;  2R92 F;  1QKL A;  4A3E F;  1EIK A;  1WCM F;  4OIP E;  4BBS E;  2JA5 F;  3H3V F;  3DXJ E;  5C3E E;  4A3C E;  4BBS F;  4C2M E;  5C4J E;  4A3D E;  2WB1 H;  4C3H E;  4BY1 F;  4C2M F;  4A3D F;  2NVY E;  5TMC E;  2NVX F;  3GTL E;  4XLP E;  3GTL F;  3S1N E;  2KRX A;  4G7O E;  5C4X F;  4A3M F;  4BY7 E;  3S1N F;  4A3J E;  5M5Y E;  2VUM E;  2A6H E;  5IP9 E;  4X6A E;  5FJ8 F;  2NVQ E;  3S16 E;  3S2D E;  2E2I E;  5IP9 F;  5M5Y F;  4A3J F;  2BE5 E;  2NVQ F;  3H3V G;  3HOV F;  4QIW H;  3S2D F;  5IP7 E;  2B63 E;  4OIO E;  5IP7 F;  2B63 F;  5M5W F;  1SFO E;  2JA7 E;  2PPB E;  2A68 E;  3S14 E;  3K7A E;  1IW7 E;  3RZO E;  2NVT F;  3FKI E;  3K7A F;  3HOW E;  4Q5S E;  4YFN E;  3HOW F;  3HOZ E;  3S15 E;  2R93 E;  1Y1V F;  3GTK E;  4MEX E;  3GTK F;  3I4M F;  4LK1 E; 
#chains in the Genus database with same CATH homology
 1I3Q E;  4AYB H;  4A93 E;  5M5X E;  3GTP E;  4C3J E;  3GTJ E;  4A3L E;  4C3I E;  3GTG E;  5FLM E;  4A3F E;  3CQZ E;  3HOY E;  3HOX E;  3I4N E;  4Y52 E;  3M3Y E;  1TWH E;  3HOU E;  1R9T E;  1TWA E;  1TWG E;  4BBR E;  1Y1W E;  5C44 E;  4Y7N E;  4BXX E;  5M3F E;  3S17 E;  2WAQ H;  3PO2 E;  5IYB E;  5IYD E;  3S1Q E;  1TWF E;  4A3K E;  3S1M E;  3S1R E;  2YU9 E;  3HKZ H;  2R92 E;  3H0G E;  4A3E E;  1K83 E;  2JA8 E;  5IYC E;  2JA5 E;  4BY1 E;  2NVX E;  2PMZ H;  3GTO E;  1DZF A;  2E2J E;  1I6H E;  5C4X E;  4A3M E;  3PO3 E;  2R7Z E;  3S2H E;  5FJ8 E;  3M4O E;  4A3G E;  3HOV E;  1TWC E;  2Y0S H;  5M5W E;  1I50 E;  2E2H E;  3GTM E;  3GTQ E;  2NVT E;  2JA6 E;  5M3M E;  1Y1V E;  3I4M E;  4A3I E;  3RZD E;  4A3B E;  1WCM E;  1EIK A;  4BBS E;  3H3V F;  5C3E E;  4A3C E;  4C2M E;  5C4J E;  4A3D E;  2WB1 H;  4C3H E;  2NVY E;  3GTL E;  3S1N E;  4BY7 E;  4A3J E;  5M5Y E;  2VUM E;  5IP9 E;  4X6A E;  2NVQ E;  3S16 E;  3S2D E;  2E2I E;  4QIW H;  5IP7 E;  2B63 E;  1SFO E;  2JA7 E;  3S14 E;  3K7A E;  3RZO E;  3FKI E;  3HOW E;  3HOZ E;  3S15 E;  2R93 E;  3GTK E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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