4A3LE

Rna polymerase ii initial transcribing complex with a 7nt dna-rna hybrid and soaked with ampcpp
Total Genus 62
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
62
sequence length
214
structure length
214
Chain Sequence
DQENERNISRLWRAFRTVKEMVKDRGYFITQEEVELPLEDFKAKYCDSMGRPQRKMMSFQANPTEESISKFPDMGSLWVEFCDEPSVGVKTMKTFVIHIQEKNFQTGIFVYQNNITPSAMKLVPSIPPATIETFNEAALVVNITHHELVPKHIRLSSDEKRELLKRYRLKESQLPRIQRADPVALYLGLKRGEVVKIIRKSETSGRYASYRICM
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Structural basis of initial RNA polymerase II transcription.
pubmed doi rcsb
molecule tags Transcription
molecule keywords DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1
total genus 62
structure length 214
sequence length 214
ec nomenclature
pdb deposition date 2011-09-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF01191 RNA_pol_Rpb5_C RNA polymerase Rpb5, C-terminal domain
E PF03871 RNA_pol_Rpb5_N RNA polymerase Rpb5, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1340.10 Alpha Beta 3-Layer(aba) Sandwich Dna-directed Rna Polymerases I, Ii, And Iii 27 Kd Polypeptide; Chain: A; domain 1 RNA polymerase, Rpb5, N-terminal domain 4a3lE01
3.90.940.20 Alpha Beta Alpha-Beta Complex Eukaryotic RPB6 RNA polymerase subunit RPB5-like RNA polymerase subunit 4a3lE02
3S1RE 3PO2E 1I6HE 4A3CE 2NVXE 5IYCE 5C3EE 4BXXE 3HOWE 4A3JE 1EIKA 4A3ME 4Y52E 5M5WE 4C3HE 3GTQE 2JA6E 3HOXE 2JA7E 1I50E 4X6AE 1WCME 4C3IE 4A93E 3H0GE 5M3ME 5IYBE 1I3QE 4QIWH 4A3BE 2VUME 1TWHE 4C2ME 3S1ME 5C44E 2NVQE 2WB1H 1TWFE 5M3FE 3HKZH 5IP7E 4A3KE 4BY1E 2B63E 2NVTE 5M5XE 3H3VF 3GTME 1Y1VE 4A3IE 4Y7NE 3GTGE 2E2JE 2R92E 5C4XE 4A3EE 4BBSE 2JA5E 3HOYE 2JA8E 3S15E 5FLME 1Y1WE 4A3DE 2R93E 4A3LE 3S16E 5IYDE 3GTOE 4A3GE 3GTJE 3M3YE 5C4JE 4A3FE 5IP9E 3S17E 1TWAE 4BY7E 3FKIE 2Y0SH 5FJ8E 5M5YE 3S2HE 3I4NE 3M4OE 3K7AE 1DZFA 1K83E 3S1NE 2E2HE 3RZDE 4AYBH 3GTPE 2PMZH 4BBRE 1SFOE 4C3JE 3HOUE 1TWCE 3CQZE 3HOZE 2NVYE 3GTLE 3I4ME 3S14E 2E2IE 3PO3E 3HOVE 3RZOE 2WAQH 3S1QE 1R9TE 2YU9E 3GTKE 1TWGE 3S2DE 2R7ZE
chains in the Genus database with same CATH superfamily
3GTGF 2R92F 4X6AF 1WCMF 4C3IF 4A93F 1ZYRE 3H0GF 5M3MF 5IYBF 4KN4E 4OIQE 4A3BF 3S1RE 3PO2E 1I6HE 1IW7E 4YFNE 2VUMF 4A3CE 4YFKE 4MEXE 3S1MF 2NVXE 5E18E 5IYCE 5C3EE 4BXXE 4XLNE 5C44F 1HQME 2NVQF 3HOWE 4MQ9E 4OINE 1SMYE 1TWFF 3GTOF 4A3JE 1EIKA 5M3FF 4A3ME 4Y52E 3WODE 3M3YF 5IP7F 4A3KF 4BY1F 2B63F 5M5WE 2NVTF 4C3HE 5M5XF 3GTQE 4LLGE 2JA6E 3HOXE 2JA7E 1YNNK 3GTMF 1Y1VF 2WB1I 1I50E 4X6AE 1WCME 3DXJE 4C3IE 4A93E 3H0GE 4KN7E 5M3ME 5IYBE 5FJ8F 4A3IF 3I4NF 4GZYE 1I3QE 4Y7NF 4YG2E 4QIWH 4A3BE 2E2JF 5C4XF 2VUME 1TWHE 4A3EF 4C2ME 3S1ME 4BBSF 3GTPF 5C44E 2NVQE 2JA5F 4LK0E 4JK1E 3HOYF 2WB1H 2JA8F 4BBRF 3S15F 1TWFE 2Y0SI 5FLMF 1Y1WF 5TMCE 3CQZF 5M3FE 4AYBK 3HKZH 4A3DF 2R93F 5IP7E 2NVYF 4A3KE 4A3LF 4BY1E 2B63E 3S16F 2NVTE 2PMZK 5IYDF 4LK1E 4A3GF 5M5XE 3H3VF 3S14F 5IPLE 3GTJF 3GTME 5C4JF 4A3FF 4MEYE 1Y1VE 3S1QF 4XSXE 4A3IE 5IP9F 4ZH4E 4OIRE 2CW0E 3GTKF 3S17F 4Y7NE 2A6EE 3GTGE 1TWAF 4XSZE 3FKIF 2WAQK 2E2JE 2R92E 5C4XE 4BY7F 3H3VG 4A3EE 5M5YF 4BBSE 3S2HF 3M4OF 2O5JE 2JA5E 3HOYE 3K7AF 2JA8E 3S15E 4YFXE 1K83F 3S1NF 2E2HF 5FLME 1Y1WE 3RZDF 2PPBE 4A3DE 1I6VE 2R93E 2A68E 4A3LE 2A6HE 4XLPE 3S16E 1SFOF 5IYDE 3GTOE 4A3GE 5TMFE 4C3JF 3HOUF 1TWCF 3GTJE 3M3YE 5C4JE 4A3FE 4KMUE 3HOZF 3GTLF 4OIPE 3I4MF 5D4EE 1QKLA 4G7ZE 5D4DE 2E2IF 3PO3F 5M5WF 5IP9E 3S17E 4LJZE 3HOVF 3RZOF 4Q4ZE 1TWAE 4BY7E 3FKIE 1R9TF 2Y0SH 2YU9F 5FJ8E 5M5YE 3S2HE 3I4NE 3M4OE 1TWGF 3K7AE 3S2DF 1DZFA 2O5IE 3EQLE 1K83E 3S1NE 2R7ZF 2E2HE 1I3QF 2BE5E 3RZDE 4AYBH 3GTPE 2A69E 1TWHF 2PMZH 4BBRE 4C2MF 1SFOE 4C3JE 3HOUE 1TWCE 3CQZE 3S1RF 4QIWK 3PO2F 1I6HF 3HOZE 2NVYE 5D4CE 3GTLE 4A3CF 3I4ME 2NVXF 5IYCF 5C3EF 4G7HE 3S14E 4BXXF 3HOWF 2E2IE 1YNJK 2KRXA 3PO3E 4A3JF 3HOVE 3RZOE 4OIOE 4A3MF 4Y52F 2WAQH 3HKZK 5E17E 3S1QE 1R9TE 2YU9E 3GTKE 4C3HF 4G7OE 3GTQF 2JA6F 3HOXF 2JA7F 4Q5SE 1TWGE 3S2DE 5BYHE 2R7ZE 1I50F
chains in the Genus database with same CATH topology
3S1RE 3PO2E 1I6HE 4A3CE 2NVXE 5IYCE 5C3EE 4BXXE 3HOWE 4A3JE 1EIKA 4A3ME 4Y52E 5M5WE 4C3HE 3GTQE 2JA6E 3HOXE 2JA7E 1I50E 4X6AE 1WCME 4C3IE 4A93E 3H0GE 5M3ME 5IYBE 1I3QE 4QIWH 4A3BE 2VUME 1TWHE 4C2ME 3S1ME 5C44E 2NVQE 2WB1H 1TWFE 5M3FE 3HKZH 5IP7E 4A3KE 4BY1E 2B63E 2NVTE 5M5XE 3H3VF 3GTME 1Y1VE 4A3IE 4Y7NE 3GTGE 2E2JE 2R92E 5C4XE 4A3EE 4BBSE 2JA5E 3HOYE 2JA8E 3S15E 5FLME 1Y1WE 4A3DE 2R93E 4A3LE 3S16E 5IYDE 3GTOE 4A3GE 3GTJE 3M3YE 5C4JE 4A3FE 5IP9E 3S17E 1TWAE 4BY7E 3FKIE 2Y0SH 5FJ8E 5M5YE 3S2HE 3I4NE 3M4OE 3K7AE 1DZFA 1K83E 3S1NE 2E2HE 3RZDE 4AYBH 3GTPE 2PMZH 4BBRE 1SFOE 4C3JE 3HOUE 1TWCE 3CQZE 3HOZE 2NVYE 3GTLE 3I4ME 3S14E 2E2IE 3PO3E 3HOVE 3RZOE 2WAQH 3S1QE 1R9TE 2YU9E 3GTKE 1TWGE 3S2DE 2R7ZE
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3S1R E;  3PO2 E;  1I6H E;  4A3C E;  2NVX E;  5IYC E;  5C3E E;  4BXX E;  3HOW E;  4A3J E;  1EIK A;  4A3M E;  4Y52 E;  5M5W E;  4C3H E;  3GTQ E;  2JA6 E;  3HOX E;  2JA7 E;  1I50 E;  4X6A E;  1WCM E;  4C3I E;  4A93 E;  3H0G E;  5M3M E;  5IYB E;  1I3Q E;  4QIW H;  4A3B E;  2VUM E;  1TWH E;  4C2M E;  3S1M E;  5C44 E;  2NVQ E;  2WB1 H;  1TWF E;  5M3F E;  3HKZ H;  5IP7 E;  4A3K E;  4BY1 E;  2B63 E;  2NVT E;  5M5X E;  3H3V F;  3GTM E;  1Y1V E;  4A3I E;  4Y7N E;  3GTG E;  2E2J E;  2R92 E;  5C4X E;  4A3E E;  4BBS E;  2JA5 E;  3HOY E;  2JA8 E;  3S15 E;  5FLM E;  1Y1W E;  4A3D E;  2R93 E;  4A3L E;  3S16 E;  5IYD E;  3GTO E;  4A3G E;  3GTJ E;  3M3Y E;  5C4J E;  4A3F E;  5IP9 E;  3S17 E;  1TWA E;  4BY7 E;  3FKI E;  2Y0S H;  5FJ8 E;  5M5Y E;  3S2H E;  3I4N E;  3M4O E;  3K7A E;  1DZF A;  1K83 E;  3S1N E;  2E2H E;  3RZD E;  4AYB H;  3GTP E;  2PMZ H;  4BBR E;  1SFO E;  4C3J E;  3HOU E;  1TWC E;  3CQZ E;  3HOZ E;  2NVY E;  3GTL E;  3I4M E;  3S14 E;  2E2I E;  3PO3 E;  3HOV E;  3RZO E;  2WAQ H;  3S1Q E;  1R9T E;  2YU9 E;  3GTK E;  1TWG E;  3S2D E;  2R7Z E; 
#chains in the Genus database with same CATH topology
 3GTG F;  2R92 F;  4X6A F;  1WCM F;  4C3I F;  4A93 F;  1ZYR E;  3H0G F;  5M3M F;  5IYB F;  4KN4 E;  4OIQ E;  4A3B F;  3S1R E;  3PO2 E;  1I6H E;  1IW7 E;  4YFN E;  2VUM F;  4A3C E;  4YFK E;  4MEX E;  3S1M F;  2NVX E;  5E18 E;  5IYC E;  5C3E E;  4BXX E;  4XLN E;  5C44 F;  1HQM E;  2NVQ F;  3HOW E;  4MQ9 E;  4OIN E;  1SMY E;  1TWF F;  3GTO F;  4A3J E;  1EIK A;  5M3F F;  4A3M E;  4Y52 E;  3WOD E;  3M3Y F;  5IP7 F;  4A3K F;  4BY1 F;  2B63 F;  5M5W E;  2NVT F;  4C3H E;  5M5X F;  3GTQ E;  4LLG E;  2JA6 E;  3HOX E;  2JA7 E;  1YNN K;  3GTM F;  1Y1V F;  2WB1 I;  1I50 E;  4X6A E;  1WCM E;  3DXJ E;  4C3I E;  4A93 E;  3H0G E;  4KN7 E;  5M3M E;  5IYB E;  5FJ8 F;  4A3I F;  3I4N F;  4GZY E;  1I3Q E;  4Y7N F;  4YG2 E;  4QIW H;  4A3B E;  2E2J F;  5C4X F;  2VUM E;  1TWH E;  4A3E F;  4C2M E;  3S1M E;  4BBS F;  3GTP F;  5C44 E;  2NVQ E;  2JA5 F;  4LK0 E;  4JK1 E;  3HOY F;  2WB1 H;  2JA8 F;  4BBR F;  3S15 F;  1TWF E;  2Y0S I;  5FLM F;  1Y1W F;  5TMC E;  3CQZ F;  5M3F E;  4AYB K;  3HKZ H;  4A3D F;  2R93 F;  5IP7 E;  2NVY F;  4A3K E;  4A3L F;  4BY1 E;  2B63 E;  3S16 F;  2NVT E;  2PMZ K;  5IYD F;  4LK1 E;  4A3G F;  5M5X E;  3H3V F;  3S14 F;  5IPL E;  3GTJ F;  3GTM E;  5C4J F;  4A3F F;  4MEY E;  1Y1V E;  3S1Q F;  4XSX E;  4A3I E;  5IP9 F;  4ZH4 E;  4OIR E;  2CW0 E;  3GTK F;  3S17 F;  4Y7N E;  2A6E E;  3GTG E;  1TWA F;  4XSZ E;  3FKI F;  2WAQ K;  2E2J E;  2R92 E;  5C4X E;  4BY7 F;  3H3V G;  4A3E E;  5M5Y F;  4BBS E;  3S2H F;  3M4O F;  2O5J E;  2JA5 E;  3HOY E;  3K7A F;  2JA8 E;  3S15 E;  4YFX E;  1K83 F;  3S1N F;  2E2H F;  5FLM E;  1Y1W E;  3RZD F;  2PPB E;  4A3D E;  1I6V E;  2R93 E;  2A68 E;  4A3L E;  2A6H E;  4XLP E;  3S16 E;  1SFO F;  5IYD E;  3GTO E;  4A3G E;  5TMF E;  4C3J F;  3HOU F;  1TWC F;  3GTJ E;  3M3Y E;  5C4J E;  4A3F E;  4KMU E;  3HOZ F;  3GTL F;  4OIP E;  3I4M F;  5D4E E;  1QKL A;  4G7Z E;  5D4D E;  2E2I F;  3PO3 F;  5M5W F;  5IP9 E;  3S17 E;  4LJZ E;  3HOV F;  3RZO F;  4Q4Z E;  1TWA E;  4BY7 E;  3FKI E;  1R9T F;  2Y0S H;  2YU9 F;  5FJ8 E;  5M5Y E;  3S2H E;  3I4N E;  3M4O E;  1TWG F;  3K7A E;  3S2D F;  1DZF A;  2O5I E;  3EQL E;  1K83 E;  3S1N E;  2R7Z F;  2E2H E;  1I3Q F;  2BE5 E;  3RZD E;  4AYB H;  3GTP E;  2A69 E;  1TWH F;  2PMZ H;  4BBR E;  4C2M F;  1SFO E;  4C3J E;  3HOU E;  1TWC E;  3CQZ E;  3S1R F;  4QIW K;  3PO2 F;  1I6H F;  3HOZ E;  2NVY E;  5D4C E;  3GTL E;  4A3C F;  3I4M E;  2NVX F;  5IYC F;  5C3E F;  4G7H E;  3S14 E;  4BXX F;  3HOW F;  2E2I E;  1YNJ K;  2KRX A;  3PO3 E;  4A3J F;  3HOV E;  3RZO E;  4OIO E;  4A3M F;  4Y52 F;  2WAQ H;  3HKZ K;  5E17 E;  3S1Q E;  1R9T E;  2YU9 E;  3GTK E;  4C3H F;  4G7O E;  3GTQ F;  2JA6 F;  3HOX F;  2JA7 F;  4Q5S E;  1TWG E;  3S2D E;  5BYH E;  2R7Z E;  1I50 F; 
#chains in the Genus database with same CATH homology
 3S1R E;  3PO2 E;  1I6H E;  4A3C E;  2NVX E;  5IYC E;  5C3E E;  4BXX E;  3HOW E;  4A3J E;  1EIK A;  4A3M E;  4Y52 E;  5M5W E;  4C3H E;  3GTQ E;  2JA6 E;  3HOX E;  2JA7 E;  1I50 E;  4X6A E;  1WCM E;  4C3I E;  4A93 E;  3H0G E;  5M3M E;  5IYB E;  1I3Q E;  4QIW H;  4A3B E;  2VUM E;  1TWH E;  4C2M E;  3S1M E;  5C44 E;  2NVQ E;  2WB1 H;  1TWF E;  5M3F E;  3HKZ H;  5IP7 E;  4A3K E;  4BY1 E;  2B63 E;  2NVT E;  5M5X E;  3H3V F;  3GTM E;  1Y1V E;  4A3I E;  4Y7N E;  3GTG E;  2E2J E;  2R92 E;  5C4X E;  4A3E E;  4BBS E;  2JA5 E;  3HOY E;  2JA8 E;  3S15 E;  5FLM E;  1Y1W E;  4A3D E;  2R93 E;  4A3L E;  3S16 E;  5IYD E;  3GTO E;  4A3G E;  3GTJ E;  3M3Y E;  5C4J E;  4A3F E;  5IP9 E;  3S17 E;  1TWA E;  4BY7 E;  3FKI E;  2Y0S H;  5FJ8 E;  5M5Y E;  3S2H E;  3I4N E;  3M4O E;  3K7A E;  1DZF A;  1K83 E;  3S1N E;  2E2H E;  3RZD E;  4AYB H;  3GTP E;  2PMZ H;  4BBR E;  1SFO E;  4C3J E;  3HOU E;  1TWC E;  3CQZ E;  3HOZ E;  2NVY E;  3GTL E;  3I4M E;  3S14 E;  2E2I E;  3PO3 E;  3HOV E;  3RZO E;  2WAQ H;  3S1Q E;  1R9T E;  2YU9 E;  3GTK E;  1TWG E;  3S2D E;  2R7Z E; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...