4A93E

Rna polymerase ii elongation complex containing a cpd lesion
Total Genus 62
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
62
sequence length
214
structure length
214
Chain Sequence
DQENERNISRLWRAFRTVKEMVKDRGYFITQEEVELPLEDFKAKYCDSMGRPQRKMMSFQANPTEESISKFPDMGSLWVEFCDEPSVGVKTMKTFVIHIQEKNFQTGIFVYQNNITPSAMKLVPSIPPATIETFNEAALVVNITHHELVPKHIRLSSDEKRELLKRYRLKESQLPRIQRADPVALYLGLKRGEVVKIIRKSETSGRYASYRICM
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mechanism of Translesion Transcription by RNA Polymerase II and its Role in Cellular Resistance to DNA Damage.
pubmed doi rcsb
molecule tags Transcription
molecule keywords DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1
total genus 62
structure length 214
sequence length 214
ec nomenclature
pdb deposition date 2011-11-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF01191 RNA_pol_Rpb5_C RNA polymerase Rpb5, C-terminal domain
E PF03871 RNA_pol_Rpb5_N RNA polymerase Rpb5, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1340.10 Alpha Beta 3-Layer(aba) Sandwich Dna-directed Rna Polymerases I, Ii, And Iii 27 Kd Polypeptide; Chain: A; domain 1 RNA polymerase, Rpb5, N-terminal domain 4a93E01
3.90.940.20 Alpha Beta Alpha-Beta Complex Eukaryotic RPB6 RNA polymerase subunit RPB5-like RNA polymerase subunit 4a93E02
5IP9E 3S1QE 4A3DE 5FLME 2NVYE 3PO3E 5IYCE 4BBRE 4A3FE 2JA6E 2E2HE 3S1NE 2E2IE 5FJ8E 1TWGE 3M4OE 3HOUE 2R7ZE 1I3QE 4C3JE 3S1RE 3I4NE 4A3BE 3RZOE 3I4ME 2R93E 4BY1E 4A3KE 3H0GE 3CQZE 3HOVE 3K7AE 3PO2E 4A3IE 3HOYE 4C3IE 1R9TE 5C44E 3HKZH 1WCME 3S2DE 4A3LE 4A3GE 1TWHE 5C4XE 4A3ME 2JA8E 3S2HE 4A3CE 2WB1H 3HOZE 1K83E 5M3ME 5M5YE 4A93E 3GTME 5M5XE 4C2ME 2R92E 5IYBE 2VUME 1SFOE 2E2JE 3GTGE 3HOXE 1TWFE 3M3YE 3GTLE 2NVXE 5M5WE 3GTQE 1Y1VE 4BBSE 5C3EE 4AYBH 4BY7E 4Y52E 1EIKA 3GTJE 1TWCE 3GTPE 3S1ME 5IYDE 5C4JE 3S16E 2B63E 4QIWH 3S15E 2Y0SH 4C3HE 3FKIE 3S17E 3HOWE 1TWAE 2NVQE 3GTOE 2YU9E 1I6HE 2WAQH 4A3EE 3RZDE 2JA5E 2NVTE 5IP7E 4A3JE 1DZFA 5M3FE 4Y7NE 3GTKE 2JA7E 4X6AE 2PMZH 3H3VF 1I50E 3S14E 4BXXE 1Y1WE
chains in the Genus database with same CATH superfamily
4C3HF 5IP9E 3S1QE 1YNNK 4OIPE 2A68E 4A3DE 3FKIF 5FLME 4OIQE 3S17F 2NVYE 3HOWF 3PO3E 5IYCE 1TWAF 3H3VG 4BBRE 4A3FE 2JA6E 2E2HE 4LK0E 3S1NE 2E2IE 2NVQF 5FJ8E 1TWGE 4Q5SE 3EQLE 4YFXE 3M4OE 2WB1I 3GTOF 3HOUE 2R7ZE 2YU9F 1I3QE 4AYBK 1I6HF 4C3JE 3S1RE 3I4NE 4A3BE 5BYHE 4A3EF 3RZDF 2JA5F 2NVTF 5IP7F 4A3JF 3RZOE 3I4ME 2R93E 5M3FF 4BY1E 4A3KE 3H0GE 4Y7NF 3CQZE 3GTKF 3HOVE 3K7AE 3PO2E 4A3IE 3HOYE 4Q4ZE 4C3IE 2JA7F 1R9TE 4X6AF 5C44E 3HKZH 1WCME 3S2DE 4A3LE 4A3GE 1TWHE 1I50F 1Y1WF 3S14F 4BXXF 4A3CF 5C4XE 5IP9F 4YFNE 4A3ME 2JA8E 3S2HE 3S1QF 4A3DF 5FLMF 2NVYF 3PO3F 5IYCF 2CW0E 4A3CE 2WB1H 4BBRF 4QIWK 3HOZE 4A3FF 2JA6F 2E2HF 3S1NF 1K83E 2E2IF 4YFKE 5M3ME 4MEYE 1TWGF 5FJ8F 5M5YE 4A93E 3GTME 4G7OE 5M5XE 4C2ME 2R92E 2A69E 3HOUF 5IYBE 2R7ZF 1I3QF 2VUME 3M4OF 1SFOE 2E2JE 1I6VE 4C3JF 3GTGE 3S1RF 3HOXE 3I4NF 4A3BF 1TWFE 4YG2E 3M3YF 5D4DE 3I4MF 3RZOF 2PPBE 2R93F 4BY1F 4A3KF 5TMCE 4XLNE 3H0GF 3M3YE 3CQZF 2A6EE 3HOVF 3GTLE 2NVXE 3K7AF 3PO2F 4A3IF 3HOYF 4C3IF 1R9TF 2WAQK 5M5WE 5C44F 3GTQE 1Y1VE 4BBSE 1QKLA 1TWHF 1WCMF 4LK1E 2O5IE 3S2DF 4A3LF 4A3GF 5C4XF 4MEXE 4A3MF 2JA8F 5C3EE 4AYBH 3S2HF 1SMYE 4OINE 2Y0SI 3WODE 3HOZF 4BY7E 3HKZK 1K83F 3DXJE 5M3MF 2PMZK 4Y52E 5M5YF 4A93F 3GTMF 5M5XF 4C2MF 2R92F 1EIKA 4ZH4E 5IYBF 5D4EE 2VUMF 1SFOF 2E2JF 3GTJE 5E17E 3GTGF 3HOXF 4KMUE 1TWFF 1IW7E 1TWCE 4GZYE 3GTPE 1ZYRE 3S1ME 5IYDE 5C4JE 4OIOE 3S16E 1HQME 2B63E 4QIWH 2NVXF 3S15E 3GTLF 5IPLE 5M5WF 2Y0SH 1Y1VF 1YNJK 3GTQF 4BBSF 4KN7E 4XSXE 4C3HE 5C3EF 4XLPE 4MQ9E 3FKIE 3S17E 3HOWE 1TWAE 5E18E 4BY7F 4LLGE 4OIRE 2O5JE 2NVQE 4Y52F 2A6HE 3GTOE 4G7HE 2YU9E 1I6HE 2WAQH 3GTJF 4A3EE 3RZDE 2JA5E 2KRXA 2BE5E 1TWCF 2NVTE 5D4CE 5IP7E 4A3JE 3GTPF 1DZFA 3S1MF 5M3FE 4JK1E 4XSZE 5IYDF 5C4JF 4Y7NE 3S16F 2B63F 3GTKE 3S15F 5TMFE 4KN4E 4LJZE 4G7ZE 2JA7E 4X6AE 2PMZH 3H3VF 1I50E 3S14E 4BXXE 1Y1WE
chains in the Genus database with same CATH topology
5IP9E 3S1QE 4A3DE 5FLME 2NVYE 3PO3E 5IYCE 4BBRE 4A3FE 2JA6E 2E2HE 3S1NE 2E2IE 5FJ8E 1TWGE 3M4OE 3HOUE 2R7ZE 1I3QE 4C3JE 3S1RE 3I4NE 4A3BE 3RZOE 3I4ME 2R93E 4BY1E 4A3KE 3H0GE 3CQZE 3HOVE 3K7AE 3PO2E 4A3IE 3HOYE 4C3IE 1R9TE 5C44E 3HKZH 1WCME 3S2DE 4A3LE 4A3GE 1TWHE 5C4XE 4A3ME 2JA8E 3S2HE 4A3CE 2WB1H 3HOZE 1K83E 5M3ME 5M5YE 4A93E 3GTME 5M5XE 4C2ME 2R92E 5IYBE 2VUME 1SFOE 2E2JE 3GTGE 3HOXE 1TWFE 3M3YE 3GTLE 2NVXE 5M5WE 3GTQE 1Y1VE 4BBSE 5C3EE 4AYBH 4BY7E 4Y52E 1EIKA 3GTJE 1TWCE 3GTPE 3S1ME 5IYDE 5C4JE 3S16E 2B63E 4QIWH 3S15E 2Y0SH 4C3HE 3FKIE 3S17E 3HOWE 1TWAE 2NVQE 3GTOE 2YU9E 1I6HE 2WAQH 4A3EE 3RZDE 2JA5E 2NVTE 5IP7E 4A3JE 1DZFA 5M3FE 4Y7NE 3GTKE 2JA7E 4X6AE 2PMZH 3H3VF 1I50E 3S14E 4BXXE 1Y1WE
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5IP9 E;  3S1Q E;  4A3D E;  5FLM E;  2NVY E;  3PO3 E;  5IYC E;  4BBR E;  4A3F E;  2JA6 E;  2E2H E;  3S1N E;  2E2I E;  5FJ8 E;  1TWG E;  3M4O E;  3HOU E;  2R7Z E;  1I3Q E;  4C3J E;  3S1R E;  3I4N E;  4A3B E;  3RZO E;  3I4M E;  2R93 E;  4BY1 E;  4A3K E;  3H0G E;  3CQZ E;  3HOV E;  3K7A E;  3PO2 E;  4A3I E;  3HOY E;  4C3I E;  1R9T E;  5C44 E;  3HKZ H;  1WCM E;  3S2D E;  4A3L E;  4A3G E;  1TWH E;  5C4X E;  4A3M E;  2JA8 E;  3S2H E;  4A3C E;  2WB1 H;  3HOZ E;  1K83 E;  5M3M E;  5M5Y E;  4A93 E;  3GTM E;  5M5X E;  4C2M E;  2R92 E;  5IYB E;  2VUM E;  1SFO E;  2E2J E;  3GTG E;  3HOX E;  1TWF E;  3M3Y E;  3GTL E;  2NVX E;  5M5W E;  3GTQ E;  1Y1V E;  4BBS E;  5C3E E;  4AYB H;  4BY7 E;  4Y52 E;  1EIK A;  3GTJ E;  1TWC E;  3GTP E;  3S1M E;  5IYD E;  5C4J E;  3S16 E;  2B63 E;  4QIW H;  3S15 E;  2Y0S H;  4C3H E;  3FKI E;  3S17 E;  3HOW E;  1TWA E;  2NVQ E;  3GTO E;  2YU9 E;  1I6H E;  2WAQ H;  4A3E E;  3RZD E;  2JA5 E;  2NVT E;  5IP7 E;  4A3J E;  1DZF A;  5M3F E;  4Y7N E;  3GTK E;  2JA7 E;  4X6A E;  2PMZ H;  3H3V F;  1I50 E;  3S14 E;  4BXX E;  1Y1W E; 
#chains in the Genus database with same CATH topology
 4C3H F;  5IP9 E;  3S1Q E;  1YNN K;  4OIP E;  2A68 E;  4A3D E;  3FKI F;  5FLM E;  4OIQ E;  3S17 F;  2NVY E;  3HOW F;  3PO3 E;  5IYC E;  1TWA F;  3H3V G;  4BBR E;  4A3F E;  2JA6 E;  2E2H E;  4LK0 E;  3S1N E;  2E2I E;  2NVQ F;  5FJ8 E;  1TWG E;  4Q5S E;  3EQL E;  4YFX E;  3M4O E;  2WB1 I;  3GTO F;  3HOU E;  2R7Z E;  2YU9 F;  1I3Q E;  4AYB K;  1I6H F;  4C3J E;  3S1R E;  3I4N E;  4A3B E;  5BYH E;  4A3E F;  3RZD F;  2JA5 F;  2NVT F;  5IP7 F;  4A3J F;  3RZO E;  3I4M E;  2R93 E;  5M3F F;  4BY1 E;  4A3K E;  3H0G E;  4Y7N F;  3CQZ E;  3GTK F;  3HOV E;  3K7A E;  3PO2 E;  4A3I E;  3HOY E;  4Q4Z E;  4C3I E;  2JA7 F;  1R9T E;  4X6A F;  5C44 E;  3HKZ H;  1WCM E;  3S2D E;  4A3L E;  4A3G E;  1TWH E;  1I50 F;  1Y1W F;  3S14 F;  4BXX F;  4A3C F;  5C4X E;  5IP9 F;  4YFN E;  4A3M E;  2JA8 E;  3S2H E;  3S1Q F;  4A3D F;  5FLM F;  2NVY F;  3PO3 F;  5IYC F;  2CW0 E;  4A3C E;  2WB1 H;  4BBR F;  4QIW K;  3HOZ E;  4A3F F;  2JA6 F;  2E2H F;  3S1N F;  1K83 E;  2E2I F;  4YFK E;  5M3M E;  4MEY E;  1TWG F;  5FJ8 F;  5M5Y E;  4A93 E;  3GTM E;  4G7O E;  5M5X E;  4C2M E;  2R92 E;  2A69 E;  3HOU F;  5IYB E;  2R7Z F;  1I3Q F;  2VUM E;  3M4O F;  1SFO E;  2E2J E;  1I6V E;  4C3J F;  3GTG E;  3S1R F;  3HOX E;  3I4N F;  4A3B F;  1TWF E;  4YG2 E;  3M3Y F;  5D4D E;  3I4M F;  3RZO F;  2PPB E;  2R93 F;  4BY1 F;  4A3K F;  5TMC E;  4XLN E;  3H0G F;  3M3Y E;  3CQZ F;  2A6E E;  3HOV F;  3GTL E;  2NVX E;  3K7A F;  3PO2 F;  4A3I F;  3HOY F;  4C3I F;  1R9T F;  2WAQ K;  5M5W E;  5C44 F;  3GTQ E;  1Y1V E;  4BBS E;  1QKL A;  1TWH F;  1WCM F;  4LK1 E;  2O5I E;  3S2D F;  4A3L F;  4A3G F;  5C4X F;  4MEX E;  4A3M F;  2JA8 F;  5C3E E;  4AYB H;  3S2H F;  1SMY E;  4OIN E;  2Y0S I;  3WOD E;  3HOZ F;  4BY7 E;  3HKZ K;  1K83 F;  3DXJ E;  5M3M F;  2PMZ K;  4Y52 E;  5M5Y F;  4A93 F;  3GTM F;  5M5X F;  4C2M F;  2R92 F;  1EIK A;  4ZH4 E;  5IYB F;  5D4E E;  2VUM F;  1SFO F;  2E2J F;  3GTJ E;  5E17 E;  3GTG F;  3HOX F;  4KMU E;  1TWF F;  1IW7 E;  1TWC E;  4GZY E;  3GTP E;  1ZYR E;  3S1M E;  5IYD E;  5C4J E;  4OIO E;  3S16 E;  1HQM E;  2B63 E;  4QIW H;  2NVX F;  3S15 E;  3GTL F;  5IPL E;  5M5W F;  2Y0S H;  1Y1V F;  1YNJ K;  3GTQ F;  4BBS F;  4KN7 E;  4XSX E;  4C3H E;  5C3E F;  4XLP E;  4MQ9 E;  3FKI E;  3S17 E;  3HOW E;  1TWA E;  5E18 E;  4BY7 F;  4LLG E;  4OIR E;  2O5J E;  2NVQ E;  4Y52 F;  2A6H E;  3GTO E;  4G7H E;  2YU9 E;  1I6H E;  2WAQ H;  3GTJ F;  4A3E E;  3RZD E;  2JA5 E;  2KRX A;  2BE5 E;  1TWC F;  2NVT E;  5D4C E;  5IP7 E;  4A3J E;  3GTP F;  1DZF A;  3S1M F;  5M3F E;  4JK1 E;  4XSZ E;  5IYD F;  5C4J F;  4Y7N E;  3S16 F;  2B63 F;  3GTK E;  3S15 F;  5TMF E;  4KN4 E;  4LJZ E;  4G7Z E;  2JA7 E;  4X6A E;  2PMZ H;  3H3V F;  1I50 E;  3S14 E;  4BXX E;  1Y1W E; 
#chains in the Genus database with same CATH homology
 5IP9 E;  3S1Q E;  4A3D E;  5FLM E;  2NVY E;  3PO3 E;  5IYC E;  4BBR E;  4A3F E;  2JA6 E;  2E2H E;  3S1N E;  2E2I E;  5FJ8 E;  1TWG E;  3M4O E;  3HOU E;  2R7Z E;  1I3Q E;  4C3J E;  3S1R E;  3I4N E;  4A3B E;  3RZO E;  3I4M E;  2R93 E;  4BY1 E;  4A3K E;  3H0G E;  3CQZ E;  3HOV E;  3K7A E;  3PO2 E;  4A3I E;  3HOY E;  4C3I E;  1R9T E;  5C44 E;  3HKZ H;  1WCM E;  3S2D E;  4A3L E;  4A3G E;  1TWH E;  5C4X E;  4A3M E;  2JA8 E;  3S2H E;  4A3C E;  2WB1 H;  3HOZ E;  1K83 E;  5M3M E;  5M5Y E;  4A93 E;  3GTM E;  5M5X E;  4C2M E;  2R92 E;  5IYB E;  2VUM E;  1SFO E;  2E2J E;  3GTG E;  3HOX E;  1TWF E;  3M3Y E;  3GTL E;  2NVX E;  5M5W E;  3GTQ E;  1Y1V E;  4BBS E;  5C3E E;  4AYB H;  4BY7 E;  4Y52 E;  1EIK A;  3GTJ E;  1TWC E;  3GTP E;  3S1M E;  5IYD E;  5C4J E;  3S16 E;  2B63 E;  4QIW H;  3S15 E;  2Y0S H;  4C3H E;  3FKI E;  3S17 E;  3HOW E;  1TWA E;  2NVQ E;  3GTO E;  2YU9 E;  1I6H E;  2WAQ H;  4A3E E;  3RZD E;  2JA5 E;  2NVT E;  5IP7 E;  4A3J E;  1DZF A;  5M3F E;  4Y7N E;  3GTK E;  2JA7 E;  4X6A E;  2PMZ H;  3H3V F;  1I50 E;  3S14 E;  4BXX E;  1Y1W E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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