4A93E

Rna polymerase ii elongation complex containing a cpd lesion
Total Genus 62
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
62
sequence length
214
structure length
214
Chain Sequence
DQENERNISRLWRAFRTVKEMVKDRGYFITQEEVELPLEDFKAKYCDSMGRPQRKMMSFQANPTEESISKFPDMGSLWVEFCDEPSVGVKTMKTFVIHIQEKNFQTGIFVYQNNITPSAMKLVPSIPPATIETFNEAALVVNITHHELVPKHIRLSSDEKRELLKRYRLKESQLPRIQRADPVALYLGLKRGEVVKIIRKSETSGRYASYRICM
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mechanism of Translesion Transcription by RNA Polymerase II and its Role in Cellular Resistance to DNA Damage.
pubmed doi rcsb
molecule tags Transcription
molecule keywords DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1
total genus 62
structure length 214
sequence length 214
ec nomenclature
pdb deposition date 2011-11-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF01191 RNA_pol_Rpb5_C RNA polymerase Rpb5, C-terminal domain
E PF03871 RNA_pol_Rpb5_N RNA polymerase Rpb5, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1340.10 Alpha Beta 3-Layer(aba) Sandwich Dna-directed Rna Polymerases I, Ii, And Iii 27 Kd Polypeptide; Chain: A; domain 1 RNA polymerase, Rpb5, N-terminal domain 4a93E01
3.90.940.20 Alpha Beta Alpha-Beta Complex Eukaryotic RPB6 RNA polymerase subunit RPB5-like RNA polymerase subunit 4a93E02
5M5XE 3GTME 3GTOE 3H0GE 2WAQH 2NVQE 5IYBE 2JA5E 5C4JE 4BBSE 4A3KE 2NVXE 1WCME 4A3JE 3S2DE 3GTPE 3HKZH 1Y1VE 3CQZE 3RZDE 3S2HE 1Y1WE 4Y52E 2NVTE 3S1NE 3GTKE 2JA6E 3GTGE 3PO3E 3H3VF 3M4OE 4A3ME 4C3IE 5M3FE 5IYCE 5C3EE 3HOUE 1K83E 1SFOE 2JA8E 4A3DE 4BXXE 3GTQE 1R9TE 2PMZH 1I50E 5IP9E 4C3HE 5IP7E 4A3LE 2WB1H 2E2IE 4A3IE 3HOZE 4QIWH 5M3ME 5C4XE 4A3BE 1EIKA 3M3YE 3S1QE 5FJ8E 3HOYE 1TWHE 3PO2E 1I3QE 2R7ZE 3GTJE 4BBRE 2JA7E 4A3FE 4A3EE 4C2ME 5IYDE 2YU9E 1I6HE 2R92E 5M5WE 1DZFA 4AYBH 4BY7E 4X6AE 3HOVE 1TWAE 3RZOE 5C44E 2B63E 3S1ME 2E2JE 5FLME 1TWGE 3I4NE 3S16E 4A3GE 1TWFE 2R93E 2VUME 3GTLE 5M5YE 3FKIE 3S14E 4A93E 4C3JE 3HOWE 1TWCE 2E2HE 3S15E 3I4ME 4A3CE 3S17E 4Y7NE 3S1RE 3HOXE 2Y0SH 3K7AE 4BY1E 2NVYE
chains in the Genus database with same CATH superfamily
5M5XE 1WCMF 4A3JF 3GTME 2A6EE 4OIOE 3GTOE 3H0GE 4C2MF 3GTGF 2WAQH 2NVQE 5IYBF 5BYHE 4OIRE 4Y52F 5IYBE 1ZYRE 2JA5E 5C4JE 4BBSE 4A3KE 5E17E 3GTOF 5M5WF 1I3QF 2NVXE 4XSZE 4LK1E 1WCME 4A3JE 3S2DE 1I6VE 5M5XF 1I6HF 3GTPE 2Y0SI 3HKZH 3DXJE 1Y1VE 4YFXE 2PPBE 3CQZE 3RZDE 3S2HE 4BY1F 3S1QF 1Y1WE 1SMYE 4A3KF 4A3EF 4Y52E 2NVTE 5TMFE 3S1NE 4OIQE 2A68E 4A3BF 3GTKE 2JA7F 2JA6E 3GTGE 3PO3E 3H3VF 4BBRF 3M4OE 4A3ME 4C3IE 4YFNE 5D4CE 1TWHF 3HKZK 1YNNK 4Q4ZE 4C3HF 5M3FE 4MQ9E 5E18E 4Q5SE 3K7AF 5IYCE 2A6HE 5M5YF 2O5IE 1R9TF 3S17F 5C4XF 5C3EE 3HOUE 1QKLA 1K83E 1SFOE 2JA8E 4A3DE 4BXXE 3GTQE 2WAQK 1R9TE 4JK1E 5D4DE 4A3IF 2PMZH 4A3LF 4A3CF 3I4MF 5IP7F 1I50E 4C3JF 5IP9E 4C3HE 1TWGF 2A69E 4A93F 4MEYE 5IP7E 4OINE 3EQLE 4A3LE 2WB1H 2E2IE 4A3IE 4BXXF 4A3DF 3HOZE 4QIWH 4LLGE 4ZH4E 3HOUF 5M3ME 5C4XE 3GTKF 4GZYE 4A3BE 1TWAF 4LK0E 2NVTF 2R93F 1EIKA 1TWFF 3M3YE 1Y1WF 3S1QE 4OIPE 5M3FF 5FJ8E 5FLMF 1Y1VF 3HOYE 2R92F 3GTPF 5D4EE 3S2DF 1TWHE 3PO2E 1I3QE 4LJZE 2R7ZE 4A3MF 3M4OF 3GTJE 5TMCE 4BBRE 3WODE 4AYBK 4YFKE 2JA7E 2JA5F 3RZOF 4G7HE 3S1NF 4A3FE 2WB1I 4A3FF 4XSXE 4KMUE 3HOVF 2NVQF 4A3EE 4C2ME 3CQZF 3RZDF 2R7ZF 3GTMF 1YNJK 5IYDE 2YU9E 1I6HE 1IW7E 4KN4E 2R92E 5IYDF 2NVXF 2YU9F 5FJ8F 4XLPE 2NVYF 5M5WE 3HOYF 1DZFA 4AYBH 5C4JF 4BY7E 4X6AE 3HOXF 3HOVE 3S1RF 4BBSF 1TWAE 3RZOE 5C44E 5M3MF 3H0GF 3GTJF 4YG2E 3HOZF 2B63E 3S1ME 3PO2F 2E2JE 2CW0E 4G7OE 3HOWF 5FLME 1TWGE 5IP9F 3I4NE 3S16E 4KN7E 4QIWK 1I50F 4A3GE 3M3YF 1TWFE 3S14F 2R93E 3FKIF 2O5JE 4XLNE 4G7ZE 4Y7NF 3GTQF 3GTLF 1SFOF 2JA8F 2VUMF 2VUME 2BE5E 5C3EF 3GTLE 2KRXA 5M5YE 2PMZK 2E2IF 3FKIE 3S14E 3S15F 1TWCF 2E2HF 4A93E 3I4NF 3S16F 4C3JE 3HOWE 1TWCE 2E2HE 1HQME 3S15E 2E2JF 3I4ME 4A3CE 2B63F 3S1MF 4C3IF 1K83F 2JA6F 3PO3F 5C44F 3S17E 4Y7NE 3S1RE 3H3VG 5IYCF 3HOXE 2Y0SH 4BY7F 3K7AE 4A3GF 4X6AF 5IPLE 4BY1E 3S2HF 2NVYE 4MEXE
chains in the Genus database with same CATH topology
5M5XE 3GTME 3GTOE 3H0GE 2WAQH 2NVQE 5IYBE 2JA5E 5C4JE 4BBSE 4A3KE 2NVXE 1WCME 4A3JE 3S2DE 3GTPE 3HKZH 1Y1VE 3CQZE 3RZDE 3S2HE 1Y1WE 4Y52E 2NVTE 3S1NE 3GTKE 2JA6E 3GTGE 3PO3E 3H3VF 3M4OE 4A3ME 4C3IE 5M3FE 5IYCE 5C3EE 3HOUE 1K83E 1SFOE 2JA8E 4A3DE 4BXXE 3GTQE 1R9TE 2PMZH 1I50E 5IP9E 4C3HE 5IP7E 4A3LE 2WB1H 2E2IE 4A3IE 3HOZE 4QIWH 5M3ME 5C4XE 4A3BE 1EIKA 3M3YE 3S1QE 5FJ8E 3HOYE 1TWHE 3PO2E 1I3QE 2R7ZE 3GTJE 4BBRE 2JA7E 4A3FE 4A3EE 4C2ME 5IYDE 2YU9E 1I6HE 2R92E 5M5WE 1DZFA 4AYBH 4BY7E 4X6AE 3HOVE 1TWAE 3RZOE 5C44E 2B63E 3S1ME 2E2JE 5FLME 1TWGE 3I4NE 3S16E 4A3GE 1TWFE 2R93E 2VUME 3GTLE 5M5YE 3FKIE 3S14E 4A93E 4C3JE 3HOWE 1TWCE 2E2HE 3S15E 3I4ME 4A3CE 3S17E 4Y7NE 3S1RE 3HOXE 2Y0SH 3K7AE 4BY1E 2NVYE
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5M5X E;  3GTM E;  3GTO E;  3H0G E;  2WAQ H;  2NVQ E;  5IYB E;  2JA5 E;  5C4J E;  4BBS E;  4A3K E;  2NVX E;  1WCM E;  4A3J E;  3S2D E;  3GTP E;  3HKZ H;  1Y1V E;  3CQZ E;  3RZD E;  3S2H E;  1Y1W E;  4Y52 E;  2NVT E;  3S1N E;  3GTK E;  2JA6 E;  3GTG E;  3PO3 E;  3H3V F;  3M4O E;  4A3M E;  4C3I E;  5M3F E;  5IYC E;  5C3E E;  3HOU E;  1K83 E;  1SFO E;  2JA8 E;  4A3D E;  4BXX E;  3GTQ E;  1R9T E;  2PMZ H;  1I50 E;  5IP9 E;  4C3H E;  5IP7 E;  4A3L E;  2WB1 H;  2E2I E;  4A3I E;  3HOZ E;  4QIW H;  5M3M E;  5C4X E;  4A3B E;  1EIK A;  3M3Y E;  3S1Q E;  5FJ8 E;  3HOY E;  1TWH E;  3PO2 E;  1I3Q E;  2R7Z E;  3GTJ E;  4BBR E;  2JA7 E;  4A3F E;  4A3E E;  4C2M E;  5IYD E;  2YU9 E;  1I6H E;  2R92 E;  5M5W E;  1DZF A;  4AYB H;  4BY7 E;  4X6A E;  3HOV E;  1TWA E;  3RZO E;  5C44 E;  2B63 E;  3S1M E;  2E2J E;  5FLM E;  1TWG E;  3I4N E;  3S16 E;  4A3G E;  1TWF E;  2R93 E;  2VUM E;  3GTL E;  5M5Y E;  3FKI E;  3S14 E;  4A93 E;  4C3J E;  3HOW E;  1TWC E;  2E2H E;  3S15 E;  3I4M E;  4A3C E;  3S17 E;  4Y7N E;  3S1R E;  3HOX E;  2Y0S H;  3K7A E;  4BY1 E;  2NVY E; 
#chains in the Genus database with same CATH topology
 5M5X E;  1WCM F;  4A3J F;  3GTM E;  2A6E E;  4OIO E;  3GTO E;  3H0G E;  4C2M F;  3GTG F;  2WAQ H;  2NVQ E;  5IYB F;  5BYH E;  4OIR E;  4Y52 F;  5IYB E;  1ZYR E;  2JA5 E;  5C4J E;  4BBS E;  4A3K E;  5E17 E;  3GTO F;  5M5W F;  1I3Q F;  2NVX E;  4XSZ E;  4LK1 E;  1WCM E;  4A3J E;  3S2D E;  1I6V E;  5M5X F;  1I6H F;  3GTP E;  2Y0S I;  3HKZ H;  3DXJ E;  1Y1V E;  4YFX E;  2PPB E;  3CQZ E;  3RZD E;  3S2H E;  4BY1 F;  3S1Q F;  1Y1W E;  1SMY E;  4A3K F;  4A3E F;  4Y52 E;  2NVT E;  5TMF E;  3S1N E;  4OIQ E;  2A68 E;  4A3B F;  3GTK E;  2JA7 F;  2JA6 E;  3GTG E;  3PO3 E;  3H3V F;  4BBR F;  3M4O E;  4A3M E;  4C3I E;  4YFN E;  5D4C E;  1TWH F;  3HKZ K;  1YNN K;  4Q4Z E;  4C3H F;  5M3F E;  4MQ9 E;  5E18 E;  4Q5S E;  3K7A F;  5IYC E;  2A6H E;  5M5Y F;  2O5I E;  1R9T F;  3S17 F;  5C4X F;  5C3E E;  3HOU E;  1QKL A;  1K83 E;  1SFO E;  2JA8 E;  4A3D E;  4BXX E;  3GTQ E;  2WAQ K;  1R9T E;  4JK1 E;  5D4D E;  4A3I F;  2PMZ H;  4A3L F;  4A3C F;  3I4M F;  5IP7 F;  1I50 E;  4C3J F;  5IP9 E;  4C3H E;  1TWG F;  2A69 E;  4A93 F;  4MEY E;  5IP7 E;  4OIN E;  3EQL E;  4A3L E;  2WB1 H;  2E2I E;  4A3I E;  4BXX F;  4A3D F;  3HOZ E;  4QIW H;  4LLG E;  4ZH4 E;  3HOU F;  5M3M E;  5C4X E;  3GTK F;  4GZY E;  4A3B E;  1TWA F;  4LK0 E;  2NVT F;  2R93 F;  1EIK A;  1TWF F;  3M3Y E;  1Y1W F;  3S1Q E;  4OIP E;  5M3F F;  5FJ8 E;  5FLM F;  1Y1V F;  3HOY E;  2R92 F;  3GTP F;  5D4E E;  3S2D F;  1TWH E;  3PO2 E;  1I3Q E;  4LJZ E;  2R7Z E;  4A3M F;  3M4O F;  3GTJ E;  5TMC E;  4BBR E;  3WOD E;  4AYB K;  4YFK E;  2JA7 E;  2JA5 F;  3RZO F;  4G7H E;  3S1N F;  4A3F E;  2WB1 I;  4A3F F;  4XSX E;  4KMU E;  3HOV F;  2NVQ F;  4A3E E;  4C2M E;  3CQZ F;  3RZD F;  2R7Z F;  3GTM F;  1YNJ K;  5IYD E;  2YU9 E;  1I6H E;  1IW7 E;  4KN4 E;  2R92 E;  5IYD F;  2NVX F;  2YU9 F;  5FJ8 F;  4XLP E;  2NVY F;  5M5W E;  3HOY F;  1DZF A;  4AYB H;  5C4J F;  4BY7 E;  4X6A E;  3HOX F;  3HOV E;  3S1R F;  4BBS F;  1TWA E;  3RZO E;  5C44 E;  5M3M F;  3H0G F;  3GTJ F;  4YG2 E;  3HOZ F;  2B63 E;  3S1M E;  3PO2 F;  2E2J E;  2CW0 E;  4G7O E;  3HOW F;  5FLM E;  1TWG E;  5IP9 F;  3I4N E;  3S16 E;  4KN7 E;  4QIW K;  1I50 F;  4A3G E;  3M3Y F;  1TWF E;  3S14 F;  2R93 E;  3FKI F;  2O5J E;  4XLN E;  4G7Z E;  4Y7N F;  3GTQ F;  3GTL F;  1SFO F;  2JA8 F;  2VUM F;  2VUM E;  2BE5 E;  5C3E F;  3GTL E;  2KRX A;  5M5Y E;  2PMZ K;  2E2I F;  3FKI E;  3S14 E;  3S15 F;  1TWC F;  2E2H F;  4A93 E;  3I4N F;  3S16 F;  4C3J E;  3HOW E;  1TWC E;  2E2H E;  1HQM E;  3S15 E;  2E2J F;  3I4M E;  4A3C E;  2B63 F;  3S1M F;  4C3I F;  1K83 F;  2JA6 F;  3PO3 F;  5C44 F;  3S17 E;  4Y7N E;  3S1R E;  3H3V G;  5IYC F;  3HOX E;  2Y0S H;  4BY7 F;  3K7A E;  4A3G F;  4X6A F;  5IPL E;  4BY1 E;  3S2H F;  2NVY E;  4MEX E; 
#chains in the Genus database with same CATH homology
 5M5X E;  3GTM E;  3GTO E;  3H0G E;  2WAQ H;  2NVQ E;  5IYB E;  2JA5 E;  5C4J E;  4BBS E;  4A3K E;  2NVX E;  1WCM E;  4A3J E;  3S2D E;  3GTP E;  3HKZ H;  1Y1V E;  3CQZ E;  3RZD E;  3S2H E;  1Y1W E;  4Y52 E;  2NVT E;  3S1N E;  3GTK E;  2JA6 E;  3GTG E;  3PO3 E;  3H3V F;  3M4O E;  4A3M E;  4C3I E;  5M3F E;  5IYC E;  5C3E E;  3HOU E;  1K83 E;  1SFO E;  2JA8 E;  4A3D E;  4BXX E;  3GTQ E;  1R9T E;  2PMZ H;  1I50 E;  5IP9 E;  4C3H E;  5IP7 E;  4A3L E;  2WB1 H;  2E2I E;  4A3I E;  3HOZ E;  4QIW H;  5M3M E;  5C4X E;  4A3B E;  1EIK A;  3M3Y E;  3S1Q E;  5FJ8 E;  3HOY E;  1TWH E;  3PO2 E;  1I3Q E;  2R7Z E;  3GTJ E;  4BBR E;  2JA7 E;  4A3F E;  4A3E E;  4C2M E;  5IYD E;  2YU9 E;  1I6H E;  2R92 E;  5M5W E;  1DZF A;  4AYB H;  4BY7 E;  4X6A E;  3HOV E;  1TWA E;  3RZO E;  5C44 E;  2B63 E;  3S1M E;  2E2J E;  5FLM E;  1TWG E;  3I4N E;  3S16 E;  4A3G E;  1TWF E;  2R93 E;  2VUM E;  3GTL E;  5M5Y E;  3FKI E;  3S14 E;  4A93 E;  4C3J E;  3HOW E;  1TWC E;  2E2H E;  3S15 E;  3I4M E;  4A3C E;  3S17 E;  4Y7N E;  3S1R E;  3HOX E;  2Y0S H;  3K7A E;  4BY1 E;  2NVY E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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