4AIPA

The frpb iron transporter from neisseria meningitidis (f3-3 variant)
Total Genus 195
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
195
sequence length
682
structure length
661
Chain Sequence
DRQGSKIRTNIVTLQQKDESTATDMRELLKEEPSIDFGGGNGTSQFLTLRGMGQNSVDIKVDNAYSDSQILYHQGRFIVDPALVKVVSVQKGAGSASAGIGATNGAIIAKTVDAQDLLKGLDKNWGVRLNSGFASNNGVSYGASVFGKEGNFDGLFSYNRNDEKDYEAGKGFRNVNGGKTVPYSALDKRSYLAKIGTTFGDDDHRIVLSHMKDQHRGIRTVREEFTVGDKSSRINIDRQAPAYRETTQSNTNLAYTGKNLGFVEKLDANAYVLEKERYSADDSGTGYAGNVKGPNHTRITTRGANFNFDSRLAEQTLLKYGINYRHQEIKPQAFLNSKFSIPTPMEQQMKDRADEDTVHAYKLSNPTKTDTGVYIEAIHDIGDFTLTGGLRYDRFKVKTHDGKTVSSSNLNPSFGVIWQPHEHWSFSASHNYASRSPRLYDALQTHGKRGIISIADGTKAERARNTEIGFNYNDGTFAANGSYFWQTIKDALANPQAVREAVNAGYIKNHGYELGASYRTGGLTAKVGVSHSKPRFYDTHKDKLLSANPEFGAQVGRTWTASLAYRFQNPNLEIGWRGRYVQKATGSILAAGQKNLENVVRKGFGVNDVFANWKPLGKDTLNVNLSVNNVFNKFYYPHSQRWTNTLPGVGRDVRLGVNYKF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Use of a Molecular Decoy to Segregate Transport from Antigenicity in the Frpb Iron Transporter from Neisseria Meningitidis
pubmed doi rcsb
molecule tags Transport protein
source organism Neisseria meningitidis
molecule keywords FE-REGULATED PROTEIN B
total genus 195
structure length 661
sequence length 682
chains with identical sequence B, C
ec nomenclature
pdb deposition date 2012-02-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00593 TonB_dep_Rec TonB dependent receptor
A PF07715 Plug TonB-dependent Receptor Plug Domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.170.20 Mainly Beta Beta Barrel Maltoporin; Chain A TonB-dependent receptor, beta-barrel domain 4aipA02
2.170.130.10 Mainly Beta Beta Complex Ferric Hydroxamate Uptake Protein; Chain A, domain 1 TonB-dependent receptor, plug domain 4aipA01
4RDRA 1NQHA 2HDFA 1XKWA 2W6TA 3FHHA 1BY3A 1FEPA 3V8XA 1FCPA 1KMPA 1NQGA 3RGMA 1UJWA 4RDTA 3V89A 2W76A 1QFGA 3M8BA 4AIQA 4CU4A 3DDRA 4EPAA 1PO0A 2O5PA 2GRXA 1NQFA 3M8DA 1PNZA 4B7OA 1FI1A 1XKHA 2IAHA 3EFMA 2FCPA 4AIPA 2GUFA 2W16A 2W78A 3CSNA 2YSUA 5FOKA 3QLBA 3CSLA 1QKCA 2HDIA 2W77A 1BY5A 3RGNA 1KMOA 2W6UA 1NQEA 1QJQA 2GSKA 2W75A 1PO3A 1QFFA
chains in the Genus database with same CATH superfamily
4RDRA 1NQHA 2HDFA 1XKWA 2W6TA 3FHHA 1BY3A 1FEPA 1OH2P 1FCPA 1MPRA 3V8XA 3RGMA 1KMPA 1NQGA 1UJWA 4RDTA 3V89A 1MPNA 2W76A 1QFGA 3M8BA 4AIQA 4CU4A 1MALA 1MPQA 1MPOA 3DDRA 4EPAA 2O5PA 1PO0A 2GRXA 1NQFA 3M8DA 1PNZA 4B7OA 1FI1A 1XKHA 2IAHA 3EFMA 2FCPA 4AIPA 2GUFA 2W16A 2W78A 3CSNA 2YSUA 5FOKA 1A0TP 3QLBA 3CSLA 1QKCA 2HDIA 1MPMA 2W77A 1BY5A 3RGNA 1KMOA 1JBIA 2W6UA 1OH2Q 1NQEA 1QJQA 2GSKA 2MPRA 1A0SP 1AF6A 1PO3A 2W75A 1QFFA
chains in the Genus database with same CATH topology
4RDRA 1NQHA 2HDFA 1XKWA 2W6TA 3FHHA 1BY3A 1FEPA 3V8XA 1FCPA 1KMPA 1NQGA 3RGMA 1UJWA 4RDTA 3V89A 2W76A 1QFGA 3M8BA 4AIQA 4CU4A 3DDRA 4EPAA 1PO0A 2O5PA 2GRXA 1NQFA 3M8DA 1PNZA 4B7OA 1FI1A 1XKHA 2IAHA 3EFMA 2FCPA 4AIPA 2GUFA 2W16A 2W78A 3CSNA 2YSUA 5FOKA 3QLBA 3CSLA 1QKCA 2HDIA 2W77A 1BY5A 3RGNA 1KMOA 2W6UA 1NQEA 1QJQA 2GSKA 2W75A 1PO3A 1QFFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4RDR A;  1NQH A;  2HDF A;  1XKW A;  2W6T A;  3FHH A;  1BY3 A;  1FEP A;  3V8X A;  1FCP A;  1KMP A;  1NQG A;  3RGM A;  1UJW A;  4RDT A;  3V89 A;  2W76 A;  1QFG A;  3M8B A;  4AIQ A;  4CU4 A;  3DDR A;  4EPA A;  1PO0 A;  2O5P A;  2GRX A;  1NQF A;  3M8D A;  1PNZ A;  4B7O A;  1FI1 A;  1XKH A;  2IAH A;  3EFM A;  2FCP A;  4AIP A;  2GUF A;  2W16 A;  2W78 A;  3CSN A;  2YSU A;  5FOK A;  3QLB A;  3CSL A;  1QKC A;  2HDI A;  2W77 A;  1BY5 A;  3RGN A;  1KMO A;  2W6U A;  1NQE A;  1QJQ A;  2GSK A;  2W75 A;  1PO3 A;  1QFF A; 
#chains in the Genus database with same CATH topology
 4RDR A;  1NQH A;  2HDF A;  1XKW A;  2W6T A;  3FHH A;  1BY3 A;  1FEP A;  1OH2 P;  1FCP A;  1MPR A;  3V8X A;  3RGM A;  1KMP A;  1NQG A;  1UJW A;  4RDT A;  3V89 A;  1MPN A;  2W76 A;  1QFG A;  3M8B A;  4AIQ A;  4CU4 A;  1MAL A;  1MPQ A;  1MPO A;  3DDR A;  4EPA A;  2O5P A;  1PO0 A;  2GRX A;  1NQF A;  3M8D A;  1PNZ A;  4B7O A;  1FI1 A;  1XKH A;  2IAH A;  3EFM A;  2FCP A;  4AIP A;  2GUF A;  2W16 A;  2W78 A;  3CSN A;  2YSU A;  5FOK A;  1A0T P;  3QLB A;  3CSL A;  1QKC A;  2HDI A;  1MPM A;  2W77 A;  1BY5 A;  3RGN A;  1KMO A;  1JBI A;  2W6U A;  1OH2 Q;  1NQE A;  1QJQ A;  2GSK A;  2MPR A;  1A0S P;  1AF6 A;  1PO3 A;  2W75 A;  1QFF A; 
#chains in the Genus database with same CATH homology
 4RDR A;  1NQH A;  2HDF A;  1XKW A;  2W6T A;  3FHH A;  1BY3 A;  1FEP A;  3V8X A;  1FCP A;  1KMP A;  1NQG A;  3RGM A;  1UJW A;  4RDT A;  3V89 A;  2W76 A;  1QFG A;  3M8B A;  4AIQ A;  4CU4 A;  3DDR A;  4EPA A;  1PO0 A;  2O5P A;  2GRX A;  1NQF A;  3M8D A;  1PNZ A;  4B7O A;  1FI1 A;  1XKH A;  2IAH A;  3EFM A;  2FCP A;  4AIP A;  2GUF A;  2W16 A;  2W78 A;  3CSN A;  2YSU A;  5FOK A;  3QLB A;  3CSL A;  1QKC A;  2HDI A;  2W77 A;  1BY5 A;  3RGN A;  1KMO A;  2W6U A;  1NQE A;  1QJQ A;  2GSK A;  2W75 A;  1PO3 A;  1QFF A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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