4BNRI

Extremely stable complex of crayfish trypsin with bovine trypsin inhibitor
Total Genus 9
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
9
sequence length
58
structure length
58
Chain Sequence
RPDFCLEPPYTGPCKARIIRYFYNAKAGLCQTFVYGGCRAKRNNFKSAEDCMRTCGGA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Comparison of Complexes Formed by a Crustacean and a Vertebrate Trypsin with Bovine Pancreatic Trypsin Inhibitor - the Key to Achieving Extreme Stability?
pubmed doi rcsb
molecule tags Hydolase/inhibitor
molecule keywords HEPATOPANCREAS TRYPSIN
total genus 9
structure length 58
sequence length 58
chains with identical sequence J
ec nomenclature
pdb deposition date 2013-05-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
I PF00014 Kunitz_BPTI Kunitz/Bovine pancreatic trypsin inhibitor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.410.10 Few Secondary Structures Irregular Factor Xa Inhibitor Pancreatic trypsin inhibitor Kunitz domain 4bnrI00
2PTCI 1B0CA 3FP7J 2HEXA 3BTTI 2LFKA 1PITA 2FTLI 3FP8I 1TAWB 9PTIA 1JV9A 1AAPA 1KUNA 7PTIA 1YKTB 1F7ZI 3BTFI 4ISNB 3D65I 1AALA 2TGPI 1BIKA 2J6DA 1BZXI 1UUBA 4NTXB 2JOTA 2UUXA 2ZJXA 4NTYB 2ZVXA 1LD6A 1ADZA 3M7QB 1LD5A 2CA7A 2UUYB 8PTIA 1D0DB 1T8NB 1ZR0B 1ZJDB 4TPII 1TPAI 3BTQI 2DDJA 5JB6A 2RA3C 2KNTA 3LDMA 1P2OB 2FI3I 1OA65 3TGJI 3AUGA 3L33E 6PTIA 1YLDB 1BHCA 3BTDI 1BRBI 1T8LB 1T8OB 2W8XA 3BYBA 3UIRC 1P2MB 1BUNB 3P92E 4WWYC 3P95E 1P2II 3WNYA 1UUAA 4U30W 1P2QB 3LDJA 2IJOI 3T62D 1FANA 3BTGI 3BTEI 1SHPA 3AUCA 1YLCB 4BQDA 1JC6A 4WXVC 4Y10I 2LFLA 3BTWI 4BNRI 3BTHI 2FI4I 3AUIA 1K6UA 1BPTA 2TPII 1BF0A 2KCRA 1KNTA 4Y0YI 1G6XA 4PTIA 1BTIA 4ISLB 1KIGI 3OFWA 1P2NB 1Y62A 4DG4C 3AUDA 4U32X 2DDIA 3TGII 1CBWD 3OTJI 5JB7A 1T8MB 1JV8A 5JB5A 2R9PE 2M01A 3BTKI 1BZ5A 1BPIA 1DTXA 1P2KI 1MTND 1OA55 4Y0ZI 4NTWB 1D0DA 1CA0D 1DEMA 3U1JE 4BD9B 1BTHP 5JB4A 1F5RI 4ISOB 5PTIA 3L3TE 3FP6I 1TAPA 1TOCR 4DTGK 1QLQA 3CI7A 4Y11I 1IRHA 1EAWB 1DTKA 3BTMI 3AUBA 1BRCI 1TCPA 1TFXC 2KAII 3LDIA 5C67C 3TPII 2FI5I 1YC0I 1DENA 1P2JI 3TGKI 2FTMB 2ODYE 1CO7I 1EJMB 1FAKI 1FY8I 3AUHA 1T7CB 3UOUB 1NAGA 2M99A 1KTHA 3AUEA 3GYMI
chains in the Genus database with same CATH superfamily
2PTCI 1B0CA 3FP7J 2HEXA 3BTTI 2LFKA 1PITA 2FTLI 3FP8I 1TAWB 9PTIA 1JV9A 1AAPA 1KUNA 7PTIA 1YKTB 1F7ZI 3BTFI 4ISNB 3D65I 1AALA 2TGPI 1BIKA 2J6DA 1BZXI 1UUBA 4NTXB 2JOTA 2UUXA 2ZJXA 4NTYB 2ZVXA 1LD6A 1ADZA 3M7QB 1LD5A 2CA7A 2UUYB 8PTIA 1D0DB 1T8NB 1ZR0B 1ZJDB 4TPII 1TPAI 3BTQI 2DDJA 5JB6A 2RA3C 2KNTA 3LDMA 1P2OB 2FI3I 1OA65 3TGJI 3AUGA 3L33E 6PTIA 1YLDB 1BHCA 3BTDI 1BRBI 1T8LB 1T8OB 2W8XA 3BYBA 3UIRC 1P2MB 1BUNB 3P92E 4WWYC 3P95E 1P2II 3WNYA 1UUAA 4U30W 1P2QB 3LDJA 2IJOI 3T62D 1FANA 3BTGI 3BTEI 1SHPA 3AUCA 1YLCB 4BQDA 1JC6A 4WXVC 4Y10I 2LFLA 3BTWI 4BNRI 3BTHI 2FI4I 3AUIA 1K6UA 1BPTA 2TPII 1BF0A 2KCRA 1KNTA 4Y0YI 1G6XA 4PTIA 1BTIA 4ISLB 1KIGI 3OFWA 1P2NB 1Y62A 4DG4C 3AUDA 4U32X 2DDIA 3TGII 1CBWD 3OTJI 5JB7A 1T8MB 1JV8A 5JB5A 2R9PE 2M01A 3BTKI 1BZ5A 1BPIA 1DTXA 1P2KI 1MTND 1OA55 4Y0ZI 4NTWB 1D0DA 1CA0D 1DEMA 3U1JE 4BD9B 1BTHP 5JB4A 1F5RI 4ISOB 5PTIA 3L3TE 3FP6I 1TAPA 1TOCR 4DTGK 1QLQA 3CI7A 4Y11I 1IRHA 1EAWB 1DTKA 3BTMI 3AUBA 1BRCI 1TCPA 1TFXC 2KAII 3LDIA 5C67C 3TPII 2FI5I 1YC0I 1DENA 1P2JI 3TGKI 2FTMB 2ODYE 1CO7I 1EJMB 1FAKI 1FY8I 3AUHA 1T7CB 3UOUB 1NAGA 2M99A 1KTHA 3AUEA 3GYMI
chains in the Genus database with same CATH topology
2PTCI 1B0CA 3FP7J 2HEXA 3BTTI 2LFKA 1PITA 2FTLI 3FP8I 1TAWB 9PTIA 1JV9A 1AAPA 1KUNA 7PTIA 1YKTB 1F7ZI 3BTFI 4ISNB 3D65I 1AALA 2TGPI 1BIKA 2J6DA 1BZXI 1UUBA 4NTXB 2JOTA 2UUXA 2ZJXA 4NTYB 2ZVXA 1LD6A 1ADZA 3M7QB 1LD5A 2CA7A 2UUYB 8PTIA 1D0DB 1T8NB 1ZR0B 1ZJDB 4TPII 1TPAI 3BTQI 2DDJA 5JB6A 2RA3C 2KNTA 3LDMA 1P2OB 2FI3I 1OA65 3TGJI 3AUGA 3L33E 6PTIA 1YLDB 1BHCA 3BTDI 1BRBI 1T8LB 1T8OB 2W8XA 3BYBA 3UIRC 1P2MB 1BUNB 3P92E 4WWYC 3P95E 1P2II 3WNYA 1UUAA 4U30W 1P2QB 3LDJA 2IJOI 3T62D 1FANA 3BTGI 3BTEI 1SHPA 3AUCA 1YLCB 4BQDA 1JC6A 4WXVC 4Y10I 2LFLA 3BTWI 4BNRI 3BTHI 2FI4I 3AUIA 1K6UA 1BPTA 2TPII 1BF0A 2KCRA 1KNTA 4Y0YI 1G6XA 4PTIA 1BTIA 4ISLB 1KIGI 3OFWA 1P2NB 1Y62A 4DG4C 3AUDA 4U32X 2DDIA 3TGII 1CBWD 3OTJI 5JB7A 1T8MB 1JV8A 5JB5A 2R9PE 2M01A 3BTKI 1BZ5A 1BPIA 1DTXA 1P2KI 1MTND 1OA55 4Y0ZI 4NTWB 1D0DA 1CA0D 1DEMA 3U1JE 4BD9B 1BTHP 5JB4A 1F5RI 4ISOB 5PTIA 3L3TE 3FP6I 1TAPA 1TOCR 4DTGK 1QLQA 3CI7A 4Y11I 1IRHA 1EAWB 1DTKA 3BTMI 3AUBA 1BRCI 1TCPA 1TFXC 2KAII 3LDIA 5C67C 3TPII 2FI5I 1YC0I 1DENA 1P2JI 3TGKI 2FTMB 2ODYE 1CO7I 1EJMB 1FAKI 1FY8I 3AUHA 1T7CB 3UOUB 1NAGA 2M99A 1KTHA 3AUEA 3GYMI
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2PTC I;  1B0C A;  3FP7 J;  2HEX A;  3BTT I;  2LFK A;  1PIT A;  2FTL I;  3FP8 I;  1TAW B;  9PTI A;  1JV9 A;  1AAP A;  1KUN A;  7PTI A;  1YKT B;  1F7Z I;  3BTF I;  4ISN B;  3D65 I;  1AAL A;  2TGP I;  1BIK A;  2J6D A;  1BZX I;  1UUB A;  4NTX B;  2JOT A;  2UUX A;  2ZJX A;  4NTY B;  2ZVX A;  1LD6 A;  1ADZ A;  3M7Q B;  1LD5 A;  2CA7 A;  2UUY B;  8PTI A;  1D0D B;  1T8N B;  1ZR0 B;  1ZJD B;  4TPI I;  1TPA I;  3BTQ I;  2DDJ A;  5JB6 A;  2RA3 C;  2KNT A;  3LDM A;  1P2O B;  2FI3 I;  1OA6 5;  3TGJ I;  3AUG A;  3L33 E;  6PTI A;  1YLD B;  1BHC A;  3BTD I;  1BRB I;  1T8L B;  1T8O B;  2W8X A;  3BYB A;  3UIR C;  1P2M B;  1BUN B;  3P92 E;  4WWY C;  3P95 E;  1P2I I;  3WNY A;  1UUA A;  4U30 W;  1P2Q B;  3LDJ A;  2IJO I;  3T62 D;  1FAN A;  3BTG I;  3BTE I;  1SHP A;  3AUC A;  1YLC B;  4BQD A;  1JC6 A;  4WXV C;  4Y10 I;  2LFL A;  3BTW I;  4BNR I;  3BTH I;  2FI4 I;  3AUI A;  1K6U A;  1BPT A;  2TPI I;  1BF0 A;  2KCR A;  1KNT A;  4Y0Y I;  1G6X A;  4PTI A;  1BTI A;  4ISL B;  1KIG I;  3OFW A;  1P2N B;  1Y62 A;  4DG4 C;  3AUD A;  4U32 X;  2DDI A;  3TGI I;  1CBW D;  3OTJ I;  5JB7 A;  1T8M B;  1JV8 A;  5JB5 A;  2R9P E;  2M01 A;  3BTK I;  1BZ5 A;  1BPI A;  1DTX A;  1P2K I;  1MTN D;  1OA5 5;  4Y0Z I;  4NTW B;  1D0D A;  1CA0 D;  1DEM A;  3U1J E;  4BD9 B;  1BTH P;  5JB4 A;  1F5R I;  4ISO B;  5PTI A;  3L3T E;  3FP6 I;  1TAP A;  1TOC R;  4DTG K;  1QLQ A;  3CI7 A;  4Y11 I;  1IRH A;  1EAW B;  1DTK A;  3BTM I;  3AUB A;  1BRC I;  1TCP A;  1TFX C;  2KAI I;  3LDI A;  5C67 C;  3TPI I;  2FI5 I;  1YC0 I;  1DEN A;  1P2J I;  3TGK I;  2FTM B;  2ODY E;  1CO7 I;  1EJM B;  1FAK I;  1FY8 I;  3AUH A;  1T7C B;  3UOU B;  1NAG A;  2M99 A;  1KTH A;  3AUE A;  3GYM I; 
#chains in the Genus database with same CATH topology
 2PTC I;  1B0C A;  3FP7 J;  2HEX A;  3BTT I;  2LFK A;  1PIT A;  2FTL I;  3FP8 I;  1TAW B;  9PTI A;  1JV9 A;  1AAP A;  1KUN A;  7PTI A;  1YKT B;  1F7Z I;  3BTF I;  4ISN B;  3D65 I;  1AAL A;  2TGP I;  1BIK A;  2J6D A;  1BZX I;  1UUB A;  4NTX B;  2JOT A;  2UUX A;  2ZJX A;  4NTY B;  2ZVX A;  1LD6 A;  1ADZ A;  3M7Q B;  1LD5 A;  2CA7 A;  2UUY B;  8PTI A;  1D0D B;  1T8N B;  1ZR0 B;  1ZJD B;  4TPI I;  1TPA I;  3BTQ I;  2DDJ A;  5JB6 A;  2RA3 C;  2KNT A;  3LDM A;  1P2O B;  2FI3 I;  1OA6 5;  3TGJ I;  3AUG A;  3L33 E;  6PTI A;  1YLD B;  1BHC A;  3BTD I;  1BRB I;  1T8L B;  1T8O B;  2W8X A;  3BYB A;  3UIR C;  1P2M B;  1BUN B;  3P92 E;  4WWY C;  3P95 E;  1P2I I;  3WNY A;  1UUA A;  4U30 W;  1P2Q B;  3LDJ A;  2IJO I;  3T62 D;  1FAN A;  3BTG I;  3BTE I;  1SHP A;  3AUC A;  1YLC B;  4BQD A;  1JC6 A;  4WXV C;  4Y10 I;  2LFL A;  3BTW I;  4BNR I;  3BTH I;  2FI4 I;  3AUI A;  1K6U A;  1BPT A;  2TPI I;  1BF0 A;  2KCR A;  1KNT A;  4Y0Y I;  1G6X A;  4PTI A;  1BTI A;  4ISL B;  1KIG I;  3OFW A;  1P2N B;  1Y62 A;  4DG4 C;  3AUD A;  4U32 X;  2DDI A;  3TGI I;  1CBW D;  3OTJ I;  5JB7 A;  1T8M B;  1JV8 A;  5JB5 A;  2R9P E;  2M01 A;  3BTK I;  1BZ5 A;  1BPI A;  1DTX A;  1P2K I;  1MTN D;  1OA5 5;  4Y0Z I;  4NTW B;  1D0D A;  1CA0 D;  1DEM A;  3U1J E;  4BD9 B;  1BTH P;  5JB4 A;  1F5R I;  4ISO B;  5PTI A;  3L3T E;  3FP6 I;  1TAP A;  1TOC R;  4DTG K;  1QLQ A;  3CI7 A;  4Y11 I;  1IRH A;  1EAW B;  1DTK A;  3BTM I;  3AUB A;  1BRC I;  1TCP A;  1TFX C;  2KAI I;  3LDI A;  5C67 C;  3TPI I;  2FI5 I;  1YC0 I;  1DEN A;  1P2J I;  3TGK I;  2FTM B;  2ODY E;  1CO7 I;  1EJM B;  1FAK I;  1FY8 I;  3AUH A;  1T7C B;  3UOU B;  1NAG A;  2M99 A;  1KTH A;  3AUE A;  3GYM I; 
#chains in the Genus database with same CATH homology
 2PTC I;  1B0C A;  3FP7 J;  2HEX A;  3BTT I;  2LFK A;  1PIT A;  2FTL I;  3FP8 I;  1TAW B;  9PTI A;  1JV9 A;  1AAP A;  1KUN A;  7PTI A;  1YKT B;  1F7Z I;  3BTF I;  4ISN B;  3D65 I;  1AAL A;  2TGP I;  1BIK A;  2J6D A;  1BZX I;  1UUB A;  4NTX B;  2JOT A;  2UUX A;  2ZJX A;  4NTY B;  2ZVX A;  1LD6 A;  1ADZ A;  3M7Q B;  1LD5 A;  2CA7 A;  2UUY B;  8PTI A;  1D0D B;  1T8N B;  1ZR0 B;  1ZJD B;  4TPI I;  1TPA I;  3BTQ I;  2DDJ A;  5JB6 A;  2RA3 C;  2KNT A;  3LDM A;  1P2O B;  2FI3 I;  1OA6 5;  3TGJ I;  3AUG A;  3L33 E;  6PTI A;  1YLD B;  1BHC A;  3BTD I;  1BRB I;  1T8L B;  1T8O B;  2W8X A;  3BYB A;  3UIR C;  1P2M B;  1BUN B;  3P92 E;  4WWY C;  3P95 E;  1P2I I;  3WNY A;  1UUA A;  4U30 W;  1P2Q B;  3LDJ A;  2IJO I;  3T62 D;  1FAN A;  3BTG I;  3BTE I;  1SHP A;  3AUC A;  1YLC B;  4BQD A;  1JC6 A;  4WXV C;  4Y10 I;  2LFL A;  3BTW I;  4BNR I;  3BTH I;  2FI4 I;  3AUI A;  1K6U A;  1BPT A;  2TPI I;  1BF0 A;  2KCR A;  1KNT A;  4Y0Y I;  1G6X A;  4PTI A;  1BTI A;  4ISL B;  1KIG I;  3OFW A;  1P2N B;  1Y62 A;  4DG4 C;  3AUD A;  4U32 X;  2DDI A;  3TGI I;  1CBW D;  3OTJ I;  5JB7 A;  1T8M B;  1JV8 A;  5JB5 A;  2R9P E;  2M01 A;  3BTK I;  1BZ5 A;  1BPI A;  1DTX A;  1P2K I;  1MTN D;  1OA5 5;  4Y0Z I;  4NTW B;  1D0D A;  1CA0 D;  1DEM A;  3U1J E;  4BD9 B;  1BTH P;  5JB4 A;  1F5R I;  4ISO B;  5PTI A;  3L3T E;  3FP6 I;  1TAP A;  1TOC R;  4DTG K;  1QLQ A;  3CI7 A;  4Y11 I;  1IRH A;  1EAW B;  1DTK A;  3BTM I;  3AUB A;  1BRC I;  1TCP A;  1TFX C;  2KAI I;  3LDI A;  5C67 C;  3TPI I;  2FI5 I;  1YC0 I;  1DEN A;  1P2J I;  3TGK I;  2FTM B;  2ODY E;  1CO7 I;  1EJM B;  1FAK I;  1FY8 I;  3AUH A;  1T7C B;  3UOU B;  1NAG A;  2M99 A;  1KTH A;  3AUE A;  3GYM I; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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