4C3HE

Structure of 14-subunit rna polymerase i at 3.27 a resolution, crystal form c2-93
Total Genus 65
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
65
sequence length
215
structure length
215
Chain Sequence
MDQENERNISRLWRAFRTVKEMVKDRGYFITQEEVELPLEDFKAKYCDSMGRPQRKMMSFQANPTEESISKFPDMGSLWVEFCDEPSVGVKTMKTFVIHIQEKNFQTGIFVYQNNITPSAMKLVPSIPPATIETFNEAALVVNITHHELVPKHIRLSSDEKRELLKRYRLKESQLPRIQRADPVALYLGLKRGEVVKIIRKSETSGRYASYRICM
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of the 14-Subunit RNA Polymerase I
pubmed doi rcsb
molecule tags Transcription
molecule keywords DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA190
total genus 65
structure length 215
sequence length 215
ec nomenclature
pdb deposition date 2013-08-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF01191 RNA_pol_Rpb5_C RNA polymerase Rpb5, C-terminal domain
E PF03871 RNA_pol_Rpb5_N RNA polymerase Rpb5, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1340.10 Alpha Beta 3-Layer(aba) Sandwich Dna-directed Rna Polymerases I, Ii, And Iii 27 Kd Polypeptide; Chain: A; domain 1 RNA polymerase, Rpb5, N-terminal domain 4c3hE01
3.90.940.20 Alpha Beta Alpha-Beta Complex Eukaryotic RPB6 RNA polymerase subunit RPB5-like RNA polymerase subunit 4c3hE02
3HOXE 3CQZE 4X6AE 2R93E 3GTJE 4A3DE 4Y52E 3HOWE 3K7AE 5IYBE 2R7ZE 3S1ME 1TWHE 2PMZH 3HKZH 3GTQE 4C3IE 2WAQH 2NVQE 2JA7E 3FKIE 5FJ8E 2NVTE 3GTME 4A93E 3S15E 3S16E 2Y0SH 3H3VF 2E2HE 3PO2E 4A3CE 2JA8E 3I4NE 1SFOE 3GTLE 4A3IE 4A3GE 3HOYE 5C4XE 3GTPE 3S2HE 4AYBH 3HOZE 1I6HE 3GTKE 2YU9E 1EIKA 1TWGE 2VUME 1I50E 5IP9E 3PO3E 2R92E 5C44E 4A3EE 1Y1VE 2E2IE 5M3FE 1DZFA 4C3HE 4BXXE 4A3LE 3S1NE 4A3FE 2JA5E 3S17E 2E2JE 3S1QE 1TWAE 5IYCE 1TWCE 4Y7NE 3HOUE 3I4ME 3RZOE 4BY7E 4A3ME 4C3JE 1WCME 2NVYE 5M5WE 5M5XE 4A3KE 5FLME 4C2ME 3HOVE 3S14E 5M5YE 5M3ME 4A3JE 3H0GE 4QIWH 5C3EE 2JA6E 3S2DE 3GTGE 1Y1WE 3M4OE 1TWFE 4BBSE 2B63E 5IP7E 1K83E 3M3YE 3RZDE 1I3QE 3S1RE 4A3BE 4BBRE 2NVXE 1R9TE 5IYDE 5C4JE 4BY1E 3GTOE 2WB1H
chains in the Genus database with same CATH superfamily
1TWGF 2YU9F 2BE5E 2JA7F 3FKIF 3HOXE 3CQZE 2NVTF 4X6AE 2R92F 2R93E 3GTJE 4A3DE 4Y52E 4G7OE 1Y1VF 5BYHE 3S16F 5M3FF 4KMUE 4C3HF 4BXXF 3HOWE 3WODE 4A3LF 5TMCE 4MEYE 3K7AE 1SMYE 5IYBE 2R7ZE 3S1ME 2E2HF 4A3FF 2JA5F 1TWHE 4XLNE 3S17F 2PMZH 2E2JF 3HKZH 3GTQE 4C3IE 2WAQH 5IYCF 2NVQE 2JA7E 1TWCF 3FKIE 4Y7NF 5FJ8E 4GZYE 2NVTE 2A69E 1SFOF 3GTLF 4ZH4E 3GTME 4XSZE 4A3MF 4C3JF 4A93E 3S15E 1WCMF 4YG2E 4A3IF 3HOYF 3S16E 3S1QF 5C4XF 2Y0SH 4A3KF 3GTPF 5FLMF 3GTKF 3H3VF 1I6HF 3HOVF 2PPBE 2A6EE 3S14F 2VUMF 5E17E 2A68E 4KN4E 1IW7E 5M5YF 2E2HE 1I50F 5IP9F 3PO3F 3PO2E 5M3MF 5C44F 4OIRE 4A3JF 4OINE 4Q4ZE 4A3CE 1YNNK 4XLPE 2JA8E 3H0GF 4A3EF 4AYBK 2PMZK 2E2IF 3I4NE 3HKZK 1SFOE 3GTLE 2JA6F 2WAQK 4OIQE 4A3IE 4A3GE 3HOYE 3S1NF 5C4XE 3GTPE 3S2HE 4AYBH 3M4OF 3HOZE 1TWFF 1I6HE 3GTKE 2YU9E 1TWAF 1ZYRE 1TWGE 4OIPE 4A3BF 4BBSF 2VUME 2A6HE 1EIKA 3HOUF 1I50E 5IP9E 3PO3E 2R92E 5C44E 4LK0E 4BY7F 3I4MF 3RZOF 5IP7F 5IPLE 2NVYF 4A3EE 1Y1VE 1I3QF 2CW0E 5M5WF 3RZDF 5M5XF 2E2IE 5M3FE 4MEXE 1DZFA 4C3HE 4BXXE 4BBRF 4C2MF 5D4EE 1YNJK 4A3LE 2NVXF 4G7ZE 5D4DE 5C4JF 4BY1F 3S1NE 4A3FE 2JA5E 3S17E 2E2JE 3S1QE 4Q5SE 1TWAE 5IYCE 1TWCE 4Y7NE 3HOUE 4MQ9E 5C3EF 4X6AF 3I4ME 4G7HE 3RZOE 4BY7E 3S2DF 4A3ME 4C3JE 3GTJF 4A3DF 3GTGF 1WCME 2NVYE 5M5WE 4LJZE 5M5XE 4A3KE 1Y1WF 5FLME 4C2ME 3HOVE 4JK1E 5D4CE 3S14E 2R7ZF 3S1MF 3DXJE 5M5YE 3EQLE 2B63F 4YFKE 1TWHF 5M3ME 2WB1I 4C3IF 4A3JE 2NVQF 1K83F 3M3YF 5FJ8F 3H0GE 4QIWH 5C3EE 3S1RF 3GTMF 2JA6E 1R9TF 3S2DE 4A93F 3S15F 3GTGE 1QKLA 5IYDF 4LLGE 3GTOF 1Y1WE 3M4OE 1TWFE 4BBSE 5E18E 1I6VE 3HOXF 3CQZF 2B63E 3H3VG 4YFXE 4XSXE 3PO2F 4LK1E 4KN7E 2R93F 2O5JE 5IP7E 4Y52F 4A3CF 1K83E 3M3YE 5TMFE 3RZDE 1I3QE 2JA8F 3I4NF 2O5IE 4OIOE 3S1RE 4A3BE 4YFNE 4BBRE 3HOWF 2NVXE 2KRXA 1R9TE 3K7AF 4A3GF 4QIWK 5IYBF 5IYDE 5C4JE 4BY1E 3GTOE 3S2HF 2WB1H 2Y0SI 3HOZF 1HQME 3GTQF
chains in the Genus database with same CATH topology
3HOXE 3CQZE 4X6AE 2R93E 3GTJE 4A3DE 4Y52E 3HOWE 3K7AE 5IYBE 2R7ZE 3S1ME 1TWHE 2PMZH 3HKZH 3GTQE 4C3IE 2WAQH 2NVQE 2JA7E 3FKIE 5FJ8E 2NVTE 3GTME 4A93E 3S15E 3S16E 2Y0SH 3H3VF 2E2HE 3PO2E 4A3CE 2JA8E 3I4NE 1SFOE 3GTLE 4A3IE 4A3GE 3HOYE 5C4XE 3GTPE 3S2HE 4AYBH 3HOZE 1I6HE 3GTKE 2YU9E 1EIKA 1TWGE 2VUME 1I50E 5IP9E 3PO3E 2R92E 5C44E 4A3EE 1Y1VE 2E2IE 5M3FE 1DZFA 4C3HE 4BXXE 4A3LE 3S1NE 4A3FE 2JA5E 3S17E 2E2JE 3S1QE 1TWAE 5IYCE 1TWCE 4Y7NE 3HOUE 3I4ME 3RZOE 4BY7E 4A3ME 4C3JE 1WCME 2NVYE 5M5WE 5M5XE 4A3KE 5FLME 4C2ME 3HOVE 3S14E 5M5YE 5M3ME 4A3JE 3H0GE 4QIWH 5C3EE 2JA6E 3S2DE 3GTGE 1Y1WE 3M4OE 1TWFE 4BBSE 2B63E 5IP7E 1K83E 3M3YE 3RZDE 1I3QE 3S1RE 4A3BE 4BBRE 2NVXE 1R9TE 5IYDE 5C4JE 4BY1E 3GTOE 2WB1H
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3HOX E;  3CQZ E;  4X6A E;  2R93 E;  3GTJ E;  4A3D E;  4Y52 E;  3HOW E;  3K7A E;  5IYB E;  2R7Z E;  3S1M E;  1TWH E;  2PMZ H;  3HKZ H;  3GTQ E;  4C3I E;  2WAQ H;  2NVQ E;  2JA7 E;  3FKI E;  5FJ8 E;  2NVT E;  3GTM E;  4A93 E;  3S15 E;  3S16 E;  2Y0S H;  3H3V F;  2E2H E;  3PO2 E;  4A3C E;  2JA8 E;  3I4N E;  1SFO E;  3GTL E;  4A3I E;  4A3G E;  3HOY E;  5C4X E;  3GTP E;  3S2H E;  4AYB H;  3HOZ E;  1I6H E;  3GTK E;  2YU9 E;  1EIK A;  1TWG E;  2VUM E;  1I50 E;  5IP9 E;  3PO3 E;  2R92 E;  5C44 E;  4A3E E;  1Y1V E;  2E2I E;  5M3F E;  1DZF A;  4C3H E;  4BXX E;  4A3L E;  3S1N E;  4A3F E;  2JA5 E;  3S17 E;  2E2J E;  3S1Q E;  1TWA E;  5IYC E;  1TWC E;  4Y7N E;  3HOU E;  3I4M E;  3RZO E;  4BY7 E;  4A3M E;  4C3J E;  1WCM E;  2NVY E;  5M5W E;  5M5X E;  4A3K E;  5FLM E;  4C2M E;  3HOV E;  3S14 E;  5M5Y E;  5M3M E;  4A3J E;  3H0G E;  4QIW H;  5C3E E;  2JA6 E;  3S2D E;  3GTG E;  1Y1W E;  3M4O E;  1TWF E;  4BBS E;  2B63 E;  5IP7 E;  1K83 E;  3M3Y E;  3RZD E;  1I3Q E;  3S1R E;  4A3B E;  4BBR E;  2NVX E;  1R9T E;  5IYD E;  5C4J E;  4BY1 E;  3GTO E;  2WB1 H; 
#chains in the Genus database with same CATH topology
 1TWG F;  2YU9 F;  2BE5 E;  2JA7 F;  3FKI F;  3HOX E;  3CQZ E;  2NVT F;  4X6A E;  2R92 F;  2R93 E;  3GTJ E;  4A3D E;  4Y52 E;  4G7O E;  1Y1V F;  5BYH E;  3S16 F;  5M3F F;  4KMU E;  4C3H F;  4BXX F;  3HOW E;  3WOD E;  4A3L F;  5TMC E;  4MEY E;  3K7A E;  1SMY E;  5IYB E;  2R7Z E;  3S1M E;  2E2H F;  4A3F F;  2JA5 F;  1TWH E;  4XLN E;  3S17 F;  2PMZ H;  2E2J F;  3HKZ H;  3GTQ E;  4C3I E;  2WAQ H;  5IYC F;  2NVQ E;  2JA7 E;  1TWC F;  3FKI E;  4Y7N F;  5FJ8 E;  4GZY E;  2NVT E;  2A69 E;  1SFO F;  3GTL F;  4ZH4 E;  3GTM E;  4XSZ E;  4A3M F;  4C3J F;  4A93 E;  3S15 E;  1WCM F;  4YG2 E;  4A3I F;  3HOY F;  3S16 E;  3S1Q F;  5C4X F;  2Y0S H;  4A3K F;  3GTP F;  5FLM F;  3GTK F;  3H3V F;  1I6H F;  3HOV F;  2PPB E;  2A6E E;  3S14 F;  2VUM F;  5E17 E;  2A68 E;  4KN4 E;  1IW7 E;  5M5Y F;  2E2H E;  1I50 F;  5IP9 F;  3PO3 F;  3PO2 E;  5M3M F;  5C44 F;  4OIR E;  4A3J F;  4OIN E;  4Q4Z E;  4A3C E;  1YNN K;  4XLP E;  2JA8 E;  3H0G F;  4A3E F;  4AYB K;  2PMZ K;  2E2I F;  3I4N E;  3HKZ K;  1SFO E;  3GTL E;  2JA6 F;  2WAQ K;  4OIQ E;  4A3I E;  4A3G E;  3HOY E;  3S1N F;  5C4X E;  3GTP E;  3S2H E;  4AYB H;  3M4O F;  3HOZ E;  1TWF F;  1I6H E;  3GTK E;  2YU9 E;  1TWA F;  1ZYR E;  1TWG E;  4OIP E;  4A3B F;  4BBS F;  2VUM E;  2A6H E;  1EIK A;  3HOU F;  1I50 E;  5IP9 E;  3PO3 E;  2R92 E;  5C44 E;  4LK0 E;  4BY7 F;  3I4M F;  3RZO F;  5IP7 F;  5IPL E;  2NVY F;  4A3E E;  1Y1V E;  1I3Q F;  2CW0 E;  5M5W F;  3RZD F;  5M5X F;  2E2I E;  5M3F E;  4MEX E;  1DZF A;  4C3H E;  4BXX E;  4BBR F;  4C2M F;  5D4E E;  1YNJ K;  4A3L E;  2NVX F;  4G7Z E;  5D4D E;  5C4J F;  4BY1 F;  3S1N E;  4A3F E;  2JA5 E;  3S17 E;  2E2J E;  3S1Q E;  4Q5S E;  1TWA E;  5IYC E;  1TWC E;  4Y7N E;  3HOU E;  4MQ9 E;  5C3E F;  4X6A F;  3I4M E;  4G7H E;  3RZO E;  4BY7 E;  3S2D F;  4A3M E;  4C3J E;  3GTJ F;  4A3D F;  3GTG F;  1WCM E;  2NVY E;  5M5W E;  4LJZ E;  5M5X E;  4A3K E;  1Y1W F;  5FLM E;  4C2M E;  3HOV E;  4JK1 E;  5D4C E;  3S14 E;  2R7Z F;  3S1M F;  3DXJ E;  5M5Y E;  3EQL E;  2B63 F;  4YFK E;  1TWH F;  5M3M E;  2WB1 I;  4C3I F;  4A3J E;  2NVQ F;  1K83 F;  3M3Y F;  5FJ8 F;  3H0G E;  4QIW H;  5C3E E;  3S1R F;  3GTM F;  2JA6 E;  1R9T F;  3S2D E;  4A93 F;  3S15 F;  3GTG E;  1QKL A;  5IYD F;  4LLG E;  3GTO F;  1Y1W E;  3M4O E;  1TWF E;  4BBS E;  5E18 E;  1I6V E;  3HOX F;  3CQZ F;  2B63 E;  3H3V G;  4YFX E;  4XSX E;  3PO2 F;  4LK1 E;  4KN7 E;  2R93 F;  2O5J E;  5IP7 E;  4Y52 F;  4A3C F;  1K83 E;  3M3Y E;  5TMF E;  3RZD E;  1I3Q E;  2JA8 F;  3I4N F;  2O5I E;  4OIO E;  3S1R E;  4A3B E;  4YFN E;  4BBR E;  3HOW F;  2NVX E;  2KRX A;  1R9T E;  3K7A F;  4A3G F;  4QIW K;  5IYB F;  5IYD E;  5C4J E;  4BY1 E;  3GTO E;  3S2H F;  2WB1 H;  2Y0S I;  3HOZ F;  1HQM E;  3GTQ F; 
#chains in the Genus database with same CATH homology
 3HOX E;  3CQZ E;  4X6A E;  2R93 E;  3GTJ E;  4A3D E;  4Y52 E;  3HOW E;  3K7A E;  5IYB E;  2R7Z E;  3S1M E;  1TWH E;  2PMZ H;  3HKZ H;  3GTQ E;  4C3I E;  2WAQ H;  2NVQ E;  2JA7 E;  3FKI E;  5FJ8 E;  2NVT E;  3GTM E;  4A93 E;  3S15 E;  3S16 E;  2Y0S H;  3H3V F;  2E2H E;  3PO2 E;  4A3C E;  2JA8 E;  3I4N E;  1SFO E;  3GTL E;  4A3I E;  4A3G E;  3HOY E;  5C4X E;  3GTP E;  3S2H E;  4AYB H;  3HOZ E;  1I6H E;  3GTK E;  2YU9 E;  1EIK A;  1TWG E;  2VUM E;  1I50 E;  5IP9 E;  3PO3 E;  2R92 E;  5C44 E;  4A3E E;  1Y1V E;  2E2I E;  5M3F E;  1DZF A;  4C3H E;  4BXX E;  4A3L E;  3S1N E;  4A3F E;  2JA5 E;  3S17 E;  2E2J E;  3S1Q E;  1TWA E;  5IYC E;  1TWC E;  4Y7N E;  3HOU E;  3I4M E;  3RZO E;  4BY7 E;  4A3M E;  4C3J E;  1WCM E;  2NVY E;  5M5W E;  5M5X E;  4A3K E;  5FLM E;  4C2M E;  3HOV E;  3S14 E;  5M5Y E;  5M3M E;  4A3J E;  3H0G E;  4QIW H;  5C3E E;  2JA6 E;  3S2D E;  3GTG E;  1Y1W E;  3M4O E;  1TWF E;  4BBS E;  2B63 E;  5IP7 E;  1K83 E;  3M3Y E;  3RZD E;  1I3Q E;  3S1R E;  4A3B E;  4BBR E;  2NVX E;  1R9T E;  5IYD E;  5C4J E;  4BY1 E;  3GTO E;  2WB1 H; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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