4C3HF

Structure of 14-subunit rna polymerase i at 3.27 a resolution, crystal form c2-93
Total Genus 32
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
32
sequence length
100
structure length
100
Chain Sequence
PEDFQQHEQIRRKTLKEKAIPKDQRATTPYMTKYERARILGTRALQISMNAPVFVDLEGETDPLRIAMKELAEKKIPLVIRRYLPDGSFEDWSVEELIVD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of the 14-Subunit RNA Polymerase I
pubmed doi rcsb
molecule tags Transcription
molecule keywords DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA190
total genus 32
structure length 100
sequence length 100
ec nomenclature
pdb deposition date 2013-08-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
F PF01192 RNA_pol_Rpb6 RNA polymerase Rpb6
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.940.10 Alpha Beta Alpha-Beta Complex Eukaryotic RPB6 RNA polymerase subunit Eukaryotic RPB6 RNA polymerase subunit 4c3hF00
4A3GF 2JA8F 4XLNE 4JK1E 5C3EF 4MEYE 3FKIF 4BBRF 1TWAF 2NVQF 3I4NF 3K7AF 3HOYF 1SMYE 5C4JF 1R9TF 1K83F 3HOVF 5M3FF 4A3LF 4GZYE 2NVTF 4BY7F 5D4EE 3M3YF 5IP9F 4YG2E 4C2MF 2E2IF 5C4XF 2NVYF 4BY1F 3GTPF 4OIOE 3EQLE 5IYDF 5FLMF 1TWHF 3HOUF 3M4OF 2A68E 3S1NF 4LK0E 1ZYRE 4C3JF 2JA5F 5M5YF 4OIQE 4A3FF 4KN7E 3PO2F 4Y52F 2R92F 4A3KF 5IP7F 4A3CF 3S2HF 2R7ZF 1Y1VF 4Q4ZE 3GTGF 3S17F 4A3JF 1I50F 1YNJK 5M3MF 5C44F 4XSZE 5E18E 2B63F 3GTJF 5E17E 1TWGF 1TWFF 5M5WF 4BBSF 4LJZE 1HQME 1Y1WF 4C3HF 3WODE 3RZDF 2NVXF 5BYHE 5M5XF 3GTKF 3HOZF 4YFKE 3DXJE 2A69E 1TWCF 2WB1I 4YFNE 3PO3F 4A3BF 4A3IF 3S1RF 3S15F 2E2JF 2A6HE 4A3MF 1I6HF 2O5IE 3S2DF 3HOWF 2O5JE 2A6EE 4MEXE 3GTLF 4X6AF 3I4MF 2CW0E 4A3DF 1IW7E 4OIPE 3S1MF 4C3IF 2JA6F 1I6VE 5IYBF 1WCMF 5FJ8F 4LLGE 4Y7NF 4XSXE 4G7HE 4BXXF 3HKZK 5IPLE 4AYBK 4KN4E 2JA7F 3H0GF 4Q5SE 2E2HF 2YU9F 2Y0SI 1QKLA 2BE5E 5D4DE 2WAQK 4OIRE 4G7OE 4ZH4E 4OINE 3S1QF 2PPBE 4XLPE 3CQZF 4LK1E 2R93F 4MQ9E 3GTMF 4KMUE 3H3VG 5D4CE 1YNNK 5IYCF 3S14F 4A93F 1SFOF 3HOXF 2VUMF 3GTOF 4A3EF 4G7ZE 2PMZK 4YFXE 5TMFE 3S16F 1I3QF 5TMCE 3RZOF 3GTQF
chains in the Genus database with same CATH superfamily
4A3GF 2JA8F 3S16E 1I3QE 2PMZH 3RZOE 5IYDE 3GTQE 2R93E 4XLNE 4JK1E 5C3EF 2JA8E 4A3GE 4MEYE 3FKIF 4BBRF 1TWAF 2NVQF 3I4NF 3K7AF 3FKIE 1TWAE 3I4NE 3HOYF 3K7AE 1SMYE 3HOYE 5C4JF 1R9TF 1K83F 3HOVF 5M3FF 4A3LF 5C4JE 4GZYE 1R9TE 1K83E 2NVTF 4BY7F 5D4EE 5M3FE 5IP9F 4YG2E 3HOVE 4C2MF 2E2IF 3M3YF 4A3LE 2WB1H 2NVTE 4BY7E 2NVYF 3M3YE 5IP9E 5C4XF 4BY1F 4C2ME 3GTPF 4OIOE 5C4XE 2NVYE 4BY1E 3GTPE 3EQLE 5IYDF 1EIKA 5FLMF 1TWHF 3H3VF 5FLME 3HOUF 1TWHE 3M4OF 2A68E 3S1NF 4LK0E 1ZYRE 3HOUE 4C3JF 2JA5F 5M5YF 4OIQE 4A3FF 4KN7E 3M4OE 3PO2F 4A3BE 3S1NE 4Y52F 2R92F 4C3JE 2JA5E 5M5YE 4A3KF 4A3FE 5IP7F 3PO2E 4A3CF 3S2HF 2R7ZF 1Y1VF 4Q4ZE 2R92E 3GTGF 4Y52E 4A3KE 5IP7E 4A3CE 3S17F 3S2HE 2R7ZE 1Y1VE 4A3JF 1I50F 3GTGE 1YNJK 5M3MF 3S17E 5C44F 4A3JE 4XSZE 1I50E 5E18E 2B63F 5M3ME 5C44E 2Y0SH 3GTJF 5E17E 2B63E 1TWGF 1TWFF 4C3IE 5M5WF 2JA6E 3GTJE 4Y7NE 4BBSF 1TWGE 1TWFE 4LJZE 1HQME 5M5WE 1Y1WF 4C3HF 3WODE 3RZDF 2NVXF 5BYHE 5M5XF 3GTKF 3HOZF 4BBSE 4YFKE 3DXJE 1Y1WE 4C3HE 3HKZH 3GTKE 3RZDE 2A69E 1TWCF 2WB1I 5M5XE 2NVXE 3HOZE 4YFNE 1TWCE 3PO3F 4A3BF 4A3IF 3S1RF 3S15F 2E2JF 2A6HE 4A3MF 1I6HF 2O5IE 4A3IE 3S1RE 3HOWF 3S15E 3PO3E 3S2DF 2O5JE 2A6EE 4MEXE 4A3ME 2KRXA 2E2JE 3GTLF 1I6HE 3S2DE 3HOWE 4X6AF 3I4MF 2CW0E 3GTLE 4X6AE 4A3DF 3I4ME 1IW7E 4OIPE 4A93E 4A3DE 3S1MF 4C3IF 2JA6F 1I6VE 5IYBF 1WCMF 5FJ8F 4LLGE 4Y7NF 3S1ME 4XSXE 5IYBE 1WCME 5FJ8E 4G7HE 4BXXF 3HKZK 2E2HE 5IPLE 4AYBK 4KN4E 4BXXE 2JA7F 1DZFA 3H0GF 4Q5SE 2E2HF 2YU9F 2JA7E 2Y0SI 4AYBH 5C3EE 3H0GE 1QKLA 2BE5E 5D4DE 2WAQK 4OIRE 4BBRE 2YU9E 2NVQE 4G7OE 4ZH4E 4OINE 3S1QF 2PPBE 2WAQH 4XLPE 3CQZF 4LK1E 2R93F 3S1QE 4MQ9E 3GTMF 4KMUE 3H3VG 5D4CE 1YNNK 3CQZE 5IYCF 4QIWK 3S14F 3GTME 4A93F 1SFOF 5IYCE 3HOXF 2VUMF 3GTOF 2E2IE 4A3EF 3S14E 4G7ZE 1SFOE 4QIWH 2PMZK 4YFXE 3HOXE 2VUME 4A3EE 3GTOE 5TMFE 3S16F 1I3QF 5TMCE 3RZOF 3GTQF
chains in the Genus database with same CATH topology
4A3GF 2JA8F 4XLNE 4JK1E 5C3EF 4MEYE 3FKIF 4BBRF 1TWAF 2NVQF 3I4NF 3K7AF 3HOYF 1SMYE 5C4JF 1R9TF 1K83F 3HOVF 5M3FF 4A3LF 4GZYE 2NVTF 4BY7F 5D4EE 3M3YF 5IP9F 4YG2E 4C2MF 2E2IF 5C4XF 2NVYF 4BY1F 3GTPF 4OIOE 3EQLE 5IYDF 5FLMF 1TWHF 3HOUF 3M4OF 2A68E 3S1NF 4LK0E 1ZYRE 4C3JF 2JA5F 5M5YF 4OIQE 4A3FF 4KN7E 3PO2F 4Y52F 2R92F 4A3KF 5IP7F 4A3CF 3S2HF 2R7ZF 1Y1VF 4Q4ZE 3GTGF 3S17F 4A3JF 1I50F 1YNJK 5M3MF 5C44F 4XSZE 5E18E 2B63F 3GTJF 5E17E 1TWGF 1TWFF 5M5WF 4BBSF 4LJZE 1HQME 1Y1WF 4C3HF 3WODE 3RZDF 2NVXF 5BYHE 5M5XF 3GTKF 3HOZF 4YFKE 3DXJE 2A69E 1TWCF 2WB1I 4YFNE 3PO3F 4A3BF 4A3IF 3S1RF 3S15F 2E2JF 2A6HE 4A3MF 1I6HF 2O5IE 3S2DF 3HOWF 2O5JE 2A6EE 4MEXE 3GTLF 2KRXA 4X6AF 3I4MF 2CW0E 4A3DF 1IW7E 4OIPE 3S1MF 4C3IF 2JA6F 1I6VE 5IYBF 1WCMF 5FJ8F 4LLGE 4Y7NF 4XSXE 4G7HE 4BXXF 3HKZK 5IPLE 4AYBK 4KN4E 2JA7F 3H0GF 4Q5SE 2E2HF 2YU9F 2Y0SI 1QKLA 2BE5E 5D4DE 2WAQK 4OIRE 4G7OE 4ZH4E 4OINE 3S1QF 2PPBE 4XLPE 3CQZF 4LK1E 2R93F 4MQ9E 3GTMF 4KMUE 3H3VG 5D4CE 1YNNK 5IYCF 4QIWK 3S14F 4A93F 1SFOF 3HOXF 2VUMF 3GTOF 4A3EF 4G7ZE 2PMZK 4YFXE 5TMFE 3S16F 1I3QF 5TMCE 3RZOF 3GTQF
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4A3G F;  2JA8 F;  4XLN E;  4JK1 E;  5C3E F;  4MEY E;  3FKI F;  4BBR F;  1TWA F;  2NVQ F;  3I4N F;  3K7A F;  3HOY F;  1SMY E;  5C4J F;  1R9T F;  1K83 F;  3HOV F;  5M3F F;  4A3L F;  4GZY E;  2NVT F;  4BY7 F;  5D4E E;  3M3Y F;  5IP9 F;  4YG2 E;  4C2M F;  2E2I F;  5C4X F;  2NVY F;  4BY1 F;  3GTP F;  4OIO E;  3EQL E;  5IYD F;  5FLM F;  1TWH F;  3HOU F;  3M4O F;  2A68 E;  3S1N F;  4LK0 E;  1ZYR E;  4C3J F;  2JA5 F;  5M5Y F;  4OIQ E;  4A3F F;  4KN7 E;  3PO2 F;  4Y52 F;  2R92 F;  4A3K F;  5IP7 F;  4A3C F;  3S2H F;  2R7Z F;  1Y1V F;  4Q4Z E;  3GTG F;  3S17 F;  4A3J F;  1I50 F;  1YNJ K;  5M3M F;  5C44 F;  4XSZ E;  5E18 E;  2B63 F;  3GTJ F;  5E17 E;  1TWG F;  1TWF F;  5M5W F;  4BBS F;  4LJZ E;  1HQM E;  1Y1W F;  4C3H F;  3WOD E;  3RZD F;  2NVX F;  5BYH E;  5M5X F;  3GTK F;  3HOZ F;  4YFK E;  3DXJ E;  2A69 E;  1TWC F;  2WB1 I;  4YFN E;  3PO3 F;  4A3B F;  4A3I F;  3S1R F;  3S15 F;  2E2J F;  2A6H E;  4A3M F;  1I6H F;  2O5I E;  3S2D F;  3HOW F;  2O5J E;  2A6E E;  4MEX E;  3GTL F;  4X6A F;  3I4M F;  2CW0 E;  4A3D F;  1IW7 E;  4OIP E;  3S1M F;  4C3I F;  2JA6 F;  1I6V E;  5IYB F;  1WCM F;  5FJ8 F;  4LLG E;  4Y7N F;  4XSX E;  4G7H E;  4BXX F;  3HKZ K;  5IPL E;  4AYB K;  4KN4 E;  2JA7 F;  3H0G F;  4Q5S E;  2E2H F;  2YU9 F;  2Y0S I;  1QKL A;  2BE5 E;  5D4D E;  2WAQ K;  4OIR E;  4G7O E;  4ZH4 E;  4OIN E;  3S1Q F;  2PPB E;  4XLP E;  3CQZ F;  4LK1 E;  2R93 F;  4MQ9 E;  3GTM F;  4KMU E;  3H3V G;  5D4C E;  1YNN K;  5IYC F;  3S14 F;  4A93 F;  1SFO F;  3HOX F;  2VUM F;  3GTO F;  4A3E F;  4G7Z E;  2PMZ K;  4YFX E;  5TMF E;  3S16 F;  1I3Q F;  5TMC E;  3RZO F;  3GTQ F; 
#chains in the Genus database with same CATH topology
 4A3G F;  2JA8 F;  3S16 E;  1I3Q E;  2PMZ H;  3RZO E;  5IYD E;  3GTQ E;  2R93 E;  4XLN E;  4JK1 E;  5C3E F;  2JA8 E;  4A3G E;  4MEY E;  3FKI F;  4BBR F;  1TWA F;  2NVQ F;  3I4N F;  3K7A F;  3FKI E;  1TWA E;  3I4N E;  3HOY F;  3K7A E;  1SMY E;  3HOY E;  5C4J F;  1R9T F;  1K83 F;  3HOV F;  5M3F F;  4A3L F;  5C4J E;  4GZY E;  1R9T E;  1K83 E;  2NVT F;  4BY7 F;  5D4E E;  5M3F E;  5IP9 F;  4YG2 E;  3HOV E;  4C2M F;  2E2I F;  3M3Y F;  4A3L E;  2WB1 H;  2NVT E;  4BY7 E;  2NVY F;  3M3Y E;  5IP9 E;  5C4X F;  4BY1 F;  4C2M E;  3GTP F;  4OIO E;  5C4X E;  2NVY E;  4BY1 E;  3GTP E;  3EQL E;  5IYD F;  1EIK A;  5FLM F;  1TWH F;  3H3V F;  5FLM E;  3HOU F;  1TWH E;  3M4O F;  2A68 E;  3S1N F;  4LK0 E;  1ZYR E;  3HOU E;  4C3J F;  2JA5 F;  5M5Y F;  4OIQ E;  4A3F F;  4KN7 E;  3M4O E;  3PO2 F;  4A3B E;  3S1N E;  4Y52 F;  2R92 F;  4C3J E;  2JA5 E;  5M5Y E;  4A3K F;  4A3F E;  5IP7 F;  3PO2 E;  4A3C F;  3S2H F;  2R7Z F;  1Y1V F;  4Q4Z E;  2R92 E;  3GTG F;  4Y52 E;  4A3K E;  5IP7 E;  4A3C E;  3S17 F;  3S2H E;  2R7Z E;  1Y1V E;  4A3J F;  1I50 F;  3GTG E;  1YNJ K;  5M3M F;  3S17 E;  5C44 F;  4A3J E;  4XSZ E;  1I50 E;  5E18 E;  2B63 F;  5M3M E;  5C44 E;  2Y0S H;  3GTJ F;  5E17 E;  2B63 E;  1TWG F;  1TWF F;  4C3I E;  5M5W F;  2JA6 E;  3GTJ E;  4Y7N E;  4BBS F;  1TWG E;  1TWF E;  4LJZ E;  1HQM E;  5M5W E;  1Y1W F;  4C3H F;  3WOD E;  3RZD F;  2NVX F;  5BYH E;  5M5X F;  3GTK F;  3HOZ F;  4BBS E;  4YFK E;  3DXJ E;  1Y1W E;  4C3H E;  3HKZ H;  3GTK E;  3RZD E;  2A69 E;  1TWC F;  2WB1 I;  5M5X E;  2NVX E;  3HOZ E;  4YFN E;  1TWC E;  3PO3 F;  4A3B F;  4A3I F;  3S1R F;  3S15 F;  2E2J F;  2A6H E;  4A3M F;  1I6H F;  2O5I E;  4A3I E;  3S1R E;  3HOW F;  3S15 E;  3PO3 E;  3S2D F;  2O5J E;  2A6E E;  4MEX E;  4A3M E;  2KRX A;  2E2J E;  3GTL F;  1I6H E;  3S2D E;  3HOW E;  4X6A F;  3I4M F;  2CW0 E;  3GTL E;  4X6A E;  4A3D F;  3I4M E;  1IW7 E;  4OIP E;  4A93 E;  4A3D E;  3S1M F;  4C3I F;  2JA6 F;  1I6V E;  5IYB F;  1WCM F;  5FJ8 F;  4LLG E;  4Y7N F;  3S1M E;  4XSX E;  5IYB E;  1WCM E;  5FJ8 E;  4G7H E;  4BXX F;  3HKZ K;  2E2H E;  5IPL E;  4AYB K;  4KN4 E;  4BXX E;  2JA7 F;  1DZF A;  3H0G F;  4Q5S E;  2E2H F;  2YU9 F;  2JA7 E;  2Y0S I;  4AYB H;  5C3E E;  3H0G E;  1QKL A;  2BE5 E;  5D4D E;  2WAQ K;  4OIR E;  4BBR E;  2YU9 E;  2NVQ E;  4G7O E;  4ZH4 E;  4OIN E;  3S1Q F;  2PPB E;  2WAQ H;  4XLP E;  3CQZ F;  4LK1 E;  2R93 F;  3S1Q E;  4MQ9 E;  3GTM F;  4KMU E;  3H3V G;  5D4C E;  1YNN K;  3CQZ E;  5IYC F;  4QIW K;  3S14 F;  3GTM E;  4A93 F;  1SFO F;  5IYC E;  3HOX F;  2VUM F;  3GTO F;  2E2I E;  4A3E F;  3S14 E;  4G7Z E;  1SFO E;  4QIW H;  2PMZ K;  4YFX E;  3HOX E;  2VUM E;  4A3E E;  3GTO E;  5TMF E;  3S16 F;  1I3Q F;  5TMC E;  3RZO F;  3GTQ F; 
#chains in the Genus database with same CATH homology
 4A3G F;  2JA8 F;  4XLN E;  4JK1 E;  5C3E F;  4MEY E;  3FKI F;  4BBR F;  1TWA F;  2NVQ F;  3I4N F;  3K7A F;  3HOY F;  1SMY E;  5C4J F;  1R9T F;  1K83 F;  3HOV F;  5M3F F;  4A3L F;  4GZY E;  2NVT F;  4BY7 F;  5D4E E;  3M3Y F;  5IP9 F;  4YG2 E;  4C2M F;  2E2I F;  5C4X F;  2NVY F;  4BY1 F;  3GTP F;  4OIO E;  3EQL E;  5IYD F;  5FLM F;  1TWH F;  3HOU F;  3M4O F;  2A68 E;  3S1N F;  4LK0 E;  1ZYR E;  4C3J F;  2JA5 F;  5M5Y F;  4OIQ E;  4A3F F;  4KN7 E;  3PO2 F;  4Y52 F;  2R92 F;  4A3K F;  5IP7 F;  4A3C F;  3S2H F;  2R7Z F;  1Y1V F;  4Q4Z E;  3GTG F;  3S17 F;  4A3J F;  1I50 F;  1YNJ K;  5M3M F;  5C44 F;  4XSZ E;  5E18 E;  2B63 F;  3GTJ F;  5E17 E;  1TWG F;  1TWF F;  5M5W F;  4BBS F;  4LJZ E;  1HQM E;  1Y1W F;  4C3H F;  3WOD E;  3RZD F;  2NVX F;  5BYH E;  5M5X F;  3GTK F;  3HOZ F;  4YFK E;  3DXJ E;  2A69 E;  1TWC F;  2WB1 I;  4YFN E;  3PO3 F;  4A3B F;  4A3I F;  3S1R F;  3S15 F;  2E2J F;  2A6H E;  4A3M F;  1I6H F;  2O5I E;  3S2D F;  3HOW F;  2O5J E;  2A6E E;  4MEX E;  3GTL F;  2KRX A;  4X6A F;  3I4M F;  2CW0 E;  4A3D F;  1IW7 E;  4OIP E;  3S1M F;  4C3I F;  2JA6 F;  1I6V E;  5IYB F;  1WCM F;  5FJ8 F;  4LLG E;  4Y7N F;  4XSX E;  4G7H E;  4BXX F;  3HKZ K;  5IPL E;  4AYB K;  4KN4 E;  2JA7 F;  3H0G F;  4Q5S E;  2E2H F;  2YU9 F;  2Y0S I;  1QKL A;  2BE5 E;  5D4D E;  2WAQ K;  4OIR E;  4G7O E;  4ZH4 E;  4OIN E;  3S1Q F;  2PPB E;  4XLP E;  3CQZ F;  4LK1 E;  2R93 F;  4MQ9 E;  3GTM F;  4KMU E;  3H3V G;  5D4C E;  1YNN K;  5IYC F;  4QIW K;  3S14 F;  4A93 F;  1SFO F;  3HOX F;  2VUM F;  3GTO F;  4A3E F;  4G7Z E;  2PMZ K;  4YFX E;  5TMF E;  3S16 F;  1I3Q F;  5TMC E;  3RZO F;  3GTQ F; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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