4C3IE

Structure of 14-subunit rna polymerase i at 3.0 a resolution, crystal form c2-100
Total Genus 64
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
64
sequence length
215
structure length
215
Chain Sequence
MDQENERNISRLWRAFRTVKEMVKDRGYFITQEEVELPLEDFKAKYCDSMGRPQRKMMSFQANPTEESISKFPDMGSLWVEFCDEPSVGVKTMKTFVIHIQEKNFQTGIFVYQNNITPSAMKLVPSIPPATIETFNEAALVVNITHHELVPKHIRLSSDEKRELLKRYRLKESQLPRIQRADPVALYLGLKRGEVVKIIRKSETSGRYASYRICM
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Crystal Structure of the 14-Subunit RNA Polymerase I
pubmed doi rcsb
molecule tags Transferase
molecule keywords DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA190
total genus 64
structure length 215
sequence length 215
ec nomenclature
pdb deposition date 2013-08-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF01191 RNA_pol_Rpb5_C RNA polymerase Rpb5, C-terminal domain
E PF03871 RNA_pol_Rpb5_N RNA polymerase Rpb5, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1340.10 Alpha Beta 3-Layer(aba) Sandwich Dna-directed Rna Polymerases I, Ii, And Iii 27 Kd Polypeptide; Chain: A; domain 1 RNA polymerase, Rpb5, N-terminal domain 4c3iE01
3.90.940.20 Alpha Beta Alpha-Beta Complex Eukaryotic RPB6 RNA polymerase subunit RPB5-like RNA polymerase subunit 4c3iE02
3HKZH 1WCME 3GTGE 2Y0SH 1TWGE 3S17E 5C4XE 4A3DE 3S1QE 4AYBH 4C3HE 4C3IE 5IP7E 2JA8E 4BY1E 3CQZE 3S2HE 2E2HE 2WAQH 3HOVE 3I4NE 1R9TE 5C44E 5FJ8E 2JA6E 1TWCE 3PO2E 4BBSE 4X6AE 5FLME 2E2IE 2NVXE 3GTLE 4A93E 1SFOE 3K7AE 4A3FE 1K83E 3GTOE 3S1ME 2NVTE 5M3ME 4Y7NE 3RZOE 4QIWH 5M3FE 4A3EE 5M5WE 5C4JE 3HOWE 3HOXE 3GTME 1I50E 3GTQE 2NVQE 2JA7E 3H3VF 1Y1VE 2VUME 5M5XE 2YU9E 2B63E 1EIKA 4C3JE 3GTJE 3GTKE 4A3BE 5IYBE 1TWAE 4A3JE 2JA5E 5M5YE 3S1RE 2WB1H 3PO3E 2R93E 2E2JE 1TWHE 3I4ME 3S1NE 4Y52E 2R92E 3M3YE 4BXXE 4A3CE 4BBRE 4A3GE 4A3ME 3FKIE 5C3EE 1TWFE 1Y1WE 3HOUE 3S14E 1I6HE 4A3IE 1I3QE 5IYCE 3HOZE 5IYDE 4A3LE 3S16E 2NVYE 3H0GE 2PMZH 3GTPE 1DZFA 2R7ZE 4A3KE 3S2DE 5IP9E 3RZDE 3HOYE 4BY7E 4C2ME 3S15E 3M4OE
chains in the Genus database with same CATH superfamily
3HKZH 4A3GF 3PO3F 1WCME 4A3MF 3GTGE 3FKIF 5C3EF 2Y0SH 1TWFF 1Y1WF 4ZH4E 3HOUF 3S14F 1TWGE 3S17E 5C4XE 4A3DE 3S17F 3EQLE 1I6HF 4A3IF 3S1QE 1I3QF 4AYBH 4C3HE 5IYCF 3HOZF 4C3IE 5IP7E 2JA8E 5IYDF 3DXJE 2JA8F 4A3LF 3S16F 4BY1E 1ZYRE 1YNJK 1SMYE 2NVYF 3H0GF 4LK0E 4XSZE 3CQZE 3S2HE 2E2HE 2WAQH 3GTPF 3HOVE 3I4NE 1R9TE 5C44E 2BE5E 2PMZK 4A3KF 5IP9F 1R9TF 2R7ZF 3S2DF 5FJ8E 2JA6E 1TWCE 2WAQK 3PO2E 4BBSE 3RZDF 2Y0SI 4BY7F 3HOYF 4C2MF 4X6AE 3M4OF 3S15F 4Q5SE 5FLME 2E2IE 2NVXE 3GTLE 4A93E 1WCMF 3HKZK 5D4CE 3GTGF 1SFOE 3K7AE 4A3FE 1K83E 3GTOE 1IW7E 3S1ME 5D4DE 3H3VG 2NVTE 5M3ME 4Y7NE 3RZOE 1TWGF 4A3DF 5M3MF 5C4XF 3RZOF 4JK1E 4MEYE 4G7OE 4QIWH 3S1QF 5M3FE 4C3HF 4A3EE 5M5WE 5C4JE 4MQ9E 3HOWE 4AYBK 4C3IF 4QIWK 5IP7F 4LLGE 3HOXE 3GTME 4BY1F 1I50E 3GTQE 2A68E 2NVQE 3CQZF 3S2HF 2E2HF 2JA7E 2PPBE 3HOVF 3I4NF 5C44F 2R93F 4KN4E 4XSXE 3H3VF 4Q4ZE 5FJ8F 2JA6F 1TWCF 3PO2F 1Y1VE 4BBSF 5E17E 2VUME 4X6AF 5M5XE 5TMCE 5FLMF 2YU9E 2E2IF 2B63E 3WODE 4G7ZE 4XLNE 2NVXF 2WB1I 3GTLF 4A93F 4C3JE 1EIKA 2A6HE 5IPLE 3GTJE 3GTKE 3K7AF 4A3FF 1K83F 1SFOF 3GTOF 4A3BE 5IYBE 3S1MF 1I6VE 2NVTF 1TWAE 4A3JE 2JA5E 4Y7NF 5M5YE 3S1RE 2WB1H 3PO3E 4OIOE 2R93E 2E2JE 3S1RF 5M3FF 1TWHE 4A3EF 5M5WF 3I4ME 5C4JF 4YFXE 3S1NE 3HOWF 4Y52E 1QKLA 3HOXF 2R92E 3M3YE 4BXXE 2A69E 4YFNE 3GTMF 4BXXF 1I50F 4A3CE 3GTQF 4GZYE 2NVQF 4BBRE 4A3GE 2JA7F 4A3ME 3FKIE 5C3EE 1HQME 1TWFE 1Y1VF 4G7HE 1Y1WE 4LJZE 3HOUE 2A6EE 3S14E 2VUMF 5M5XF 4YG2E 2YU9F 1I6HE 4A3IE 5TMFE 1I3QE 2B63F 5IYCE 4C3JF 3HOZE 5D4EE 5IYDE 3GTJF 3GTKF 4A3LE 4YFKE 4A3BF 3S16E 4OIQE 5IYBF 4MEXE 2NVYE 3H0GE 1TWAF 4A3JF 2JA5F 2PMZH 5M5YF 2KRXA 4LK1E 3GTPE 4KMUE 1YNNK 1DZFA 5BYHE 5E18E 2E2JF 2R7ZE 2CW0E 4A3KE 3S2DE 5IP9E 1TWHF 2O5IE 3I4MF 4XLPE 3S1NF 2O5JE 3RZDE 3HOYE 4BY7E 4Y52F 4C2ME 2R92F 3M3YF 4OIPE 3S15E 3M4OE 4OIRE 4A3CF 4OINE 4KN7E 4BBRF
chains in the Genus database with same CATH topology
3HKZH 1WCME 3GTGE 2Y0SH 1TWGE 3S17E 5C4XE 4A3DE 3S1QE 4AYBH 4C3HE 4C3IE 5IP7E 2JA8E 4BY1E 3CQZE 3S2HE 2E2HE 2WAQH 3HOVE 3I4NE 1R9TE 5C44E 5FJ8E 2JA6E 1TWCE 3PO2E 4BBSE 4X6AE 5FLME 2E2IE 2NVXE 3GTLE 4A93E 1SFOE 3K7AE 4A3FE 1K83E 3GTOE 3S1ME 2NVTE 5M3ME 4Y7NE 3RZOE 4QIWH 5M3FE 4A3EE 5M5WE 5C4JE 3HOWE 3HOXE 3GTME 1I50E 3GTQE 2NVQE 2JA7E 3H3VF 1Y1VE 2VUME 5M5XE 2YU9E 2B63E 1EIKA 4C3JE 3GTJE 3GTKE 4A3BE 5IYBE 1TWAE 4A3JE 2JA5E 5M5YE 3S1RE 2WB1H 3PO3E 2R93E 2E2JE 1TWHE 3I4ME 3S1NE 4Y52E 2R92E 3M3YE 4BXXE 4A3CE 4BBRE 4A3GE 4A3ME 3FKIE 5C3EE 1TWFE 1Y1WE 3HOUE 3S14E 1I6HE 4A3IE 1I3QE 5IYCE 3HOZE 5IYDE 4A3LE 3S16E 2NVYE 3H0GE 2PMZH 3GTPE 1DZFA 2R7ZE 4A3KE 3S2DE 5IP9E 3RZDE 3HOYE 4BY7E 4C2ME 3S15E 3M4OE
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3HKZ H;  1WCM E;  3GTG E;  2Y0S H;  1TWG E;  3S17 E;  5C4X E;  4A3D E;  3S1Q E;  4AYB H;  4C3H E;  4C3I E;  5IP7 E;  2JA8 E;  4BY1 E;  3CQZ E;  3S2H E;  2E2H E;  2WAQ H;  3HOV E;  3I4N E;  1R9T E;  5C44 E;  5FJ8 E;  2JA6 E;  1TWC E;  3PO2 E;  4BBS E;  4X6A E;  5FLM E;  2E2I E;  2NVX E;  3GTL E;  4A93 E;  1SFO E;  3K7A E;  4A3F E;  1K83 E;  3GTO E;  3S1M E;  2NVT E;  5M3M E;  4Y7N E;  3RZO E;  4QIW H;  5M3F E;  4A3E E;  5M5W E;  5C4J E;  3HOW E;  3HOX E;  3GTM E;  1I50 E;  3GTQ E;  2NVQ E;  2JA7 E;  3H3V F;  1Y1V E;  2VUM E;  5M5X E;  2YU9 E;  2B63 E;  1EIK A;  4C3J E;  3GTJ E;  3GTK E;  4A3B E;  5IYB E;  1TWA E;  4A3J E;  2JA5 E;  5M5Y E;  3S1R E;  2WB1 H;  3PO3 E;  2R93 E;  2E2J E;  1TWH E;  3I4M E;  3S1N E;  4Y52 E;  2R92 E;  3M3Y E;  4BXX E;  4A3C E;  4BBR E;  4A3G E;  4A3M E;  3FKI E;  5C3E E;  1TWF E;  1Y1W E;  3HOU E;  3S14 E;  1I6H E;  4A3I E;  1I3Q E;  5IYC E;  3HOZ E;  5IYD E;  4A3L E;  3S16 E;  2NVY E;  3H0G E;  2PMZ H;  3GTP E;  1DZF A;  2R7Z E;  4A3K E;  3S2D E;  5IP9 E;  3RZD E;  3HOY E;  4BY7 E;  4C2M E;  3S15 E;  3M4O E; 
#chains in the Genus database with same CATH topology
 3HKZ H;  4A3G F;  3PO3 F;  1WCM E;  4A3M F;  3GTG E;  3FKI F;  5C3E F;  2Y0S H;  1TWF F;  1Y1W F;  4ZH4 E;  3HOU F;  3S14 F;  1TWG E;  3S17 E;  5C4X E;  4A3D E;  3S17 F;  3EQL E;  1I6H F;  4A3I F;  3S1Q E;  1I3Q F;  4AYB H;  4C3H E;  5IYC F;  3HOZ F;  4C3I E;  5IP7 E;  2JA8 E;  5IYD F;  3DXJ E;  2JA8 F;  4A3L F;  3S16 F;  4BY1 E;  1ZYR E;  1YNJ K;  1SMY E;  2NVY F;  3H0G F;  4LK0 E;  4XSZ E;  3CQZ E;  3S2H E;  2E2H E;  2WAQ H;  3GTP F;  3HOV E;  3I4N E;  1R9T E;  5C44 E;  2BE5 E;  2PMZ K;  4A3K F;  5IP9 F;  1R9T F;  2R7Z F;  3S2D F;  5FJ8 E;  2JA6 E;  1TWC E;  2WAQ K;  3PO2 E;  4BBS E;  3RZD F;  2Y0S I;  4BY7 F;  3HOY F;  4C2M F;  4X6A E;  3M4O F;  3S15 F;  4Q5S E;  5FLM E;  2E2I E;  2NVX E;  3GTL E;  4A93 E;  1WCM F;  3HKZ K;  5D4C E;  3GTG F;  1SFO E;  3K7A E;  4A3F E;  1K83 E;  3GTO E;  1IW7 E;  3S1M E;  5D4D E;  3H3V G;  2NVT E;  5M3M E;  4Y7N E;  3RZO E;  1TWG F;  4A3D F;  5M3M F;  5C4X F;  3RZO F;  4JK1 E;  4MEY E;  4G7O E;  4QIW H;  3S1Q F;  5M3F E;  4C3H F;  4A3E E;  5M5W E;  5C4J E;  4MQ9 E;  3HOW E;  4AYB K;  4C3I F;  4QIW K;  5IP7 F;  4LLG E;  3HOX E;  3GTM E;  4BY1 F;  1I50 E;  3GTQ E;  2A68 E;  2NVQ E;  3CQZ F;  3S2H F;  2E2H F;  2JA7 E;  2PPB E;  3HOV F;  3I4N F;  5C44 F;  2R93 F;  4KN4 E;  4XSX E;  3H3V F;  4Q4Z E;  5FJ8 F;  2JA6 F;  1TWC F;  3PO2 F;  1Y1V E;  4BBS F;  5E17 E;  2VUM E;  4X6A F;  5M5X E;  5TMC E;  5FLM F;  2YU9 E;  2E2I F;  2B63 E;  3WOD E;  4G7Z E;  4XLN E;  2NVX F;  2WB1 I;  3GTL F;  4A93 F;  4C3J E;  1EIK A;  2A6H E;  5IPL E;  3GTJ E;  3GTK E;  3K7A F;  4A3F F;  1K83 F;  1SFO F;  3GTO F;  4A3B E;  5IYB E;  3S1M F;  1I6V E;  2NVT F;  1TWA E;  4A3J E;  2JA5 E;  4Y7N F;  5M5Y E;  3S1R E;  2WB1 H;  3PO3 E;  4OIO E;  2R93 E;  2E2J E;  3S1R F;  5M3F F;  1TWH E;  4A3E F;  5M5W F;  3I4M E;  5C4J F;  4YFX E;  3S1N E;  3HOW F;  4Y52 E;  1QKL A;  3HOX F;  2R92 E;  3M3Y E;  4BXX E;  2A69 E;  4YFN E;  3GTM F;  4BXX F;  1I50 F;  4A3C E;  3GTQ F;  4GZY E;  2NVQ F;  4BBR E;  4A3G E;  2JA7 F;  4A3M E;  3FKI E;  5C3E E;  1HQM E;  1TWF E;  1Y1V F;  4G7H E;  1Y1W E;  4LJZ E;  3HOU E;  2A6E E;  3S14 E;  2VUM F;  5M5X F;  4YG2 E;  2YU9 F;  1I6H E;  4A3I E;  5TMF E;  1I3Q E;  2B63 F;  5IYC E;  4C3J F;  3HOZ E;  5D4E E;  5IYD E;  3GTJ F;  3GTK F;  4A3L E;  4YFK E;  4A3B F;  3S16 E;  4OIQ E;  5IYB F;  4MEX E;  2NVY E;  3H0G E;  1TWA F;  4A3J F;  2JA5 F;  2PMZ H;  5M5Y F;  2KRX A;  4LK1 E;  3GTP E;  4KMU E;  1YNN K;  1DZF A;  5BYH E;  5E18 E;  2E2J F;  2R7Z E;  2CW0 E;  4A3K E;  3S2D E;  5IP9 E;  1TWH F;  2O5I E;  3I4M F;  4XLP E;  3S1N F;  2O5J E;  3RZD E;  3HOY E;  4BY7 E;  4Y52 F;  4C2M E;  2R92 F;  3M3Y F;  4OIP E;  3S15 E;  3M4O E;  4OIR E;  4A3C F;  4OIN E;  4KN7 E;  4BBR F; 
#chains in the Genus database with same CATH homology
 3HKZ H;  1WCM E;  3GTG E;  2Y0S H;  1TWG E;  3S17 E;  5C4X E;  4A3D E;  3S1Q E;  4AYB H;  4C3H E;  4C3I E;  5IP7 E;  2JA8 E;  4BY1 E;  3CQZ E;  3S2H E;  2E2H E;  2WAQ H;  3HOV E;  3I4N E;  1R9T E;  5C44 E;  5FJ8 E;  2JA6 E;  1TWC E;  3PO2 E;  4BBS E;  4X6A E;  5FLM E;  2E2I E;  2NVX E;  3GTL E;  4A93 E;  1SFO E;  3K7A E;  4A3F E;  1K83 E;  3GTO E;  3S1M E;  2NVT E;  5M3M E;  4Y7N E;  3RZO E;  4QIW H;  5M3F E;  4A3E E;  5M5W E;  5C4J E;  3HOW E;  3HOX E;  3GTM E;  1I50 E;  3GTQ E;  2NVQ E;  2JA7 E;  3H3V F;  1Y1V E;  2VUM E;  5M5X E;  2YU9 E;  2B63 E;  1EIK A;  4C3J E;  3GTJ E;  3GTK E;  4A3B E;  5IYB E;  1TWA E;  4A3J E;  2JA5 E;  5M5Y E;  3S1R E;  2WB1 H;  3PO3 E;  2R93 E;  2E2J E;  1TWH E;  3I4M E;  3S1N E;  4Y52 E;  2R92 E;  3M3Y E;  4BXX E;  4A3C E;  4BBR E;  4A3G E;  4A3M E;  3FKI E;  5C3E E;  1TWF E;  1Y1W E;  3HOU E;  3S14 E;  1I6H E;  4A3I E;  1I3Q E;  5IYC E;  3HOZ E;  5IYD E;  4A3L E;  3S16 E;  2NVY E;  3H0G E;  2PMZ H;  3GTP E;  1DZF A;  2R7Z E;  4A3K E;  3S2D E;  5IP9 E;  3RZD E;  3HOY E;  4BY7 E;  4C2M E;  3S15 E;  3M4O E; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...