4G7HE

Crystal structure of thermus thermophilus transcription initiation complex
Total Genus 25
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
25
sequence length
94
structure length
94
Chain Sequence
AEPGIDKLFGMVDSKYRLTVVVAKRAQQLLRHGFKNTVLEPEERPKMQTLEGLFDDPNAVTWAMKELLTGRLVFGENLVPEDRLQKEMERLYPV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of transcription initiation.
pubmed doi rcsb
molecule tags Transcription, transferase/dna
source organism Thermus thermophilus
molecule keywords DNA-directed RNA polymerase subunit alpha
total genus 25
structure length 94
sequence length 94
chains with identical sequence O
ec nomenclature ec 2.7.7.6: DNA-directed RNA polymerase.
pdb deposition date 2012-07-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF01192 RNA_pol_Rpb6 RNA polymerase Rpb6
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.940.10 Alpha Beta Alpha-Beta Complex Eukaryotic RPB6 RNA polymerase subunit Eukaryotic RPB6 RNA polymerase subunit 4g7hE00
1TWAF 4A3GF 4LK1E 4C3JF 2A6EE 4OIOE 5BYHE 1SFOF 2WAQK 3HKZK 4XLNE 5M3FF 3RZOF 3FKIF 1SMYE 1TWCF 3HOYF 5C3EF 2BE5E 2NVQF 2WB1I 4KMUE 4A3FF 4AYBK 5M3MF 2R92F 3HOWF 2NVYF 3S2HF 1K83F 2A6HE 2JA5F 1WCMF 3DXJE 4Y52F 3PO2F 5D4CE 5C4JF 5IP9F 5IP7F 5IYCF 4A3EF 3HOUF 5D4EE 2JA6F 4X6AF 3GTMF 4LJZE 1R9TF 5C44F 2O5JE 2A68E 4KN4E 4XLPE 4A3DF 4Y7NF 5E18E 3I4MF 4MEXE 4YFXE 3M4OF 3S1RF 3HOVF 3CQZF 3K7AF 3H0GF 5IYDF 4C3IF 2R93F 5IPLE 3GTJF 3GTOF 2JA7F 2B63F 2E2IF 4LLGE 3H3VG 4C2MF 3EQLE 1QKLA 3WODE 1IW7E 4A3CF 4OIQE 1I6VE 4A3IF 2PMZK 1TWHF 5D4DE 2A69E 2R7ZF 4C3HF 4ZH4E 3HOXF 4Q5SE 3S2DF 1TWFF 2NVXF 2O5IE 4GZYE 4A3KF 4OINE 5M5YF 4A3JF 4MEYE 3GTKF 4A93F 4BY1F 4YFKE 5FJ8F 2NVTF 1I3QF 4XSZE 4YG2E 4YFNE 5FLMF 1HQME 4G7ZE 2VUMF 4Q4ZE 3S14F 1ZYRE 2JA8F 3M3YF 3GTQF 1I6HF 5IYBF 3S16F 2CW0E 3S1QF 5M5WF 5TMCE 3S1NF 4KN7E 1I50F 4JK1E 4OIPE 3PO3F 4BBSF 3I4NF 4MQ9E 4A3BF 2YU9F 1Y1WF 1YNJK 2E2HF 5M5XF 3GTPF 2PPBE 4LK0E 2Y0SI 4XSXE 4A3MF 5E17E 3GTGF 3S15F 5C4XF 3RZDF 4G7HE 3S17F 1TWGF 1Y1VF 3GTLF 3HOZF 4BY7F 5TMFE 4A3LF 4BXXF 4BBRF 4G7OE 3S1MF 1YNNK 2E2JF 4OIRE
chains in the Genus database with same CATH superfamily
2R7ZE 1TWAF 4C3HE 4A3GF 4LK1E 4C3JF 2A6EE 3GTME 3HOXE 4OIOE 3S2DE 1TWFE 1DZFA 2NVXE 5BYHE 4A3KE 1SFOF 2WAQK 3HKZK 4XLNE 5M5YE 5M3FF 4A3JE 3RZOF 3GTKE 4BY1E 3FKIF 3I4ME 1SMYE 1TWCF 3HOYF 5FJ8E 5C3EF 3K7AE 2BE5E 2NVQF 2NVTE 1I3QE 2WB1I 4KMUE 5IYDE 4AYBK 5M3MF 4A3FF 2R92F 3HOWF 2NVYF 5FLME 2VUME 3S2HF 1K83F 2A6HE 2JA5F 1WCMF 3S14E 3DXJE 4Y52F 2JA8E 3PO2F 3M3YE 5D4CE 5C4JF 3GTQE 5IYBE 1I6HE 3S16E 5IP9F 5IP7F 5IYCF 5M5WE 4A3EF 3S1QE 2KRXA 3HOUF 3S1NE 5D4EE 2JA6F 4X6AF 3GTMF 4LJZE 1I50E 1R9TF 5C44F 3PO3E 4BBSE 2O5JE 1EIKA 3I4NE 2A68E 4KN4E 4A3BE 2YU9E 4XLPE 4A3DF 1Y1WE 4Y7NF 2E2HE 5E18E 5M5XE 3GTPE 3I4MF 4MEXE 4YFXE 3M4OF 3S1RF 3HOVF 3CQZF 3K7AF 4A93E 3H0GF 5IYDF 4C3IF 2R93F 5IPLE 4A3ME 3GTJF 2Y0SH 3GTGE 3S15E 4QIWH 5C4XE 3GTOF 3RZDE 2JA7F 2B63F 2E2IF 3S17E 4LLGE 3H3VG 1TWGE 4C2MF 3EQLE 1Y1VE 3GTLE 3HOZE 1QKLA 3WODE 4A3LE 1IW7E 4BY7E 4A3CF 4BXXE 4BBRE 4OIQE 3S1ME 1I6VE 4A3IF 2E2JE 2PMZK 1TWHF 5D4DE 2A69E 2R7ZF 4C3HF 1TWAE 4ZH4E 4A3GE 4C3JE 3HOXF 4Q5SE 3S2DF 1TWFF 3HKZH 2NVXF 2O5IE 4GZYE 4A3KF 1SFOE 4OINE 5M5YF 5M3FE 4A3JF 4MEYE 3GTKF 4A93F 4BY1F 3FKIE 4YFKE 4AYBH 1TWCE 5FJ8F 3HOYE 5C3EE 3H3VF 2NVTF 1I3QF 2NVQE 4A3FE 4XSZE 2R92E 4YG2E 4YFNE 5FLMF 1HQME 2NVYE 4G7ZE 2VUMF 3HOWE 1K83E 2WB1H 4Q4ZE 2JA5E 1WCME 3S14F 1ZYRE 2JA8F 4Y52E 3PO2E 3M3YF 3GTQF 1I6HF 5IYBF 5C4JE 3S16F 2CW0E 3S1QF 5IYCE 5IP9E 5IP7E 5TMCE 5M5WF 4A3EE 3HOUE 4KN7E 3S1NF 2JA6E 4X6AE 1I50F 4JK1E 4OIPE 1R9TE 5C44E 3PO3F 4BBSF 3I4NF 4MQ9E 4A3BF 2YU9F 2WAQH 1Y1WF 4A3DE 1YNJK 2E2HF 4Y7NE 5M5XF 3GTPF 2PPBE 3RZOE 3M4OE 4LK0E 3S1RE 2Y0SI 3HOVE 3CQZE 3H0GE 4XSXE 4C3IE 2R93E 4A3MF 5E17E 3GTGF 3GTJE 3S15F 5C4XF 3RZDF 3GTOE 2JA7E 5M3ME 4G7HE 2B63E 2E2IE 3S17F 3S2HE 4QIWK 1TWGF 4C2ME 1Y1VF 3GTLF 3HOZF 4BY7F 5TMFE 4A3LF 4BXXF 4BBRF 4A3CE 4G7OE 2PMZH 3S1MF 1YNNK 2E2JF 4A3IE 4OIRE 1TWHE
chains in the Genus database with same CATH topology
1TWAF 4A3GF 4LK1E 4C3JF 2A6EE 4OIOE 5BYHE 1SFOF 2WAQK 3HKZK 4XLNE 5M3FF 3RZOF 3FKIF 1SMYE 1TWCF 3HOYF 5C3EF 2BE5E 2NVQF 2WB1I 4KMUE 4A3FF 4AYBK 5M3MF 2R92F 3HOWF 2NVYF 3S2HF 1K83F 2A6HE 2JA5F 1WCMF 3DXJE 4Y52F 3PO2F 5D4CE 5C4JF 5IP9F 5IP7F 5IYCF 4A3EF 2KRXA 3HOUF 5D4EE 2JA6F 4X6AF 3GTMF 4LJZE 1R9TF 5C44F 2O5JE 2A68E 4KN4E 4XLPE 4A3DF 4Y7NF 5E18E 3I4MF 4MEXE 4YFXE 3M4OF 3S1RF 3HOVF 3CQZF 3K7AF 3H0GF 5IYDF 4C3IF 2R93F 5IPLE 3GTJF 3GTOF 2JA7F 2B63F 2E2IF 4LLGE 3H3VG 4C2MF 3EQLE 1QKLA 3WODE 1IW7E 4A3CF 4OIQE 1I6VE 4A3IF 2PMZK 1TWHF 5D4DE 2A69E 2R7ZF 4C3HF 4ZH4E 3HOXF 4Q5SE 3S2DF 1TWFF 2NVXF 2O5IE 4GZYE 4A3KF 4OINE 5M5YF 4A3JF 4MEYE 3GTKF 4A93F 4BY1F 4YFKE 5FJ8F 2NVTF 1I3QF 4XSZE 4YG2E 4YFNE 5FLMF 1HQME 4G7ZE 2VUMF 4Q4ZE 3S14F 1ZYRE 2JA8F 3M3YF 3GTQF 1I6HF 5IYBF 3S16F 2CW0E 3S1QF 5M5WF 5TMCE 3S1NF 4KN7E 1I50F 4JK1E 4OIPE 3PO3F 4BBSF 3I4NF 4MQ9E 4A3BF 2YU9F 1Y1WF 1YNJK 2E2HF 5M5XF 3GTPF 2PPBE 4LK0E 2Y0SI 4XSXE 4A3MF 5E17E 3GTGF 3S15F 5C4XF 3RZDF 4G7HE 3S17F 4QIWK 1TWGF 1Y1VF 3GTLF 3HOZF 4BY7F 5TMFE 4A3LF 4BXXF 4BBRF 4G7OE 3S1MF 1YNNK 2E2JF 4OIRE
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1TWA F;  4A3G F;  4LK1 E;  4C3J F;  2A6E E;  4OIO E;  5BYH E;  1SFO F;  2WAQ K;  3HKZ K;  4XLN E;  5M3F F;  3RZO F;  3FKI F;  1SMY E;  1TWC F;  3HOY F;  5C3E F;  2BE5 E;  2NVQ F;  2WB1 I;  4KMU E;  4A3F F;  4AYB K;  5M3M F;  2R92 F;  3HOW F;  2NVY F;  3S2H F;  1K83 F;  2A6H E;  2JA5 F;  1WCM F;  3DXJ E;  4Y52 F;  3PO2 F;  5D4C E;  5C4J F;  5IP9 F;  5IP7 F;  5IYC F;  4A3E F;  3HOU F;  5D4E E;  2JA6 F;  4X6A F;  3GTM F;  4LJZ E;  1R9T F;  5C44 F;  2O5J E;  2A68 E;  4KN4 E;  4XLP E;  4A3D F;  4Y7N F;  5E18 E;  3I4M F;  4MEX E;  4YFX E;  3M4O F;  3S1R F;  3HOV F;  3CQZ F;  3K7A F;  3H0G F;  5IYD F;  4C3I F;  2R93 F;  5IPL E;  3GTJ F;  3GTO F;  2JA7 F;  2B63 F;  2E2I F;  4LLG E;  3H3V G;  4C2M F;  3EQL E;  1QKL A;  3WOD E;  1IW7 E;  4A3C F;  4OIQ E;  1I6V E;  4A3I F;  2PMZ K;  1TWH F;  5D4D E;  2A69 E;  2R7Z F;  4C3H F;  4ZH4 E;  3HOX F;  4Q5S E;  3S2D F;  1TWF F;  2NVX F;  2O5I E;  4GZY E;  4A3K F;  4OIN E;  5M5Y F;  4A3J F;  4MEY E;  3GTK F;  4A93 F;  4BY1 F;  4YFK E;  5FJ8 F;  2NVT F;  1I3Q F;  4XSZ E;  4YG2 E;  4YFN E;  5FLM F;  1HQM E;  4G7Z E;  2VUM F;  4Q4Z E;  3S14 F;  1ZYR E;  2JA8 F;  3M3Y F;  3GTQ F;  1I6H F;  5IYB F;  3S16 F;  2CW0 E;  3S1Q F;  5M5W F;  5TMC E;  3S1N F;  4KN7 E;  1I50 F;  4JK1 E;  4OIP E;  3PO3 F;  4BBS F;  3I4N F;  4MQ9 E;  4A3B F;  2YU9 F;  1Y1W F;  1YNJ K;  2E2H F;  5M5X F;  3GTP F;  2PPB E;  4LK0 E;  2Y0S I;  4XSX E;  4A3M F;  5E17 E;  3GTG F;  3S15 F;  5C4X F;  3RZD F;  4G7H E;  3S17 F;  1TWG F;  1Y1V F;  3GTL F;  3HOZ F;  4BY7 F;  5TMF E;  4A3L F;  4BXX F;  4BBR F;  4G7O E;  3S1M F;  1YNN K;  2E2J F;  4OIR E; 
#chains in the Genus database with same CATH topology
 2R7Z E;  1TWA F;  4C3H E;  4A3G F;  4LK1 E;  4C3J F;  2A6E E;  3GTM E;  3HOX E;  4OIO E;  3S2D E;  1TWF E;  1DZF A;  2NVX E;  5BYH E;  4A3K E;  1SFO F;  2WAQ K;  3HKZ K;  4XLN E;  5M5Y E;  5M3F F;  4A3J E;  3RZO F;  3GTK E;  4BY1 E;  3FKI F;  3I4M E;  1SMY E;  1TWC F;  3HOY F;  5FJ8 E;  5C3E F;  3K7A E;  2BE5 E;  2NVQ F;  2NVT E;  1I3Q E;  2WB1 I;  4KMU E;  5IYD E;  4AYB K;  5M3M F;  4A3F F;  2R92 F;  3HOW F;  2NVY F;  5FLM E;  2VUM E;  3S2H F;  1K83 F;  2A6H E;  2JA5 F;  1WCM F;  3S14 E;  3DXJ E;  4Y52 F;  2JA8 E;  3PO2 F;  3M3Y E;  5D4C E;  5C4J F;  3GTQ E;  5IYB E;  1I6H E;  3S16 E;  5IP9 F;  5IP7 F;  5IYC F;  5M5W E;  4A3E F;  3S1Q E;  2KRX A;  3HOU F;  3S1N E;  5D4E E;  2JA6 F;  4X6A F;  3GTM F;  4LJZ E;  1I50 E;  1R9T F;  5C44 F;  3PO3 E;  4BBS E;  2O5J E;  1EIK A;  3I4N E;  2A68 E;  4KN4 E;  4A3B E;  2YU9 E;  4XLP E;  4A3D F;  1Y1W E;  4Y7N F;  2E2H E;  5E18 E;  5M5X E;  3GTP E;  3I4M F;  4MEX E;  4YFX E;  3M4O F;  3S1R F;  3HOV F;  3CQZ F;  3K7A F;  4A93 E;  3H0G F;  5IYD F;  4C3I F;  2R93 F;  5IPL E;  4A3M E;  3GTJ F;  2Y0S H;  3GTG E;  3S15 E;  4QIW H;  5C4X E;  3GTO F;  3RZD E;  2JA7 F;  2B63 F;  2E2I F;  3S17 E;  4LLG E;  3H3V G;  1TWG E;  4C2M F;  3EQL E;  1Y1V E;  3GTL E;  3HOZ E;  1QKL A;  3WOD E;  4A3L E;  1IW7 E;  4BY7 E;  4A3C F;  4BXX E;  4BBR E;  4OIQ E;  3S1M E;  1I6V E;  4A3I F;  2E2J E;  2PMZ K;  1TWH F;  5D4D E;  2A69 E;  2R7Z F;  4C3H F;  1TWA E;  4ZH4 E;  4A3G E;  4C3J E;  3HOX F;  4Q5S E;  3S2D F;  1TWF F;  3HKZ H;  2NVX F;  2O5I E;  4GZY E;  4A3K F;  1SFO E;  4OIN E;  5M5Y F;  5M3F E;  4A3J F;  4MEY E;  3GTK F;  4A93 F;  4BY1 F;  3FKI E;  4YFK E;  4AYB H;  1TWC E;  5FJ8 F;  3HOY E;  5C3E E;  3H3V F;  2NVT F;  1I3Q F;  2NVQ E;  4A3F E;  4XSZ E;  2R92 E;  4YG2 E;  4YFN E;  5FLM F;  1HQM E;  2NVY E;  4G7Z E;  2VUM F;  3HOW E;  1K83 E;  2WB1 H;  4Q4Z E;  2JA5 E;  1WCM E;  3S14 F;  1ZYR E;  2JA8 F;  4Y52 E;  3PO2 E;  3M3Y F;  3GTQ F;  1I6H F;  5IYB F;  5C4J E;  3S16 F;  2CW0 E;  3S1Q F;  5IYC E;  5IP9 E;  5IP7 E;  5TMC E;  5M5W F;  4A3E E;  3HOU E;  4KN7 E;  3S1N F;  2JA6 E;  4X6A E;  1I50 F;  4JK1 E;  4OIP E;  1R9T E;  5C44 E;  3PO3 F;  4BBS F;  3I4N F;  4MQ9 E;  4A3B F;  2YU9 F;  2WAQ H;  1Y1W F;  4A3D E;  1YNJ K;  2E2H F;  4Y7N E;  5M5X F;  3GTP F;  2PPB E;  3RZO E;  3M4O E;  4LK0 E;  3S1R E;  2Y0S I;  3HOV E;  3CQZ E;  3H0G E;  4XSX E;  4C3I E;  2R93 E;  4A3M F;  5E17 E;  3GTG F;  3GTJ E;  3S15 F;  5C4X F;  3RZD F;  3GTO E;  2JA7 E;  5M3M E;  4G7H E;  2B63 E;  2E2I E;  3S17 F;  3S2H E;  4QIW K;  1TWG F;  4C2M E;  1Y1V F;  3GTL F;  3HOZ F;  4BY7 F;  5TMF E;  4A3L F;  4BXX F;  4BBR F;  4A3C E;  4G7O E;  2PMZ H;  3S1M F;  1YNN K;  2E2J F;  4A3I E;  4OIR E;  1TWH E; 
#chains in the Genus database with same CATH homology
 1TWA F;  4A3G F;  4LK1 E;  4C3J F;  2A6E E;  4OIO E;  5BYH E;  1SFO F;  2WAQ K;  3HKZ K;  4XLN E;  5M3F F;  3RZO F;  3FKI F;  1SMY E;  1TWC F;  3HOY F;  5C3E F;  2BE5 E;  2NVQ F;  2WB1 I;  4KMU E;  4A3F F;  4AYB K;  5M3M F;  2R92 F;  3HOW F;  2NVY F;  3S2H F;  1K83 F;  2A6H E;  2JA5 F;  1WCM F;  3DXJ E;  4Y52 F;  3PO2 F;  5D4C E;  5C4J F;  5IP9 F;  5IP7 F;  5IYC F;  4A3E F;  2KRX A;  3HOU F;  5D4E E;  2JA6 F;  4X6A F;  3GTM F;  4LJZ E;  1R9T F;  5C44 F;  2O5J E;  2A68 E;  4KN4 E;  4XLP E;  4A3D F;  4Y7N F;  5E18 E;  3I4M F;  4MEX E;  4YFX E;  3M4O F;  3S1R F;  3HOV F;  3CQZ F;  3K7A F;  3H0G F;  5IYD F;  4C3I F;  2R93 F;  5IPL E;  3GTJ F;  3GTO F;  2JA7 F;  2B63 F;  2E2I F;  4LLG E;  3H3V G;  4C2M F;  3EQL E;  1QKL A;  3WOD E;  1IW7 E;  4A3C F;  4OIQ E;  1I6V E;  4A3I F;  2PMZ K;  1TWH F;  5D4D E;  2A69 E;  2R7Z F;  4C3H F;  4ZH4 E;  3HOX F;  4Q5S E;  3S2D F;  1TWF F;  2NVX F;  2O5I E;  4GZY E;  4A3K F;  4OIN E;  5M5Y F;  4A3J F;  4MEY E;  3GTK F;  4A93 F;  4BY1 F;  4YFK E;  5FJ8 F;  2NVT F;  1I3Q F;  4XSZ E;  4YG2 E;  4YFN E;  5FLM F;  1HQM E;  4G7Z E;  2VUM F;  4Q4Z E;  3S14 F;  1ZYR E;  2JA8 F;  3M3Y F;  3GTQ F;  1I6H F;  5IYB F;  3S16 F;  2CW0 E;  3S1Q F;  5M5W F;  5TMC E;  3S1N F;  4KN7 E;  1I50 F;  4JK1 E;  4OIP E;  3PO3 F;  4BBS F;  3I4N F;  4MQ9 E;  4A3B F;  2YU9 F;  1Y1W F;  1YNJ K;  2E2H F;  5M5X F;  3GTP F;  2PPB E;  4LK0 E;  2Y0S I;  4XSX E;  4A3M F;  5E17 E;  3GTG F;  3S15 F;  5C4X F;  3RZD F;  4G7H E;  3S17 F;  4QIW K;  1TWG F;  1Y1V F;  3GTL F;  3HOZ F;  4BY7 F;  5TMF E;  4A3L F;  4BXX F;  4BBR F;  4G7O E;  3S1M F;  1YNN K;  2E2J F;  4OIR E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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