4HLGC

Crystal structure of tankyrase 2 in complex with 3'-hydroxyflavone
Total Genus 1
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
1
sequence length
47
structure length
47
Chain Sequence
MAHSPPGHHSVTGRPSVNGLALAEYVIYRGEQAYPEYLITYQIMRPE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Screening and structural analysis of flavones inhibiting tankyrases.
pubmed doi rcsb
molecule tags Transferase
source organism Homo sapiens
molecule keywords Tankyrase-2
total genus 1
structure length 47
sequence length 47
chains with identical sequence D
ec nomenclature ec 2.4.2.30: NAD(+) ADP-ribosyltransferase.
pdb deposition date 2012-10-17
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1620.50 Alpha Beta 3-Layer(aba) Sandwich YefM-like fold YefM-like fold 4hlgC00
4L0TC 4L2GC 4L33C 5ADRB 5ADQB 4L31C 4UI4C 4L09C 4L10C 4HKNC 5ADSB 4L0IC 4HKIC 4HLMC 4L0BC 4HLHC 4UI3C 4UI7C 4UVPB 5C5RC 4KZUC 4KZLC 4L2FC 4L0VC 5FPFC 4UI5C 4HLGC 4HLKC 5C5PC 4HLFC 4L0SC 4L2KC 5ADTB 4L34C 5C5QC 4UI6C 4HL5C 4L32C 4HMHC 4UI8C 4KZQC 4HKKB
chains in the Genus database with same CATH superfamily
3K33B 3D55A 4L0TC 4L2GC 4L33C 4ZM2A 3OEIE 5ADRB 2ZIXB 5ADQB 4L31C 4ZLXA 4UI4C 3HS2A 4L09C 3HRYA 3K6QA 4HKNC 4L10C 5ADSB 3G5OA 3OEIA 4L0IC 4HKIC 4HLMC 3KH2E 4L0BC 4HLHC 4UI3C 4UI7C 4UVPB 5C5RC 4KZUC 4KZLC 4L2FC 4L0VC 5FPFC 4UI5C 3HJ6A 4HLGC 4HLKC 5C5PC 4HLFC 2ODKA 4L0SC 4L2KC 5ADTB 4L34C 5C5QC 4ZM0A 4UI6C 2A6QA 4HL5C 4L32C 4HMHC 4UI8C 4KZQC 3CTOA 4HKKB
chains in the Genus database with same CATH topology
4L0TC 4L2GC 4L33C 5ADRB 2ZIXB 5ADQB 4L31C 4UI4C 4L09C 4L10C 4HKNC 5ADSB 4L0IC 4HKIC 4HLMC 4L0BC 4HLHC 4UI3C 4UI7C 4UVPB 5C5RC 4KZUC 4KZLC 4L2FC 4L0VC 5FPFC 4UI5C 3HJ6A 4HLGC 4HLKC 5C5PC 4HLFC 4L0SC 4L2KC 5ADTB 4L34C 5C5QC 4UI6C 4HL5C 4L32C 4HMHC 4UI8C 4KZQC 4HKKB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4L0T C;  4L2G C;  4L33 C;  5ADR B;  5ADQ B;  4L31 C;  4UI4 C;  4L09 C;  4L10 C;  4HKN C;  5ADS B;  4L0I C;  4HKI C;  4HLM C;  4L0B C;  4HLH C;  4UI3 C;  4UI7 C;  4UVP B;  5C5R C;  4KZU C;  4KZL C;  4L2F C;  4L0V C;  5FPF C;  4UI5 C;  4HLG C;  4HLK C;  5C5P C;  4HLF C;  4L0S C;  4L2K C;  5ADT B;  4L34 C;  5C5Q C;  4UI6 C;  4HL5 C;  4L32 C;  4HMH C;  4UI8 C;  4KZQ C;  4HKK B; 
#chains in the Genus database with same CATH topology
 3K33 B;  3D55 A;  4L0T C;  4L2G C;  4L33 C;  4ZM2 A;  3OEI E;  5ADR B;  2ZIX B;  5ADQ B;  4L31 C;  4ZLX A;  4UI4 C;  3HS2 A;  4L09 C;  3HRY A;  3K6Q A;  4HKN C;  4L10 C;  5ADS B;  3G5O A;  3OEI A;  4L0I C;  4HKI C;  4HLM C;  3KH2 E;  4L0B C;  4HLH C;  4UI3 C;  4UI7 C;  4UVP B;  5C5R C;  4KZU C;  4KZL C;  4L2F C;  4L0V C;  5FPF C;  4UI5 C;  3HJ6 A;  4HLG C;  4HLK C;  5C5P C;  4HLF C;  2ODK A;  4L0S C;  4L2K C;  5ADT B;  4L34 C;  5C5Q C;  4ZM0 A;  4UI6 C;  2A6Q A;  4HL5 C;  4L32 C;  4HMH C;  4UI8 C;  4KZQ C;  3CTO A;  4HKK B; 
#chains in the Genus database with same CATH homology
 4L0T C;  4L2G C;  4L33 C;  5ADR B;  2ZIX B;  5ADQ B;  4L31 C;  4UI4 C;  4L09 C;  4L10 C;  4HKN C;  5ADS B;  4L0I C;  4HKI C;  4HLM C;  4L0B C;  4HLH C;  4UI3 C;  4UI7 C;  4UVP B;  5C5R C;  4KZU C;  4KZL C;  4L2F C;  4L0V C;  5FPF C;  4UI5 C;  3HJ6 A;  4HLG C;  4HLK C;  5C5P C;  4HLF C;  4L0S C;  4L2K C;  5ADT B;  4L34 C;  5C5Q C;  4UI6 C;  4HL5 C;  4L32 C;  4HMH C;  4UI8 C;  4KZQ C;  4HKK B; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...