4HLGC

Crystal structure of tankyrase 2 in complex with 3'-hydroxyflavone
Total Genus 1
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
1
sequence length
47
structure length
47
Chain Sequence
MAHSPPGHHSVTGRPSVNGLALAEYVIYRGEQAYPEYLITYQIMRPE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Screening and structural analysis of flavones inhibiting tankyrases.
pubmed doi rcsb
molecule keywords Tankyrase-2
molecule tags Transferase
source organism Homo sapiens
total genus 1
structure length 47
sequence length 47
chains with identical sequence D
ec nomenclature ec 2.4.2.30: NAD(+) ADP-ribosyltransferase.
pdb deposition date 2012-10-17
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1620.50 Alpha Beta 3-Layer(aba) Sandwich YefM-like fold YefM-like fold 4hlgC00
4HLMC 5C5QC 4UVPB 4KZUC 4L10C 4HMHC 4HLFC 4L2FC 4L2KC 5ADQB 4L32C 4L0IC 4HLKC 5ADRB 4UI5C 4L09C 4L0TC 4UI3C 4HKKB 4KZQC 4L0BC 5ADTB 4UI4C 4UI8C 4L0VC 4HLHC 4HLGC 4L33C 4L34C 4L2GC 4UI7C 4UI6C 4HL5C 5C5RC 4L31C 4L0SC 5C5PC 5ADSB 4KZLC 4HKIC 5FPFC 4HKNC
chains in the Genus database with same CATH superfamily
4HLMC 5C5QC 4UVPB 4KZUC 4L10C 4HMHC 4HLFC 4L2FC 4L2KC 5ADQB 4L32C 4HLKC 4L0IC 5ADRB 4UI5C 4L09C 3D55A 4L0TC 4UI3C 4HKKB 4ZLXA 4KZQC 4L0BC 5ADTB 4UI4C 4UI8C 3G5OA 4L0VC 3CTOA 4ZM2A 4ZM0A 4HLHC 4HLGC 4L33C 4L34C 4L2GC 4UI7C 3K33B 4UI6C 4HL5C 2A6QA 4L31C 5C5RC 3HJ6A 2ODKA 2ZIXB 3HRYA 3HS2A 4L0SC 5C5PC 5ADSB 3K6QA 4KZLC 4HKIC 3OEIE 5FPFC 3OEIA 3KH2E 4HKNC
chains in the Genus database with same CATH topology
4HLMC 5C5QC 4UVPB 4KZUC 4L10C 4HMHC 4HLFC 4L2FC 4L2KC 5ADQB 4L32C 4L0IC 4HLKC 5ADRB 4UI5C 4L09C 4L0TC 4UI3C 4HKKB 4KZQC 4L0BC 5ADTB 4UI4C 4UI8C 4L0VC 4HLHC 4HLGC 4L33C 4L34C 4L2GC 4UI7C 4UI6C 4HL5C 5C5RC 4L31C 3HJ6A 2ZIXB 4L0SC 5C5PC 5ADSB 4KZLC 4HKIC 5FPFC 4HKNC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4HLM C;  5C5Q C;  4UVP B;  4KZU C;  4L10 C;  4HMH C;  4HLF C;  4L2F C;  4L2K C;  5ADQ B;  4L32 C;  4L0I C;  4HLK C;  5ADR B;  4UI5 C;  4L09 C;  4L0T C;  4UI3 C;  4HKK B;  4KZQ C;  4L0B C;  5ADT B;  4UI4 C;  4UI8 C;  4L0V C;  4HLH C;  4HLG C;  4L33 C;  4L34 C;  4L2G C;  4UI7 C;  4UI6 C;  4HL5 C;  5C5R C;  4L31 C;  4L0S C;  5C5P C;  5ADS B;  4KZL C;  4HKI C;  5FPF C;  4HKN C; 
#chains in the Genus database with same CATH topology
 4HLM C;  5C5Q C;  4UVP B;  4KZU C;  4L10 C;  4HMH C;  4HLF C;  4L2F C;  4L2K C;  5ADQ B;  4L32 C;  4HLK C;  4L0I C;  5ADR B;  4UI5 C;  4L09 C;  3D55 A;  4L0T C;  4UI3 C;  4HKK B;  4ZLX A;  4KZQ C;  4L0B C;  5ADT B;  4UI4 C;  4UI8 C;  3G5O A;  4L0V C;  3CTO A;  4ZM2 A;  4ZM0 A;  4HLH C;  4HLG C;  4L33 C;  4L34 C;  4L2G C;  4UI7 C;  3K33 B;  4UI6 C;  4HL5 C;  2A6Q A;  4L31 C;  5C5R C;  3HJ6 A;  2ODK A;  2ZIX B;  3HRY A;  3HS2 A;  4L0S C;  5C5P C;  5ADS B;  3K6Q A;  4KZL C;  4HKI C;  3OEI E;  5FPF C;  3OEI A;  3KH2 E;  4HKN C; 
#chains in the Genus database with same CATH homology
 4HLM C;  5C5Q C;  4UVP B;  4KZU C;  4L10 C;  4HMH C;  4HLF C;  4L2F C;  4L2K C;  5ADQ B;  4L32 C;  4L0I C;  4HLK C;  5ADR B;  4UI5 C;  4L09 C;  4L0T C;  4UI3 C;  4HKK B;  4KZQ C;  4L0B C;  5ADT B;  4UI4 C;  4UI8 C;  4L0V C;  4HLH C;  4HLG C;  4L33 C;  4L34 C;  4L2G C;  4UI7 C;  4UI6 C;  4HL5 C;  5C5R C;  4L31 C;  3HJ6 A;  2ZIX B;  4L0S C;  5C5P C;  5ADS B;  4KZL C;  4HKI C;  5FPF C;  4HKN C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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