4HMHC

Crystal structure of tankyrase 2 in complex with 7,3-dihydroxyflavone
Total Genus 1
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
1
sequence length
47
structure length
47
Chain Sequence
MAHSPPGHHSVTGRPSVNGLALAEYVIYRGEQAYPEYLITYQIMRPE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Screening and structural analysis of flavones inhibiting tankyrases.
pubmed doi rcsb
molecule keywords Tankyrase-2
molecule tags Transferase
source organism Homo sapiens
total genus 1
structure length 47
sequence length 47
ec nomenclature ec 2.4.2.30: NAD(+) ADP-ribosyltransferase.
pdb deposition date 2012-10-18
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1620.50 Alpha Beta 3-Layer(aba) Sandwich YefM-like fold YefM-like fold 4hmhC00
4HKKB 4L09C 4UVPB 4HLHC 5ADTB 4L0SC 5FPFC 4L32C 4HMHC 5C5QC 4HLGC 4L10C 4UI3C 4L31C 4L0IC 4L2KC 4HLKC 4L2GC 4HL5C 4L0TC 4HKNC 4KZQC 5ADRB 4L33C 4UI7C 4HLMC 5ADSB 4UI6C 4KZUC 4UI8C 4KZLC 5C5PC 4UI4C 5C5RC 5ADQB 4L0BC 4L0VC 4L2FC 4UI5C 4HKIC 4HLFC 4L34C
chains in the Genus database with same CATH superfamily
4HKKB 4L09C 4UVPB 4HLHC 5ADTB 4L0SC 5FPFC 4L32C 2A6QA 4HMHC 4ZLXA 5C5QC 4HLGC 4L10C 3HS2A 3HJ6A 3G5OA 4UI3C 4ZM0A 4L31C 4L0IC 3OEIE 4L2KC 3KH2E 4HLKC 4L2GC 4HL5C 4L0TC 4HKNC 4KZQC 5ADRB 3K33B 2ODKA 3CTOA 4L33C 4UI7C 4HLMC 5ADSB 4UI6C 4ZM2A 4KZUC 4UI8C 4KZLC 5C5PC 3OEIA 4UI4C 5C5RC 5ADQB 2ZIXB 3D55A 3K6QA 4L0BC 3HRYA 4L0VC 4L2FC 4UI5C 4HKIC 4HLFC 4L34C
chains in the Genus database with same CATH topology
4HKKB 4L09C 4UVPB 4HLHC 5ADTB 4L0SC 5FPFC 4L32C 4HMHC 5C5QC 4HLGC 4L10C 3HJ6A 4UI3C 4L31C 4L0IC 4L2KC 4HLKC 4L2GC 4HL5C 4L0TC 4HKNC 4KZQC 5ADRB 4L33C 4UI7C 4HLMC 5ADSB 4UI6C 4KZUC 4UI8C 4KZLC 5C5PC 4UI4C 5C5RC 5ADQB 2ZIXB 4L0BC 4L0VC 4L2FC 4UI5C 4HKIC 4HLFC 4L34C
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4HKK B;  4L09 C;  4UVP B;  4HLH C;  5ADT B;  4L0S C;  5FPF C;  4L32 C;  4HMH C;  5C5Q C;  4HLG C;  4L10 C;  4UI3 C;  4L31 C;  4L0I C;  4L2K C;  4HLK C;  4L2G C;  4HL5 C;  4L0T C;  4HKN C;  4KZQ C;  5ADR B;  4L33 C;  4UI7 C;  4HLM C;  5ADS B;  4UI6 C;  4KZU C;  4UI8 C;  4KZL C;  5C5P C;  4UI4 C;  5C5R C;  5ADQ B;  4L0B C;  4L0V C;  4L2F C;  4UI5 C;  4HKI C;  4HLF C;  4L34 C; 
#chains in the Genus database with same CATH topology
 4HKK B;  4L09 C;  4UVP B;  4HLH C;  5ADT B;  4L0S C;  5FPF C;  4L32 C;  2A6Q A;  4HMH C;  4ZLX A;  5C5Q C;  4HLG C;  4L10 C;  3HS2 A;  3HJ6 A;  3G5O A;  4UI3 C;  4ZM0 A;  4L31 C;  4L0I C;  3OEI E;  4L2K C;  3KH2 E;  4HLK C;  4L2G C;  4HL5 C;  4L0T C;  4HKN C;  4KZQ C;  5ADR B;  3K33 B;  2ODK A;  3CTO A;  4L33 C;  4UI7 C;  4HLM C;  5ADS B;  4UI6 C;  4ZM2 A;  4KZU C;  4UI8 C;  4KZL C;  5C5P C;  3OEI A;  4UI4 C;  5C5R C;  5ADQ B;  2ZIX B;  3D55 A;  3K6Q A;  4L0B C;  3HRY A;  4L0V C;  4L2F C;  4UI5 C;  4HKI C;  4HLF C;  4L34 C; 
#chains in the Genus database with same CATH homology
 4HKK B;  4L09 C;  4UVP B;  4HLH C;  5ADT B;  4L0S C;  5FPF C;  4L32 C;  4HMH C;  5C5Q C;  4HLG C;  4L10 C;  3HJ6 A;  4UI3 C;  4L31 C;  4L0I C;  4L2K C;  4HLK C;  4L2G C;  4HL5 C;  4L0T C;  4HKN C;  4KZQ C;  5ADR B;  4L33 C;  4UI7 C;  4HLM C;  5ADS B;  4UI6 C;  4KZU C;  4UI8 C;  4KZL C;  5C5P C;  4UI4 C;  5C5R C;  5ADQ B;  2ZIX B;  4L0B C;  4L0V C;  4L2F C;  4UI5 C;  4HKI C;  4HLF C;  4L34 C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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