4JCJA

Crystal structure of isl1 lim domains with ldb1 lim-interaction domain
Total Genus 22
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
22
sequence length
165
structure length
144
Chain Sequence
ISLCVGCGNQIHDQYILRVSPDLEWHAACLKCAECNQYLDESCTCFVRDGKTYCKRDYIRLYGIKCAKCSIGFSKNDFVMRARSKVYHIECFRCVACSRQLIPGDEFALREDGLFCRADHDDVMVVGEPTLMDEDERLITRLEN
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title A structural basis for the regulation of the LIM-homeodomain protein islet 1 (Isl1) by intra- and intermolecular interactions.
pubmed doi rcsb
molecule tags Protein binding
source organism Mus musculus
molecule keywords Insulin gene enhancer protein ISL-1,LIM domain-binding prote
total genus 22
structure length 144
sequence length 165
chains with identical sequence B, C
ec nomenclature
pdb deposition date 2013-02-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00412 LIM LIM domain
A PF17916 LID LIM interaction domain (LID)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.110.10 Mainly Beta Ribbon Cysteine Rich Protein Cysteine Rich Protein 4jcjA01
2.10.110.10 Mainly Beta Ribbon Cysteine Rich Protein Cysteine Rich Protein 4jcjA02
2EHEA 1CTLA 2CUQA 2O10A 1X62A 2DFYC 1M3VA 1X63A 2YPAC 2MIUA 3MMKA 3IXEB 1X4LA 1WYHA 1X64A 2CO8A 2IYBE 2D8YA 1WIGA 2KBXB 2L6ZC 1IMLA 1IBIA 2O13A 4KFZA 2DJ7A 2EGQA 2LXDA 2D8ZA 1J2OA 1B8TA 2CU8A 4HI8B 2XJYA 1A7IA 1X6AA 1X3HA 2XQNT 2DARA 2CORA 2CUPA 4HI9B 1RUTX 4JCJA 1G47A 1U5SB 1X61A 3F6QB 1QLIA 1NYPA 2JTNA 2D8XA 2XJZA 1CXXA 2CURA 1V6GA 1X68A 2MBVA 2DLOA 2L6YB 2L4ZA 2LZUA
chains in the Genus database with same CATH superfamily
2O10A 2DFYC 2YPAC 1X4LA 5A1LA 5FXVA 2CO8A 5FY7A 2D8YA 5FYMA 1IMLA 2O13A 2DJ7A 1J2OA 2CU8A 4HI8B 3NIMA 5LKUA 2XJZA 1X68A 4UF0B 1CTLA 2CUQA 3ZPOA 1WYHA 1WIGA 4EZHA 3NISA 2DARA 2CORA 1G47A 1U5SB 1NYPA 4EYUA 5FY1A 2D8XA 5FXZA 1V6GA 2MBVA 2L6YB 2LZUA 5LKTA 1X62A 1M3VA 1X63A 2MIUA 3MMKA 3IXEB 5FP3A 3NIHA 5FXXA 1X64A 5LKXA 1IBIA 3NILA 2LXDA 3NIJA 2D8ZA 3AVRA 1X6AA 4HI9B 1RUTX 3ZLIA 2JTNA 4BHWA 2CURA 2DLOA 2L4ZA 2EHEA 3NIKA 5LKZA 2IYBE 2KBXB 2L6ZC 4KFZA 2EGQA 5FXWA 1B8TA 2XJYA 1A7IA 3AVSA 1X3HA 2XQNT 4EZ4A 4JCJA 2CUPA 1X61A 2XUEA 3F6QB 1QLIA 3NINA 1CXXA 5FY0A 4ASKA 4UF0A
chains in the Genus database with same CATH topology
2O10A 2DFYC 2YPAC 1X4LA 5A1LA 5FXVA 2CO8A 5FY7A 2D8YA 5FYMA 1IMLA 2O13A 2DJ7A 1J2OA 2CU8A 4HI8B 3NIMA 5LKUA 2XJZA 1X68A 4UF0B 1CTLA 2CUQA 3ZPOA 1WYHA 1WIGA 4EZHA 3NISA 2DARA 2CORA 1G47A 1U5SB 1NYPA 4EYUA 5FY1A 2D8XA 5FXZA 1V6GA 2MBVA 2L6YB 2LZUA 5LKTA 1X62A 1M3VA 1X63A 2MIUA 3MMKA 3IXEB 5FP3A 3NIHA 5FXXA 1X64A 5LKXA 1IBIA 3NILA 2LXDA 3NIJA 2D8ZA 3AVRA 1X6AA 4HI9B 1RUTX 3ZLIA 2JTNA 4BHWA 2CURA 2DLOA 2L4ZA 2EHEA 3NIKA 5LKZA 2IYBE 2KBXB 2L6ZC 4KFZA 2EGQA 5FXWA 1B8TA 2XJYA 1A7IA 3AVSA 1X3HA 2XQNT 4EZ4A 4JCJA 2CUPA 1X61A 2XUEA 3F6QB 1QLIA 3NINA 1CXXA 5FY0A 4ASKA 4UF0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2EHE A;  1CTL A;  2CUQ A;  2O10 A;  1X62 A;  2DFY C;  1M3V A;  1X63 A;  2YPA C;  2MIU A;  3MMK A;  3IXE B;  1X4L A;  1WYH A;  1X64 A;  2CO8 A;  2IYB E;  2D8Y A;  1WIG A;  2KBX B;  2L6Z C;  1IML A;  1IBI A;  2O13 A;  4KFZ A;  2DJ7 A;  2EGQ A;  2LXD A;  2D8Z A;  1J2O A;  1B8T A;  2CU8 A;  4HI8 B;  2XJY A;  1A7I A;  1X6A A;  1X3H A;  2XQN T;  2DAR A;  2COR A;  2CUP A;  4HI9 B;  1RUT X;  4JCJ A;  1G47 A;  1U5S B;  1X61 A;  3F6Q B;  1QLI A;  1NYP A;  2JTN A;  2D8X A;  2XJZ A;  1CXX A;  2CUR A;  1V6G A;  1X68 A;  2MBV A;  2DLO A;  2L6Y B;  2L4Z A;  2LZU A; 
#chains in the Genus database with same CATH topology
 2O10 A;  2DFY C;  2YPA C;  1X4L A;  5A1L A;  5FXV A;  2CO8 A;  5FY7 A;  2D8Y A;  5FYM A;  1IML A;  2O13 A;  2DJ7 A;  1J2O A;  2CU8 A;  4HI8 B;  3NIM A;  5LKU A;  2XJZ A;  1X68 A;  4UF0 B;  1CTL A;  2CUQ A;  3ZPO A;  1WYH A;  1WIG A;  4EZH A;  3NIS A;  2DAR A;  2COR A;  1G47 A;  1U5S B;  1NYP A;  4EYU A;  5FY1 A;  2D8X A;  5FXZ A;  1V6G A;  2MBV A;  2L6Y B;  2LZU A;  5LKT A;  1X62 A;  1M3V A;  1X63 A;  2MIU A;  3MMK A;  3IXE B;  5FP3 A;  3NIH A;  5FXX A;  1X64 A;  5LKX A;  1IBI A;  3NIL A;  2LXD A;  3NIJ A;  2D8Z A;  3AVR A;  1X6A A;  4HI9 B;  1RUT X;  3ZLI A;  2JTN A;  4BHW A;  2CUR A;  2DLO A;  2L4Z A;  2EHE A;  3NIK A;  5LKZ A;  2IYB E;  2KBX B;  2L6Z C;  4KFZ A;  2EGQ A;  5FXW A;  1B8T A;  2XJY A;  1A7I A;  3AVS A;  1X3H A;  2XQN T;  4EZ4 A;  4JCJ A;  2CUP A;  1X61 A;  2XUE A;  3F6Q B;  1QLI A;  3NIN A;  1CXX A;  5FY0 A;  4ASK A;  4UF0 A; 
#chains in the Genus database with same CATH homology
 2O10 A;  2DFY C;  2YPA C;  1X4L A;  5A1L A;  5FXV A;  2CO8 A;  5FY7 A;  2D8Y A;  5FYM A;  1IML A;  2O13 A;  2DJ7 A;  1J2O A;  2CU8 A;  4HI8 B;  3NIM A;  5LKU A;  2XJZ A;  1X68 A;  4UF0 B;  1CTL A;  2CUQ A;  3ZPO A;  1WYH A;  1WIG A;  4EZH A;  3NIS A;  2DAR A;  2COR A;  1G47 A;  1U5S B;  1NYP A;  4EYU A;  5FY1 A;  2D8X A;  5FXZ A;  1V6G A;  2MBV A;  2L6Y B;  2LZU A;  5LKT A;  1X62 A;  1M3V A;  1X63 A;  2MIU A;  3MMK A;  3IXE B;  5FP3 A;  3NIH A;  5FXX A;  1X64 A;  5LKX A;  1IBI A;  3NIL A;  2LXD A;  3NIJ A;  2D8Z A;  3AVR A;  1X6A A;  4HI9 B;  1RUT X;  3ZLI A;  2JTN A;  4BHW A;  2CUR A;  2DLO A;  2L4Z A;  2EHE A;  3NIK A;  5LKZ A;  2IYB E;  2KBX B;  2L6Z C;  4KFZ A;  2EGQ A;  5FXW A;  1B8T A;  2XJY A;  1A7I A;  3AVS A;  1X3H A;  2XQN T;  4EZ4 A;  4JCJ A;  2CUP A;  1X61 A;  2XUE A;  3F6Q B;  1QLI A;  3NIN A;  1CXX A;  5FY0 A;  4ASK A;  4UF0 A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...