4LK0E

Crystal structure analysis of the e.coli holoenzyme/t7 gp2 complex
Total Genus 27
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
27
sequence length
89
structure length
89
Chain Sequence
ARVTVQDAVEKIGNRFDLVLVAARRARQMQVGGKDPLVPEENDKTTVIALREIEEGLINNQILDVRERQEQQEQEAAELQAVTAIAEGR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Phage T7 Gp2 inhibition of Escherichia coli RNA polymerase involves misappropriation of sigma 70 domain 1.1.
pubmed doi rcsb
molecule tags Transferase
source organism Escherichia coli
molecule keywords DNA-directed RNA polymerase subunit alpha
total genus 27
structure length 89
sequence length 89
chains with identical sequence K
ec nomenclature ec 2.7.7.6: DNA-directed RNA polymerase.
pdb deposition date 2013-07-05
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.940.10 Alpha Beta Alpha-Beta Complex Eukaryotic RPB6 RNA polymerase subunit Eukaryotic RPB6 RNA polymerase subunit 4lk0E00
3GTGF 5IYBF 4OIOE 1Y1VF 2WB1I 5D4DE 3S14F 2O5JE 3S1MF 3M4OF 4A3EF 2E2JF 5E17E 3M3YF 1TWHF 2NVYF 1YNNK 5BYHE 5IYCF 3GTMF 3H3VG 2B63F 3HOZF 3I4NF 1K83F 4A3IF 2R92F 1TWFF 4Q4ZE 4Y7NF 5M5WF 4LJZE 4XLPE 4Y52F 4G7ZE 1SMYE 4A3LF 5TMCE 1YNJK 2JA5F 2NVXF 4KN7E 4LK0E 3EQLE 4XLNE 3GTQF 2YU9F 3H0GF 4BY7F 4C3JF 4LLGE 1IW7E 3WODE 3S15F 2R93F 2WAQK 4JK1E 5M3FF 5D4CE 2JA8F 3S1NF 3GTOF 5IP7F 2CW0E 2JA7F 3S17F 1I6VE 4GZYE 5D4EE 5IPLE 1SFOF 4LK1E 3HOXF 4OINE 4YG2E 3RZOF 4C2MF 5C3EF 3PO3F 4X6AF 3S2DF 4A3DF 3HOVF 4XSXE 3S1QF 5C44F 1TWGF 5IP9F 4MEXE 3HOWF 3HKZK 4OIQE 2A68E 3GTPF 4YFXE 5M5XF 2Y0SI 3S2HF 4BXXF 2BE5E 3S1RF 2O5IE 4OIPE 3RZDF 1ZYRE 4A3CF 2PMZK 2E2HF 4C3HF 2JA6F 3CQZF 3GTKF 3I4MF 4C3IF 4BBSF 4XSZE 4A3JF 5IYDF 4YFKE 3PO2F 4ZH4E 3GTLF 4A3FF 2R7ZF 4KN4E 2VUMF 4A3MF 2NVQF 3HOYF 1I50F 1Y1WF 3FKIF 4YFNE 4BBRF 2A6EE 2A69E 5M3MF 1TWAF 2A6HE 5M5YF 4A3GF 2NVTF 3HOUF 1HQME 5FJ8F 5TMFE 4BY1F 4A93F 1R9TF 1I6HF 4G7OE 2PPBE 5C4XF 1TWCF 4AYBK 4A3BF 4G7HE 4KMUE 4MEYE 2E2IF 4MQ9E 3DXJE 4A3KF 3K7AF 3GTJF 1WCMF 5E18E 1I3QF 4OIRE 3S16F 5C4JF 4Q5SE 1QKLA 5FLMF
chains in the Genus database with same CATH superfamily
3GTGF 1EIKA 5IYBF 4OIOE 2VUME 1Y1VF 4QIWK 2WB1I 5D4DE 3S14F 2NVQE 3S1MF 3M4OF 3HOYE 1I50E 4A3EF 1Y1WE 2E2JF 2O5JE 5E17E 3M3YF 2WAQH 1TWHF 2NVYF 1YNNK 4BBRE 5BYHE 5M5XE 5IYCF 3GTPE 3GTMF 3H3VG 2B63F 4BXXE 3HOZF 5M3ME 3I4NF 3S1RE 1K83F 4A3IF 2R92F 5M5YE 1TWFF 4Q4ZE 3HOUE 4A3GE 4Y7NF 5FJ8E 5M5WF 2JA6E 4BY1E 4LJZE 4XLPE 4Y52F 4G7ZE 1SMYE 1R9TE 1I6HE 4A3LF 5TMCE 5IYDE 1YNJK 2JA5F 2NVXF 4KN7E 3HKZH 4LK0E 3EQLE 4A3FE 2E2IE 4XLNE 4A3KE 3K7AE 3GTJE 2R7ZE 1WCME 3GTQF 2YU9F 1I3QE 3H0GF 4BY7F 4C3JF 4LLGE 1IW7E 3WODE 5C4JE 4A3ME 3S16E 3S15F 2WAQK 4JK1E 5M3FF 5D4CE 2JA8F 5FLME 3S1NF 3GTOF 5IP7F 5IYBE 1Y1VE 2CW0E 2KRXA 3FKIE 2PMZH 2JA7F 3S14E 1I6VE 3S17F 5D4EE 3S1ME 3M4OE 4A3EE 4GZYE 2E2JE 5IPLE 1SFOF 3M3YE 4LK1E 3HOXF 2Y0SH 2NVYE 4OINE 4YG2E 3RZOF 4C2MF 1TWAE 5IYCE 5C3EF 3PO3F 3GTME 2R93F 4X6AF 3S2DF 2B63E 2NVTE 4A3DF 3HOVF 3HOZE 4XSXE 3I4NE 3S1QF 5C44F 4A3IE 2R92E 1TWGF 1TWFE 5IP9F 4MEXE 3GTLE 4A93E 3HOWF 5C4XE 1DZFA 3HKZK 1TWCE 5M5WE 4A3BE 4OIQE 4Y52E 2A68E 3GTPF 4YFXE 5M5XF 2Y0SI 3S2HF 4A3LE 2JA5E 4BXXF 2BE5E 3S1RF 2O5IE 4OIPE 3RZDF 1ZYRE 4A3CF 2PMZK 2E2HF 3GTGE 2YU9E 4C3HF 4C3JE 4BY7E 2R93E 2JA6F 3S1NE 3CQZF 3GTKF 2JA8E 3I4MF 3GTOE 5IP7E 4C3IF 3S17E 4BBSF 4XSZE 1TWHE 4A3JF 5IYDF 4YFKE 1SFOE 4ZH4E 3GTLF 4AYBH 4A3FF 3PO2F 3HOXE 2R7ZF 4KN4E 2VUMF 3RZOE 1K83E 4C2ME 4A3MF 2NVQF 3HOYF 1I50F 4X6AE 1Y1WF 4A3DE 3HOVE 4Y7NE 3FKIF 3S1QE 4YFNE 5C44E 1TWGE 4QIWH 5IP9E 4BBRF 2A6EE 3HOWE 2A69E 2NVXE 5M3MF 1TWAF 2A6HE 5M5YF 4A3GF 2NVTF 3GTQE 3H0GE 3HOUF 1HQME 3S2HE 2WB1H 5FJ8F 3S15E 5M3FE 5TMFE 4BY1F 3RZDE 4A3CE 2E2HE 4C3HE 2JA7E 4A93F 1R9TF 1I6HF 4G7OE 2PPBE 5C4XF 1TWCF 4AYBK 3CQZE 4G7HE 3GTKE 4A3BF 3I4ME 3H3VF 4KMUE 4MEYE 2E2IF 4MQ9E 4C3IE 3DXJE 4A3KF 3K7AF 3GTJF 4BBSE 1WCMF 5E18E 4A3JE 1I3QF 4OIRE 3S16F 5C4JF 4Q5SE 5C3EE 3PO2E 3PO3E 1QKLA 3S2DE 5FLMF
chains in the Genus database with same CATH topology
3GTGF 5IYBF 4OIOE 1Y1VF 4QIWK 2WB1I 5D4DE 3S14F 2O5JE 3S1MF 3M4OF 4A3EF 2E2JF 5E17E 3M3YF 1TWHF 2NVYF 1YNNK 5BYHE 5IYCF 3GTMF 3H3VG 2B63F 3HOZF 3I4NF 1K83F 4A3IF 2R92F 1TWFF 4Q4ZE 4Y7NF 5M5WF 4LJZE 4XLPE 4Y52F 4G7ZE 1SMYE 4A3LF 5TMCE 1YNJK 2JA5F 2NVXF 4KN7E 4LK0E 3EQLE 4XLNE 3GTQF 2YU9F 3H0GF 4BY7F 4C3JF 4LLGE 1IW7E 3WODE 3S15F 2R93F 2WAQK 4JK1E 5M3FF 5D4CE 2JA8F 3S1NF 3GTOF 5IP7F 2CW0E 2KRXA 2JA7F 3S17F 1I6VE 4GZYE 5D4EE 5IPLE 1SFOF 4LK1E 3HOXF 4OINE 4YG2E 3RZOF 4C2MF 5C3EF 3PO3F 4X6AF 3S2DF 4A3DF 3HOVF 4XSXE 3S1QF 5C44F 1TWGF 5IP9F 4MEXE 3HOWF 3HKZK 4OIQE 2A68E 3GTPF 4YFXE 5M5XF 2Y0SI 3S2HF 4BXXF 2BE5E 3S1RF 2O5IE 4OIPE 3RZDF 1ZYRE 4A3CF 2PMZK 2E2HF 4C3HF 2JA6F 3CQZF 3GTKF 3I4MF 4C3IF 4BBSF 4XSZE 4A3JF 5IYDF 4YFKE 3PO2F 4ZH4E 3GTLF 4A3FF 2R7ZF 4KN4E 2VUMF 4A3MF 2NVQF 3HOYF 1I50F 1Y1WF 3FKIF 4YFNE 4BBRF 2A6EE 2A69E 5M3MF 1TWAF 2A6HE 5M5YF 4A3GF 2NVTF 3HOUF 1HQME 5FJ8F 5TMFE 4BY1F 4A93F 1R9TF 1I6HF 4G7OE 2PPBE 5C4XF 1TWCF 4AYBK 4A3BF 4G7HE 4KMUE 4MEYE 2E2IF 4MQ9E 3DXJE 4A3KF 3K7AF 3GTJF 1WCMF 5E18E 1I3QF 4OIRE 3S16F 5C4JF 4Q5SE 1QKLA 5FLMF
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3GTG F;  5IYB F;  4OIO E;  1Y1V F;  2WB1 I;  5D4D E;  3S14 F;  2O5J E;  3S1M F;  3M4O F;  4A3E F;  2E2J F;  5E17 E;  3M3Y F;  1TWH F;  2NVY F;  1YNN K;  5BYH E;  5IYC F;  3GTM F;  3H3V G;  2B63 F;  3HOZ F;  3I4N F;  1K83 F;  4A3I F;  2R92 F;  1TWF F;  4Q4Z E;  4Y7N F;  5M5W F;  4LJZ E;  4XLP E;  4Y52 F;  4G7Z E;  1SMY E;  4A3L F;  5TMC E;  1YNJ K;  2JA5 F;  2NVX F;  4KN7 E;  4LK0 E;  3EQL E;  4XLN E;  3GTQ F;  2YU9 F;  3H0G F;  4BY7 F;  4C3J F;  4LLG E;  1IW7 E;  3WOD E;  3S15 F;  2R93 F;  2WAQ K;  4JK1 E;  5M3F F;  5D4C E;  2JA8 F;  3S1N F;  3GTO F;  5IP7 F;  2CW0 E;  2JA7 F;  3S17 F;  1I6V E;  4GZY E;  5D4E E;  5IPL E;  1SFO F;  4LK1 E;  3HOX F;  4OIN E;  4YG2 E;  3RZO F;  4C2M F;  5C3E F;  3PO3 F;  4X6A F;  3S2D F;  4A3D F;  3HOV F;  4XSX E;  3S1Q F;  5C44 F;  1TWG F;  5IP9 F;  4MEX E;  3HOW F;  3HKZ K;  4OIQ E;  2A68 E;  3GTP F;  4YFX E;  5M5X F;  2Y0S I;  3S2H F;  4BXX F;  2BE5 E;  3S1R F;  2O5I E;  4OIP E;  3RZD F;  1ZYR E;  4A3C F;  2PMZ K;  2E2H F;  4C3H F;  2JA6 F;  3CQZ F;  3GTK F;  3I4M F;  4C3I F;  4BBS F;  4XSZ E;  4A3J F;  5IYD F;  4YFK E;  3PO2 F;  4ZH4 E;  3GTL F;  4A3F F;  2R7Z F;  4KN4 E;  2VUM F;  4A3M F;  2NVQ F;  3HOY F;  1I50 F;  1Y1W F;  3FKI F;  4YFN E;  4BBR F;  2A6E E;  2A69 E;  5M3M F;  1TWA F;  2A6H E;  5M5Y F;  4A3G F;  2NVT F;  3HOU F;  1HQM E;  5FJ8 F;  5TMF E;  4BY1 F;  4A93 F;  1R9T F;  1I6H F;  4G7O E;  2PPB E;  5C4X F;  1TWC F;  4AYB K;  4A3B F;  4G7H E;  4KMU E;  4MEY E;  2E2I F;  4MQ9 E;  3DXJ E;  4A3K F;  3K7A F;  3GTJ F;  1WCM F;  5E18 E;  1I3Q F;  4OIR E;  3S16 F;  5C4J F;  4Q5S E;  1QKL A;  5FLM F; 
#chains in the Genus database with same CATH topology
 3GTG F;  1EIK A;  5IYB F;  4OIO E;  2VUM E;  1Y1V F;  4QIW K;  2WB1 I;  5D4D E;  3S14 F;  2NVQ E;  3S1M F;  3M4O F;  3HOY E;  1I50 E;  4A3E F;  1Y1W E;  2E2J F;  2O5J E;  5E17 E;  3M3Y F;  2WAQ H;  1TWH F;  2NVY F;  1YNN K;  4BBR E;  5BYH E;  5M5X E;  5IYC F;  3GTP E;  3GTM F;  3H3V G;  2B63 F;  4BXX E;  3HOZ F;  5M3M E;  3I4N F;  3S1R E;  1K83 F;  4A3I F;  2R92 F;  5M5Y E;  1TWF F;  4Q4Z E;  3HOU E;  4A3G E;  4Y7N F;  5FJ8 E;  5M5W F;  2JA6 E;  4BY1 E;  4LJZ E;  4XLP E;  4Y52 F;  4G7Z E;  1SMY E;  1R9T E;  1I6H E;  4A3L F;  5TMC E;  5IYD E;  1YNJ K;  2JA5 F;  2NVX F;  4KN7 E;  3HKZ H;  4LK0 E;  3EQL E;  4A3F E;  2E2I E;  4XLN E;  4A3K E;  3K7A E;  3GTJ E;  2R7Z E;  1WCM E;  3GTQ F;  2YU9 F;  1I3Q E;  3H0G F;  4BY7 F;  4C3J F;  4LLG E;  1IW7 E;  3WOD E;  5C4J E;  4A3M E;  3S16 E;  3S15 F;  2WAQ K;  4JK1 E;  5M3F F;  5D4C E;  2JA8 F;  5FLM E;  3S1N F;  3GTO F;  5IP7 F;  5IYB E;  1Y1V E;  2CW0 E;  2KRX A;  3FKI E;  2PMZ H;  2JA7 F;  3S14 E;  1I6V E;  3S17 F;  5D4E E;  3S1M E;  3M4O E;  4A3E E;  4GZY E;  2E2J E;  5IPL E;  1SFO F;  3M3Y E;  4LK1 E;  3HOX F;  2Y0S H;  2NVY E;  4OIN E;  4YG2 E;  3RZO F;  4C2M F;  1TWA E;  5IYC E;  5C3E F;  3PO3 F;  3GTM E;  2R93 F;  4X6A F;  3S2D F;  2B63 E;  2NVT E;  4A3D F;  3HOV F;  3HOZ E;  4XSX E;  3I4N E;  3S1Q F;  5C44 F;  4A3I E;  2R92 E;  1TWG F;  1TWF E;  5IP9 F;  4MEX E;  3GTL E;  4A93 E;  3HOW F;  5C4X E;  1DZF A;  3HKZ K;  1TWC E;  5M5W E;  4A3B E;  4OIQ E;  4Y52 E;  2A68 E;  3GTP F;  4YFX E;  5M5X F;  2Y0S I;  3S2H F;  4A3L E;  2JA5 E;  4BXX F;  2BE5 E;  3S1R F;  2O5I E;  4OIP E;  3RZD F;  1ZYR E;  4A3C F;  2PMZ K;  2E2H F;  3GTG E;  2YU9 E;  4C3H F;  4C3J E;  4BY7 E;  2R93 E;  2JA6 F;  3S1N E;  3CQZ F;  3GTK F;  2JA8 E;  3I4M F;  3GTO E;  5IP7 E;  4C3I F;  3S17 E;  4BBS F;  4XSZ E;  1TWH E;  4A3J F;  5IYD F;  4YFK E;  1SFO E;  4ZH4 E;  3GTL F;  4AYB H;  4A3F F;  3PO2 F;  3HOX E;  2R7Z F;  4KN4 E;  2VUM F;  3RZO E;  1K83 E;  4C2M E;  4A3M F;  2NVQ F;  3HOY F;  1I50 F;  4X6A E;  1Y1W F;  4A3D E;  3HOV E;  4Y7N E;  3FKI F;  3S1Q E;  4YFN E;  5C44 E;  1TWG E;  4QIW H;  5IP9 E;  4BBR F;  2A6E E;  3HOW E;  2A69 E;  2NVX E;  5M3M F;  1TWA F;  2A6H E;  5M5Y F;  4A3G F;  2NVT F;  3GTQ E;  3H0G E;  3HOU F;  1HQM E;  3S2H E;  2WB1 H;  5FJ8 F;  3S15 E;  5M3F E;  5TMF E;  4BY1 F;  3RZD E;  4A3C E;  2E2H E;  4C3H E;  2JA7 E;  4A93 F;  1R9T F;  1I6H F;  4G7O E;  2PPB E;  5C4X F;  1TWC F;  4AYB K;  3CQZ E;  4G7H E;  3GTK E;  4A3B F;  3I4M E;  3H3V F;  4KMU E;  4MEY E;  2E2I F;  4MQ9 E;  4C3I E;  3DXJ E;  4A3K F;  3K7A F;  3GTJ F;  4BBS E;  1WCM F;  5E18 E;  4A3J E;  1I3Q F;  4OIR E;  3S16 F;  5C4J F;  4Q5S E;  5C3E E;  3PO2 E;  3PO3 E;  1QKL A;  3S2D E;  5FLM F; 
#chains in the Genus database with same CATH homology
 3GTG F;  5IYB F;  4OIO E;  1Y1V F;  4QIW K;  2WB1 I;  5D4D E;  3S14 F;  2O5J E;  3S1M F;  3M4O F;  4A3E F;  2E2J F;  5E17 E;  3M3Y F;  1TWH F;  2NVY F;  1YNN K;  5BYH E;  5IYC F;  3GTM F;  3H3V G;  2B63 F;  3HOZ F;  3I4N F;  1K83 F;  4A3I F;  2R92 F;  1TWF F;  4Q4Z E;  4Y7N F;  5M5W F;  4LJZ E;  4XLP E;  4Y52 F;  4G7Z E;  1SMY E;  4A3L F;  5TMC E;  1YNJ K;  2JA5 F;  2NVX F;  4KN7 E;  4LK0 E;  3EQL E;  4XLN E;  3GTQ F;  2YU9 F;  3H0G F;  4BY7 F;  4C3J F;  4LLG E;  1IW7 E;  3WOD E;  3S15 F;  2R93 F;  2WAQ K;  4JK1 E;  5M3F F;  5D4C E;  2JA8 F;  3S1N F;  3GTO F;  5IP7 F;  2CW0 E;  2KRX A;  2JA7 F;  3S17 F;  1I6V E;  4GZY E;  5D4E E;  5IPL E;  1SFO F;  4LK1 E;  3HOX F;  4OIN E;  4YG2 E;  3RZO F;  4C2M F;  5C3E F;  3PO3 F;  4X6A F;  3S2D F;  4A3D F;  3HOV F;  4XSX E;  3S1Q F;  5C44 F;  1TWG F;  5IP9 F;  4MEX E;  3HOW F;  3HKZ K;  4OIQ E;  2A68 E;  3GTP F;  4YFX E;  5M5X F;  2Y0S I;  3S2H F;  4BXX F;  2BE5 E;  3S1R F;  2O5I E;  4OIP E;  3RZD F;  1ZYR E;  4A3C F;  2PMZ K;  2E2H F;  4C3H F;  2JA6 F;  3CQZ F;  3GTK F;  3I4M F;  4C3I F;  4BBS F;  4XSZ E;  4A3J F;  5IYD F;  4YFK E;  3PO2 F;  4ZH4 E;  3GTL F;  4A3F F;  2R7Z F;  4KN4 E;  2VUM F;  4A3M F;  2NVQ F;  3HOY F;  1I50 F;  1Y1W F;  3FKI F;  4YFN E;  4BBR F;  2A6E E;  2A69 E;  5M3M F;  1TWA F;  2A6H E;  5M5Y F;  4A3G F;  2NVT F;  3HOU F;  1HQM E;  5FJ8 F;  5TMF E;  4BY1 F;  4A93 F;  1R9T F;  1I6H F;  4G7O E;  2PPB E;  5C4X F;  1TWC F;  4AYB K;  4A3B F;  4G7H E;  4KMU E;  4MEY E;  2E2I F;  4MQ9 E;  3DXJ E;  4A3K F;  3K7A F;  3GTJ F;  1WCM F;  5E18 E;  1I3Q F;  4OIR E;  3S16 F;  5C4J F;  4Q5S E;  1QKL A;  5FLM F; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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