4LLGE

Crystal structure analysis of the e.coli holoenzyme/gp2 complex
Total Genus 25
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
25
sequence length
89
structure length
89
Chain Sequence
ARVTVQDAVEKIGNRFDLVLVAARRARQMQVGGKDPLVPEENDKTTVIALREIEEGLINNQILDVRERQEQQEQEAAELQAVTAIAEGR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Phage T7 Gp2 inhibition of Escherichia coli RNA polymerase involves misappropriation of sigma 70 domain 1.1.
pubmed doi rcsb
molecule tags Transferase
source organism Escherichia coli
molecule keywords DNA-directed RNA polymerase subunit alpha
total genus 25
structure length 89
sequence length 89
chains with identical sequence K
ec nomenclature ec 2.7.7.6: DNA-directed RNA polymerase.
pdb deposition date 2013-07-09
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.940.10 Alpha Beta Alpha-Beta Complex Eukaryotic RPB6 RNA polymerase subunit Eukaryotic RPB6 RNA polymerase subunit 4llgE00
4A3GF 3HOZF 4OIPE 3HOYF 2CW0E 5M3FF 4OIOE 1SMYE 4OINE 1I6VE 2O5IE 3GTOF 3GTQF 1YNNK 4MQ9E 4LK0E 4A3IF 4ZH4E 4A3EF 4Y7NF 5IYDF 1Y1WF 1TWHF 5M5WF 5M3MF 5FJ8F 4XLNE 1R9TF 3GTMF 3S1QF 3HOXF 4YFXE 4KMUE 2R7ZF 3S15F 5D4DE 3S1NF 1K83F 1TWAF 5IPLE 2R93F 2E2HF 1HQME 5C44F 2NVQF 4BBSF 5FLMF 2E2IF 2JA7F 1ZYRE 3H3VG 5IP9F 3HOWF 4G7ZE 1I50F 4C3JF 4C3HF 2E2JF 4YG2E 3I4MF 3GTPF 5M5YF 4XLPE 1IW7E 4OIQE 3PO3F 5E18E 5M5XF 3I4NF 5BYHE 4XSXE 4LK1E 1TWGF 4AYBK 5C3EF 4A3BF 4A93F 3S2HF 4C2MF 1I3QF 5E17E 4A3KF 2NVXF 4G7OE 2O5JE 5IP7F 2Y0SI 1SFOF 2WAQK 1QKLA 3HKZK 4MEYE 3H0GF 4OIRE 4YFNE 2A69E 2BE5E 4BY1F 4JK1E 2NVYF 5IYCF 2A6EE 5TMCE 4KN7E 3FKIF 3WODE 3CQZF 4XSZE 3RZOF 5C4XF 4X6AF 3DXJE 4BY7F 1TWFF 4Q5SE 1Y1VF 4LJZE 4BXXF 4GZYE 2A68E 3S14F 4C3IF 4A3LF 3GTKF 3S2DF 3GTJF 2JA8F 3S17F 4YFKE 4A3FF 3GTGF 2B63F 3M4OF 2JA5F 3S16F 4BBRF 2NVTF 4G7HE 3HOVF 2PPBE 2VUMF 1YNJK 3HOUF 2PMZK 5D4EE 4Y52F 4A3DF 3PO2F 1WCMF 3S1MF 4LLGE 3S1RF 5C4JF 3RZDF 4KN4E 4A3CF 3EQLE 2R92F 5IYBF 2YU9F 4Q4ZE 5D4CE 4MEXE 3GTLF 4A3MF 1TWCF 3M3YF 2A6HE 3K7AF 2JA6F 2WB1I 4A3JF 5TMFE 1I6HF
chains in the Genus database with same CATH superfamily
3FKIE 4A3GF 3CQZE 3HOZF 4OIPE 3HOYF 3RZOE 2CW0E 4X6AE 5M3FF 4OIOE 4BY7E 1TWFE 3S2HE 4BXXE 1SMYE 4OINE 3S14E 4C3IE 4A3LE 3GTKE 1I6VE 2O5IE 3GTOF 3GTQF 1YNNK 4MQ9E 4LK0E 3GTJE 4A3IF 4ZH4E 3S17E 4A3EF 4A3FE 3GTGE 4Y7NF 5IYDF 1Y1WF 1TWHF 5M5WF 5M3MF 4BBRE 5FJ8F 1SFOE 2JA5E 2B63E 2NVTE 3HOVE 3S16E 4XLNE 1R9TF 2VUME 3GTMF 3HOUE 3S1QF 3HOXF 4Y52E 4YFXE 4KMUE 2R7ZF 3S15F 5D4DE 3PO2E 3M4OE 1K83F 2NVYE 1WCME 1TWAF 3S1ME 2E2HF 3S1NF 3S1RE 1HQME 5C4JE 5C44F 2NVQF 4BBSF 2R93F 5FLMF 3RZDE 2E2IF 1DZFA 2JA7F 4A3CE 1ZYRE 3H3VG 5IP9F 3HOWF 4G7ZE 2R92E 5IYBE 2YU9E 4GZYE 1I50F 5C4XE 4C3JF 4C3HF 2E2JF 3GTLE 4A3ME 4YG2E 1Y1VE 2Y0SH 3GTPF 5M5YF 4XLPE 3I4MF 3K7AE 1IW7E 4OIQE 3PO3F 5E18E 2JA8E 5M5XF 3I4NF 5BYHE 4A3GE 4XSXE 4LK1E 1TWGF 4AYBK 5C3EF 4A3BF 4A93F 3HOYE 3S2HF 3HOZE 4C2MF 1I3QF 4QIWK 5E17E 4A3KF 2NVXF 4G7OE 4A3DE 2O5JE 5IP7F 2Y0SI 3H3VF 1SFOF 3GTOE 2WAQK 1QKLA 3HKZK 4MEYE 3GTQE 4A3IE 3H0GF 4OIRE 4A3EE 4YFNE 5IYDE 4Y7NE 1Y1WE 1TWHE 2A69E 5M3ME 5M5WE 5FJ8E 2BE5E 4BY1F 1R9TE 4JK1E 3GTME 2NVYF 4AYBH 5IYCF 3S1QE 1TWCE 2A6EE 5TMCE 3HOXE 4QIWH 4KN7E 3FKIF 3S15E 3WODE 3M3YE 3S1NE 1K83E 1TWAE 3CQZF 2E2HE 4A3JE 4XSZE 2JA6E 1EIKA 5C44E 2NVQE 4BBSE 5FLME 3RZOF 2E2IE 1I6HE 5C4XF 4X6AF 2JA7E 2WAQH 3DXJE 3HKZH 4BY7F 5IP9E 1TWFF 4Q5SE 1Y1VF 1I50E 4LJZE 4BXXF 4C3JE 4C3HE 2E2JE 2A68E 3S14F 4C3IF 4A3LF 5M3FE 3GTKF 3S2DF 3GTJF 2JA8F 3S17F 4YFKE 3I4ME 3GTPE 5M5YE 4A3FF 3GTGF 2B63F 2KRXA 3M4OF 2JA5F 3S16F 4BBRF 2NVTF 3S2DE 4G7HE 3HOVF 2PPBE 3PO3E 2VUMF 1YNJK 5M5XE 3HOUF 3I4NE 2PMZK 5D4EE 1TWGE 4Y52F 5C3EE 4A3BE 4A93E 4A3DF 4C2ME 3PO2F 1I3QE 1WCMF 3S1MF 4LLGE 2WB1H 4A3KE 5C4JF 3S1RF 2NVXE 5IPLE 3RZDF 5IP7E 2R7ZE 4KN4E 4A3CF 3EQLE 2R92F 2R93E 5IYBF 2YU9F 4Q4ZE 5D4CE 3H0GE 4MEXE 3GTLF 4A3MF 1TWCF 3HOWE 3M3YF 2PMZH 4BY1E 2A6HE 3K7AF 5IYCE 2WB1I 4A3JF 2JA6F 5TMFE 1I6HF
chains in the Genus database with same CATH topology
4A3GF 3HOZF 4OIPE 3HOYF 2CW0E 5M3FF 4OIOE 1SMYE 4OINE 1I6VE 2O5IE 3GTOF 3GTQF 1YNNK 4MQ9E 4LK0E 4A3IF 4ZH4E 4A3EF 4Y7NF 5IYDF 1Y1WF 1TWHF 5M5WF 5M3MF 5FJ8F 4XLNE 1R9TF 3GTMF 3S1QF 3HOXF 4YFXE 4KMUE 2R7ZF 3S15F 5D4DE 3S1NF 1K83F 1TWAF 5IPLE 2R93F 2E2HF 1HQME 5C44F 2NVQF 4BBSF 5FLMF 2E2IF 2JA7F 1ZYRE 3H3VG 5IP9F 3HOWF 4G7ZE 1I50F 4C3JF 4C3HF 2E2JF 4YG2E 3I4MF 3GTPF 5M5YF 4XLPE 1IW7E 4OIQE 3PO3F 5E18E 5M5XF 3I4NF 5BYHE 4XSXE 4LK1E 1TWGF 4AYBK 5C3EF 4A3BF 4A93F 3S2HF 4C2MF 1I3QF 4QIWK 5E17E 4A3KF 2NVXF 4G7OE 2O5JE 5IP7F 2Y0SI 1SFOF 2WAQK 1QKLA 3HKZK 4MEYE 3H0GF 4OIRE 4YFNE 2A69E 2BE5E 4BY1F 4JK1E 2NVYF 5IYCF 2A6EE 5TMCE 4KN7E 3FKIF 3WODE 3CQZF 4XSZE 3RZOF 5C4XF 4X6AF 3DXJE 4BY7F 1TWFF 4Q5SE 1Y1VF 4LJZE 4BXXF 4GZYE 2A68E 3S14F 4C3IF 4A3LF 3GTKF 3S2DF 3GTJF 2JA8F 3S17F 4YFKE 4A3FF 3GTGF 2B63F 2KRXA 3M4OF 2JA5F 3S16F 4BBRF 2NVTF 4G7HE 3HOVF 2PPBE 2VUMF 1YNJK 3HOUF 2PMZK 5D4EE 4Y52F 4A3DF 3PO2F 1WCMF 3S1MF 4LLGE 3S1RF 5C4JF 3RZDF 4KN4E 4A3CF 3EQLE 2R92F 5IYBF 2YU9F 4Q4ZE 5D4CE 4MEXE 3GTLF 4A3MF 1TWCF 3M3YF 2A6HE 3K7AF 2JA6F 2WB1I 4A3JF 5TMFE 1I6HF
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4A3G F;  3HOZ F;  4OIP E;  3HOY F;  2CW0 E;  5M3F F;  4OIO E;  1SMY E;  4OIN E;  1I6V E;  2O5I E;  3GTO F;  3GTQ F;  1YNN K;  4MQ9 E;  4LK0 E;  4A3I F;  4ZH4 E;  4A3E F;  4Y7N F;  5IYD F;  1Y1W F;  1TWH F;  5M5W F;  5M3M F;  5FJ8 F;  4XLN E;  1R9T F;  3GTM F;  3S1Q F;  3HOX F;  4YFX E;  4KMU E;  2R7Z F;  3S15 F;  5D4D E;  3S1N F;  1K83 F;  1TWA F;  5IPL E;  2R93 F;  2E2H F;  1HQM E;  5C44 F;  2NVQ F;  4BBS F;  5FLM F;  2E2I F;  2JA7 F;  1ZYR E;  3H3V G;  5IP9 F;  3HOW F;  4G7Z E;  1I50 F;  4C3J F;  4C3H F;  2E2J F;  4YG2 E;  3I4M F;  3GTP F;  5M5Y F;  4XLP E;  1IW7 E;  4OIQ E;  3PO3 F;  5E18 E;  5M5X F;  3I4N F;  5BYH E;  4XSX E;  4LK1 E;  1TWG F;  4AYB K;  5C3E F;  4A3B F;  4A93 F;  3S2H F;  4C2M F;  1I3Q F;  5E17 E;  4A3K F;  2NVX F;  4G7O E;  2O5J E;  5IP7 F;  2Y0S I;  1SFO F;  2WAQ K;  1QKL A;  3HKZ K;  4MEY E;  3H0G F;  4OIR E;  4YFN E;  2A69 E;  2BE5 E;  4BY1 F;  4JK1 E;  2NVY F;  5IYC F;  2A6E E;  5TMC E;  4KN7 E;  3FKI F;  3WOD E;  3CQZ F;  4XSZ E;  3RZO F;  5C4X F;  4X6A F;  3DXJ E;  4BY7 F;  1TWF F;  4Q5S E;  1Y1V F;  4LJZ E;  4BXX F;  4GZY E;  2A68 E;  3S14 F;  4C3I F;  4A3L F;  3GTK F;  3S2D F;  3GTJ F;  2JA8 F;  3S17 F;  4YFK E;  4A3F F;  3GTG F;  2B63 F;  3M4O F;  2JA5 F;  3S16 F;  4BBR F;  2NVT F;  4G7H E;  3HOV F;  2PPB E;  2VUM F;  1YNJ K;  3HOU F;  2PMZ K;  5D4E E;  4Y52 F;  4A3D F;  3PO2 F;  1WCM F;  3S1M F;  4LLG E;  3S1R F;  5C4J F;  3RZD F;  4KN4 E;  4A3C F;  3EQL E;  2R92 F;  5IYB F;  2YU9 F;  4Q4Z E;  5D4C E;  4MEX E;  3GTL F;  4A3M F;  1TWC F;  3M3Y F;  2A6H E;  3K7A F;  2JA6 F;  2WB1 I;  4A3J F;  5TMF E;  1I6H F; 
#chains in the Genus database with same CATH topology
 3FKI E;  4A3G F;  3CQZ E;  3HOZ F;  4OIP E;  3HOY F;  3RZO E;  2CW0 E;  4X6A E;  5M3F F;  4OIO E;  4BY7 E;  1TWF E;  3S2H E;  4BXX E;  1SMY E;  4OIN E;  3S14 E;  4C3I E;  4A3L E;  3GTK E;  1I6V E;  2O5I E;  3GTO F;  3GTQ F;  1YNN K;  4MQ9 E;  4LK0 E;  3GTJ E;  4A3I F;  4ZH4 E;  3S17 E;  4A3E F;  4A3F E;  3GTG E;  4Y7N F;  5IYD F;  1Y1W F;  1TWH F;  5M5W F;  5M3M F;  4BBR E;  5FJ8 F;  1SFO E;  2JA5 E;  2B63 E;  2NVT E;  3HOV E;  3S16 E;  4XLN E;  1R9T F;  2VUM E;  3GTM F;  3HOU E;  3S1Q F;  3HOX F;  4Y52 E;  4YFX E;  4KMU E;  2R7Z F;  3S15 F;  5D4D E;  3PO2 E;  3M4O E;  1K83 F;  2NVY E;  1WCM E;  1TWA F;  3S1M E;  2E2H F;  3S1N F;  3S1R E;  1HQM E;  5C4J E;  5C44 F;  2NVQ F;  4BBS F;  2R93 F;  5FLM F;  3RZD E;  2E2I F;  1DZF A;  2JA7 F;  4A3C E;  1ZYR E;  3H3V G;  5IP9 F;  3HOW F;  4G7Z E;  2R92 E;  5IYB E;  2YU9 E;  4GZY E;  1I50 F;  5C4X E;  4C3J F;  4C3H F;  2E2J F;  3GTL E;  4A3M E;  4YG2 E;  1Y1V E;  2Y0S H;  3GTP F;  5M5Y F;  4XLP E;  3I4M F;  3K7A E;  1IW7 E;  4OIQ E;  3PO3 F;  5E18 E;  2JA8 E;  5M5X F;  3I4N F;  5BYH E;  4A3G E;  4XSX E;  4LK1 E;  1TWG F;  4AYB K;  5C3E F;  4A3B F;  4A93 F;  3HOY E;  3S2H F;  3HOZ E;  4C2M F;  1I3Q F;  4QIW K;  5E17 E;  4A3K F;  2NVX F;  4G7O E;  4A3D E;  2O5J E;  5IP7 F;  2Y0S I;  3H3V F;  1SFO F;  3GTO E;  2WAQ K;  1QKL A;  3HKZ K;  4MEY E;  3GTQ E;  4A3I E;  3H0G F;  4OIR E;  4A3E E;  4YFN E;  5IYD E;  4Y7N E;  1Y1W E;  1TWH E;  2A69 E;  5M3M E;  5M5W E;  5FJ8 E;  2BE5 E;  4BY1 F;  1R9T E;  4JK1 E;  3GTM E;  2NVY F;  4AYB H;  5IYC F;  3S1Q E;  1TWC E;  2A6E E;  5TMC E;  3HOX E;  4QIW H;  4KN7 E;  3FKI F;  3S15 E;  3WOD E;  3M3Y E;  3S1N E;  1K83 E;  1TWA E;  3CQZ F;  2E2H E;  4A3J E;  4XSZ E;  2JA6 E;  1EIK A;  5C44 E;  2NVQ E;  4BBS E;  5FLM E;  3RZO F;  2E2I E;  1I6H E;  5C4X F;  4X6A F;  2JA7 E;  2WAQ H;  3DXJ E;  3HKZ H;  4BY7 F;  5IP9 E;  1TWF F;  4Q5S E;  1Y1V F;  1I50 E;  4LJZ E;  4BXX F;  4C3J E;  4C3H E;  2E2J E;  2A68 E;  3S14 F;  4C3I F;  4A3L F;  5M3F E;  3GTK F;  3S2D F;  3GTJ F;  2JA8 F;  3S17 F;  4YFK E;  3I4M E;  3GTP E;  5M5Y E;  4A3F F;  3GTG F;  2B63 F;  2KRX A;  3M4O F;  2JA5 F;  3S16 F;  4BBR F;  2NVT F;  3S2D E;  4G7H E;  3HOV F;  2PPB E;  3PO3 E;  2VUM F;  1YNJ K;  5M5X E;  3HOU F;  3I4N E;  2PMZ K;  5D4E E;  1TWG E;  4Y52 F;  5C3E E;  4A3B E;  4A93 E;  4A3D F;  4C2M E;  3PO2 F;  1I3Q E;  1WCM F;  3S1M F;  4LLG E;  2WB1 H;  4A3K E;  5C4J F;  3S1R F;  2NVX E;  5IPL E;  3RZD F;  5IP7 E;  2R7Z E;  4KN4 E;  4A3C F;  3EQL E;  2R92 F;  2R93 E;  5IYB F;  2YU9 F;  4Q4Z E;  5D4C E;  3H0G E;  4MEX E;  3GTL F;  4A3M F;  1TWC F;  3HOW E;  3M3Y F;  2PMZ H;  4BY1 E;  2A6H E;  3K7A F;  5IYC E;  2WB1 I;  4A3J F;  2JA6 F;  5TMF E;  1I6H F; 
#chains in the Genus database with same CATH homology
 4A3G F;  3HOZ F;  4OIP E;  3HOY F;  2CW0 E;  5M3F F;  4OIO E;  1SMY E;  4OIN E;  1I6V E;  2O5I E;  3GTO F;  3GTQ F;  1YNN K;  4MQ9 E;  4LK0 E;  4A3I F;  4ZH4 E;  4A3E F;  4Y7N F;  5IYD F;  1Y1W F;  1TWH F;  5M5W F;  5M3M F;  5FJ8 F;  4XLN E;  1R9T F;  3GTM F;  3S1Q F;  3HOX F;  4YFX E;  4KMU E;  2R7Z F;  3S15 F;  5D4D E;  3S1N F;  1K83 F;  1TWA F;  5IPL E;  2R93 F;  2E2H F;  1HQM E;  5C44 F;  2NVQ F;  4BBS F;  5FLM F;  2E2I F;  2JA7 F;  1ZYR E;  3H3V G;  5IP9 F;  3HOW F;  4G7Z E;  1I50 F;  4C3J F;  4C3H F;  2E2J F;  4YG2 E;  3I4M F;  3GTP F;  5M5Y F;  4XLP E;  1IW7 E;  4OIQ E;  3PO3 F;  5E18 E;  5M5X F;  3I4N F;  5BYH E;  4XSX E;  4LK1 E;  1TWG F;  4AYB K;  5C3E F;  4A3B F;  4A93 F;  3S2H F;  4C2M F;  1I3Q F;  4QIW K;  5E17 E;  4A3K F;  2NVX F;  4G7O E;  2O5J E;  5IP7 F;  2Y0S I;  1SFO F;  2WAQ K;  1QKL A;  3HKZ K;  4MEY E;  3H0G F;  4OIR E;  4YFN E;  2A69 E;  2BE5 E;  4BY1 F;  4JK1 E;  2NVY F;  5IYC F;  2A6E E;  5TMC E;  4KN7 E;  3FKI F;  3WOD E;  3CQZ F;  4XSZ E;  3RZO F;  5C4X F;  4X6A F;  3DXJ E;  4BY7 F;  1TWF F;  4Q5S E;  1Y1V F;  4LJZ E;  4BXX F;  4GZY E;  2A68 E;  3S14 F;  4C3I F;  4A3L F;  3GTK F;  3S2D F;  3GTJ F;  2JA8 F;  3S17 F;  4YFK E;  4A3F F;  3GTG F;  2B63 F;  2KRX A;  3M4O F;  2JA5 F;  3S16 F;  4BBR F;  2NVT F;  4G7H E;  3HOV F;  2PPB E;  2VUM F;  1YNJ K;  3HOU F;  2PMZ K;  5D4E E;  4Y52 F;  4A3D F;  3PO2 F;  1WCM F;  3S1M F;  4LLG E;  3S1R F;  5C4J F;  3RZD F;  4KN4 E;  4A3C F;  3EQL E;  2R92 F;  5IYB F;  2YU9 F;  4Q4Z E;  5D4C E;  4MEX E;  3GTL F;  4A3M F;  1TWC F;  3M3Y F;  2A6H E;  3K7A F;  2JA6 F;  2WB1 I;  4A3J F;  5TMF E;  1I6H F; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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