4NTWB

Structure of acid-sensing ion channel in complex with snake toxin
Total Genus 14
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
14
sequence length
60
structure length
60
Chain Sequence
EIRPAFCYEDPPFFQKCGAFVDSYYFNRSRITCVHFFYGQCDVNQNHFTTMSECNRVCHG
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title X-ray structure of Acid-sensing ion channel 1-snake toxin complex reveals open state of a na(+)-selective channel.
pubmed doi rcsb
molecule tags Transport protein/toxin
source organism Gallus gallus
molecule keywords Acid-sensing ion channel 1
total genus 14
structure length 60
sequence length 60
ec nomenclature
pdb deposition date 2013-12-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00014 Kunitz_BPTI Kunitz/Bovine pancreatic trypsin inhibitor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.410.10 Few Secondary Structures Irregular Factor Xa Inhibitor Pancreatic trypsin inhibitor Kunitz domain 4ntwB00
2LFKA 3BTMI 1BRCI 1G6XA 1YC0I 4ISOB 1IRHA 2TGPI 4ISLB 6PTIA 5JB5A 4DG4C 2W8XA 1BPTA 1PITA 2FI4I 2FTMB 1CO7I 4NTXB 4NTWB 2HEXA 1BZXI 4NTYB 1B0CA 1OA65 3U1JE 1TCPA 1YLDB 7PTIA 3AUHA 3M7QB 2UUXA 3OTJI 3P92E 1P2MB 3BTKI 3L33E 4Y10I 2M99A 1CA0D 2IJOI 2FTLI 4WXVC 1T7CB 1ZJDB 3FP8I 5PTIA 4Y0YI 4Y11I 3LDMA 3AUGA 1T8MB 1TOCR 1P2OB 3BTHI 1DENA 2KCRA 3AUDA 3UOUB 2DDIA 3TPII 8PTIA 1NAGA 1P2NB 4WWYC 1KUNA 1P2QB 2ZVXA 2J6DA 1P2JI 1MTND 3T62D 3BTFI 1F7ZI 1BRBI 4PTIA 1JC6A 1BZ5A 3LDIA 3BTGI 2TPII 1FY8I 9PTIA 1Y62A 3UIRC 2KNTA 1LD6A 1AALA 4DTGK 2ODYE 1DTKA 3CI7A 4TPII 3TGII 3BYBA 1QLQA 1KTHA 1CBWD 1OA55 1ZR0B 1BHCA 5JB7A 1BF0A 2CA7A 1UUBA 1T8OB 1LD5A 4BD9B 2FI5I 1DTXA 3AUIA 1BUNB 5JB6A 2KAII 2FI3I 2RA3C 1UUAA 3BTEI 1D0DB 1D0DA 1EJMB 3BTTI 3OFWA 4ISNB 1T8NB 3TGKI 1KNTA 2JOTA 3AUCA 1F5RI 3AUBA 3BTQI 3FP6I 4U32X 1ADZA 1P2KI 2DDJA 2UUYB 1DEMA 1FAKI 1EAWB 1BTHP 1K6UA 2ZJXA 3AUEA 5C67C 1YLCB 1AAPA 3BTDI 1P2II 3BTWI 1JV9A 4U30W 1TFXC 1T8LB 1BIKA 1FANA 1TAPA 3TGJI 4BNRI 1SHPA 1JV8A 5JB4A 3D65I 1BTIA 2M01A 3WNYA 3FP7J 1BPIA 3L3TE 1TPAI 4BQDA 3LDJA 3P95E 1KIGI 4Y0ZI 2PTCI 1YKTB 2R9PE 3GYMI 2LFLA 1TAWB
chains in the Genus database with same CATH superfamily
2LFKA 3BTMI 1BRCI 1G6XA 1YC0I 4ISOB 1IRHA 2TGPI 4ISLB 6PTIA 5JB5A 4DG4C 2W8XA 1BPTA 1PITA 2FI4I 2FTMB 1CO7I 4NTXB 4NTWB 2HEXA 1BZXI 4NTYB 1B0CA 1OA65 3U1JE 1TCPA 1YLDB 7PTIA 3AUHA 3M7QB 2UUXA 3OTJI 3P92E 1P2MB 3BTKI 3L33E 4Y10I 2M99A 1CA0D 2IJOI 2FTLI 4WXVC 1T7CB 1ZJDB 3FP8I 5PTIA 4Y0YI 4Y11I 3LDMA 3AUGA 1T8MB 1TOCR 1P2OB 3BTHI 1DENA 2KCRA 3AUDA 3UOUB 2DDIA 3TPII 8PTIA 1NAGA 1P2NB 4WWYC 1KUNA 1P2QB 2ZVXA 2J6DA 1P2JI 1MTND 3T62D 3BTFI 1F7ZI 1BRBI 4PTIA 1JC6A 1BZ5A 3LDIA 3BTGI 2TPII 1FY8I 9PTIA 1Y62A 3UIRC 2KNTA 1LD6A 1AALA 4DTGK 2ODYE 1DTKA 3CI7A 4TPII 3TGII 3BYBA 1QLQA 1KTHA 1CBWD 1OA55 1ZR0B 1BHCA 5JB7A 1BF0A 2CA7A 1UUBA 1T8OB 1LD5A 4BD9B 2FI5I 1DTXA 3AUIA 1BUNB 5JB6A 2KAII 2FI3I 2RA3C 1UUAA 3BTEI 1D0DB 1D0DA 1EJMB 3BTTI 3OFWA 4ISNB 1T8NB 3TGKI 1KNTA 2JOTA 3AUCA 1F5RI 3AUBA 3BTQI 3FP6I 4U32X 1ADZA 1P2KI 2DDJA 2UUYB 1DEMA 1FAKI 1EAWB 1BTHP 1K6UA 2ZJXA 3AUEA 5C67C 1YLCB 1AAPA 3BTDI 1P2II 3BTWI 1JV9A 4U30W 1TFXC 1T8LB 1BIKA 1FANA 1TAPA 3TGJI 4BNRI 1SHPA 1JV8A 5JB4A 3D65I 1BTIA 2M01A 3WNYA 3FP7J 1BPIA 3L3TE 1TPAI 4BQDA 3LDJA 3P95E 1KIGI 4Y0ZI 2PTCI 1YKTB 2R9PE 3GYMI 2LFLA 1TAWB
chains in the Genus database with same CATH topology
2LFKA 3BTMI 1BRCI 1G6XA 1YC0I 4ISOB 1IRHA 2TGPI 4ISLB 6PTIA 5JB5A 4DG4C 2W8XA 1BPTA 1PITA 2FI4I 2FTMB 1CO7I 4NTXB 4NTWB 2HEXA 1BZXI 4NTYB 1B0CA 1OA65 3U1JE 1TCPA 1YLDB 7PTIA 3AUHA 3M7QB 2UUXA 3OTJI 3P92E 1P2MB 3BTKI 3L33E 4Y10I 2M99A 1CA0D 2IJOI 2FTLI 4WXVC 1T7CB 1ZJDB 3FP8I 5PTIA 4Y0YI 4Y11I 3LDMA 3AUGA 1T8MB 1TOCR 1P2OB 3BTHI 1DENA 2KCRA 3AUDA 3UOUB 2DDIA 3TPII 8PTIA 1NAGA 1P2NB 4WWYC 1KUNA 1P2QB 2ZVXA 2J6DA 1P2JI 1MTND 3T62D 3BTFI 1F7ZI 1BRBI 4PTIA 1JC6A 1BZ5A 3LDIA 3BTGI 2TPII 1FY8I 9PTIA 1Y62A 3UIRC 2KNTA 1LD6A 1AALA 4DTGK 2ODYE 1DTKA 3CI7A 4TPII 3TGII 3BYBA 1QLQA 1KTHA 1CBWD 1OA55 1ZR0B 1BHCA 5JB7A 1BF0A 2CA7A 1UUBA 1T8OB 1LD5A 4BD9B 2FI5I 1DTXA 3AUIA 1BUNB 5JB6A 2KAII 2FI3I 2RA3C 1UUAA 3BTEI 1D0DB 1D0DA 1EJMB 3BTTI 3OFWA 4ISNB 1T8NB 3TGKI 1KNTA 2JOTA 3AUCA 1F5RI 3AUBA 3BTQI 3FP6I 4U32X 1ADZA 1P2KI 2DDJA 2UUYB 1DEMA 1FAKI 1EAWB 1BTHP 1K6UA 2ZJXA 3AUEA 5C67C 1YLCB 1AAPA 3BTDI 1P2II 3BTWI 1JV9A 4U30W 1TFXC 1T8LB 1BIKA 1FANA 1TAPA 3TGJI 4BNRI 1SHPA 1JV8A 5JB4A 3D65I 1BTIA 2M01A 3WNYA 3FP7J 1BPIA 3L3TE 1TPAI 4BQDA 3LDJA 3P95E 1KIGI 4Y0ZI 2PTCI 1YKTB 2R9PE 3GYMI 2LFLA 1TAWB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2LFK A;  3BTM I;  1BRC I;  1G6X A;  1YC0 I;  4ISO B;  1IRH A;  2TGP I;  4ISL B;  6PTI A;  5JB5 A;  4DG4 C;  2W8X A;  1BPT A;  1PIT A;  2FI4 I;  2FTM B;  1CO7 I;  4NTX B;  4NTW B;  2HEX A;  1BZX I;  4NTY B;  1B0C A;  1OA6 5;  3U1J E;  1TCP A;  1YLD B;  7PTI A;  3AUH A;  3M7Q B;  2UUX A;  3OTJ I;  3P92 E;  1P2M B;  3BTK I;  3L33 E;  4Y10 I;  2M99 A;  1CA0 D;  2IJO I;  2FTL I;  4WXV C;  1T7C B;  1ZJD B;  3FP8 I;  5PTI A;  4Y0Y I;  4Y11 I;  3LDM A;  3AUG A;  1T8M B;  1TOC R;  1P2O B;  3BTH I;  1DEN A;  2KCR A;  3AUD A;  3UOU B;  2DDI A;  3TPI I;  8PTI A;  1NAG A;  1P2N B;  4WWY C;  1KUN A;  1P2Q B;  2ZVX A;  2J6D A;  1P2J I;  1MTN D;  3T62 D;  3BTF I;  1F7Z I;  1BRB I;  4PTI A;  1JC6 A;  1BZ5 A;  3LDI A;  3BTG I;  2TPI I;  1FY8 I;  9PTI A;  1Y62 A;  3UIR C;  2KNT A;  1LD6 A;  1AAL A;  4DTG K;  2ODY E;  1DTK A;  3CI7 A;  4TPI I;  3TGI I;  3BYB A;  1QLQ A;  1KTH A;  1CBW D;  1OA5 5;  1ZR0 B;  1BHC A;  5JB7 A;  1BF0 A;  2CA7 A;  1UUB A;  1T8O B;  1LD5 A;  4BD9 B;  2FI5 I;  1DTX A;  3AUI A;  1BUN B;  5JB6 A;  2KAI I;  2FI3 I;  2RA3 C;  1UUA A;  3BTE I;  1D0D B;  1D0D A;  1EJM B;  3BTT I;  3OFW A;  4ISN B;  1T8N B;  3TGK I;  1KNT A;  2JOT A;  3AUC A;  1F5R I;  3AUB A;  3BTQ I;  3FP6 I;  4U32 X;  1ADZ A;  1P2K I;  2DDJ A;  2UUY B;  1DEM A;  1FAK I;  1EAW B;  1BTH P;  1K6U A;  2ZJX A;  3AUE A;  5C67 C;  1YLC B;  1AAP A;  3BTD I;  1P2I I;  3BTW I;  1JV9 A;  4U30 W;  1TFX C;  1T8L B;  1BIK A;  1FAN A;  1TAP A;  3TGJ I;  4BNR I;  1SHP A;  1JV8 A;  5JB4 A;  3D65 I;  1BTI A;  2M01 A;  3WNY A;  3FP7 J;  1BPI A;  3L3T E;  1TPA I;  4BQD A;  3LDJ A;  3P95 E;  1KIG I;  4Y0Z I;  2PTC I;  1YKT B;  2R9P E;  3GYM I;  2LFL A;  1TAW B; 
#chains in the Genus database with same CATH topology
 2LFK A;  3BTM I;  1BRC I;  1G6X A;  1YC0 I;  4ISO B;  1IRH A;  2TGP I;  4ISL B;  6PTI A;  5JB5 A;  4DG4 C;  2W8X A;  1BPT A;  1PIT A;  2FI4 I;  2FTM B;  1CO7 I;  4NTX B;  4NTW B;  2HEX A;  1BZX I;  4NTY B;  1B0C A;  1OA6 5;  3U1J E;  1TCP A;  1YLD B;  7PTI A;  3AUH A;  3M7Q B;  2UUX A;  3OTJ I;  3P92 E;  1P2M B;  3BTK I;  3L33 E;  4Y10 I;  2M99 A;  1CA0 D;  2IJO I;  2FTL I;  4WXV C;  1T7C B;  1ZJD B;  3FP8 I;  5PTI A;  4Y0Y I;  4Y11 I;  3LDM A;  3AUG A;  1T8M B;  1TOC R;  1P2O B;  3BTH I;  1DEN A;  2KCR A;  3AUD A;  3UOU B;  2DDI A;  3TPI I;  8PTI A;  1NAG A;  1P2N B;  4WWY C;  1KUN A;  1P2Q B;  2ZVX A;  2J6D A;  1P2J I;  1MTN D;  3T62 D;  3BTF I;  1F7Z I;  1BRB I;  4PTI A;  1JC6 A;  1BZ5 A;  3LDI A;  3BTG I;  2TPI I;  1FY8 I;  9PTI A;  1Y62 A;  3UIR C;  2KNT A;  1LD6 A;  1AAL A;  4DTG K;  2ODY E;  1DTK A;  3CI7 A;  4TPI I;  3TGI I;  3BYB A;  1QLQ A;  1KTH A;  1CBW D;  1OA5 5;  1ZR0 B;  1BHC A;  5JB7 A;  1BF0 A;  2CA7 A;  1UUB A;  1T8O B;  1LD5 A;  4BD9 B;  2FI5 I;  1DTX A;  3AUI A;  1BUN B;  5JB6 A;  2KAI I;  2FI3 I;  2RA3 C;  1UUA A;  3BTE I;  1D0D B;  1D0D A;  1EJM B;  3BTT I;  3OFW A;  4ISN B;  1T8N B;  3TGK I;  1KNT A;  2JOT A;  3AUC A;  1F5R I;  3AUB A;  3BTQ I;  3FP6 I;  4U32 X;  1ADZ A;  1P2K I;  2DDJ A;  2UUY B;  1DEM A;  1FAK I;  1EAW B;  1BTH P;  1K6U A;  2ZJX A;  3AUE A;  5C67 C;  1YLC B;  1AAP A;  3BTD I;  1P2I I;  3BTW I;  1JV9 A;  4U30 W;  1TFX C;  1T8L B;  1BIK A;  1FAN A;  1TAP A;  3TGJ I;  4BNR I;  1SHP A;  1JV8 A;  5JB4 A;  3D65 I;  1BTI A;  2M01 A;  3WNY A;  3FP7 J;  1BPI A;  3L3T E;  1TPA I;  4BQD A;  3LDJ A;  3P95 E;  1KIG I;  4Y0Z I;  2PTC I;  1YKT B;  2R9P E;  3GYM I;  2LFL A;  1TAW B; 
#chains in the Genus database with same CATH homology
 2LFK A;  3BTM I;  1BRC I;  1G6X A;  1YC0 I;  4ISO B;  1IRH A;  2TGP I;  4ISL B;  6PTI A;  5JB5 A;  4DG4 C;  2W8X A;  1BPT A;  1PIT A;  2FI4 I;  2FTM B;  1CO7 I;  4NTX B;  4NTW B;  2HEX A;  1BZX I;  4NTY B;  1B0C A;  1OA6 5;  3U1J E;  1TCP A;  1YLD B;  7PTI A;  3AUH A;  3M7Q B;  2UUX A;  3OTJ I;  3P92 E;  1P2M B;  3BTK I;  3L33 E;  4Y10 I;  2M99 A;  1CA0 D;  2IJO I;  2FTL I;  4WXV C;  1T7C B;  1ZJD B;  3FP8 I;  5PTI A;  4Y0Y I;  4Y11 I;  3LDM A;  3AUG A;  1T8M B;  1TOC R;  1P2O B;  3BTH I;  1DEN A;  2KCR A;  3AUD A;  3UOU B;  2DDI A;  3TPI I;  8PTI A;  1NAG A;  1P2N B;  4WWY C;  1KUN A;  1P2Q B;  2ZVX A;  2J6D A;  1P2J I;  1MTN D;  3T62 D;  3BTF I;  1F7Z I;  1BRB I;  4PTI A;  1JC6 A;  1BZ5 A;  3LDI A;  3BTG I;  2TPI I;  1FY8 I;  9PTI A;  1Y62 A;  3UIR C;  2KNT A;  1LD6 A;  1AAL A;  4DTG K;  2ODY E;  1DTK A;  3CI7 A;  4TPI I;  3TGI I;  3BYB A;  1QLQ A;  1KTH A;  1CBW D;  1OA5 5;  1ZR0 B;  1BHC A;  5JB7 A;  1BF0 A;  2CA7 A;  1UUB A;  1T8O B;  1LD5 A;  4BD9 B;  2FI5 I;  1DTX A;  3AUI A;  1BUN B;  5JB6 A;  2KAI I;  2FI3 I;  2RA3 C;  1UUA A;  3BTE I;  1D0D B;  1D0D A;  1EJM B;  3BTT I;  3OFW A;  4ISN B;  1T8N B;  3TGK I;  1KNT A;  2JOT A;  3AUC A;  1F5R I;  3AUB A;  3BTQ I;  3FP6 I;  4U32 X;  1ADZ A;  1P2K I;  2DDJ A;  2UUY B;  1DEM A;  1FAK I;  1EAW B;  1BTH P;  1K6U A;  2ZJX A;  3AUE A;  5C67 C;  1YLC B;  1AAP A;  3BTD I;  1P2I I;  3BTW I;  1JV9 A;  4U30 W;  1TFX C;  1T8L B;  1BIK A;  1FAN A;  1TAP A;  3TGJ I;  4BNR I;  1SHP A;  1JV8 A;  5JB4 A;  3D65 I;  1BTI A;  2M01 A;  3WNY A;  3FP7 J;  1BPI A;  3L3T E;  1TPA I;  4BQD A;  3LDJ A;  3P95 E;  1KIG I;  4Y0Z I;  2PTC I;  1YKT B;  2R9P E;  3GYM I;  2LFL A;  1TAW B; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...