4NTYB

Cesium sites in the crystal structure of acid-sensing ion channel in complex with snake toxin
Total Genus 10
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
10
sequence length
60
structure length
60
Chain Sequence
EIRPAFCYEDPPFFQKCGAFVDSYYFNRSRITCVHFFYGQCDVNQNHFTTMSECNRVCHG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title X-ray structure of Acid-sensing ion channel 1-snake toxin complex reveals open state of a na(+)-selective channel.
pubmed doi rcsb
molecule tags Transport protein/toxin
source organism Gallus gallus
molecule keywords Acid-sensing ion channel 1
total genus 10
structure length 60
sequence length 60
ec nomenclature
pdb deposition date 2013-12-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00014 Kunitz_BPTI Kunitz/Bovine pancreatic trypsin inhibitor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.410.10 Few Secondary Structures Irregular Factor Xa Inhibitor Pancreatic trypsin inhibitor Kunitz domain 4ntyB00
1AAPA 3TGKI 1DTKA 1BUNB 2FI4I 5JB6A 2UUYB 2ODYE 4NTWB 3T62D 5JB4A 4DG4C 3BYBA 2TPII 1YLCB 2TGPI 4BNRI 1CO7I 1ADZA 3TPII 3LDJA 1DEMA 4NTYB 4BQDA 3M7QB 3GYMI 3AUBA 4ISNB 1BZXI 1KIGI 3FP7J 2JOTA 3D65I 1F5RI 4U30W 4PTIA 3TGII 1EAWB 1T8MB 1DENA 4Y0YI 3WNYA 1P2MB 4NTXB 3AUCA 1YC0I 9PTIA 1KNTA 2W8XA 2M99A 2KCRA 3AUHA 1TOCR 1FY8I 3BTDI 1OA55 2M01A 1TPAI 1PITA 1UUAA 1P2KI 1P2JI 2RA3C 3P92E 3AUDA 1K6UA 3BTKI 3P95E 4BD9B 3CI7A 1D0DA 1T8OB 1CBWD 1AALA 2LFKA 3BTHI 7PTIA 6PTIA 1BTHP 4WXVC 1P2NB 1MTND 1SHPA 1DTXA 1JV8A 2R9PE 3FP6I 2LFLA 2IJOI 1BF0A 4Y11I 3FP8I 1NAGA 1ZR0B 2ZJXA 3BTGI 4WWYC 5JB7A 1P2II 4U32X 3BTQI 1BTIA 4Y10I 1T7CB 4Y0ZI 3AUGA 3L3TE 1FAKI 2PTCI 3LDMA 3UIRC 1TCPA 4ISLB 1D0DB 2DDIA 2KNTA 2DDJA 2FTMB 4TPII 5PTIA 1BPIA 1F7ZI 1P2QB 1YKTB 5JB5A 8PTIA 2FI5I 1JC6A 1JV9A 1OA65 1KUNA 3OFWA 3LDIA 5C67C 2HEXA 3AUIA 1G6XA 3L33E 1IRHA 1B0CA 1YLDB 3BTEI 3U1JE 3TGJI 1Y62A 3AUEA 1BPTA 1LD5A 1BRCI 2FTLI 1ZJDB 1BHCA 3BTWI 1KTHA 1TFXC 1TAWB 1P2OB 3BTFI 2CA7A 3BTTI 1UUBA 2ZVXA 2J6DA 1LD6A 3BTMI 1BIKA 1BRBI 1EJMB 2UUXA 3UOUB 1T8LB 1TAPA 4ISOB 1CA0D 1T8NB 4DTGK 2KAII 1BZ5A 1QLQA 3OTJI 1FANA 2FI3I
chains in the Genus database with same CATH superfamily
1AAPA 3TGKI 1DTKA 1BUNB 2FI4I 5JB6A 2UUYB 2ODYE 4NTWB 3T62D 5JB4A 4DG4C 3BYBA 2TPII 1YLCB 2TGPI 4BNRI 1CO7I 1ADZA 3TPII 3LDJA 1DEMA 4NTYB 4BQDA 3M7QB 3GYMI 3AUBA 4ISNB 1BZXI 1KIGI 3FP7J 2JOTA 3D65I 1F5RI 4U30W 4PTIA 3TGII 1EAWB 1T8MB 1DENA 4Y0YI 3WNYA 1P2MB 4NTXB 3AUCA 1YC0I 9PTIA 1KNTA 2W8XA 2M99A 2KCRA 3AUHA 1TOCR 1FY8I 3BTDI 1OA55 2M01A 1TPAI 1PITA 1UUAA 1P2KI 1P2JI 2RA3C 3P92E 3AUDA 1K6UA 3BTKI 3P95E 4BD9B 3CI7A 1D0DA 1T8OB 1CBWD 1AALA 2LFKA 3BTHI 7PTIA 6PTIA 1BTHP 4WXVC 1P2NB 1MTND 1SHPA 1DTXA 1JV8A 2R9PE 3FP6I 2LFLA 2IJOI 1BF0A 4Y11I 3FP8I 1NAGA 1ZR0B 2ZJXA 3BTGI 4WWYC 5JB7A 1P2II 4U32X 3BTQI 1BTIA 4Y10I 1T7CB 4Y0ZI 3AUGA 3L3TE 1FAKI 2PTCI 3LDMA 3UIRC 1TCPA 4ISLB 1D0DB 2DDIA 2KNTA 2DDJA 2FTMB 4TPII 5PTIA 1BPIA 1F7ZI 1P2QB 1YKTB 5JB5A 8PTIA 2FI5I 1JC6A 1JV9A 1OA65 1KUNA 3OFWA 3LDIA 5C67C 2HEXA 3AUIA 1G6XA 3L33E 1IRHA 1B0CA 1YLDB 3BTEI 3U1JE 3TGJI 1Y62A 3AUEA 1BPTA 1LD5A 1BRCI 2FTLI 1ZJDB 1BHCA 3BTWI 1KTHA 1TFXC 1TAWB 1P2OB 3BTFI 2CA7A 3BTTI 1UUBA 2ZVXA 2J6DA 1LD6A 3BTMI 1BIKA 1BRBI 1EJMB 2UUXA 3UOUB 1T8LB 1TAPA 4ISOB 1CA0D 1T8NB 4DTGK 2KAII 1BZ5A 1QLQA 3OTJI 1FANA 2FI3I
chains in the Genus database with same CATH topology
1AAPA 3TGKI 1DTKA 1BUNB 2FI4I 5JB6A 2UUYB 2ODYE 4NTWB 3T62D 5JB4A 4DG4C 3BYBA 2TPII 1YLCB 2TGPI 4BNRI 1CO7I 1ADZA 3TPII 3LDJA 1DEMA 4NTYB 4BQDA 3M7QB 3GYMI 3AUBA 4ISNB 1BZXI 1KIGI 3FP7J 2JOTA 3D65I 1F5RI 4U30W 4PTIA 3TGII 1EAWB 1T8MB 1DENA 4Y0YI 3WNYA 1P2MB 4NTXB 3AUCA 1YC0I 9PTIA 1KNTA 2W8XA 2M99A 2KCRA 3AUHA 1TOCR 1FY8I 3BTDI 1OA55 2M01A 1TPAI 1PITA 1UUAA 1P2KI 1P2JI 2RA3C 3P92E 3AUDA 1K6UA 3BTKI 3P95E 4BD9B 3CI7A 1D0DA 1T8OB 1CBWD 1AALA 2LFKA 3BTHI 7PTIA 6PTIA 1BTHP 4WXVC 1P2NB 1MTND 1SHPA 1DTXA 1JV8A 2R9PE 3FP6I 2LFLA 2IJOI 1BF0A 4Y11I 3FP8I 1NAGA 1ZR0B 2ZJXA 3BTGI 4WWYC 5JB7A 1P2II 4U32X 3BTQI 1BTIA 4Y10I 1T7CB 4Y0ZI 3AUGA 3L3TE 1FAKI 2PTCI 3LDMA 3UIRC 1TCPA 4ISLB 1D0DB 2DDIA 2KNTA 2DDJA 2FTMB 4TPII 5PTIA 1BPIA 1F7ZI 1P2QB 1YKTB 5JB5A 8PTIA 2FI5I 1JC6A 1JV9A 1OA65 1KUNA 3OFWA 3LDIA 5C67C 2HEXA 3AUIA 1G6XA 3L33E 1IRHA 1B0CA 1YLDB 3BTEI 3U1JE 3TGJI 1Y62A 3AUEA 1BPTA 1LD5A 1BRCI 2FTLI 1ZJDB 1BHCA 3BTWI 1KTHA 1TFXC 1TAWB 1P2OB 3BTFI 2CA7A 3BTTI 1UUBA 2ZVXA 2J6DA 1LD6A 3BTMI 1BIKA 1BRBI 1EJMB 2UUXA 3UOUB 1T8LB 1TAPA 4ISOB 1CA0D 1T8NB 4DTGK 2KAII 1BZ5A 1QLQA 3OTJI 1FANA 2FI3I
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1AAP A;  3TGK I;  1DTK A;  1BUN B;  2FI4 I;  5JB6 A;  2UUY B;  2ODY E;  4NTW B;  3T62 D;  5JB4 A;  4DG4 C;  3BYB A;  2TPI I;  1YLC B;  2TGP I;  4BNR I;  1CO7 I;  1ADZ A;  3TPI I;  3LDJ A;  1DEM A;  4NTY B;  4BQD A;  3M7Q B;  3GYM I;  3AUB A;  4ISN B;  1BZX I;  1KIG I;  3FP7 J;  2JOT A;  3D65 I;  1F5R I;  4U30 W;  4PTI A;  3TGI I;  1EAW B;  1T8M B;  1DEN A;  4Y0Y I;  3WNY A;  1P2M B;  4NTX B;  3AUC A;  1YC0 I;  9PTI A;  1KNT A;  2W8X A;  2M99 A;  2KCR A;  3AUH A;  1TOC R;  1FY8 I;  3BTD I;  1OA5 5;  2M01 A;  1TPA I;  1PIT A;  1UUA A;  1P2K I;  1P2J I;  2RA3 C;  3P92 E;  3AUD A;  1K6U A;  3BTK I;  3P95 E;  4BD9 B;  3CI7 A;  1D0D A;  1T8O B;  1CBW D;  1AAL A;  2LFK A;  3BTH I;  7PTI A;  6PTI A;  1BTH P;  4WXV C;  1P2N B;  1MTN D;  1SHP A;  1DTX A;  1JV8 A;  2R9P E;  3FP6 I;  2LFL A;  2IJO I;  1BF0 A;  4Y11 I;  3FP8 I;  1NAG A;  1ZR0 B;  2ZJX A;  3BTG I;  4WWY C;  5JB7 A;  1P2I I;  4U32 X;  3BTQ I;  1BTI A;  4Y10 I;  1T7C B;  4Y0Z I;  3AUG A;  3L3T E;  1FAK I;  2PTC I;  3LDM A;  3UIR C;  1TCP A;  4ISL B;  1D0D B;  2DDI A;  2KNT A;  2DDJ A;  2FTM B;  4TPI I;  5PTI A;  1BPI A;  1F7Z I;  1P2Q B;  1YKT B;  5JB5 A;  8PTI A;  2FI5 I;  1JC6 A;  1JV9 A;  1OA6 5;  1KUN A;  3OFW A;  3LDI A;  5C67 C;  2HEX A;  3AUI A;  1G6X A;  3L33 E;  1IRH A;  1B0C A;  1YLD B;  3BTE I;  3U1J E;  3TGJ I;  1Y62 A;  3AUE A;  1BPT A;  1LD5 A;  1BRC I;  2FTL I;  1ZJD B;  1BHC A;  3BTW I;  1KTH A;  1TFX C;  1TAW B;  1P2O B;  3BTF I;  2CA7 A;  3BTT I;  1UUB A;  2ZVX A;  2J6D A;  1LD6 A;  3BTM I;  1BIK A;  1BRB I;  1EJM B;  2UUX A;  3UOU B;  1T8L B;  1TAP A;  4ISO B;  1CA0 D;  1T8N B;  4DTG K;  2KAI I;  1BZ5 A;  1QLQ A;  3OTJ I;  1FAN A;  2FI3 I; 
#chains in the Genus database with same CATH topology
 1AAP A;  3TGK I;  1DTK A;  1BUN B;  2FI4 I;  5JB6 A;  2UUY B;  2ODY E;  4NTW B;  3T62 D;  5JB4 A;  4DG4 C;  3BYB A;  2TPI I;  1YLC B;  2TGP I;  4BNR I;  1CO7 I;  1ADZ A;  3TPI I;  3LDJ A;  1DEM A;  4NTY B;  4BQD A;  3M7Q B;  3GYM I;  3AUB A;  4ISN B;  1BZX I;  1KIG I;  3FP7 J;  2JOT A;  3D65 I;  1F5R I;  4U30 W;  4PTI A;  3TGI I;  1EAW B;  1T8M B;  1DEN A;  4Y0Y I;  3WNY A;  1P2M B;  4NTX B;  3AUC A;  1YC0 I;  9PTI A;  1KNT A;  2W8X A;  2M99 A;  2KCR A;  3AUH A;  1TOC R;  1FY8 I;  3BTD I;  1OA5 5;  2M01 A;  1TPA I;  1PIT A;  1UUA A;  1P2K I;  1P2J I;  2RA3 C;  3P92 E;  3AUD A;  1K6U A;  3BTK I;  3P95 E;  4BD9 B;  3CI7 A;  1D0D A;  1T8O B;  1CBW D;  1AAL A;  2LFK A;  3BTH I;  7PTI A;  6PTI A;  1BTH P;  4WXV C;  1P2N B;  1MTN D;  1SHP A;  1DTX A;  1JV8 A;  2R9P E;  3FP6 I;  2LFL A;  2IJO I;  1BF0 A;  4Y11 I;  3FP8 I;  1NAG A;  1ZR0 B;  2ZJX A;  3BTG I;  4WWY C;  5JB7 A;  1P2I I;  4U32 X;  3BTQ I;  1BTI A;  4Y10 I;  1T7C B;  4Y0Z I;  3AUG A;  3L3T E;  1FAK I;  2PTC I;  3LDM A;  3UIR C;  1TCP A;  4ISL B;  1D0D B;  2DDI A;  2KNT A;  2DDJ A;  2FTM B;  4TPI I;  5PTI A;  1BPI A;  1F7Z I;  1P2Q B;  1YKT B;  5JB5 A;  8PTI A;  2FI5 I;  1JC6 A;  1JV9 A;  1OA6 5;  1KUN A;  3OFW A;  3LDI A;  5C67 C;  2HEX A;  3AUI A;  1G6X A;  3L33 E;  1IRH A;  1B0C A;  1YLD B;  3BTE I;  3U1J E;  3TGJ I;  1Y62 A;  3AUE A;  1BPT A;  1LD5 A;  1BRC I;  2FTL I;  1ZJD B;  1BHC A;  3BTW I;  1KTH A;  1TFX C;  1TAW B;  1P2O B;  3BTF I;  2CA7 A;  3BTT I;  1UUB A;  2ZVX A;  2J6D A;  1LD6 A;  3BTM I;  1BIK A;  1BRB I;  1EJM B;  2UUX A;  3UOU B;  1T8L B;  1TAP A;  4ISO B;  1CA0 D;  1T8N B;  4DTG K;  2KAI I;  1BZ5 A;  1QLQ A;  3OTJ I;  1FAN A;  2FI3 I; 
#chains in the Genus database with same CATH homology
 1AAP A;  3TGK I;  1DTK A;  1BUN B;  2FI4 I;  5JB6 A;  2UUY B;  2ODY E;  4NTW B;  3T62 D;  5JB4 A;  4DG4 C;  3BYB A;  2TPI I;  1YLC B;  2TGP I;  4BNR I;  1CO7 I;  1ADZ A;  3TPI I;  3LDJ A;  1DEM A;  4NTY B;  4BQD A;  3M7Q B;  3GYM I;  3AUB A;  4ISN B;  1BZX I;  1KIG I;  3FP7 J;  2JOT A;  3D65 I;  1F5R I;  4U30 W;  4PTI A;  3TGI I;  1EAW B;  1T8M B;  1DEN A;  4Y0Y I;  3WNY A;  1P2M B;  4NTX B;  3AUC A;  1YC0 I;  9PTI A;  1KNT A;  2W8X A;  2M99 A;  2KCR A;  3AUH A;  1TOC R;  1FY8 I;  3BTD I;  1OA5 5;  2M01 A;  1TPA I;  1PIT A;  1UUA A;  1P2K I;  1P2J I;  2RA3 C;  3P92 E;  3AUD A;  1K6U A;  3BTK I;  3P95 E;  4BD9 B;  3CI7 A;  1D0D A;  1T8O B;  1CBW D;  1AAL A;  2LFK A;  3BTH I;  7PTI A;  6PTI A;  1BTH P;  4WXV C;  1P2N B;  1MTN D;  1SHP A;  1DTX A;  1JV8 A;  2R9P E;  3FP6 I;  2LFL A;  2IJO I;  1BF0 A;  4Y11 I;  3FP8 I;  1NAG A;  1ZR0 B;  2ZJX A;  3BTG I;  4WWY C;  5JB7 A;  1P2I I;  4U32 X;  3BTQ I;  1BTI A;  4Y10 I;  1T7C B;  4Y0Z I;  3AUG A;  3L3T E;  1FAK I;  2PTC I;  3LDM A;  3UIR C;  1TCP A;  4ISL B;  1D0D B;  2DDI A;  2KNT A;  2DDJ A;  2FTM B;  4TPI I;  5PTI A;  1BPI A;  1F7Z I;  1P2Q B;  1YKT B;  5JB5 A;  8PTI A;  2FI5 I;  1JC6 A;  1JV9 A;  1OA6 5;  1KUN A;  3OFW A;  3LDI A;  5C67 C;  2HEX A;  3AUI A;  1G6X A;  3L33 E;  1IRH A;  1B0C A;  1YLD B;  3BTE I;  3U1J E;  3TGJ I;  1Y62 A;  3AUE A;  1BPT A;  1LD5 A;  1BRC I;  2FTL I;  1ZJD B;  1BHC A;  3BTW I;  1KTH A;  1TFX C;  1TAW B;  1P2O B;  3BTF I;  2CA7 A;  3BTT I;  1UUB A;  2ZVX A;  2J6D A;  1LD6 A;  3BTM I;  1BIK A;  1BRB I;  1EJM B;  2UUX A;  3UOU B;  1T8L B;  1TAP A;  4ISO B;  1CA0 D;  1T8N B;  4DTG K;  2KAI I;  1BZ5 A;  1QLQ A;  3OTJ I;  1FAN A;  2FI3 I; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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