4Q4ZE

Thermus thermophilus rna polymerase de novo transcription initiation complex
Total Genus 26
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
26
sequence length
94
structure length
94
Chain Sequence
AEPGIDKLFGMVDSKYRLTVVVAKRAQQLLRHGFKNTVLEPEERPKMQTLEGLFDDPNAVTWAMKELLTGRLVFGENLVPEDRLQKEMERLYPV
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of transcription initiation by bacterial RNA polymerase holoenzyme.
pubmed doi rcsb
molecule tags Transcription/dna
source organism Thermus thermophilus
molecule keywords DNA-directed RNA polymerase subunit alpha
total genus 26
structure length 94
sequence length 94
ec nomenclature ec 2.7.7.6: DNA-directed RNA polymerase.
pdb deposition date 2014-04-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF01192 RNA_pol_Rpb6 RNA polymerase Rpb6
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.940.10 Alpha Beta Alpha-Beta Complex Eukaryotic RPB6 RNA polymerase subunit Eukaryotic RPB6 RNA polymerase subunit 4q4zE00
3S1NF 5M3MF 3S16F 3DXJE 2E2HF 4YFKE 1I6HF 3HOVF 2Y0SI 4A3FF 1I6VE 4A93F 4Y7NF 5E18E 2A6HE 4XSXE 2BE5E 5IYCF 2A68E 1QKLA 3CQZF 1HQME 4JK1E 3S1QF 3GTQF 5IP7F 5IP9F 4OIPE 4C3HF 4MEYE 2NVTF 3EQLE 4Q5SE 4GZYE 3RZDF 2JA8F 4A3KF 1YNJK 1I50F 2CW0E 3PO3F 4BXXF 4G7ZE 3FKIF 4LK1E 4A3LF 5M5XF 4C3JF 2R93F 3GTGF 4YFXE 4A3JF 4Q4ZE 4A3EF 5D4DE 3I4NF 1TWFF 3GTPF 3PO2F 1I3QF 4OINE 3S1MF 1K83F 4KN7E 4X6AF 1R9TF 5M3FF 1SFOF 3H3VG 2JA7F 4LLGE 4MEXE 3GTLF 3GTMF 3GTOF 4A3BF 2R92F 4BY7F 4BBSF 4A3DF 1ZYRE 4KMUE 1YNNK 2A69E 5TMFE 3S2DF 5C4JF 3S17F 4C3IF 4G7OE 4XLNE 1IW7E 2A6EE 1WCMF 2JA6F 3HOXF 2WAQK 2E2IF 5M5YF 5D4CE 3S15F 5C4XF 2E2JF 1Y1WF 5IYBF 1TWGF 5FJ8F 4A3CF 2R7ZF 3HKZK 4ZH4E 2PPBE 2B63F 5D4EE 2VUMF 3HOYF 4A3MF 3HOUF 4OIOE 4G7HE 4C2MF 3GTJF 4BY1F 4YFNE 5M5WF 5C3EF 2PMZK 3S2HF 2NVYF 3K7AF 4BBRF 3I4MF 5E17E 5IPLE 3M4OF 5FLMF 2JA5F 1TWCF 4YG2E 3GTKF 5IYDF 2WB1I 2NVQF 4OIQE 4AYBK 3M3YF 4MQ9E 1SMYE 5BYHE 3S14F 4A3GF 1TWHF 3H0GF 3S1RF 3HOWF 1TWAF 4LJZE 3HOZF 3WODE 4XSZE 4Y52F 2YU9F 4KN4E 2O5JE 3RZOF 2O5IE 1Y1VF 5C44F 4XLPE 4OIRE 2NVXF 4A3IF 4LK0E 5TMCE
chains in the Genus database with same CATH superfamily
4A3EE 2E2HE 3HOVE 3S1NF 5M3MF 1I6HE 4A3FE 3S16F 3DXJE 4A93E 2E2HF 4YFKE 1I6HF 3HOVF 2Y0SI 4A3FF 1I6VE 2Y0SH 3HKZH 4A93F 4Y7NF 4QIWH 3CQZE 5E18E 2A6HE 4XSXE 2BE5E 3S1QE 2JA7E 3GTLE 5IYCF 3GTQE 2A68E 1QKLA 3CQZF 1HQME 4JK1E 5IP9E 2NVTE 4C3HE 3S1QF 3GTQF 5IP7F 3H3VF 5IP9F 4OIPE 4C3HF 4MEYE 2JA8E 2PMZH 2NVTF 3EQLE 4Q5SE 4GZYE 2R92E 3RZDF 4BBSE 2JA8F 4A3DF 4A3KF 5C4JE 3PO3E 1YNJK 1I50F 2CW0E 3FKIE 4A3LE 1WCME 3PO3F 4BXXF 4G7ZE 3FKIF 5M5XE 2JA6E 3HOXE 4LK1E 4C3JE 2E2IE 4A3LF 3GTGE 2R93E 5M5XF 4C3JF 4A3JE 2R93F 3GTGF 4AYBH 1TWFE 4YFXE 3GTPE 4A3JF 3I4NE 4Q4ZE 3PO2E 1EIKA 1I3QE 5D4DE 4A3EF 5IYBE 1TWFF 1TWGE 3GTPF 3I4NF 3S1ME 3PO2F 1I3QF 4OINE 1K83E 3S1MF 4X6AE 1R9TE 5M3FE 1K83F 1SFOE 4KN7E 4X6AF 1R9TF 3GTME 5M3FF 3GTOE 1SFOF 4A3ME 3HOUE 3H3VG 2JA7F 4LLGE 4MEXE 3GTLF 3GTMF 3GTOF 3GTJE 4A3BE 2NVYE 2KRXA 4A3BF 4A3DE 4BY7E 3S2DE 3M4OE 2R92F 3S17E 4BY7F 5FLME 4BBSF 1ZYRE 4KMUE 1YNNK 2A69E 5TMFE 4C3IE 3S2DF 5C4JF 3S17F 4C3IF 4G7OE 4XLNE 1IW7E 2A6EE 1WCMF 5M5YE 3S15E 2JA6F 5C4XE 3HOXF 2WAQK 2E2IF 5M5YF 5D4CE 3S15F 2E2JE 5C4XF 1Y1WE 2E2JF 4A3CE 5FJ8E 2R7ZE 1Y1WF 3HOWE 5IYBF 1TWGF 5FJ8F 2B63E 4A3CF 2R7ZF 3HKZK 4ZH4E 2PPBE 2VUME 3HOYE 4QIWK 2B63F 5D4EE 2YU9E 2VUMF 3HOYF 4C2ME 5C44E 4BY1E 4A3MF 5M5WE 5C3EE 3HOUF 3S2HE 3K7AE 2NVXE 4BBRE 4G7HE 4C2MF 3GTJF 4BY1F 4YFNE 5M5WF 5C3EF 2PMZK 3S2HF 2NVYF 3K7AF 4BBRF 3I4ME 1DZFA 3I4MF 5E17E 5IPLE 3M4OF 3S1NE 2JA5E 5FLMF 1TWCE 2JA5F 3GTKE 1TWCF 5IYDE 4Y7NE 4YG2E 4OIOE 3GTKF 5IYDF 2NVQE 3M3YE 2WB1I 5IYCE 2WB1H 4OIQE 4AYBK 2NVQF 1TWHE 3M3YF 3H0GE 4MQ9E 1SMYE 5IP7E 4A3GE 5BYHE 3S14F 3S1RE 4A3GF 1TWHF 3H0GF 1TWAE 3HOZE 3S1RF 3HOWF 3RZDE 4A3KE 4Y52E 1TWAF 4LJZE 3HOZF 3WODE 4XSZE 4Y52F 2YU9F 3RZOE 1I50E 1Y1VE 4KN4E 3S14E 3RZOF 4BXXE 2O5JE 4A3IE 1Y1VF 5C44F 4XLPE 2O5IE 4OIRE 2NVXF 4A3IF 2WAQH 4LK0E 5TMCE 5M3ME 3S16E
chains in the Genus database with same CATH topology
3S1NF 5M3MF 3S16F 3DXJE 2E2HF 4YFKE 1I6HF 3HOVF 2Y0SI 4A3FF 1I6VE 4A93F 4Y7NF 5E18E 2A6HE 4XSXE 2BE5E 5IYCF 2A68E 1QKLA 3CQZF 1HQME 4JK1E 3S1QF 3GTQF 5IP7F 5IP9F 4OIPE 4C3HF 4MEYE 2NVTF 3EQLE 4Q5SE 4GZYE 3RZDF 2JA8F 4A3KF 1YNJK 1I50F 2CW0E 3PO3F 4BXXF 4G7ZE 3FKIF 4LK1E 4A3LF 5M5XF 4C3JF 2R93F 3GTGF 4YFXE 4A3JF 4Q4ZE 4A3EF 5D4DE 3I4NF 1TWFF 3GTPF 3PO2F 1I3QF 4OINE 3S1MF 1K83F 4KN7E 4X6AF 1R9TF 5M3FF 1SFOF 3H3VG 2JA7F 4LLGE 4MEXE 3GTLF 3GTMF 3GTOF 2KRXA 4A3BF 2R92F 4BY7F 4BBSF 4A3DF 1ZYRE 4KMUE 1YNNK 2A69E 5TMFE 3S2DF 5C4JF 3S17F 4C3IF 4G7OE 4XLNE 1IW7E 2A6EE 1WCMF 2JA6F 3HOXF 2WAQK 2E2IF 5M5YF 5D4CE 3S15F 5C4XF 2E2JF 1Y1WF 5IYBF 1TWGF 5FJ8F 4A3CF 2R7ZF 3HKZK 4ZH4E 2PPBE 4QIWK 2B63F 5D4EE 2VUMF 3HOYF 4A3MF 3HOUF 4OIOE 4G7HE 4C2MF 3GTJF 4BY1F 4YFNE 5M5WF 5C3EF 2PMZK 3S2HF 2NVYF 3K7AF 4BBRF 3I4MF 5E17E 5IPLE 3M4OF 5FLMF 2JA5F 1TWCF 4YG2E 3GTKF 5IYDF 2WB1I 2NVQF 4OIQE 4AYBK 3M3YF 4MQ9E 1SMYE 5BYHE 3S14F 4A3GF 1TWHF 3H0GF 3S1RF 3HOWF 1TWAF 4LJZE 3HOZF 3WODE 4XSZE 4Y52F 2YU9F 4KN4E 2O5JE 3RZOF 2O5IE 1Y1VF 5C44F 4XLPE 4OIRE 2NVXF 4A3IF 4LK0E 5TMCE
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3S1N F;  5M3M F;  3S16 F;  3DXJ E;  2E2H F;  4YFK E;  1I6H F;  3HOV F;  2Y0S I;  4A3F F;  1I6V E;  4A93 F;  4Y7N F;  5E18 E;  2A6H E;  4XSX E;  2BE5 E;  5IYC F;  2A68 E;  1QKL A;  3CQZ F;  1HQM E;  4JK1 E;  3S1Q F;  3GTQ F;  5IP7 F;  5IP9 F;  4OIP E;  4C3H F;  4MEY E;  2NVT F;  3EQL E;  4Q5S E;  4GZY E;  3RZD F;  2JA8 F;  4A3K F;  1YNJ K;  1I50 F;  2CW0 E;  3PO3 F;  4BXX F;  4G7Z E;  3FKI F;  4LK1 E;  4A3L F;  5M5X F;  4C3J F;  2R93 F;  3GTG F;  4YFX E;  4A3J F;  4Q4Z E;  4A3E F;  5D4D E;  3I4N F;  1TWF F;  3GTP F;  3PO2 F;  1I3Q F;  4OIN E;  3S1M F;  1K83 F;  4KN7 E;  4X6A F;  1R9T F;  5M3F F;  1SFO F;  3H3V G;  2JA7 F;  4LLG E;  4MEX E;  3GTL F;  3GTM F;  3GTO F;  4A3B F;  2R92 F;  4BY7 F;  4BBS F;  4A3D F;  1ZYR E;  4KMU E;  1YNN K;  2A69 E;  5TMF E;  3S2D F;  5C4J F;  3S17 F;  4C3I F;  4G7O E;  4XLN E;  1IW7 E;  2A6E E;  1WCM F;  2JA6 F;  3HOX F;  2WAQ K;  2E2I F;  5M5Y F;  5D4C E;  3S15 F;  5C4X F;  2E2J F;  1Y1W F;  5IYB F;  1TWG F;  5FJ8 F;  4A3C F;  2R7Z F;  3HKZ K;  4ZH4 E;  2PPB E;  2B63 F;  5D4E E;  2VUM F;  3HOY F;  4A3M F;  3HOU F;  4OIO E;  4G7H E;  4C2M F;  3GTJ F;  4BY1 F;  4YFN E;  5M5W F;  5C3E F;  2PMZ K;  3S2H F;  2NVY F;  3K7A F;  4BBR F;  3I4M F;  5E17 E;  5IPL E;  3M4O F;  5FLM F;  2JA5 F;  1TWC F;  4YG2 E;  3GTK F;  5IYD F;  2WB1 I;  2NVQ F;  4OIQ E;  4AYB K;  3M3Y F;  4MQ9 E;  1SMY E;  5BYH E;  3S14 F;  4A3G F;  1TWH F;  3H0G F;  3S1R F;  3HOW F;  1TWA F;  4LJZ E;  3HOZ F;  3WOD E;  4XSZ E;  4Y52 F;  2YU9 F;  4KN4 E;  2O5J E;  3RZO F;  2O5I E;  1Y1V F;  5C44 F;  4XLP E;  4OIR E;  2NVX F;  4A3I F;  4LK0 E;  5TMC E; 
#chains in the Genus database with same CATH topology
 4A3E E;  2E2H E;  3HOV E;  3S1N F;  5M3M F;  1I6H E;  4A3F E;  3S16 F;  3DXJ E;  4A93 E;  2E2H F;  4YFK E;  1I6H F;  3HOV F;  2Y0S I;  4A3F F;  1I6V E;  2Y0S H;  3HKZ H;  4A93 F;  4Y7N F;  4QIW H;  3CQZ E;  5E18 E;  2A6H E;  4XSX E;  2BE5 E;  3S1Q E;  2JA7 E;  3GTL E;  5IYC F;  3GTQ E;  2A68 E;  1QKL A;  3CQZ F;  1HQM E;  4JK1 E;  5IP9 E;  2NVT E;  4C3H E;  3S1Q F;  3GTQ F;  5IP7 F;  3H3V F;  5IP9 F;  4OIP E;  4C3H F;  4MEY E;  2JA8 E;  2PMZ H;  2NVT F;  3EQL E;  4Q5S E;  4GZY E;  2R92 E;  3RZD F;  4BBS E;  2JA8 F;  4A3D F;  4A3K F;  5C4J E;  3PO3 E;  1YNJ K;  1I50 F;  2CW0 E;  3FKI E;  4A3L E;  1WCM E;  3PO3 F;  4BXX F;  4G7Z E;  3FKI F;  5M5X E;  2JA6 E;  3HOX E;  4LK1 E;  4C3J E;  2E2I E;  4A3L F;  3GTG E;  2R93 E;  5M5X F;  4C3J F;  4A3J E;  2R93 F;  3GTG F;  4AYB H;  1TWF E;  4YFX E;  3GTP E;  4A3J F;  3I4N E;  4Q4Z E;  3PO2 E;  1EIK A;  1I3Q E;  5D4D E;  4A3E F;  5IYB E;  1TWF F;  1TWG E;  3GTP F;  3I4N F;  3S1M E;  3PO2 F;  1I3Q F;  4OIN E;  1K83 E;  3S1M F;  4X6A E;  1R9T E;  5M3F E;  1K83 F;  1SFO E;  4KN7 E;  4X6A F;  1R9T F;  3GTM E;  5M3F F;  3GTO E;  1SFO F;  4A3M E;  3HOU E;  3H3V G;  2JA7 F;  4LLG E;  4MEX E;  3GTL F;  3GTM F;  3GTO F;  3GTJ E;  4A3B E;  2NVY E;  2KRX A;  4A3B F;  4A3D E;  4BY7 E;  3S2D E;  3M4O E;  2R92 F;  3S17 E;  4BY7 F;  5FLM E;  4BBS F;  1ZYR E;  4KMU E;  1YNN K;  2A69 E;  5TMF E;  4C3I E;  3S2D F;  5C4J F;  3S17 F;  4C3I F;  4G7O E;  4XLN E;  1IW7 E;  2A6E E;  1WCM F;  5M5Y E;  3S15 E;  2JA6 F;  5C4X E;  3HOX F;  2WAQ K;  2E2I F;  5M5Y F;  5D4C E;  3S15 F;  2E2J E;  5C4X F;  1Y1W E;  2E2J F;  4A3C E;  5FJ8 E;  2R7Z E;  1Y1W F;  3HOW E;  5IYB F;  1TWG F;  5FJ8 F;  2B63 E;  4A3C F;  2R7Z F;  3HKZ K;  4ZH4 E;  2PPB E;  2VUM E;  3HOY E;  4QIW K;  2B63 F;  5D4E E;  2YU9 E;  2VUM F;  3HOY F;  4C2M E;  5C44 E;  4BY1 E;  4A3M F;  5M5W E;  5C3E E;  3HOU F;  3S2H E;  3K7A E;  2NVX E;  4BBR E;  4G7H E;  4C2M F;  3GTJ F;  4BY1 F;  4YFN E;  5M5W F;  5C3E F;  2PMZ K;  3S2H F;  2NVY F;  3K7A F;  4BBR F;  3I4M E;  1DZF A;  3I4M F;  5E17 E;  5IPL E;  3M4O F;  3S1N E;  2JA5 E;  5FLM F;  1TWC E;  2JA5 F;  3GTK E;  1TWC F;  5IYD E;  4Y7N E;  4YG2 E;  4OIO E;  3GTK F;  5IYD F;  2NVQ E;  3M3Y E;  2WB1 I;  5IYC E;  2WB1 H;  4OIQ E;  4AYB K;  2NVQ F;  1TWH E;  3M3Y F;  3H0G E;  4MQ9 E;  1SMY E;  5IP7 E;  4A3G E;  5BYH E;  3S14 F;  3S1R E;  4A3G F;  1TWH F;  3H0G F;  1TWA E;  3HOZ E;  3S1R F;  3HOW F;  3RZD E;  4A3K E;  4Y52 E;  1TWA F;  4LJZ E;  3HOZ F;  3WOD E;  4XSZ E;  4Y52 F;  2YU9 F;  3RZO E;  1I50 E;  1Y1V E;  4KN4 E;  3S14 E;  3RZO F;  4BXX E;  2O5J E;  4A3I E;  1Y1V F;  5C44 F;  4XLP E;  2O5I E;  4OIR E;  2NVX F;  4A3I F;  2WAQ H;  4LK0 E;  5TMC E;  5M3M E;  3S16 E; 
#chains in the Genus database with same CATH homology
 3S1N F;  5M3M F;  3S16 F;  3DXJ E;  2E2H F;  4YFK E;  1I6H F;  3HOV F;  2Y0S I;  4A3F F;  1I6V E;  4A93 F;  4Y7N F;  5E18 E;  2A6H E;  4XSX E;  2BE5 E;  5IYC F;  2A68 E;  1QKL A;  3CQZ F;  1HQM E;  4JK1 E;  3S1Q F;  3GTQ F;  5IP7 F;  5IP9 F;  4OIP E;  4C3H F;  4MEY E;  2NVT F;  3EQL E;  4Q5S E;  4GZY E;  3RZD F;  2JA8 F;  4A3K F;  1YNJ K;  1I50 F;  2CW0 E;  3PO3 F;  4BXX F;  4G7Z E;  3FKI F;  4LK1 E;  4A3L F;  5M5X F;  4C3J F;  2R93 F;  3GTG F;  4YFX E;  4A3J F;  4Q4Z E;  4A3E F;  5D4D E;  3I4N F;  1TWF F;  3GTP F;  3PO2 F;  1I3Q F;  4OIN E;  3S1M F;  1K83 F;  4KN7 E;  4X6A F;  1R9T F;  5M3F F;  1SFO F;  3H3V G;  2JA7 F;  4LLG E;  4MEX E;  3GTL F;  3GTM F;  3GTO F;  2KRX A;  4A3B F;  2R92 F;  4BY7 F;  4BBS F;  4A3D F;  1ZYR E;  4KMU E;  1YNN K;  2A69 E;  5TMF E;  3S2D F;  5C4J F;  3S17 F;  4C3I F;  4G7O E;  4XLN E;  1IW7 E;  2A6E E;  1WCM F;  2JA6 F;  3HOX F;  2WAQ K;  2E2I F;  5M5Y F;  5D4C E;  3S15 F;  5C4X F;  2E2J F;  1Y1W F;  5IYB F;  1TWG F;  5FJ8 F;  4A3C F;  2R7Z F;  3HKZ K;  4ZH4 E;  2PPB E;  4QIW K;  2B63 F;  5D4E E;  2VUM F;  3HOY F;  4A3M F;  3HOU F;  4OIO E;  4G7H E;  4C2M F;  3GTJ F;  4BY1 F;  4YFN E;  5M5W F;  5C3E F;  2PMZ K;  3S2H F;  2NVY F;  3K7A F;  4BBR F;  3I4M F;  5E17 E;  5IPL E;  3M4O F;  5FLM F;  2JA5 F;  1TWC F;  4YG2 E;  3GTK F;  5IYD F;  2WB1 I;  2NVQ F;  4OIQ E;  4AYB K;  3M3Y F;  4MQ9 E;  1SMY E;  5BYH E;  3S14 F;  4A3G F;  1TWH F;  3H0G F;  3S1R F;  3HOW F;  1TWA F;  4LJZ E;  3HOZ F;  3WOD E;  4XSZ E;  4Y52 F;  2YU9 F;  4KN4 E;  2O5J E;  3RZO F;  2O5I E;  1Y1V F;  5C44 F;  4XLP E;  4OIR E;  2NVX F;  4A3I F;  4LK0 E;  5TMC E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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