4XLNE

Crystal structure of t. aquaticus transcription initiation complex containing bubble promoter and rna
Total Genus 20
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
20
sequence length
93
structure length
93
Chain Sequence
AEPGIDKLFGMVDSKYRLTVVVAKRAQQLLRHRFKNTVLEPEERPKMRTLEGLYDDPNAVTWAMKELLTGRLFFGENLVPEDRLQKEMERLYP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of a bacterial RNA polymerase holoenzyme open promoter complex.
pubmed doi rcsb
molecule tags Transcription/dna/rna
source organism Thermus aquaticus
molecule keywords DNA-directed RNA polymerase subunit alpha
total genus 20
structure length 93
sequence length 93
chains with identical sequence K
ec nomenclature ec 2.7.7.6: DNA-directed RNA polymerase.
pdb deposition date 2015-01-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF01192 RNA_pol_Rpb6 RNA polymerase Rpb6
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.940.10 Alpha Beta Alpha-Beta Complex Eukaryotic RPB6 RNA polymerase subunit Eukaryotic RPB6 RNA polymerase subunit 4xlnE00
4YFNE 4Y52F 1Y1WF 3HOVF 4C3HF 5TMCE 1YNJK 1I6VE 4MEYE 5BYHE 5D4CE 2NVQF 2YU9F 4XSXE 2BE5E 4A3DF 4LK1E 1K83F 2NVYF 5IP7F 3S1MF 3EQLE 4Q4ZE 2E2HF 4G7ZE 3GTLF 3GTGF 2E2JF 2JA5F 4KN4E 1ZYRE 3DXJE 4MQ9E 1R9TF 2NVXF 1HQME 1I3QF 3S1NF 4BY1F 3FKIF 4A3CF 3GTKF 5M5XF 2NVTF 5D4DE 4A93F 2Y0SI 1TWGF 5M5YF 1QKLA 2JA7F 3I4MF 3H0GF 4Q5SE 5FLMF 3HOXF 2VUMF 4A3KF 5C3EF 1WCMF 4YFKE 4MEXE 4KN7E 3RZDF 4XSZE 1Y1VF 4AYBK 3M4OF 5E18E 4A3FF 3S16F 2A68E 4Y7NF 1IW7E 4YG2E 4LLGE 3I4NF 5IPLE 4GZYE 1SFOF 1I50F 4X6AF 5C4JF 2R92F 3GTQF 5IYBF 4G7HE 2JA8F 3K7AF 1I6HF 1TWAF 4C3IF 5C4XF 2WAQK 4JK1E 4A3GF 4ZH4E 3GTJF 2PPBE 3S2HF 4BXXF 2R93F 2B63F 3WODE 4XLPE 3HKZK 4A3LF 1YNNK 3S17F 3H3VG 3S14F 3HOYF 3M3YF 2PMZK 4LK0E 4OIRE 2A6EE 5IYDF 5D4EE 4OINE 5E17E 4G7OE 1TWHF 2R7ZF 2WB1I 4OIPE 5C44F 3S15F 5M3MF 1TWFF 3S1RF 4A3JF 3HOUF 4A3BF 5TMFE 3GTMF 1SMYE 2O5JE 4KMUE 2A6HE 4XLNE 3PO3F 4BY7F 5FJ8F 4OIOE 4YFXE 4C3JF 3GTPF 4BBRF 3S1QF 3CQZF 2JA6F 4A3IF 3GTOF 2A69E 3RZOF 4OIQE 5IP9F 3S2DF 5M5WF 3PO2F 2O5IE 5IYCF 4BBSF 2CW0E 3HOWF 4LJZE 4A3MF 1TWCF 5M3FF 4A3EF 4C2MF 2E2IF 3HOZF
chains in the Genus database with same CATH superfamily
4YFNE 4Y52F 3RZDE 1Y1WF 3HOVF 4QIWH 4C3HF 4A3DE 2WAQH 5TMCE 4A3FE 1YNJK 1I6VE 2NVYE 4MEYE 5BYHE 3S1ME 3GTLE 5D4CE 2E2HE 2NVQF 2YU9F 3I4NE 4XSXE 2BE5E 4A3DF 2JA5E 1SFOE 1I50E 4LK1E 1K83F 5C4JE 3GTQE 2NVYF 5IP7F 3S1MF 3EQLE 4Q4ZE 1I3QE 4G7ZE 2E2HF 3GTLF 3K7AE 3GTGF 1EIKA 2E2JF 4BY1E 2JA5F 3FKIE 4KN4E 1ZYRE 3DXJE 4MQ9E 1R9TF 5M5XE 3GTKE 2NVXF 1HQME 2NVTE 1I3QF 4A3GE 3S1NF 4BY1F 4QIWK 5M5YE 3FKIF 3S2HE 2PMZH 4A3CF 3I4ME 3GTKF 5M5XF 4BXXE 2NVTF 2R93E 1DZFA 5D4DE 4A93F 2B63E 2Y0SI 1TWGF 5M5YF 1QKLA 2JA7F 4A3LE 3I4MF 3H0GF 4Q5SE 3H3VF 3S17E 5FLMF 3HOXF 2VUMF 3S14E 1Y1VE 3HOYE 4A3KF 5C3EF 3M3YE 1WCMF 4YFKE 4MEXE 3M4OE 4KN7E 3S16E 4Y7NE 3RZDF 4XSZE 1Y1VF 4AYBK 3M4OF 5IYDE 4X6AE 2R92E 5E18E 4A3FF 5IYBE 3S16F 2R7ZE 2A68E 4Y7NF 1IW7E 4YG2E 4LLGE 2JA8E 3S15E 5M3ME 3I4NF 1I6HE 4GZYE 5IPLE 1SFOF 1TWAE 1I50F 3HKZH 4C3IE 5C4JF 4A3JE 5IYBF 3S1RE 2R92F 4G7HE 3GTQF 3GTME 3HOUE 4A3BE 2JA8F 3K7AF 1I6HF 3GTJE 1TWAF 4C3IF 5C4XF 2WAQK 4JK1E 5FJ8E 2KRXA 4C3JE 4A3GF 4ZH4E 3GTJF 2PPBE 3GTPE 3S2HF 4BBRE 4BXXF 2R93F 3S1QE 2JA6E 2B63F 3WODE 4XLPE 3HKZK 3GTOE 4A3LF 3S2DE 5IP9E 1YNNK 5M5WE 3S17F 3H3VG 3S14F 3HOYF 3M3YF 5IYCE 2PMZK 3HOWE 4LK0E 4OIRE 1TWHE 4A3ME 1TWCE 5M3FE 5C44E 4A3EE 2E2IE 1TWFE 2A6EE 5IYDF 4X6AF 5C4XE 5D4EE 4OINE 5E17E 4G7OE 1TWHF 2R7ZF 2WB1I 4OIPE 5C44F 3S15F 1Y1WE 5M3MF 3HOVE 1TWFF 4C3HE 3S1RF 4A3JF 3PO3E 3HOUF 4A3BF 5TMFE 4BY7E 3GTMF 1SMYE 2NVQE 2O5JE 2YU9E 4KMUE 2A6HE 4XLNE 3PO3F 1K83E 4BY7F 2Y0SH 5IP7E 3CQZE 5FJ8F 4OIOE 4YFXE 4C3JF 3GTGE 2E2JE 4A3IE 3GTPF 4BBRF 1R9TE 3RZOE 3S1QF 3CQZF 2NVXE 2JA6F 3PO2E 3S1NE 4A3IF 4BBSE 3GTOF 4A3CE 2A69E 3RZOF 4OIQE 5IP9F 3S2DF 5M5WF 3PO2F 4A93E 1TWGE 4AYBH 4C2ME 2O5IE 5IYCF 2JA7E 3HOZE 2CW0E 3HOWF 4BBSF 4LJZE 3H0GE 4A3MF 1TWCF 5M3FF 4Y52E 5FLME 3HOXE 4A3EF 4C2MF 2E2IF 2VUME 4A3KE 5C3EE 3HOZF 1WCME 2WB1H
chains in the Genus database with same CATH topology
4YFNE 4Y52F 1Y1WF 3HOVF 4C3HF 5TMCE 1YNJK 1I6VE 4MEYE 5BYHE 5D4CE 2NVQF 2YU9F 4XSXE 2BE5E 4A3DF 4LK1E 1K83F 2NVYF 5IP7F 3S1MF 3EQLE 4Q4ZE 2E2HF 4G7ZE 3GTLF 3GTGF 2E2JF 2JA5F 4KN4E 1ZYRE 3DXJE 4MQ9E 1R9TF 2NVXF 1HQME 1I3QF 3S1NF 4BY1F 4QIWK 3FKIF 4A3CF 3GTKF 5M5XF 2NVTF 5D4DE 4A93F 2Y0SI 1TWGF 5M5YF 1QKLA 2JA7F 3I4MF 3H0GF 4Q5SE 5FLMF 3HOXF 2VUMF 4A3KF 5C3EF 1WCMF 4YFKE 4MEXE 4KN7E 3RZDF 4XSZE 1Y1VF 4AYBK 3M4OF 5E18E 4A3FF 3S16F 2A68E 4Y7NF 1IW7E 4YG2E 4LLGE 3I4NF 5IPLE 4GZYE 1SFOF 1I50F 4X6AF 5C4JF 2R92F 3GTQF 5IYBF 4G7HE 2JA8F 3K7AF 1I6HF 1TWAF 4C3IF 5C4XF 2WAQK 4JK1E 2KRXA 4A3GF 4ZH4E 3GTJF 2PPBE 3S2HF 4BXXF 2R93F 2B63F 3WODE 4XLPE 3HKZK 4A3LF 1YNNK 3S17F 3H3VG 3S14F 3HOYF 3M3YF 2PMZK 4LK0E 4OIRE 2A6EE 5IYDF 5D4EE 4OINE 5E17E 4G7OE 1TWHF 2R7ZF 2WB1I 4OIPE 5C44F 3S15F 5M3MF 1TWFF 3S1RF 4A3JF 3HOUF 4A3BF 5TMFE 3GTMF 1SMYE 2O5JE 4KMUE 2A6HE 4XLNE 3PO3F 4BY7F 5FJ8F 4OIOE 4YFXE 4C3JF 3GTPF 4BBRF 3S1QF 3CQZF 2JA6F 4A3IF 3GTOF 2A69E 3RZOF 4OIQE 5IP9F 3S2DF 5M5WF 3PO2F 2O5IE 5IYCF 4BBSF 2CW0E 3HOWF 4LJZE 4A3MF 1TWCF 5M3FF 4A3EF 4C2MF 2E2IF 3HOZF
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4YFN E;  4Y52 F;  1Y1W F;  3HOV F;  4C3H F;  5TMC E;  1YNJ K;  1I6V E;  4MEY E;  5BYH E;  5D4C E;  2NVQ F;  2YU9 F;  4XSX E;  2BE5 E;  4A3D F;  4LK1 E;  1K83 F;  2NVY F;  5IP7 F;  3S1M F;  3EQL E;  4Q4Z E;  2E2H F;  4G7Z E;  3GTL F;  3GTG F;  2E2J F;  2JA5 F;  4KN4 E;  1ZYR E;  3DXJ E;  4MQ9 E;  1R9T F;  2NVX F;  1HQM E;  1I3Q F;  3S1N F;  4BY1 F;  3FKI F;  4A3C F;  3GTK F;  5M5X F;  2NVT F;  5D4D E;  4A93 F;  2Y0S I;  1TWG F;  5M5Y F;  1QKL A;  2JA7 F;  3I4M F;  3H0G F;  4Q5S E;  5FLM F;  3HOX F;  2VUM F;  4A3K F;  5C3E F;  1WCM F;  4YFK E;  4MEX E;  4KN7 E;  3RZD F;  4XSZ E;  1Y1V F;  4AYB K;  3M4O F;  5E18 E;  4A3F F;  3S16 F;  2A68 E;  4Y7N F;  1IW7 E;  4YG2 E;  4LLG E;  3I4N F;  5IPL E;  4GZY E;  1SFO F;  1I50 F;  4X6A F;  5C4J F;  2R92 F;  3GTQ F;  5IYB F;  4G7H E;  2JA8 F;  3K7A F;  1I6H F;  1TWA F;  4C3I F;  5C4X F;  2WAQ K;  4JK1 E;  4A3G F;  4ZH4 E;  3GTJ F;  2PPB E;  3S2H F;  4BXX F;  2R93 F;  2B63 F;  3WOD E;  4XLP E;  3HKZ K;  4A3L F;  1YNN K;  3S17 F;  3H3V G;  3S14 F;  3HOY F;  3M3Y F;  2PMZ K;  4LK0 E;  4OIR E;  2A6E E;  5IYD F;  5D4E E;  4OIN E;  5E17 E;  4G7O E;  1TWH F;  2R7Z F;  2WB1 I;  4OIP E;  5C44 F;  3S15 F;  5M3M F;  1TWF F;  3S1R F;  4A3J F;  3HOU F;  4A3B F;  5TMF E;  3GTM F;  1SMY E;  2O5J E;  4KMU E;  2A6H E;  4XLN E;  3PO3 F;  4BY7 F;  5FJ8 F;  4OIO E;  4YFX E;  4C3J F;  3GTP F;  4BBR F;  3S1Q F;  3CQZ F;  2JA6 F;  4A3I F;  3GTO F;  2A69 E;  3RZO F;  4OIQ E;  5IP9 F;  3S2D F;  5M5W F;  3PO2 F;  2O5I E;  5IYC F;  4BBS F;  2CW0 E;  3HOW F;  4LJZ E;  4A3M F;  1TWC F;  5M3F F;  4A3E F;  4C2M F;  2E2I F;  3HOZ F; 
#chains in the Genus database with same CATH topology
 4YFN E;  4Y52 F;  3RZD E;  1Y1W F;  3HOV F;  4QIW H;  4C3H F;  4A3D E;  2WAQ H;  5TMC E;  4A3F E;  1YNJ K;  1I6V E;  2NVY E;  4MEY E;  5BYH E;  3S1M E;  3GTL E;  5D4C E;  2E2H E;  2NVQ F;  2YU9 F;  3I4N E;  4XSX E;  2BE5 E;  4A3D F;  2JA5 E;  1SFO E;  1I50 E;  4LK1 E;  1K83 F;  5C4J E;  3GTQ E;  2NVY F;  5IP7 F;  3S1M F;  3EQL E;  4Q4Z E;  1I3Q E;  4G7Z E;  2E2H F;  3GTL F;  3K7A E;  3GTG F;  1EIK A;  2E2J F;  4BY1 E;  2JA5 F;  3FKI E;  4KN4 E;  1ZYR E;  3DXJ E;  4MQ9 E;  1R9T F;  5M5X E;  3GTK E;  2NVX F;  1HQM E;  2NVT E;  1I3Q F;  4A3G E;  3S1N F;  4BY1 F;  4QIW K;  5M5Y E;  3FKI F;  3S2H E;  2PMZ H;  4A3C F;  3I4M E;  3GTK F;  5M5X F;  4BXX E;  2NVT F;  2R93 E;  1DZF A;  5D4D E;  4A93 F;  2B63 E;  2Y0S I;  1TWG F;  5M5Y F;  1QKL A;  2JA7 F;  4A3L E;  3I4M F;  3H0G F;  4Q5S E;  3H3V F;  3S17 E;  5FLM F;  3HOX F;  2VUM F;  3S14 E;  1Y1V E;  3HOY E;  4A3K F;  5C3E F;  3M3Y E;  1WCM F;  4YFK E;  4MEX E;  3M4O E;  4KN7 E;  3S16 E;  4Y7N E;  3RZD F;  4XSZ E;  1Y1V F;  4AYB K;  3M4O F;  5IYD E;  4X6A E;  2R92 E;  5E18 E;  4A3F F;  5IYB E;  3S16 F;  2R7Z E;  2A68 E;  4Y7N F;  1IW7 E;  4YG2 E;  4LLG E;  2JA8 E;  3S15 E;  5M3M E;  3I4N F;  1I6H E;  4GZY E;  5IPL E;  1SFO F;  1TWA E;  1I50 F;  3HKZ H;  4C3I E;  5C4J F;  4A3J E;  5IYB F;  3S1R E;  2R92 F;  4G7H E;  3GTQ F;  3GTM E;  3HOU E;  4A3B E;  2JA8 F;  3K7A F;  1I6H F;  3GTJ E;  1TWA F;  4C3I F;  5C4X F;  2WAQ K;  4JK1 E;  5FJ8 E;  2KRX A;  4C3J E;  4A3G F;  4ZH4 E;  3GTJ F;  2PPB E;  3GTP E;  3S2H F;  4BBR E;  4BXX F;  2R93 F;  3S1Q E;  2JA6 E;  2B63 F;  3WOD E;  4XLP E;  3HKZ K;  3GTO E;  4A3L F;  3S2D E;  5IP9 E;  1YNN K;  5M5W E;  3S17 F;  3H3V G;  3S14 F;  3HOY F;  3M3Y F;  5IYC E;  2PMZ K;  3HOW E;  4LK0 E;  4OIR E;  1TWH E;  4A3M E;  1TWC E;  5M3F E;  5C44 E;  4A3E E;  2E2I E;  1TWF E;  2A6E E;  5IYD F;  4X6A F;  5C4X E;  5D4E E;  4OIN E;  5E17 E;  4G7O E;  1TWH F;  2R7Z F;  2WB1 I;  4OIP E;  5C44 F;  3S15 F;  1Y1W E;  5M3M F;  3HOV E;  1TWF F;  4C3H E;  3S1R F;  4A3J F;  3PO3 E;  3HOU F;  4A3B F;  5TMF E;  4BY7 E;  3GTM F;  1SMY E;  2NVQ E;  2O5J E;  2YU9 E;  4KMU E;  2A6H E;  4XLN E;  3PO3 F;  1K83 E;  4BY7 F;  2Y0S H;  5IP7 E;  3CQZ E;  5FJ8 F;  4OIO E;  4YFX E;  4C3J F;  3GTG E;  2E2J E;  4A3I E;  3GTP F;  4BBR F;  1R9T E;  3RZO E;  3S1Q F;  3CQZ F;  2NVX E;  2JA6 F;  3PO2 E;  3S1N E;  4A3I F;  4BBS E;  3GTO F;  4A3C E;  2A69 E;  3RZO F;  4OIQ E;  5IP9 F;  3S2D F;  5M5W F;  3PO2 F;  4A93 E;  1TWG E;  4AYB H;  4C2M E;  2O5I E;  5IYC F;  2JA7 E;  3HOZ E;  2CW0 E;  3HOW F;  4BBS F;  4LJZ E;  3H0G E;  4A3M F;  1TWC F;  5M3F F;  4Y52 E;  5FLM E;  3HOX E;  4A3E F;  4C2M F;  2E2I F;  2VUM E;  4A3K E;  5C3E E;  3HOZ F;  1WCM E;  2WB1 H; 
#chains in the Genus database with same CATH homology
 4YFN E;  4Y52 F;  1Y1W F;  3HOV F;  4C3H F;  5TMC E;  1YNJ K;  1I6V E;  4MEY E;  5BYH E;  5D4C E;  2NVQ F;  2YU9 F;  4XSX E;  2BE5 E;  4A3D F;  4LK1 E;  1K83 F;  2NVY F;  5IP7 F;  3S1M F;  3EQL E;  4Q4Z E;  2E2H F;  4G7Z E;  3GTL F;  3GTG F;  2E2J F;  2JA5 F;  4KN4 E;  1ZYR E;  3DXJ E;  4MQ9 E;  1R9T F;  2NVX F;  1HQM E;  1I3Q F;  3S1N F;  4BY1 F;  4QIW K;  3FKI F;  4A3C F;  3GTK F;  5M5X F;  2NVT F;  5D4D E;  4A93 F;  2Y0S I;  1TWG F;  5M5Y F;  1QKL A;  2JA7 F;  3I4M F;  3H0G F;  4Q5S E;  5FLM F;  3HOX F;  2VUM F;  4A3K F;  5C3E F;  1WCM F;  4YFK E;  4MEX E;  4KN7 E;  3RZD F;  4XSZ E;  1Y1V F;  4AYB K;  3M4O F;  5E18 E;  4A3F F;  3S16 F;  2A68 E;  4Y7N F;  1IW7 E;  4YG2 E;  4LLG E;  3I4N F;  5IPL E;  4GZY E;  1SFO F;  1I50 F;  4X6A F;  5C4J F;  2R92 F;  3GTQ F;  5IYB F;  4G7H E;  2JA8 F;  3K7A F;  1I6H F;  1TWA F;  4C3I F;  5C4X F;  2WAQ K;  4JK1 E;  2KRX A;  4A3G F;  4ZH4 E;  3GTJ F;  2PPB E;  3S2H F;  4BXX F;  2R93 F;  2B63 F;  3WOD E;  4XLP E;  3HKZ K;  4A3L F;  1YNN K;  3S17 F;  3H3V G;  3S14 F;  3HOY F;  3M3Y F;  2PMZ K;  4LK0 E;  4OIR E;  2A6E E;  5IYD F;  5D4E E;  4OIN E;  5E17 E;  4G7O E;  1TWH F;  2R7Z F;  2WB1 I;  4OIP E;  5C44 F;  3S15 F;  5M3M F;  1TWF F;  3S1R F;  4A3J F;  3HOU F;  4A3B F;  5TMF E;  3GTM F;  1SMY E;  2O5J E;  4KMU E;  2A6H E;  4XLN E;  3PO3 F;  4BY7 F;  5FJ8 F;  4OIO E;  4YFX E;  4C3J F;  3GTP F;  4BBR F;  3S1Q F;  3CQZ F;  2JA6 F;  4A3I F;  3GTO F;  2A69 E;  3RZO F;  4OIQ E;  5IP9 F;  3S2D F;  5M5W F;  3PO2 F;  2O5I E;  5IYC F;  4BBS F;  2CW0 E;  3HOW F;  4LJZ E;  4A3M F;  1TWC F;  5M3F F;  4A3E F;  4C2M F;  2E2I F;  3HOZ F; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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