4XLPE

Crystal structure of t.aquaticus transcription initiation complex containing upstream fork promoter
Total Genus 18
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
18
sequence length
93
structure length
93
Chain Sequence
AEPGIDKLFGMVDSKYRLTVVVAKRAQQLLRHRFKNTVLEPEERPKMRTLEGLYDDPNAVTWAMKELLTGRLFFGENLVPEDRLQKEMERLYP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of a bacterial RNA polymerase holoenzyme open promoter complex.
pubmed doi rcsb
molecule tags Transcription/dna
source organism Thermus aquaticus
molecule keywords DNA-directed RNA polymerase subunit alpha
total genus 18
structure length 93
sequence length 93
chains with identical sequence K
ec nomenclature ec 2.7.7.6: DNA-directed RNA polymerase.
pdb deposition date 2015-01-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF01192 RNA_pol_Rpb6 RNA polymerase Rpb6
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.940.10 Alpha Beta Alpha-Beta Complex Eukaryotic RPB6 RNA polymerase subunit Eukaryotic RPB6 RNA polymerase subunit 4xlpE00
2WAQK 1SMYE 3WODE 4YFKE 5FLMF 4A3DF 2VUMF 4KMUE 5E18E 2NVXF 4OIOE 3S1MF 4Y7NF 4XSZE 2R92F 5IYBF 2CW0E 3RZOF 4LK0E 1TWHF 4C3HF 2Y0SI 3I4NF 1I6VE 5E17E 2JA7F 2NVYF 1IW7E 4OIPE 2A69E 4BBSF 5D4DE 5FJ8F 4LK1E 4MQ9E 5D4EE 2A6HE 3S1QF 4YFXE 4KN7E 4G7ZE 4XLPE 4BXXF 5IYCF 1Y1WF 4AYBK 2BE5E 5C3EF 3GTPF 4A3FF 3HOVF 5TMFE 3S16F 4XSXE 2E2JF 3S1NF 5D4CE 3I4MF 3S17F 1K83F 1YNJK 4C3IF 1I3QF 3M3YF 4X6AF 3GTMF 4A3BF 3PO2F 5C4XF 4Q4ZE 4XLNE 1QKLA 2A68E 2WB1I 2JA6F 4BBRF 3S2DF 1TWAF 5M3MF 2PMZK 4KN4E 5M5XF 5BYHE 4A3CF 4Y52F 3RZDF 1YNNK 3GTQF 1WCMF 4A3JF 4OINE 4OIQE 1Y1VF 1R9TF 3HOWF 2JA8F 1I50F 5M5WF 2E2HF 4JK1E 5IPLE 5IP9F 4A3LF 3GTOF 2NVQF 1I6HF 3M4OF 5IYDF 3S15F 3S14F 2A6EE 4A93F 5M3FF 2R7ZF 3H0GF 1ZYRE 3S2HF 3K7AF 4A3GF 4A3KF 1SFOF 3HOYF 5C44F 3GTKF 3GTJF 2B63F 2O5IE 3S1RF 2YU9F 2E2IF 5C4JF 2NVTF 4OIRE 3H3VG 1HQME 5TMCE 4BY1F 5IP7F 4A3MF 3PO3F 4A3IF 4Q5SE 5M5YF 4GZYE 1TWFF 2O5JE 4LLGE 1TWGF 4YFNE 4A3EF 3HOZF 4C2MF 4LJZE 1TWCF 3DXJE 4G7HE 4MEYE 3HOXF 2PPBE 3HKZK 4BY7F 4C3JF 3GTLF 2R93F 4YG2E 3EQLE 3FKIF 3HOUF 4MEXE 2JA5F 4G7OE 3CQZF 3GTGF 4ZH4E
chains in the Genus database with same CATH superfamily
2WAQK 1SMYE 3WODE 4YFKE 5FLMF 3K7AE 3HOXE 3S2HE 4A3DF 1SFOE 2VUMF 4KMUE 3HOYE 5C44E 5E18E 3GTKE 3GTJE 2NVXF 2B63E 4OIOE 3S1MF 4Y7NF 4XSZE 3S1RE 2R92F 5IYBF 2YU9E 2CW0E 5C4JE 2NVTE 3RZOF 4LK0E 1TWHF 4C3HF 4BY1E 2Y0SI 3I4NF 1I6VE 5IP7E 4A3ME 2JA7F 5E17E 2NVYF 1IW7E 4A3IE 4OIPE 2A69E 4BBSF 5D4DE 5FJ8F 2R92E 4LK1E 4MQ9E 5D4EE 2A6HE 3HKZH 3S1QF 4YFXE 4A3EE 4KN7E 3HOZE 4G7ZE 4XLPE 1DZFA 4C2ME 5IYCF 5M3FE 4BXXF 1Y1WF 1TWCE 4AYBK 2BE5E 5C3EF 3GTPF 4A3FF 3HOVF 5TMFE 3S16F 4XSXE 2E2JF 3S1NF 4QIWK 5D4CE 3I4MF 4C3JE 4BY7E 3S17F 1K83F 1YNJK 4C3IF 1I3QF 3GTLE 3M3YF 2WAQH 3GTMF 4A3BF 2R93E 4X6AF 3PO2F 5C4XF 4Q4ZE 4XLNE 1QKLA 2A68E 3FKIE 2WB1I 2JA6F 3HOUE 4BBRF 3S2DF 2JA5E 1TWAF 5M3MF 2PMZK 5C4XE 3CQZE 3GTGE 1Y1VE 4KN4E 5M5XF 5FLME 5BYHE 4A3DE 4Y52F 4A3CF 2VUME 3RZDF 2NVXE 1YNNK 3GTQF 1WCMF 4A3JF 3S1ME 4Y7NE 4A3BE 4OINE 5IYBE 4OIQE 1R9TF 3RZOE 3HOWF 4C3HE 1TWHE 3I4NE 2JA7E 2JA8F 3I4ME 3H3VF 2NVYE 1I50F 5M5WF 2E2HF 4JK1E 5IPLE 5IP9F 4A3LF 3GTOF 2NVQF 1I6HF 3M4OF 5FJ8E 1WCME 4BBSE 1EIKA 4AYBH 5IYDF 3S15F 2Y0SH 4QIWH 3S14F 2A6EE 4A93F 3S1QE 5M3FF 2R7ZF 3H0GF 1ZYRE 4G7OE 3S2HF 3K7AF 5IYCE 4BXXE 4A3GF 4A3KF 1I50E 1Y1WE 1SFOF 3HOYF 5C44F 5C3EE 3GTJF 2B63F 2O5IE 3GTKF 4A3FE 3HOVE 3GTPE 3S16E 3S1RF 2E2JE 2YU9F 2R7ZE 3S1NE 2NVQE 2E2IF 5C4JF 2NVTF 4OIRE 3H3VG 3S17E 2PMZH 1K83E 1HQME 5TMCE 1I3QE 4BY1F 5IYDE 4C3IE 3GTME 3M3YE 4X6AE 5IP7F 4A3MF 3PO3F 3PO2E 3H0GE 2JA6E 4A3IF 4BBRE 4Q5SE 4A3GE 4A3KE 5M5YF 3S2DE 1TWAE 5M3ME 4GZYE 5M5XE 1TWFF 2O5JE 4A3CE 4Y52E 2KRXA 2E2IE 3RZDE 4LLGE 1TWGF 3GTQE 4A3JE 4YFNE 4A3EF 2WB1H 3HOZF 3PO3E 4C2MF 1R9TE 3HOWE 4LJZE 1TWCF 3DXJE 4G7HE 2JA8E 4MEYE 5M5YE 3HOXF 2E2HE 3HKZK 4BY7F 4C3JF 5M5WE 2PPBE 1TWFE 3GTLF 2R93F 5IP9E 4A3LE 3GTOE 1TWGE 4YG2E 3M4OE 1I6HE 4ZH4E 3EQLE 3FKIF 3HOUF 3S15E 4MEXE 2JA5F 3S14E 4A93E 3CQZF 3GTGF 1Y1VF
chains in the Genus database with same CATH topology
2WAQK 1SMYE 3WODE 4YFKE 5FLMF 4A3DF 2VUMF 4KMUE 5E18E 2NVXF 4OIOE 3S1MF 4Y7NF 4XSZE 2R92F 5IYBF 2CW0E 3RZOF 4LK0E 1TWHF 4C3HF 2Y0SI 3I4NF 1I6VE 5E17E 2JA7F 2NVYF 1IW7E 4OIPE 2A69E 4BBSF 5D4DE 5FJ8F 4LK1E 4MQ9E 5D4EE 2A6HE 3S1QF 4YFXE 4KN7E 4G7ZE 4XLPE 4BXXF 5IYCF 1Y1WF 4AYBK 2BE5E 5C3EF 3GTPF 4A3FF 3HOVF 5TMFE 3S16F 4XSXE 2E2JF 3S1NF 4QIWK 5D4CE 3I4MF 3S17F 1K83F 1YNJK 4C3IF 1I3QF 3M3YF 4X6AF 3GTMF 4A3BF 3PO2F 5C4XF 4Q4ZE 4XLNE 1QKLA 2A68E 2WB1I 2JA6F 4BBRF 3S2DF 1TWAF 5M3MF 2PMZK 4KN4E 5M5XF 5BYHE 4A3CF 4Y52F 3RZDF 1YNNK 3GTQF 1WCMF 4A3JF 4OINE 4OIQE 1Y1VF 1R9TF 3HOWF 2JA8F 1I50F 5M5WF 2E2HF 4JK1E 5IPLE 5IP9F 4A3LF 3GTOF 2NVQF 1I6HF 3M4OF 5IYDF 3S15F 3S14F 2A6EE 4A93F 5M3FF 2R7ZF 3H0GF 1ZYRE 3S2HF 3K7AF 4A3GF 4A3KF 1SFOF 3HOYF 5C44F 3GTKF 3GTJF 2B63F 2O5IE 3S1RF 2YU9F 2E2IF 5C4JF 2NVTF 4OIRE 3H3VG 1HQME 5TMCE 4BY1F 5IP7F 4A3MF 3PO3F 4A3IF 4Q5SE 5M5YF 4GZYE 1TWFF 2O5JE 2KRXA 4LLGE 1TWGF 4YFNE 4A3EF 3HOZF 4C2MF 4LJZE 1TWCF 3DXJE 4G7HE 4MEYE 3HOXF 2PPBE 3HKZK 4BY7F 4C3JF 3GTLF 2R93F 4YG2E 3EQLE 3FKIF 3HOUF 4MEXE 2JA5F 4G7OE 3CQZF 3GTGF 4ZH4E
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2WAQ K;  1SMY E;  3WOD E;  4YFK E;  5FLM F;  4A3D F;  2VUM F;  4KMU E;  5E18 E;  2NVX F;  4OIO E;  3S1M F;  4Y7N F;  4XSZ E;  2R92 F;  5IYB F;  2CW0 E;  3RZO F;  4LK0 E;  1TWH F;  4C3H F;  2Y0S I;  3I4N F;  1I6V E;  5E17 E;  2JA7 F;  2NVY F;  1IW7 E;  4OIP E;  2A69 E;  4BBS F;  5D4D E;  5FJ8 F;  4LK1 E;  4MQ9 E;  5D4E E;  2A6H E;  3S1Q F;  4YFX E;  4KN7 E;  4G7Z E;  4XLP E;  4BXX F;  5IYC F;  1Y1W F;  4AYB K;  2BE5 E;  5C3E F;  3GTP F;  4A3F F;  3HOV F;  5TMF E;  3S16 F;  4XSX E;  2E2J F;  3S1N F;  5D4C E;  3I4M F;  3S17 F;  1K83 F;  1YNJ K;  4C3I F;  1I3Q F;  3M3Y F;  4X6A F;  3GTM F;  4A3B F;  3PO2 F;  5C4X F;  4Q4Z E;  4XLN E;  1QKL A;  2A68 E;  2WB1 I;  2JA6 F;  4BBR F;  3S2D F;  1TWA F;  5M3M F;  2PMZ K;  4KN4 E;  5M5X F;  5BYH E;  4A3C F;  4Y52 F;  3RZD F;  1YNN K;  3GTQ F;  1WCM F;  4A3J F;  4OIN E;  4OIQ E;  1Y1V F;  1R9T F;  3HOW F;  2JA8 F;  1I50 F;  5M5W F;  2E2H F;  4JK1 E;  5IPL E;  5IP9 F;  4A3L F;  3GTO F;  2NVQ F;  1I6H F;  3M4O F;  5IYD F;  3S15 F;  3S14 F;  2A6E E;  4A93 F;  5M3F F;  2R7Z F;  3H0G F;  1ZYR E;  3S2H F;  3K7A F;  4A3G F;  4A3K F;  1SFO F;  3HOY F;  5C44 F;  3GTK F;  3GTJ F;  2B63 F;  2O5I E;  3S1R F;  2YU9 F;  2E2I F;  5C4J F;  2NVT F;  4OIR E;  3H3V G;  1HQM E;  5TMC E;  4BY1 F;  5IP7 F;  4A3M F;  3PO3 F;  4A3I F;  4Q5S E;  5M5Y F;  4GZY E;  1TWF F;  2O5J E;  4LLG E;  1TWG F;  4YFN E;  4A3E F;  3HOZ F;  4C2M F;  4LJZ E;  1TWC F;  3DXJ E;  4G7H E;  4MEY E;  3HOX F;  2PPB E;  3HKZ K;  4BY7 F;  4C3J F;  3GTL F;  2R93 F;  4YG2 E;  3EQL E;  3FKI F;  3HOU F;  4MEX E;  2JA5 F;  4G7O E;  3CQZ F;  3GTG F;  4ZH4 E; 
#chains in the Genus database with same CATH topology
 2WAQ K;  1SMY E;  3WOD E;  4YFK E;  5FLM F;  3K7A E;  3HOX E;  3S2H E;  4A3D F;  1SFO E;  2VUM F;  4KMU E;  3HOY E;  5C44 E;  5E18 E;  3GTK E;  3GTJ E;  2NVX F;  2B63 E;  4OIO E;  3S1M F;  4Y7N F;  4XSZ E;  3S1R E;  2R92 F;  5IYB F;  2YU9 E;  2CW0 E;  5C4J E;  2NVT E;  3RZO F;  4LK0 E;  1TWH F;  4C3H F;  4BY1 E;  2Y0S I;  3I4N F;  1I6V E;  5IP7 E;  4A3M E;  2JA7 F;  5E17 E;  2NVY F;  1IW7 E;  4A3I E;  4OIP E;  2A69 E;  4BBS F;  5D4D E;  5FJ8 F;  2R92 E;  4LK1 E;  4MQ9 E;  5D4E E;  2A6H E;  3HKZ H;  3S1Q F;  4YFX E;  4A3E E;  4KN7 E;  3HOZ E;  4G7Z E;  4XLP E;  1DZF A;  4C2M E;  5IYC F;  5M3F E;  4BXX F;  1Y1W F;  1TWC E;  4AYB K;  2BE5 E;  5C3E F;  3GTP F;  4A3F F;  3HOV F;  5TMF E;  3S16 F;  4XSX E;  2E2J F;  3S1N F;  4QIW K;  5D4C E;  3I4M F;  4C3J E;  4BY7 E;  3S17 F;  1K83 F;  1YNJ K;  4C3I F;  1I3Q F;  3GTL E;  3M3Y F;  2WAQ H;  3GTM F;  4A3B F;  2R93 E;  4X6A F;  3PO2 F;  5C4X F;  4Q4Z E;  4XLN E;  1QKL A;  2A68 E;  3FKI E;  2WB1 I;  2JA6 F;  3HOU E;  4BBR F;  3S2D F;  2JA5 E;  1TWA F;  5M3M F;  2PMZ K;  5C4X E;  3CQZ E;  3GTG E;  1Y1V E;  4KN4 E;  5M5X F;  5FLM E;  5BYH E;  4A3D E;  4Y52 F;  4A3C F;  2VUM E;  3RZD F;  2NVX E;  1YNN K;  3GTQ F;  1WCM F;  4A3J F;  3S1M E;  4Y7N E;  4A3B E;  4OIN E;  5IYB E;  4OIQ E;  1R9T F;  3RZO E;  3HOW F;  4C3H E;  1TWH E;  3I4N E;  2JA7 E;  2JA8 F;  3I4M E;  3H3V F;  2NVY E;  1I50 F;  5M5W F;  2E2H F;  4JK1 E;  5IPL E;  5IP9 F;  4A3L F;  3GTO F;  2NVQ F;  1I6H F;  3M4O F;  5FJ8 E;  1WCM E;  4BBS E;  1EIK A;  4AYB H;  5IYD F;  3S15 F;  2Y0S H;  4QIW H;  3S14 F;  2A6E E;  4A93 F;  3S1Q E;  5M3F F;  2R7Z F;  3H0G F;  1ZYR E;  4G7O E;  3S2H F;  3K7A F;  5IYC E;  4BXX E;  4A3G F;  4A3K F;  1I50 E;  1Y1W E;  1SFO F;  3HOY F;  5C44 F;  5C3E E;  3GTJ F;  2B63 F;  2O5I E;  3GTK F;  4A3F E;  3HOV E;  3GTP E;  3S16 E;  3S1R F;  2E2J E;  2YU9 F;  2R7Z E;  3S1N E;  2NVQ E;  2E2I F;  5C4J F;  2NVT F;  4OIR E;  3H3V G;  3S17 E;  2PMZ H;  1K83 E;  1HQM E;  5TMC E;  1I3Q E;  4BY1 F;  5IYD E;  4C3I E;  3GTM E;  3M3Y E;  4X6A E;  5IP7 F;  4A3M F;  3PO3 F;  3PO2 E;  3H0G E;  2JA6 E;  4A3I F;  4BBR E;  4Q5S E;  4A3G E;  4A3K E;  5M5Y F;  3S2D E;  1TWA E;  5M3M E;  4GZY E;  5M5X E;  1TWF F;  2O5J E;  4A3C E;  4Y52 E;  2KRX A;  2E2I E;  3RZD E;  4LLG E;  1TWG F;  3GTQ E;  4A3J E;  4YFN E;  4A3E F;  2WB1 H;  3HOZ F;  3PO3 E;  4C2M F;  1R9T E;  3HOW E;  4LJZ E;  1TWC F;  3DXJ E;  4G7H E;  2JA8 E;  4MEY E;  5M5Y E;  3HOX F;  2E2H E;  3HKZ K;  4BY7 F;  4C3J F;  5M5W E;  2PPB E;  1TWF E;  3GTL F;  2R93 F;  5IP9 E;  4A3L E;  3GTO E;  1TWG E;  4YG2 E;  3M4O E;  1I6H E;  4ZH4 E;  3EQL E;  3FKI F;  3HOU F;  3S15 E;  4MEX E;  2JA5 F;  3S14 E;  4A93 E;  3CQZ F;  3GTG F;  1Y1V F; 
#chains in the Genus database with same CATH homology
 2WAQ K;  1SMY E;  3WOD E;  4YFK E;  5FLM F;  4A3D F;  2VUM F;  4KMU E;  5E18 E;  2NVX F;  4OIO E;  3S1M F;  4Y7N F;  4XSZ E;  2R92 F;  5IYB F;  2CW0 E;  3RZO F;  4LK0 E;  1TWH F;  4C3H F;  2Y0S I;  3I4N F;  1I6V E;  5E17 E;  2JA7 F;  2NVY F;  1IW7 E;  4OIP E;  2A69 E;  4BBS F;  5D4D E;  5FJ8 F;  4LK1 E;  4MQ9 E;  5D4E E;  2A6H E;  3S1Q F;  4YFX E;  4KN7 E;  4G7Z E;  4XLP E;  4BXX F;  5IYC F;  1Y1W F;  4AYB K;  2BE5 E;  5C3E F;  3GTP F;  4A3F F;  3HOV F;  5TMF E;  3S16 F;  4XSX E;  2E2J F;  3S1N F;  4QIW K;  5D4C E;  3I4M F;  3S17 F;  1K83 F;  1YNJ K;  4C3I F;  1I3Q F;  3M3Y F;  4X6A F;  3GTM F;  4A3B F;  3PO2 F;  5C4X F;  4Q4Z E;  4XLN E;  1QKL A;  2A68 E;  2WB1 I;  2JA6 F;  4BBR F;  3S2D F;  1TWA F;  5M3M F;  2PMZ K;  4KN4 E;  5M5X F;  5BYH E;  4A3C F;  4Y52 F;  3RZD F;  1YNN K;  3GTQ F;  1WCM F;  4A3J F;  4OIN E;  4OIQ E;  1Y1V F;  1R9T F;  3HOW F;  2JA8 F;  1I50 F;  5M5W F;  2E2H F;  4JK1 E;  5IPL E;  5IP9 F;  4A3L F;  3GTO F;  2NVQ F;  1I6H F;  3M4O F;  5IYD F;  3S15 F;  3S14 F;  2A6E E;  4A93 F;  5M3F F;  2R7Z F;  3H0G F;  1ZYR E;  3S2H F;  3K7A F;  4A3G F;  4A3K F;  1SFO F;  3HOY F;  5C44 F;  3GTK F;  3GTJ F;  2B63 F;  2O5I E;  3S1R F;  2YU9 F;  2E2I F;  5C4J F;  2NVT F;  4OIR E;  3H3V G;  1HQM E;  5TMC E;  4BY1 F;  5IP7 F;  4A3M F;  3PO3 F;  4A3I F;  4Q5S E;  5M5Y F;  4GZY E;  1TWF F;  2O5J E;  2KRX A;  4LLG E;  1TWG F;  4YFN E;  4A3E F;  3HOZ F;  4C2M F;  4LJZ E;  1TWC F;  3DXJ E;  4G7H E;  4MEY E;  3HOX F;  2PPB E;  3HKZ K;  4BY7 F;  4C3J F;  3GTL F;  2R93 F;  4YG2 E;  3EQL E;  3FKI F;  3HOU F;  4MEX E;  2JA5 F;  4G7O E;  3CQZ F;  3GTG F;  4ZH4 E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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