4Y52E

Crystal structure of 5-carboxycytosine recognition by rna polymerase ii during transcription elongation.
Total Genus 51
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
51
sequence length
214
structure length
214
Chain Sequence
DQENERNISRLWRAFRTVKEMVKDRGYFITQEEVELPLEDFKAKYCDSMGRPQRKMMSFQANPTEESISKFPDMGSLWVEFCDEPSVGVKTMKTFVIHIQEKNFQTGIFVYQNNITPSAMKLVPSIPPATIETFNEAALVVNITHHELVPKHIRLSSDEKRELLKRYRLKESQLPRIQRADPVALYLGLKRGEVVKIIRKSETSGRYASYRICM
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Molecular basis for 5-carboxycytosine recognition by RNA polymerase II elongation complex.
pubmed doi rcsb
molecule tags Transcription/dna/rna
molecule keywords DNA-directed RNA polymerase II subunit RPB1
total genus 51
structure length 214
sequence length 214
ec nomenclature
pdb deposition date 2015-02-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF01191 RNA_pol_Rpb5_C RNA polymerase Rpb5, C-terminal domain
E PF03871 RNA_pol_Rpb5_N RNA polymerase Rpb5, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1340.10 Alpha Beta 3-Layer(aba) Sandwich Dna-directed Rna Polymerases I, Ii, And Iii 27 Kd Polypeptide; Chain: A; domain 1 RNA polymerase, Rpb5, N-terminal domain 4y52E01
3.90.940.20 Alpha Beta Alpha-Beta Complex Eukaryotic RPB6 RNA polymerase subunit RPB5-like RNA polymerase subunit 4y52E02
2R7ZE 4QIWH 3GTKE 3FKIE 4A3ME 4AYBH 1TWGE 3GTGE 5FJ8E 5IYBE 2JA6E 1TWCE 2WAQH 4A3KE 1TWFE 3S15E 3M3YE 3PO3E 5M3ME 3HOYE 1DZFA 1I50E 1Y1VE 3H0GE 5M5WE 1I6HE 4A3JE 1R9TE 2Y0SH 4C3IE 2NVXE 3S2DE 3RZOE 3GTME 2E2JE 3M4OE 4BBRE 3GTLE 2NVQE 1TWHE 5IYCE 4A3EE 2WB1H 3GTPE 2JA8E 4C3JE 2B63E 2E2IE 5FLME 3S16E 1K83E 4Y52E 1EIKA 4C2ME 5C4XE 2NVTE 5M5XE 4A3GE 3RZDE 4C3HE 1SFOE 3S14E 5IP9E 3HOUE 3GTJE 5C4JE 4A93E 2R92E 2VUME 4A3DE 4X6AE 1TWAE 5C44E 4A3BE 2JA7E 4A3IE 5M5YE 3PO2E 3S1ME 4BY1E 4BY7E 5C3EE 3S17E 3HOXE 4A3FE 3HOVE 3S1NE 3GTOE 3S2HE 3S1RE 4A3CE 1I3QE 4BBSE 4BXXE 1WCME 1Y1WE 3S1QE 2PMZH 3HOZE 5M3FE 3H3VF 3K7AE 3HKZH 3HOWE 2JA5E 2E2HE 3GTQE 5IP7E 3CQZE 4Y7NE 5IYDE 2NVYE 2YU9E 3I4NE 2R93E 4A3LE 3I4ME
chains in the Genus database with same CATH superfamily
2NVYF 2R7ZE 4QIWH 2YU9F 3GTKE 3I4NF 3FKIE 4ZH4E 2R93F 4A3ME 4AYBH 4LLGE 2BE5E 1TWGE 3I4MF 2WB1I 2R7ZF 3GTGE 5FJ8E 3GTKF 5IYBE 3FKIF 2JA6E 2KRXA 1TWCE 2WAQH 4A3MF 4A3KE 1TWGF 2CW0E 4XLNE 1TWFE 3GTGF 3S15E 5FJ8F 5IYBF 4G7ZE 3M3YE 2JA6F 5D4DE 1Y1WF 4BXXF 4A3KF 3PO3E 5M3ME 3HOYE 1DZFA 1TWFF 1I50E 1Y1VE 3H0GE 3M3YF 5M5WE 4LJZE 1I6HE 4A3JE 3PO3F 2O5JE 5M3MF 3HOYF 1R9TE 2Y0SH 5E18E 4C3IE 2NVXE 3S2DE 1Y1VF 3RZOE 3EQLE 3GTME 3H0GF 5TMFE 4Q4ZE 1I6VE 5M5WF 1I6HF 4XSXE 2PPBE 1ZYRE 1R9TF 2E2JE 3H3VG 4YG2E 4YFKE 2PMZK 4C3IF 2NVXF 3M4OE 3S2DF 4BBRE 3RZOF 3GTMF 3GTLE 2NVQE 4A3LF 1TWHE 3HKZK 4A3CF 5E17E 5IYCE 4A3EE 2WB1H 4OIOE 3GTPE 2JA8E 4C3JE 2E2JF 2B63E 5TMCE 1YNNK 3M4OF 4BBRF 2E2IE 5D4EE 5FLME 2NVQF 1TWHF 3GTLF 5IYCF 3S16E 4G7OE 4OIPE 4OIRE 1K83E 4C3JF 2B63F 2JA8F 4Y52E 1EIKA 1TWCF 2E2IF 5FLMF 4C2ME 5C4XE 2NVTE 3S16F 1K83F 3S15F 4QIWK 5M5XE 4A3GE 4Y52F 3RZDE 4C3HE 4GZYE 4C2MF 5C4XF 2NVTF 1I50F 2A6HE 1SFOE 5M5XF 4A3GF 3S14E 5IPLE 5IP9E 4C3HF 4A3JF 3RZDF 2WAQK 4YFXE 4XSZE 3HOUE 4MEYE 3GTJE 2A6EE 1SFOF 3S14F 5C4JE 4A93E 5IP9F 3WODE 3HOUF 1QKLA 2R92E 3GTJF 2VUME 4A3DE 5BYHE 4X6AE 5C4JF 4A3EF 4A93F 1TWAE 5C44E 3GTPF 4JK1E 2R92F 4A3BE 1IW7E 4KN4E 4Q5SE 4OIQE 2VUMF 4A3DF 2JA7E 4X6AF 4A3IE 1TWAF 5C44F 4MEXE 5M5YE 3DXJE 3PO2E 3S1ME 2A69E 4BY1E 4LK1E 4A3BF 4AYBK 2JA7F 4BY7E 4MQ9E 4A3IF 5M5YF 1YNJK 3PO2F 2O5IE 5C3EE 3S1MF 4BY1F 3S17E 3HOXE 4A3FE 3HOVE 3S1NE 3GTOE 4KMUE 3S2HE 3S1RE 4BY7F 4A3CE 1I3QE 1SMYE 4BBSE 4BXXE 4XLPE 1WCME 1Y1WE 5C3EF 3S17F 3HOXF 4LK0E 4A3FF 3S1QE 2PMZH 3GTOF 3HOVF 3S2HF 3S1NF 3HOZE 5D4CE 3S1RF 5M3FE 3H3VF 3K7AE 1I3QF 2A68E 3HKZH 4G7HE 3HOWE 1WCMF 2JA5E 2E2HE 4BBSF 3GTQE 5IP7E 3S1QF 3CQZE 4KN7E 3HOZF 4Y7NE 5M3FF 5IYDE 3K7AF 3HOWF 2JA5F 2E2HF 3GTQF 4YFNE 2NVYE 5IP7F 2YU9E 3CQZF 2Y0SI 4OINE 3I4NE 4Y7NF 2R93E 5IYDF 4A3LE 3I4ME 1HQME
chains in the Genus database with same CATH topology
2R7ZE 4QIWH 3GTKE 3FKIE 4A3ME 4AYBH 1TWGE 3GTGE 5FJ8E 5IYBE 2JA6E 1TWCE 2WAQH 4A3KE 1TWFE 3S15E 3M3YE 3PO3E 5M3ME 3HOYE 1DZFA 1I50E 1Y1VE 3H0GE 5M5WE 1I6HE 4A3JE 1R9TE 2Y0SH 4C3IE 2NVXE 3S2DE 3RZOE 3GTME 2E2JE 3M4OE 4BBRE 3GTLE 2NVQE 1TWHE 5IYCE 4A3EE 2WB1H 3GTPE 2JA8E 4C3JE 2B63E 2E2IE 5FLME 3S16E 1K83E 4Y52E 1EIKA 4C2ME 5C4XE 2NVTE 5M5XE 4A3GE 3RZDE 4C3HE 1SFOE 3S14E 5IP9E 3HOUE 3GTJE 5C4JE 4A93E 2R92E 2VUME 4A3DE 4X6AE 1TWAE 5C44E 4A3BE 2JA7E 4A3IE 5M5YE 3PO2E 3S1ME 4BY1E 4BY7E 5C3EE 3S17E 3HOXE 4A3FE 3HOVE 3S1NE 3GTOE 3S2HE 3S1RE 4A3CE 1I3QE 4BBSE 4BXXE 1WCME 1Y1WE 3S1QE 2PMZH 3HOZE 5M3FE 3H3VF 3K7AE 3HKZH 3HOWE 2JA5E 2E2HE 3GTQE 5IP7E 3CQZE 4Y7NE 5IYDE 2NVYE 2YU9E 3I4NE 2R93E 4A3LE 3I4ME
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2R7Z E;  4QIW H;  3GTK E;  3FKI E;  4A3M E;  4AYB H;  1TWG E;  3GTG E;  5FJ8 E;  5IYB E;  2JA6 E;  1TWC E;  2WAQ H;  4A3K E;  1TWF E;  3S15 E;  3M3Y E;  3PO3 E;  5M3M E;  3HOY E;  1DZF A;  1I50 E;  1Y1V E;  3H0G E;  5M5W E;  1I6H E;  4A3J E;  1R9T E;  2Y0S H;  4C3I E;  2NVX E;  3S2D E;  3RZO E;  3GTM E;  2E2J E;  3M4O E;  4BBR E;  3GTL E;  2NVQ E;  1TWH E;  5IYC E;  4A3E E;  2WB1 H;  3GTP E;  2JA8 E;  4C3J E;  2B63 E;  2E2I E;  5FLM E;  3S16 E;  1K83 E;  4Y52 E;  1EIK A;  4C2M E;  5C4X E;  2NVT E;  5M5X E;  4A3G E;  3RZD E;  4C3H E;  1SFO E;  3S14 E;  5IP9 E;  3HOU E;  3GTJ E;  5C4J E;  4A93 E;  2R92 E;  2VUM E;  4A3D E;  4X6A E;  1TWA E;  5C44 E;  4A3B E;  2JA7 E;  4A3I E;  5M5Y E;  3PO2 E;  3S1M E;  4BY1 E;  4BY7 E;  5C3E E;  3S17 E;  3HOX E;  4A3F E;  3HOV E;  3S1N E;  3GTO E;  3S2H E;  3S1R E;  4A3C E;  1I3Q E;  4BBS E;  4BXX E;  1WCM E;  1Y1W E;  3S1Q E;  2PMZ H;  3HOZ E;  5M3F E;  3H3V F;  3K7A E;  3HKZ H;  3HOW E;  2JA5 E;  2E2H E;  3GTQ E;  5IP7 E;  3CQZ E;  4Y7N E;  5IYD E;  2NVY E;  2YU9 E;  3I4N E;  2R93 E;  4A3L E;  3I4M E; 
#chains in the Genus database with same CATH topology
 2NVY F;  2R7Z E;  4QIW H;  2YU9 F;  3GTK E;  3I4N F;  3FKI E;  4ZH4 E;  2R93 F;  4A3M E;  4AYB H;  4LLG E;  2BE5 E;  1TWG E;  3I4M F;  2WB1 I;  2R7Z F;  3GTG E;  5FJ8 E;  3GTK F;  5IYB E;  3FKI F;  2JA6 E;  2KRX A;  1TWC E;  2WAQ H;  4A3M F;  4A3K E;  1TWG F;  2CW0 E;  4XLN E;  1TWF E;  3GTG F;  3S15 E;  5FJ8 F;  5IYB F;  4G7Z E;  3M3Y E;  2JA6 F;  5D4D E;  1Y1W F;  4BXX F;  4A3K F;  3PO3 E;  5M3M E;  3HOY E;  1DZF A;  1TWF F;  1I50 E;  1Y1V E;  3H0G E;  3M3Y F;  5M5W E;  4LJZ E;  1I6H E;  4A3J E;  3PO3 F;  2O5J E;  5M3M F;  3HOY F;  1R9T E;  2Y0S H;  5E18 E;  4C3I E;  2NVX E;  3S2D E;  1Y1V F;  3RZO E;  3EQL E;  3GTM E;  3H0G F;  5TMF E;  4Q4Z E;  1I6V E;  5M5W F;  1I6H F;  4XSX E;  2PPB E;  1ZYR E;  1R9T F;  2E2J E;  3H3V G;  4YG2 E;  4YFK E;  2PMZ K;  4C3I F;  2NVX F;  3M4O E;  3S2D F;  4BBR E;  3RZO F;  3GTM F;  3GTL E;  2NVQ E;  4A3L F;  1TWH E;  3HKZ K;  4A3C F;  5E17 E;  5IYC E;  4A3E E;  2WB1 H;  4OIO E;  3GTP E;  2JA8 E;  4C3J E;  2E2J F;  2B63 E;  5TMC E;  1YNN K;  3M4O F;  4BBR F;  2E2I E;  5D4E E;  5FLM E;  2NVQ F;  1TWH F;  3GTL F;  5IYC F;  3S16 E;  4G7O E;  4OIP E;  4OIR E;  1K83 E;  4C3J F;  2B63 F;  2JA8 F;  4Y52 E;  1EIK A;  1TWC F;  2E2I F;  5FLM F;  4C2M E;  5C4X E;  2NVT E;  3S16 F;  1K83 F;  3S15 F;  4QIW K;  5M5X E;  4A3G E;  4Y52 F;  3RZD E;  4C3H E;  4GZY E;  4C2M F;  5C4X F;  2NVT F;  1I50 F;  2A6H E;  1SFO E;  5M5X F;  4A3G F;  3S14 E;  5IPL E;  5IP9 E;  4C3H F;  4A3J F;  3RZD F;  2WAQ K;  4YFX E;  4XSZ E;  3HOU E;  4MEY E;  3GTJ E;  2A6E E;  1SFO F;  3S14 F;  5C4J E;  4A93 E;  5IP9 F;  3WOD E;  3HOU F;  1QKL A;  2R92 E;  3GTJ F;  2VUM E;  4A3D E;  5BYH E;  4X6A E;  5C4J F;  4A3E F;  4A93 F;  1TWA E;  5C44 E;  3GTP F;  4JK1 E;  2R92 F;  4A3B E;  1IW7 E;  4KN4 E;  4Q5S E;  4OIQ E;  2VUM F;  4A3D F;  2JA7 E;  4X6A F;  4A3I E;  1TWA F;  5C44 F;  4MEX E;  5M5Y E;  3DXJ E;  3PO2 E;  3S1M E;  2A69 E;  4BY1 E;  4LK1 E;  4A3B F;  4AYB K;  2JA7 F;  4BY7 E;  4MQ9 E;  4A3I F;  5M5Y F;  1YNJ K;  3PO2 F;  2O5I E;  5C3E E;  3S1M F;  4BY1 F;  3S17 E;  3HOX E;  4A3F E;  3HOV E;  3S1N E;  3GTO E;  4KMU E;  3S2H E;  3S1R E;  4BY7 F;  4A3C E;  1I3Q E;  1SMY E;  4BBS E;  4BXX E;  4XLP E;  1WCM E;  1Y1W E;  5C3E F;  3S17 F;  3HOX F;  4LK0 E;  4A3F F;  3S1Q E;  2PMZ H;  3GTO F;  3HOV F;  3S2H F;  3S1N F;  3HOZ E;  5D4C E;  3S1R F;  5M3F E;  3H3V F;  3K7A E;  1I3Q F;  2A68 E;  3HKZ H;  4G7H E;  3HOW E;  1WCM F;  2JA5 E;  2E2H E;  4BBS F;  3GTQ E;  5IP7 E;  3S1Q F;  3CQZ E;  4KN7 E;  3HOZ F;  4Y7N E;  5M3F F;  5IYD E;  3K7A F;  3HOW F;  2JA5 F;  2E2H F;  3GTQ F;  4YFN E;  2NVY E;  5IP7 F;  2YU9 E;  3CQZ F;  2Y0S I;  4OIN E;  3I4N E;  4Y7N F;  2R93 E;  5IYD F;  4A3L E;  3I4M E;  1HQM E; 
#chains in the Genus database with same CATH homology
 2R7Z E;  4QIW H;  3GTK E;  3FKI E;  4A3M E;  4AYB H;  1TWG E;  3GTG E;  5FJ8 E;  5IYB E;  2JA6 E;  1TWC E;  2WAQ H;  4A3K E;  1TWF E;  3S15 E;  3M3Y E;  3PO3 E;  5M3M E;  3HOY E;  1DZF A;  1I50 E;  1Y1V E;  3H0G E;  5M5W E;  1I6H E;  4A3J E;  1R9T E;  2Y0S H;  4C3I E;  2NVX E;  3S2D E;  3RZO E;  3GTM E;  2E2J E;  3M4O E;  4BBR E;  3GTL E;  2NVQ E;  1TWH E;  5IYC E;  4A3E E;  2WB1 H;  3GTP E;  2JA8 E;  4C3J E;  2B63 E;  2E2I E;  5FLM E;  3S16 E;  1K83 E;  4Y52 E;  1EIK A;  4C2M E;  5C4X E;  2NVT E;  5M5X E;  4A3G E;  3RZD E;  4C3H E;  1SFO E;  3S14 E;  5IP9 E;  3HOU E;  3GTJ E;  5C4J E;  4A93 E;  2R92 E;  2VUM E;  4A3D E;  4X6A E;  1TWA E;  5C44 E;  4A3B E;  2JA7 E;  4A3I E;  5M5Y E;  3PO2 E;  3S1M E;  4BY1 E;  4BY7 E;  5C3E E;  3S17 E;  3HOX E;  4A3F E;  3HOV E;  3S1N E;  3GTO E;  3S2H E;  3S1R E;  4A3C E;  1I3Q E;  4BBS E;  4BXX E;  1WCM E;  1Y1W E;  3S1Q E;  2PMZ H;  3HOZ E;  5M3F E;  3H3V F;  3K7A E;  3HKZ H;  3HOW E;  2JA5 E;  2E2H E;  3GTQ E;  5IP7 E;  3CQZ E;  4Y7N E;  5IYD E;  2NVY E;  2YU9 E;  3I4N E;  2R93 E;  4A3L E;  3I4M E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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