4Y7NE

The structure insight into 5-carboxycytosine recognition by rna polymerase ii during transcription elongation.
Total Genus 53
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
53
sequence length
214
structure length
214
Chain Sequence
DQENERNISRLWRAFRTVKEMVKDRGYFITQEEVELPLEDFKAKYCDSMGRPQRKMMSFQANPTEESISKFPDMGSLWVEFCDEPSVGVKTMKTFVIHIQEKNFQTGIFVYQNNITPSAMKLVPSIPPATIETFNEAALVVNITHHELVPKHIRLSSDEKRELLKRYRLKESQLPRIQRADPVALYLGLKRGEVVKIIRKSETSGRYASYRICM
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Molecular basis for 5-carboxycytosine recognition by RNA polymerase II elongation complex.
pubmed doi rcsb
molecule tags Transcription/dna/rna
molecule keywords DNA-directed RNA polymerase II subunit RPB1
total genus 53
structure length 214
sequence length 214
ec nomenclature
pdb deposition date 2015-02-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF01191 RNA_pol_Rpb5_C RNA polymerase Rpb5, C-terminal domain
E PF03871 RNA_pol_Rpb5_N RNA polymerase Rpb5, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1340.10 Alpha Beta 3-Layer(aba) Sandwich Dna-directed Rna Polymerases I, Ii, And Iii 27 Kd Polypeptide; Chain: A; domain 1 RNA polymerase, Rpb5, N-terminal domain 4y7nE01
3.90.940.20 Alpha Beta Alpha-Beta Complex Eukaryotic RPB6 RNA polymerase subunit RPB5-like RNA polymerase subunit 4y7nE02
3GTJE 2R92E 5M5XE 3S2DE 5FLME 1K83E 2E2JE 3S14E 1DZFA 4Y52E 3GTME 1I50E 5IP7E 4BY7E 2Y0SH 4C3JE 3H0GE 1I6HE 3S1RE 3S15E 1I3QE 5C3EE 2JA6E 5C44E 2JA7E 4Y7NE 3HOYE 1Y1WE 2NVQE 3GTGE 5M5YE 5IYDE 4A3KE 3HOUE 1TWGE 4A93E 3GTKE 3HOZE 3GTQE 1TWCE 5M3ME 3M3YE 1EIKA 3S2HE 2JA5E 4A3CE 2R93E 2R7ZE 1R9TE 4C3HE 4BBSE 3H3VF 4A3FE 4BXXE 3GTOE 1TWAE 4A3DE 2YU9E 4A3JE 3S17E 5C4XE 3S1ME 3PO3E 3CQZE 4AYBH 4C2ME 2WB1H 2NVYE 5IYCE 5FJ8E 4A3IE 3K7AE 3GTLE 4A3BE 5M5WE 5C4JE 2JA8E 3I4NE 1TWHE 3PO2E 4BY1E 2E2IE 4X6AE 2WAQH 4A3EE 4A3ME 2VUME 2NVTE 2PMZH 3RZOE 4A3LE 3RZDE 3M4OE 1SFOE 1Y1VE 3HOXE 2E2HE 1WCME 3GTPE 5IYBE 2NVXE 3HOVE 3I4ME 3S1QE 3S16E 4BBRE 4C3IE 4A3GE 3S1NE 3HOWE 1TWFE 3FKIE 5IP9E 5M3FE 2B63E 3HKZH 4QIWH
chains in the Genus database with same CATH superfamily
5M5WF 3GTJE 2R92E 5M5XE 3S2DE 5C4JF 1SMYE 3GTPF 3I4NF 4MEYE 4YFNE 5FLME 3S1QF 1YNNK 4OIPE 3PO2F 4BY1F 1K83E 2E2JE 2E2IF 3S14E 1DZFA 4Y52E 3FKIF 4X6AF 3GTME 1I50E 2A68E 5IP7E 4LJZE 2B63F 4BY7E 4QIWK 4XSXE 4G7OE 2NVTF 2VUMF 2Y0SH 3GTJF 5M5XF 4YG2E 3RZOF 4GZYE 4LLGE 4XLNE 2BE5E 4C3JE 3H0GE 1I6HE 3EQLE 4A3LF 3RZDF 3S1RE 3S15E 4G7ZE 1I3QE 5C3EE 2JA6E 5C44E 1QKLA 2A69E 5D4EE 1SFOF 1Y1VF 2JA7E 2E2JF 2O5IE 2E2HF 3M4OF 4Y7NE 3HOYE 5IPLE 1Y1WE 2NVQE 1I50F 3GTMF 3GTGE 5M5YE 5IYDE 1WCMF 2KRXA 4A3KE 5D4CE 3HOUE 1TWGE 4A93E 5IYBF 3GTKE 3HOZE 4XLPE 2NVXF 3HOVF 3I4MF 3GTQE 1TWCE 4OIQE 5M3ME 3S16F 4BBRF 4C3IF 3M3YE 3S1RF 3S1NF 4A3GF 1EIKA 1I3QF 4LK1E 1TWFF 2Y0SI 5C3EF 3HOWF 5IP9F 5M3FF 2JA7F 4YFXE 3S2HE 4AYBK 2NVQF 2JA5E 4KN7E 4A3CE 3GTGF 2PPBE 2R93E 4Q5SE 2R92F 2R7ZE 1R9TE 4XSZE 4C3HE 4A3KF 4BBSE 3HOUF 1TWGF 3S2DF 1ZYRE 4OIOE 4MQ9E 3GTKF 3HOZF 3H3VF 4A3FE 4BXXE 5FLMF 3GTQF 3GTOE 1TWAE 4A3DE 2YU9E 4A3JE 3S17E 5C4XE 1K83F 3S14F 3S1ME 2A6EE 4Y52F 3PO3E 5TMFE 3CQZE 4AYBH 5IP7F 4C2ME 3S2HF 4BY7F 4OINE 4A93F 4KN4E 5BYHE 2WB1H 2NVYE 2R7ZF 5IYCE 5FJ8E 4BBSF 4A3IE 2WAQK 3K7AE 3GTLE 3H0GF 4C3JF 4A3BE 1I6HF 3S15F 5M5WE 1TWAF 5C4JE 2JA6F 5C44F 2JA8E 3I4NE 4Y7NF 3HOYF 3PO3F 1Y1WF 3CQZF 1TWHE 3PO2E 4BY1E 4C2MF 5M5YF 5IYDF 4Q4ZE 2E2IE 2O5JE 4YFKE 3WODE 2NVYF 4X6AE 2WAQH 4A3EE 4A3ME 1TWCF 3GTLF 5M3MF 3DXJE 4KMUE 2VUME 2NVTE 3M3YF 2PMZH 2WB1I 3RZOE 1HQME 2JA8F 4A3LE 1YNJK 3RZDE 1TWHF 2JA5F 4A3CF 5TMCE 3M4OE 2R93F 1SFOE 1Y1VE 5D4DE 3HOXE 2E2HE 1R9TF 4C3HF 1I6VE 4JK1E 4G7HE 5E18E 4BXXF 4A3FF 3HKZK 4A3EF 1WCME 4A3MF 3GTOF 4A3DF 3GTPE 2PMZK 2YU9F 4A3JF 3S17F 5C4XF 5IYBE 3S1MF 2NVXE 3H3VG 3HOVE 3I4ME 3S1QE 3S16E 4BBRE 4C3IE 4A3GE 3S1NE 3HOWE 1IW7E 1TWFE 4MEXE 3FKIE 5IP9E 5M3FE 2A6HE 3HOXF 4OIRE 5IYCF 5FJ8F 5E17E 2B63E 4LK0E 4A3IF 3K7AF 3HKZH 2CW0E 4QIWH 4A3BF 4ZH4E
chains in the Genus database with same CATH topology
3GTJE 2R92E 5M5XE 3S2DE 5FLME 1K83E 2E2JE 3S14E 1DZFA 4Y52E 3GTME 1I50E 5IP7E 4BY7E 2Y0SH 4C3JE 3H0GE 1I6HE 3S1RE 3S15E 1I3QE 5C3EE 2JA6E 5C44E 2JA7E 4Y7NE 3HOYE 1Y1WE 2NVQE 3GTGE 5M5YE 5IYDE 4A3KE 3HOUE 1TWGE 4A93E 3GTKE 3HOZE 3GTQE 1TWCE 5M3ME 3M3YE 1EIKA 3S2HE 2JA5E 4A3CE 2R93E 2R7ZE 1R9TE 4C3HE 4BBSE 3H3VF 4A3FE 4BXXE 3GTOE 1TWAE 4A3DE 2YU9E 4A3JE 3S17E 5C4XE 3S1ME 3PO3E 3CQZE 4AYBH 4C2ME 2WB1H 2NVYE 5IYCE 5FJ8E 4A3IE 3K7AE 3GTLE 4A3BE 5M5WE 5C4JE 2JA8E 3I4NE 1TWHE 3PO2E 4BY1E 2E2IE 4X6AE 2WAQH 4A3EE 4A3ME 2VUME 2NVTE 2PMZH 3RZOE 4A3LE 3RZDE 3M4OE 1SFOE 1Y1VE 3HOXE 2E2HE 1WCME 3GTPE 5IYBE 2NVXE 3HOVE 3I4ME 3S1QE 3S16E 4BBRE 4C3IE 4A3GE 3S1NE 3HOWE 1TWFE 3FKIE 5IP9E 5M3FE 2B63E 3HKZH 4QIWH
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3GTJ E;  2R92 E;  5M5X E;  3S2D E;  5FLM E;  1K83 E;  2E2J E;  3S14 E;  1DZF A;  4Y52 E;  3GTM E;  1I50 E;  5IP7 E;  4BY7 E;  2Y0S H;  4C3J E;  3H0G E;  1I6H E;  3S1R E;  3S15 E;  1I3Q E;  5C3E E;  2JA6 E;  5C44 E;  2JA7 E;  4Y7N E;  3HOY E;  1Y1W E;  2NVQ E;  3GTG E;  5M5Y E;  5IYD E;  4A3K E;  3HOU E;  1TWG E;  4A93 E;  3GTK E;  3HOZ E;  3GTQ E;  1TWC E;  5M3M E;  3M3Y E;  1EIK A;  3S2H E;  2JA5 E;  4A3C E;  2R93 E;  2R7Z E;  1R9T E;  4C3H E;  4BBS E;  3H3V F;  4A3F E;  4BXX E;  3GTO E;  1TWA E;  4A3D E;  2YU9 E;  4A3J E;  3S17 E;  5C4X E;  3S1M E;  3PO3 E;  3CQZ E;  4AYB H;  4C2M E;  2WB1 H;  2NVY E;  5IYC E;  5FJ8 E;  4A3I E;  3K7A E;  3GTL E;  4A3B E;  5M5W E;  5C4J E;  2JA8 E;  3I4N E;  1TWH E;  3PO2 E;  4BY1 E;  2E2I E;  4X6A E;  2WAQ H;  4A3E E;  4A3M E;  2VUM E;  2NVT E;  2PMZ H;  3RZO E;  4A3L E;  3RZD E;  3M4O E;  1SFO E;  1Y1V E;  3HOX E;  2E2H E;  1WCM E;  3GTP E;  5IYB E;  2NVX E;  3HOV E;  3I4M E;  3S1Q E;  3S16 E;  4BBR E;  4C3I E;  4A3G E;  3S1N E;  3HOW E;  1TWF E;  3FKI E;  5IP9 E;  5M3F E;  2B63 E;  3HKZ H;  4QIW H; 
#chains in the Genus database with same CATH topology
 5M5W F;  3GTJ E;  2R92 E;  5M5X E;  3S2D E;  5C4J F;  1SMY E;  3GTP F;  3I4N F;  4MEY E;  4YFN E;  5FLM E;  3S1Q F;  1YNN K;  4OIP E;  3PO2 F;  4BY1 F;  1K83 E;  2E2J E;  2E2I F;  3S14 E;  1DZF A;  4Y52 E;  3FKI F;  4X6A F;  3GTM E;  1I50 E;  2A68 E;  5IP7 E;  4LJZ E;  2B63 F;  4BY7 E;  4QIW K;  4XSX E;  4G7O E;  2NVT F;  2VUM F;  2Y0S H;  3GTJ F;  5M5X F;  4YG2 E;  3RZO F;  4GZY E;  4LLG E;  4XLN E;  2BE5 E;  4C3J E;  3H0G E;  1I6H E;  3EQL E;  4A3L F;  3RZD F;  3S1R E;  3S15 E;  4G7Z E;  1I3Q E;  5C3E E;  2JA6 E;  5C44 E;  1QKL A;  2A69 E;  5D4E E;  1SFO F;  1Y1V F;  2JA7 E;  2E2J F;  2O5I E;  2E2H F;  3M4O F;  4Y7N E;  3HOY E;  5IPL E;  1Y1W E;  2NVQ E;  1I50 F;  3GTM F;  3GTG E;  5M5Y E;  5IYD E;  1WCM F;  2KRX A;  4A3K E;  5D4C E;  3HOU E;  1TWG E;  4A93 E;  5IYB F;  3GTK E;  3HOZ E;  4XLP E;  2NVX F;  3HOV F;  3I4M F;  3GTQ E;  1TWC E;  4OIQ E;  5M3M E;  3S16 F;  4BBR F;  4C3I F;  3M3Y E;  3S1R F;  3S1N F;  4A3G F;  1EIK A;  1I3Q F;  4LK1 E;  1TWF F;  2Y0S I;  5C3E F;  3HOW F;  5IP9 F;  5M3F F;  2JA7 F;  4YFX E;  3S2H E;  4AYB K;  2NVQ F;  2JA5 E;  4KN7 E;  4A3C E;  3GTG F;  2PPB E;  2R93 E;  4Q5S E;  2R92 F;  2R7Z E;  1R9T E;  4XSZ E;  4C3H E;  4A3K F;  4BBS E;  3HOU F;  1TWG F;  3S2D F;  1ZYR E;  4OIO E;  4MQ9 E;  3GTK F;  3HOZ F;  3H3V F;  4A3F E;  4BXX E;  5FLM F;  3GTQ F;  3GTO E;  1TWA E;  4A3D E;  2YU9 E;  4A3J E;  3S17 E;  5C4X E;  1K83 F;  3S14 F;  3S1M E;  2A6E E;  4Y52 F;  3PO3 E;  5TMF E;  3CQZ E;  4AYB H;  5IP7 F;  4C2M E;  3S2H F;  4BY7 F;  4OIN E;  4A93 F;  4KN4 E;  5BYH E;  2WB1 H;  2NVY E;  2R7Z F;  5IYC E;  5FJ8 E;  4BBS F;  4A3I E;  2WAQ K;  3K7A E;  3GTL E;  3H0G F;  4C3J F;  4A3B E;  1I6H F;  3S15 F;  5M5W E;  1TWA F;  5C4J E;  2JA6 F;  5C44 F;  2JA8 E;  3I4N E;  4Y7N F;  3HOY F;  3PO3 F;  1Y1W F;  3CQZ F;  1TWH E;  3PO2 E;  4BY1 E;  4C2M F;  5M5Y F;  5IYD F;  4Q4Z E;  2E2I E;  2O5J E;  4YFK E;  3WOD E;  2NVY F;  4X6A E;  2WAQ H;  4A3E E;  4A3M E;  1TWC F;  3GTL F;  5M3M F;  3DXJ E;  4KMU E;  2VUM E;  2NVT E;  3M3Y F;  2PMZ H;  2WB1 I;  3RZO E;  1HQM E;  2JA8 F;  4A3L E;  1YNJ K;  3RZD E;  1TWH F;  2JA5 F;  4A3C F;  5TMC E;  3M4O E;  2R93 F;  1SFO E;  1Y1V E;  5D4D E;  3HOX E;  2E2H E;  1R9T F;  4C3H F;  1I6V E;  4JK1 E;  4G7H E;  5E18 E;  4BXX F;  4A3F F;  3HKZ K;  4A3E F;  1WCM E;  4A3M F;  3GTO F;  4A3D F;  3GTP E;  2PMZ K;  2YU9 F;  4A3J F;  3S17 F;  5C4X F;  5IYB E;  3S1M F;  2NVX E;  3H3V G;  3HOV E;  3I4M E;  3S1Q E;  3S16 E;  4BBR E;  4C3I E;  4A3G E;  3S1N E;  3HOW E;  1IW7 E;  1TWF E;  4MEX E;  3FKI E;  5IP9 E;  5M3F E;  2A6H E;  3HOX F;  4OIR E;  5IYC F;  5FJ8 F;  5E17 E;  2B63 E;  4LK0 E;  4A3I F;  3K7A F;  3HKZ H;  2CW0 E;  4QIW H;  4A3B F;  4ZH4 E; 
#chains in the Genus database with same CATH homology
 3GTJ E;  2R92 E;  5M5X E;  3S2D E;  5FLM E;  1K83 E;  2E2J E;  3S14 E;  1DZF A;  4Y52 E;  3GTM E;  1I50 E;  5IP7 E;  4BY7 E;  2Y0S H;  4C3J E;  3H0G E;  1I6H E;  3S1R E;  3S15 E;  1I3Q E;  5C3E E;  2JA6 E;  5C44 E;  2JA7 E;  4Y7N E;  3HOY E;  1Y1W E;  2NVQ E;  3GTG E;  5M5Y E;  5IYD E;  4A3K E;  3HOU E;  1TWG E;  4A93 E;  3GTK E;  3HOZ E;  3GTQ E;  1TWC E;  5M3M E;  3M3Y E;  1EIK A;  3S2H E;  2JA5 E;  4A3C E;  2R93 E;  2R7Z E;  1R9T E;  4C3H E;  4BBS E;  3H3V F;  4A3F E;  4BXX E;  3GTO E;  1TWA E;  4A3D E;  2YU9 E;  4A3J E;  3S17 E;  5C4X E;  3S1M E;  3PO3 E;  3CQZ E;  4AYB H;  4C2M E;  2WB1 H;  2NVY E;  5IYC E;  5FJ8 E;  4A3I E;  3K7A E;  3GTL E;  4A3B E;  5M5W E;  5C4J E;  2JA8 E;  3I4N E;  1TWH E;  3PO2 E;  4BY1 E;  2E2I E;  4X6A E;  2WAQ H;  4A3E E;  4A3M E;  2VUM E;  2NVT E;  2PMZ H;  3RZO E;  4A3L E;  3RZD E;  3M4O E;  1SFO E;  1Y1V E;  3HOX E;  2E2H E;  1WCM E;  3GTP E;  5IYB E;  2NVX E;  3HOV E;  3I4M E;  3S1Q E;  3S16 E;  4BBR E;  4C3I E;  4A3G E;  3S1N E;  3HOW E;  1TWF E;  3FKI E;  5IP9 E;  5M3F E;  2B63 E;  3HKZ H;  4QIW H; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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