4YG2E

X-ray crystal structur of escherichia coli rna polymerase sigma70 holoenzyme
Total Genus 25
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
25
sequence length
89
structure length
89
Chain Sequence
ARVTVQDAVEKIGNRFDLVLVAARRARQMQVGGKDPLVPEENDKTTVIALREIEEGLINNQILDVRERQEQQEQEAAELQAVTAIAEGR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title X-ray crystal structure of Escherichia coli RNA polymerase sigma70 holoenzyme
pubmed doi rcsb
molecule tags Transferase/transcription
source organism Escherichia coli o157:h7
molecule keywords DNA-directed RNA polymerase subunit alpha
total genus 25
structure length 89
sequence length 89
chains with identical sequence K
ec nomenclature ec 2.7.7.6: DNA-directed RNA polymerase.
pdb deposition date 2015-02-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF01192 RNA_pol_Rpb6 RNA polymerase Rpb6
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.940.10 Alpha Beta Alpha-Beta Complex Eukaryotic RPB6 RNA polymerase subunit Eukaryotic RPB6 RNA polymerase subunit 4yg2E00
3RZDF 4BXXF 4OINE 4GZYE 2A68E 3GTOF 4C2MF 5E17E 3GTQF 4A3CF 1ZYRE 5IYDF 3S1MF 3HKZK 4OIRE 5C4JF 4KMUE 4A3JF 4OIPE 5D4CE 3GTJF 3S2DF 2JA7F 2WB1I 2O5IE 3HOYF 3M4OF 4OIQE 3GTPF 2E2HF 3S14F 4KN7E 4Y7NF 3HOZF 4G7ZE 4X6AF 2BE5E 3S15F 4A3DF 3S2HF 4A3BF 3I4NF 2JA8F 1I3QF 1TWCF 4YFNE 1SMYE 2R93F 3H0GF 1YNNK 5C4XF 1TWGF 4MEYE 3M3YF 3S1NF 3HOWF 4C3JF 2JA6F 3GTKF 1IW7E 5C3EF 5IYCF 4XLNE 3H3VG 4YFKE 3HOVF 3S17F 5BYHE 2CW0E 1Y1WF 3CQZF 4ZH4E 3HOXF 1SFOF 1TWAF 4A3FF 2VUMF 5D4DE 3S1RF 2PPBE 4AYBK 5IP7F 3PO2F 2YU9F 2B63F 3FKIF 4LLGE 3GTLF 4YG2E 5E18E 5FJ8F 1TWHF 5C44F 4LK0E 1TWFF 5M5XF 5FLMF 3S1QF 2E2IF 4LJZE 3WODE 5D4EE 1HQME 4YFXE 3HOUF 5IP9F 4Q4ZE 2E2JF 4LK1E 4BBSF 5IPLE 4A3KF 3EQLE 2NVQF 1I6HF 2A6EE 3GTGF 4OIOE 3I4MF 2O5JE 1QKLA 5M3FF 4BY7F 1I6VE 5TMFE 2WAQK 4A3IF 4A3LF 2NVXF 4Y52F 2Y0SI 4MQ9E 4XSZE 1K83F 2A6HE 4Q5SE 4A3MF 3RZOF 4BY1F 1YNJK 4BBRF 3DXJE 4A3GF 5M3MF 2PMZK 5M5WF 4A3EF 4MEXE 3S16F 1Y1VF 4JK1E 4XLPE 4KN4E 4A93F 2NVYF 3GTMF 4C3HF 5M5YF 4G7HE 4C3IF 3PO3F 1WCMF 4G7OE 2R92F 2A69E 1R9TF 5TMCE 3K7AF 4XSXE 2JA5F 2R7ZF 5IYBF 2NVTF 1I50F
chains in the Genus database with same CATH superfamily
3RZDF 4BXXF 4A3ME 4OINE 2A68E 3GTOF 4C2MF 4BBRE 4BY1E 3RZOE 4GZYE 5E17E 3GTQF 4A3CF 5C4JE 4A3GE 1ZYRE 5M5WE 5IYDF 4A3EE 3S16E 3S1MF 1Y1VE 3S2DE 3HKZK 4OIRE 5C4JF 4A93E 4KMUE 2NVYE 4A3JF 4OIPE 5D4CE 3GTJF 3S2DF 5M5YE 2JA7F 2WB1I 4C3IE 2O5IE 3M4OF 3PO3E 3HOYF 4OIQE 3GTPF 2R92E 4X6AE 2E2HF 3S14F 4A3DE 4KN7E 4Y7NF 2JA5E 3HOZF 3I4NE 4G7ZE 4X6AF 2BE5E 5IYBE 2NVTE 1I50E 3S15F 3RZDE 1DZFA 3S2HF 4A3BF 4BXXE 4A3DF 2R93E 3I4NF 3GTOE 4C2ME 2JA8F 1I3QF 1TWCF 4YFNE 3GTQE 1SMYE 4A3CE 2R93F 5C4XE 3H0GF 5IYDE 3S1ME 1YNNK 5C4XF 1TWGF 3GTKE 4A3JE 4MEYE 3GTJE 3M3YF 3S1NF 4AYBH 3HOWF 4C3JF 2JA7E 3HOYE 3M4OE 2JA6F 2Y0SH 3GTKF 1IW7E 3GTPE 5C3EF 5IYCF 4XLNE 2E2HE 4YFKE 3H3VG 3HOVF 3S14E 3S17F 4Y7NE 5BYHE 3HOZE 2CW0E 1Y1WF 3CQZF 4ZH4E 3HOXF 1SFOF 2B63E 1TWAF 3S15E 4A3FF 2VUMF 5D4DE 3GTLE 3S2HE 4A3BE 3S1RF 2PPBE 4AYBK 5IP7F 3PO2F 5FJ8E 1TWHE 1I3QE 1TWCE 2YU9F 2B63F 3FKIF 5FLME 2JA8E 4LLGE 3H0GE 3GTLF 4YG2E 5E18E 5FJ8F 1TWHF 5C44F 4LK0E 1TWFF 5M5XF 5FLMF 3S1QF 1TWGE 2E2IF 4LJZE 4BBSE 3WODE 3H3VF 5D4EE 1HQME 4YFXE 4A3KE 2KRXA 3HOUF 5IP9F 3M3YE 4Q4ZE 3HOWE 4C3JE 3S1NE 2E2JF 4LK1E 2JA6E 4BBSF 4QIWK 5IPLE 5C3EE 5IYCE 3EQLE 2WAQH 4A3KF 3HOVE 3S17E 1Y1WE 2NVQF 1EIKA 3CQZE 1I6HF 3HOXE 1SFOE 2A6EE 1TWAE 4BY7E 4A3FE 2VUME 3GTGF 3S1RE 4OIOE 3I4MF 5IP7E 3PO2E 2YU9E 2O5JE 1QKLA 3FKIE 4BY7F 1I6VE 5M3FF 5TMFE 4Y52E 2WAQK 2PMZH 5C44E 3S1QE 4QIWH 4A3IF 2WB1H 1TWFE 5M5XE 4A3LF 2NVXF 2E2IE 4Y52F 2Y0SI 4MQ9E 3HOUE 4XSZE 5IP9E 1K83F 2A6HE 5M3ME 2E2JE 4Q5SE 4A3MF 3RZOF 4BY1F 1YNJK 4BBRF 5IYBF 3DXJE 4A3GF 5M3MF 2PMZK 2NVQE 5M5WF 3GTME 4A3EF 4MEXE 3S16F 1Y1VF 1I6HE 4JK1E 4C3HE 4XLPE 4KN4E 4A93F 1WCME 3GTGE 2NVYF 3I4ME 3GTMF 1R9TE 4C3HF 3K7AE 5M3FE 5M5YF 4G7HE 4C3IF 3PO3F 1WCMF 2R7ZE 4G7OE 2R92F 2A69E 1R9TF 5TMCE 4A3IE 4A3LE 3K7AF 4XSXE 3HKZH 2JA5F 2NVXE 2R7ZF 1K83E 2NVTF 1I50F
chains in the Genus database with same CATH topology
3RZDF 4BXXF 4OINE 4GZYE 2A68E 3GTOF 4C2MF 5E17E 3GTQF 4A3CF 1ZYRE 5IYDF 3S1MF 3HKZK 4OIRE 5C4JF 4KMUE 4A3JF 4OIPE 5D4CE 3GTJF 3S2DF 2JA7F 2WB1I 2O5IE 3HOYF 3M4OF 4OIQE 3GTPF 2E2HF 3S14F 4KN7E 4Y7NF 3HOZF 4G7ZE 4X6AF 2BE5E 3S15F 4A3DF 3S2HF 4A3BF 3I4NF 2JA8F 1I3QF 1TWCF 4YFNE 1SMYE 2R93F 3H0GF 1YNNK 5C4XF 1TWGF 4MEYE 3M3YF 3S1NF 3HOWF 4C3JF 2JA6F 3GTKF 1IW7E 5C3EF 5IYCF 4XLNE 3H3VG 4YFKE 3HOVF 3S17F 5BYHE 2CW0E 1Y1WF 3CQZF 4ZH4E 3HOXF 1SFOF 1TWAF 4A3FF 2VUMF 5D4DE 3S1RF 2PPBE 4AYBK 5IP7F 3PO2F 2YU9F 2B63F 3FKIF 4LLGE 3GTLF 4YG2E 5E18E 5FJ8F 1TWHF 5C44F 4LK0E 1TWFF 5M5XF 5FLMF 3S1QF 2E2IF 4LJZE 3WODE 5D4EE 1HQME 4YFXE 3HOUF 2KRXA 5IP9F 4Q4ZE 2E2JF 4LK1E 4BBSF 4QIWK 5IPLE 4A3KF 3EQLE 2NVQF 1I6HF 2A6EE 3GTGF 4OIOE 3I4MF 2O5JE 1QKLA 5M3FF 4BY7F 1I6VE 5TMFE 2WAQK 4A3IF 4A3LF 2NVXF 4Y52F 2Y0SI 4MQ9E 4XSZE 1K83F 2A6HE 4Q5SE 4A3MF 3RZOF 4BY1F 1YNJK 4BBRF 3DXJE 4A3GF 5M3MF 2PMZK 5M5WF 4A3EF 4MEXE 3S16F 1Y1VF 4JK1E 4XLPE 4KN4E 4A93F 2NVYF 3GTMF 4C3HF 5M5YF 4G7HE 4C3IF 3PO3F 1WCMF 4G7OE 2R92F 2A69E 1R9TF 5TMCE 3K7AF 4XSXE 2JA5F 2R7ZF 5IYBF 2NVTF 1I50F
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3RZD F;  4BXX F;  4OIN E;  4GZY E;  2A68 E;  3GTO F;  4C2M F;  5E17 E;  3GTQ F;  4A3C F;  1ZYR E;  5IYD F;  3S1M F;  3HKZ K;  4OIR E;  5C4J F;  4KMU E;  4A3J F;  4OIP E;  5D4C E;  3GTJ F;  3S2D F;  2JA7 F;  2WB1 I;  2O5I E;  3HOY F;  3M4O F;  4OIQ E;  3GTP F;  2E2H F;  3S14 F;  4KN7 E;  4Y7N F;  3HOZ F;  4G7Z E;  4X6A F;  2BE5 E;  3S15 F;  4A3D F;  3S2H F;  4A3B F;  3I4N F;  2JA8 F;  1I3Q F;  1TWC F;  4YFN E;  1SMY E;  2R93 F;  3H0G F;  1YNN K;  5C4X F;  1TWG F;  4MEY E;  3M3Y F;  3S1N F;  3HOW F;  4C3J F;  2JA6 F;  3GTK F;  1IW7 E;  5C3E F;  5IYC F;  4XLN E;  3H3V G;  4YFK E;  3HOV F;  3S17 F;  5BYH E;  2CW0 E;  1Y1W F;  3CQZ F;  4ZH4 E;  3HOX F;  1SFO F;  1TWA F;  4A3F F;  2VUM F;  5D4D E;  3S1R F;  2PPB E;  4AYB K;  5IP7 F;  3PO2 F;  2YU9 F;  2B63 F;  3FKI F;  4LLG E;  3GTL F;  4YG2 E;  5E18 E;  5FJ8 F;  1TWH F;  5C44 F;  4LK0 E;  1TWF F;  5M5X F;  5FLM F;  3S1Q F;  2E2I F;  4LJZ E;  3WOD E;  5D4E E;  1HQM E;  4YFX E;  3HOU F;  5IP9 F;  4Q4Z E;  2E2J F;  4LK1 E;  4BBS F;  5IPL E;  4A3K F;  3EQL E;  2NVQ F;  1I6H F;  2A6E E;  3GTG F;  4OIO E;  3I4M F;  2O5J E;  1QKL A;  5M3F F;  4BY7 F;  1I6V E;  5TMF E;  2WAQ K;  4A3I F;  4A3L F;  2NVX F;  4Y52 F;  2Y0S I;  4MQ9 E;  4XSZ E;  1K83 F;  2A6H E;  4Q5S E;  4A3M F;  3RZO F;  4BY1 F;  1YNJ K;  4BBR F;  3DXJ E;  4A3G F;  5M3M F;  2PMZ K;  5M5W F;  4A3E F;  4MEX E;  3S16 F;  1Y1V F;  4JK1 E;  4XLP E;  4KN4 E;  4A93 F;  2NVY F;  3GTM F;  4C3H F;  5M5Y F;  4G7H E;  4C3I F;  3PO3 F;  1WCM F;  4G7O E;  2R92 F;  2A69 E;  1R9T F;  5TMC E;  3K7A F;  4XSX E;  2JA5 F;  2R7Z F;  5IYB F;  2NVT F;  1I50 F; 
#chains in the Genus database with same CATH topology
 3RZD F;  4BXX F;  4A3M E;  4OIN E;  2A68 E;  3GTO F;  4C2M F;  4BBR E;  4BY1 E;  3RZO E;  4GZY E;  5E17 E;  3GTQ F;  4A3C F;  5C4J E;  4A3G E;  1ZYR E;  5M5W E;  5IYD F;  4A3E E;  3S16 E;  3S1M F;  1Y1V E;  3S2D E;  3HKZ K;  4OIR E;  5C4J F;  4A93 E;  4KMU E;  2NVY E;  4A3J F;  4OIP E;  5D4C E;  3GTJ F;  3S2D F;  5M5Y E;  2JA7 F;  2WB1 I;  4C3I E;  2O5I E;  3M4O F;  3PO3 E;  3HOY F;  4OIQ E;  3GTP F;  2R92 E;  4X6A E;  2E2H F;  3S14 F;  4A3D E;  4KN7 E;  4Y7N F;  2JA5 E;  3HOZ F;  3I4N E;  4G7Z E;  4X6A F;  2BE5 E;  5IYB E;  2NVT E;  1I50 E;  3S15 F;  3RZD E;  1DZF A;  3S2H F;  4A3B F;  4BXX E;  4A3D F;  2R93 E;  3I4N F;  3GTO E;  4C2M E;  2JA8 F;  1I3Q F;  1TWC F;  4YFN E;  3GTQ E;  1SMY E;  4A3C E;  2R93 F;  5C4X E;  3H0G F;  5IYD E;  3S1M E;  1YNN K;  5C4X F;  1TWG F;  3GTK E;  4A3J E;  4MEY E;  3GTJ E;  3M3Y F;  3S1N F;  4AYB H;  3HOW F;  4C3J F;  2JA7 E;  3HOY E;  3M4O E;  2JA6 F;  2Y0S H;  3GTK F;  1IW7 E;  3GTP E;  5C3E F;  5IYC F;  4XLN E;  2E2H E;  4YFK E;  3H3V G;  3HOV F;  3S14 E;  3S17 F;  4Y7N E;  5BYH E;  3HOZ E;  2CW0 E;  1Y1W F;  3CQZ F;  4ZH4 E;  3HOX F;  1SFO F;  2B63 E;  1TWA F;  3S15 E;  4A3F F;  2VUM F;  5D4D E;  3GTL E;  3S2H E;  4A3B E;  3S1R F;  2PPB E;  4AYB K;  5IP7 F;  3PO2 F;  5FJ8 E;  1TWH E;  1I3Q E;  1TWC E;  2YU9 F;  2B63 F;  3FKI F;  5FLM E;  2JA8 E;  4LLG E;  3H0G E;  3GTL F;  4YG2 E;  5E18 E;  5FJ8 F;  1TWH F;  5C44 F;  4LK0 E;  1TWF F;  5M5X F;  5FLM F;  3S1Q F;  1TWG E;  2E2I F;  4LJZ E;  4BBS E;  3WOD E;  3H3V F;  5D4E E;  1HQM E;  4YFX E;  4A3K E;  2KRX A;  3HOU F;  5IP9 F;  3M3Y E;  4Q4Z E;  3HOW E;  4C3J E;  3S1N E;  2E2J F;  4LK1 E;  2JA6 E;  4BBS F;  4QIW K;  5IPL E;  5C3E E;  5IYC E;  3EQL E;  2WAQ H;  4A3K F;  3HOV E;  3S17 E;  1Y1W E;  2NVQ F;  1EIK A;  3CQZ E;  1I6H F;  3HOX E;  1SFO E;  2A6E E;  1TWA E;  4BY7 E;  4A3F E;  2VUM E;  3GTG F;  3S1R E;  4OIO E;  3I4M F;  5IP7 E;  3PO2 E;  2YU9 E;  2O5J E;  1QKL A;  3FKI E;  4BY7 F;  1I6V E;  5M3F F;  5TMF E;  4Y52 E;  2WAQ K;  2PMZ H;  5C44 E;  3S1Q E;  4QIW H;  4A3I F;  2WB1 H;  1TWF E;  5M5X E;  4A3L F;  2NVX F;  2E2I E;  4Y52 F;  2Y0S I;  4MQ9 E;  3HOU E;  4XSZ E;  5IP9 E;  1K83 F;  2A6H E;  5M3M E;  2E2J E;  4Q5S E;  4A3M F;  3RZO F;  4BY1 F;  1YNJ K;  4BBR F;  5IYB F;  3DXJ E;  4A3G F;  5M3M F;  2PMZ K;  2NVQ E;  5M5W F;  3GTM E;  4A3E F;  4MEX E;  3S16 F;  1Y1V F;  1I6H E;  4JK1 E;  4C3H E;  4XLP E;  4KN4 E;  4A93 F;  1WCM E;  3GTG E;  2NVY F;  3I4M E;  3GTM F;  1R9T E;  4C3H F;  3K7A E;  5M3F E;  5M5Y F;  4G7H E;  4C3I F;  3PO3 F;  1WCM F;  2R7Z E;  4G7O E;  2R92 F;  2A69 E;  1R9T F;  5TMC E;  4A3I E;  4A3L E;  3K7A F;  4XSX E;  3HKZ H;  2JA5 F;  2NVX E;  2R7Z F;  1K83 E;  2NVT F;  1I50 F; 
#chains in the Genus database with same CATH homology
 3RZD F;  4BXX F;  4OIN E;  4GZY E;  2A68 E;  3GTO F;  4C2M F;  5E17 E;  3GTQ F;  4A3C F;  1ZYR E;  5IYD F;  3S1M F;  3HKZ K;  4OIR E;  5C4J F;  4KMU E;  4A3J F;  4OIP E;  5D4C E;  3GTJ F;  3S2D F;  2JA7 F;  2WB1 I;  2O5I E;  3HOY F;  3M4O F;  4OIQ E;  3GTP F;  2E2H F;  3S14 F;  4KN7 E;  4Y7N F;  3HOZ F;  4G7Z E;  4X6A F;  2BE5 E;  3S15 F;  4A3D F;  3S2H F;  4A3B F;  3I4N F;  2JA8 F;  1I3Q F;  1TWC F;  4YFN E;  1SMY E;  2R93 F;  3H0G F;  1YNN K;  5C4X F;  1TWG F;  4MEY E;  3M3Y F;  3S1N F;  3HOW F;  4C3J F;  2JA6 F;  3GTK F;  1IW7 E;  5C3E F;  5IYC F;  4XLN E;  3H3V G;  4YFK E;  3HOV F;  3S17 F;  5BYH E;  2CW0 E;  1Y1W F;  3CQZ F;  4ZH4 E;  3HOX F;  1SFO F;  1TWA F;  4A3F F;  2VUM F;  5D4D E;  3S1R F;  2PPB E;  4AYB K;  5IP7 F;  3PO2 F;  2YU9 F;  2B63 F;  3FKI F;  4LLG E;  3GTL F;  4YG2 E;  5E18 E;  5FJ8 F;  1TWH F;  5C44 F;  4LK0 E;  1TWF F;  5M5X F;  5FLM F;  3S1Q F;  2E2I F;  4LJZ E;  3WOD E;  5D4E E;  1HQM E;  4YFX E;  3HOU F;  2KRX A;  5IP9 F;  4Q4Z E;  2E2J F;  4LK1 E;  4BBS F;  4QIW K;  5IPL E;  4A3K F;  3EQL E;  2NVQ F;  1I6H F;  2A6E E;  3GTG F;  4OIO E;  3I4M F;  2O5J E;  1QKL A;  5M3F F;  4BY7 F;  1I6V E;  5TMF E;  2WAQ K;  4A3I F;  4A3L F;  2NVX F;  4Y52 F;  2Y0S I;  4MQ9 E;  4XSZ E;  1K83 F;  2A6H E;  4Q5S E;  4A3M F;  3RZO F;  4BY1 F;  1YNJ K;  4BBR F;  3DXJ E;  4A3G F;  5M3M F;  2PMZ K;  5M5W F;  4A3E F;  4MEX E;  3S16 F;  1Y1V F;  4JK1 E;  4XLP E;  4KN4 E;  4A93 F;  2NVY F;  3GTM F;  4C3H F;  5M5Y F;  4G7H E;  4C3I F;  3PO3 F;  1WCM F;  4G7O E;  2R92 F;  2A69 E;  1R9T F;  5TMC E;  3K7A F;  4XSX E;  2JA5 F;  2R7Z F;  5IYB F;  2NVT F;  1I50 F; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...