5ADQB

Crystal structure of human tankyrase 2 in complex with jw55
Total Genus 1
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
1
sequence length
46
structure length
46
Chain Sequence
AHSPPGHHSVTGRPSVNGLALAEYVIYRGEQAYPEYLITYQIMRPE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Development and Structural Analysis of Adenosine Site Binding Tankyrase Inhibitors.
pubmed doi rcsb
molecule keywords TANKYRASE-2
molecule tags Transferase
source organism Homo sapiens
total genus 1
structure length 46
sequence length 46
ec nomenclature ec 2.4.2.30: NAD(+) ADP-ribosyltransferase.
pdb deposition date 2015-08-24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1620.50 Alpha Beta 3-Layer(aba) Sandwich YefM-like fold YefM-like fold 5adqB00
4L10C 4HLFC 4L0BC 4HLMC 5C5RC 4HKKB 4HKIC 4HL5C 4UI5C 4UVPB 4L2KC 5ADTB 5ADRB 4L0IC 4UI8C 4KZLC 4L0SC 4UI4C 4L2GC 5FPFC 4UI6C 4UI7C 4L33C 4L31C 4KZQC 4HKNC 4L0VC 4L32C 5ADQB 4HMHC 4HLGC 4KZUC 4HLHC 4UI3C 5C5PC 5C5QC 5ADSB 4L0TC 4L2FC 4L34C 4L09C 4HLKC
chains in the Genus database with same CATH superfamily
2ODKA 4L10C 4HLFC 3HRYA 4L0BC 3CTOA 2A6QA 4HLMC 5C5RC 3OEIE 4ZM2A 4HKKB 4HKIC 4HL5C 4UI5C 4UVPB 4ZM0A 4L2KC 3HJ6A 5ADTB 5ADRB 4L0IC 3K6QA 4UI8C 4KZLC 4L0SC 3K33B 2ZIXB 4UI4C 4L2GC 5FPFC 4UI6C 4UI7C 4L33C 4L31C 3OEIA 4KZQC 4HKNC 4L0VC 4L32C 5ADQB 4HLHC 4HLGC 4HMHC 4KZUC 4UI3C 5C5PC 5C5QC 4L34C 4ZLXA 3HS2A 3KH2E 5ADSB 3D55A 4L0TC 4L2FC 3G5OA 4L09C 4HLKC
chains in the Genus database with same CATH topology
4L10C 4HLFC 4L0BC 4HLMC 5C5RC 4HKKB 4HKIC 4HL5C 4UI5C 4UVPB 4L2KC 3HJ6A 5ADTB 5ADRB 4L0IC 4UI8C 4KZLC 4L0SC 2ZIXB 4UI4C 4L2GC 5FPFC 4UI6C 4UI7C 4L33C 4L31C 4KZQC 4HKNC 4L0VC 4L32C 5ADQB 4HMHC 4HLGC 4KZUC 4HLHC 4UI3C 5C5PC 5C5QC 5ADSB 4L0TC 4L2FC 4L34C 4L09C 4HLKC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4L10 C;  4HLF C;  4L0B C;  4HLM C;  5C5R C;  4HKK B;  4HKI C;  4HL5 C;  4UI5 C;  4UVP B;  4L2K C;  5ADT B;  5ADR B;  4L0I C;  4UI8 C;  4KZL C;  4L0S C;  4UI4 C;  4L2G C;  5FPF C;  4UI6 C;  4UI7 C;  4L33 C;  4L31 C;  4KZQ C;  4HKN C;  4L0V C;  4L32 C;  5ADQ B;  4HMH C;  4HLG C;  4KZU C;  4HLH C;  4UI3 C;  5C5P C;  5C5Q C;  5ADS B;  4L0T C;  4L2F C;  4L34 C;  4L09 C;  4HLK C; 
#chains in the Genus database with same CATH topology
 2ODK A;  4L10 C;  4HLF C;  3HRY A;  4L0B C;  3CTO A;  2A6Q A;  4HLM C;  5C5R C;  3OEI E;  4ZM2 A;  4HKK B;  4HKI C;  4HL5 C;  4UI5 C;  4UVP B;  4ZM0 A;  4L2K C;  3HJ6 A;  5ADT B;  5ADR B;  4L0I C;  3K6Q A;  4UI8 C;  4KZL C;  4L0S C;  3K33 B;  2ZIX B;  4UI4 C;  4L2G C;  5FPF C;  4UI6 C;  4UI7 C;  4L33 C;  4L31 C;  3OEI A;  4KZQ C;  4HKN C;  4L0V C;  4L32 C;  5ADQ B;  4HLH C;  4HLG C;  4HMH C;  4KZU C;  4UI3 C;  5C5P C;  5C5Q C;  4L34 C;  4ZLX A;  3HS2 A;  3KH2 E;  5ADS B;  3D55 A;  4L0T C;  4L2F C;  3G5O A;  4L09 C;  4HLK C; 
#chains in the Genus database with same CATH homology
 4L10 C;  4HLF C;  4L0B C;  4HLM C;  5C5R C;  4HKK B;  4HKI C;  4HL5 C;  4UI5 C;  4UVP B;  4L2K C;  3HJ6 A;  5ADT B;  5ADR B;  4L0I C;  4UI8 C;  4KZL C;  4L0S C;  2ZIX B;  4UI4 C;  4L2G C;  5FPF C;  4UI6 C;  4UI7 C;  4L33 C;  4L31 C;  4KZQ C;  4HKN C;  4L0V C;  4L32 C;  5ADQ B;  4HMH C;  4HLG C;  4KZU C;  4HLH C;  4UI3 C;  5C5P C;  5C5Q C;  5ADS B;  4L0T C;  4L2F C;  4L34 C;  4L09 C;  4HLK C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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