5ADQB

Crystal structure of human tankyrase 2 in complex with jw55
Total Genus 1
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
1
sequence length
46
structure length
46
Chain Sequence
AHSPPGHHSVTGRPSVNGLALAEYVIYRGEQAYPEYLITYQIMRPE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Development and Structural Analysis of Adenosine Site Binding Tankyrase Inhibitors.
pubmed doi rcsb
molecule keywords TANKYRASE-2
molecule tags Transferase
source organism Homo sapiens
total genus 1
structure length 46
sequence length 46
ec nomenclature ec 2.4.2.30: NAD(+) ADP-ribosyltransferase.
pdb deposition date 2015-08-24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1620.50 Alpha Beta 3-Layer(aba) Sandwich YefM-like fold YefM-like fold 5adqB00
5C5PC 5ADQB 5ADRB 4HKIC 4L32C 4HMHC 4KZUC 4HLFC 4UI7C 4L10C 4KZQC 4KZLC 4L09C 4HLKC 4UI3C 4UI6C 4L0IC 4UVPB 5ADTB 4UI8C 4HLHC 4HLMC 4HKKB 4HLGC 4L0BC 4L0VC 5C5RC 4HL5C 4L34C 4UI5C 4L0TC 4L0SC 4HKNC 5FPFC 4L2KC 4L31C 4L2FC 4UI4C 4L2GC 5C5QC 5ADSB 4L33C
chains in the Genus database with same CATH superfamily
5C5PC 3G5OA 3K33B 3KH2E 5ADRB 4HKIC 3OEIA 4ZM2A 5ADQB 4L32C 4HMHC 4KZUC 4HLFC 4UI7C 4L10C 4KZQC 4ZLXA 4KZLC 4L09C 4HLKC 4UI3C 4UI6C 4L0IC 4UVPB 5ADTB 3OEIE 4UI8C 4HLHC 4HLMC 3K6QA 3HRYA 4HKKB 4ZM0A 4HLGC 4L0BC 4L0VC 5C5RC 4HL5C 2A6QA 3HS2A 3CTOA 5ADSB 2ODKA 4L34C 4UI5C 4L0TC 4L0SC 4HKNC 5FPFC 4L2KC 3D55A 4L31C 4L2FC 2ZIXB 4UI4C 4L2GC 5C5QC 3HJ6A 4L33C
chains in the Genus database with same CATH topology
5C5PC 5ADQB 5ADRB 4HKIC 4L32C 4HMHC 4KZUC 4HLFC 4UI7C 4L10C 4KZQC 4KZLC 4L09C 4HLKC 4UI3C 4UI6C 4L0IC 4UVPB 5ADTB 4UI8C 4HLHC 4HLMC 4HKKB 4HLGC 4L0BC 4L0VC 5C5RC 4HL5C 5ADSB 4L34C 4UI5C 4L0TC 4L0SC 4HKNC 5FPFC 4L2KC 4L31C 4L2FC 2ZIXB 4UI4C 4L2GC 5C5QC 3HJ6A 4L33C
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5C5P C;  5ADQ B;  5ADR B;  4HKI C;  4L32 C;  4HMH C;  4KZU C;  4HLF C;  4UI7 C;  4L10 C;  4KZQ C;  4KZL C;  4L09 C;  4HLK C;  4UI3 C;  4UI6 C;  4L0I C;  4UVP B;  5ADT B;  4UI8 C;  4HLH C;  4HLM C;  4HKK B;  4HLG C;  4L0B C;  4L0V C;  5C5R C;  4HL5 C;  4L34 C;  4UI5 C;  4L0T C;  4L0S C;  4HKN C;  5FPF C;  4L2K C;  4L31 C;  4L2F C;  4UI4 C;  4L2G C;  5C5Q C;  5ADS B;  4L33 C; 
#chains in the Genus database with same CATH topology
 5C5P C;  3G5O A;  3K33 B;  3KH2 E;  5ADR B;  4HKI C;  3OEI A;  4ZM2 A;  5ADQ B;  4L32 C;  4HMH C;  4KZU C;  4HLF C;  4UI7 C;  4L10 C;  4KZQ C;  4ZLX A;  4KZL C;  4L09 C;  4HLK C;  4UI3 C;  4UI6 C;  4L0I C;  4UVP B;  5ADT B;  3OEI E;  4UI8 C;  4HLH C;  4HLM C;  3K6Q A;  3HRY A;  4HKK B;  4ZM0 A;  4HLG C;  4L0B C;  4L0V C;  5C5R C;  4HL5 C;  2A6Q A;  3HS2 A;  3CTO A;  5ADS B;  2ODK A;  4L34 C;  4UI5 C;  4L0T C;  4L0S C;  4HKN C;  5FPF C;  4L2K C;  3D55 A;  4L31 C;  4L2F C;  2ZIX B;  4UI4 C;  4L2G C;  5C5Q C;  3HJ6 A;  4L33 C; 
#chains in the Genus database with same CATH homology
 5C5P C;  5ADQ B;  5ADR B;  4HKI C;  4L32 C;  4HMH C;  4KZU C;  4HLF C;  4UI7 C;  4L10 C;  4KZQ C;  4KZL C;  4L09 C;  4HLK C;  4UI3 C;  4UI6 C;  4L0I C;  4UVP B;  5ADT B;  4UI8 C;  4HLH C;  4HLM C;  4HKK B;  4HLG C;  4L0B C;  4L0V C;  5C5R C;  4HL5 C;  5ADS B;  4L34 C;  4UI5 C;  4L0T C;  4L0S C;  4HKN C;  5FPF C;  4L2K C;  4L31 C;  4L2F C;  2ZIX B;  4UI4 C;  4L2G C;  5C5Q C;  3HJ6 A;  4L33 C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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