5ADSB

Crystal structure of human tankyrase 2 in complex with od39
Total Genus 1
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
1
sequence length
46
structure length
46
Chain Sequence
AHSPPGHHSVTGRPSVNGLALAEYVIYRGEQAYPEYLITYQIMRPE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Development and Structural Analysis of Adenosine Site Binding Tankyrase Inhibitors.
pubmed doi rcsb
molecule tags Transferase
source organism Homo sapiens
molecule keywords TANKYRASE-2
total genus 1
structure length 46
sequence length 46
ec nomenclature ec 2.4.2.30: NAD(+) ADP-ribosyltransferase.
pdb deposition date 2015-08-24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1620.50 Alpha Beta 3-Layer(aba) Sandwich YefM-like fold YefM-like fold 5adsB00
4L33C 4L32C 4UVPB 4L2FC 4L2KC 4UI3C 5C5PC 4KZQC 4HKNC 4HLKC 4L0IC 4HLGC 4KZLC 4HLMC 4KZUC 4L31C 4HMHC 5C5QC 4HL5C 4UI4C 4L0SC 4UI8C 5FPFC 4UI7C 5ADQB 4HKIC 4L10C 4L0BC 4L34C 4HLFC 4L0VC 4L2GC 4L09C 4UI5C 5C5RC 5ADSB 5ADTB 4HKKB 4L0TC 4HLHC 5ADRB 4UI6C
chains in the Genus database with same CATH superfamily
3K33B 3K6QA 4L33C 3OEIA 4L32C 3KH2E 4UVPB 4L2FC 4L2KC 4UI3C 5C5PC 4ZM2A 2ZIXB 3CTOA 4KZQC 3G5OA 4HLKC 4HKNC 2ODKA 4L0IC 3HJ6A 2A6QA 4HLGC 4HLMC 4KZLC 4KZUC 3OEIE 3HRYA 3HS2A 4L31C 4HMHC 5C5QC 4HL5C 4UI4C 4L0SC 4UI8C 5FPFC 4UI7C 5ADQB 4HKIC 4L10C 4L0BC 4L34C 4HLFC 4L0VC 4L2GC 4L09C 4UI5C 5C5RC 5ADSB 3D55A 5ADTB 4HKKB 4L0TC 4HLHC 4ZM0A 4ZLXA 5ADRB 4UI6C
chains in the Genus database with same CATH topology
4L33C 4L32C 4UVPB 4L2FC 4L2KC 4UI3C 5C5PC 2ZIXB 4KZQC 4HKNC 4HLKC 4L0IC 4HLGC 3HJ6A 4HLMC 4KZLC 4KZUC 4L31C 4HMHC 5C5QC 4HL5C 4UI4C 4L0SC 4UI8C 5FPFC 4UI7C 5ADQB 4HKIC 4L10C 4L0BC 4L34C 4HLFC 4L0VC 4L2GC 4L09C 4UI5C 5C5RC 5ADSB 5ADTB 4HKKB 4L0TC 4HLHC 5ADRB 4UI6C
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4L33 C;  4L32 C;  4UVP B;  4L2F C;  4L2K C;  4UI3 C;  5C5P C;  4KZQ C;  4HKN C;  4HLK C;  4L0I C;  4HLG C;  4KZL C;  4HLM C;  4KZU C;  4L31 C;  4HMH C;  5C5Q C;  4HL5 C;  4UI4 C;  4L0S C;  4UI8 C;  5FPF C;  4UI7 C;  5ADQ B;  4HKI C;  4L10 C;  4L0B C;  4L34 C;  4HLF C;  4L0V C;  4L2G C;  4L09 C;  4UI5 C;  5C5R C;  5ADS B;  5ADT B;  4HKK B;  4L0T C;  4HLH C;  5ADR B;  4UI6 C; 
#chains in the Genus database with same CATH topology
 3K33 B;  3K6Q A;  4L33 C;  3OEI A;  4L32 C;  3KH2 E;  4UVP B;  4L2F C;  4L2K C;  4UI3 C;  5C5P C;  4ZM2 A;  2ZIX B;  3CTO A;  4KZQ C;  3G5O A;  4HLK C;  4HKN C;  2ODK A;  4L0I C;  3HJ6 A;  2A6Q A;  4HLG C;  4HLM C;  4KZL C;  4KZU C;  3OEI E;  3HRY A;  3HS2 A;  4L31 C;  4HMH C;  5C5Q C;  4HL5 C;  4UI4 C;  4L0S C;  4UI8 C;  5FPF C;  4UI7 C;  5ADQ B;  4HKI C;  4L10 C;  4L0B C;  4L34 C;  4HLF C;  4L0V C;  4L2G C;  4L09 C;  4UI5 C;  5C5R C;  5ADS B;  3D55 A;  5ADT B;  4HKK B;  4L0T C;  4HLH C;  4ZM0 A;  4ZLX A;  5ADR B;  4UI6 C; 
#chains in the Genus database with same CATH homology
 4L33 C;  4L32 C;  4UVP B;  4L2F C;  4L2K C;  4UI3 C;  5C5P C;  2ZIX B;  4KZQ C;  4HKN C;  4HLK C;  4L0I C;  4HLG C;  3HJ6 A;  4HLM C;  4KZL C;  4KZU C;  4L31 C;  4HMH C;  5C5Q C;  4HL5 C;  4UI4 C;  4L0S C;  4UI8 C;  5FPF C;  4UI7 C;  5ADQ B;  4HKI C;  4L10 C;  4L0B C;  4L34 C;  4HLF C;  4L0V C;  4L2G C;  4L09 C;  4UI5 C;  5C5R C;  5ADS B;  5ADT B;  4HKK B;  4L0T C;  4HLH C;  5ADR B;  4UI6 C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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