5ADSB

Crystal structure of human tankyrase 2 in complex with od39
Total Genus 1
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
1
sequence length
46
structure length
46
Chain Sequence
AHSPPGHHSVTGRPSVNGLALAEYVIYRGEQAYPEYLITYQIMRPE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Development and Structural Analysis of Adenosine Site Binding Tankyrase Inhibitors.
pubmed doi rcsb
molecule keywords TANKYRASE-2
molecule tags Transferase
source organism Homo sapiens
total genus 1
structure length 46
sequence length 46
ec nomenclature ec 2.4.2.30: NAD(+) ADP-ribosyltransferase.
pdb deposition date 2015-08-24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1620.50 Alpha Beta 3-Layer(aba) Sandwich YefM-like fold YefM-like fold 5adsB00
4L2GC 5ADTB 4UI5C 4L31C 4L33C 4UI3C 4KZQC 5C5QC 4L0SC 4HMHC 4UI6C 5FPFC 4HLMC 5C5PC 4HLHC 4HKIC 5ADQB 4HLGC 4L2FC 4UI8C 5C5RC 4HKNC 5ADRB 4L10C 5ADSB 4UVPB 4HLFC 4UI4C 4L0TC 4KZLC 4UI7C 4HKKB 4L34C 4KZUC 4L0BC 4L32C 4L0VC 4L0IC 4HLKC 4L2KC 4HL5C 4L09C
chains in the Genus database with same CATH superfamily
3K6QA 4L2GC 5ADTB 4UI5C 4L31C 2A6QA 3HJ6A 4L33C 4UI3C 4KZQC 5C5QC 4L0SC 4HMHC 3HRYA 3G5OA 4UI6C 3OEIE 5FPFC 4HLMC 5C5PC 4HLHC 4HKIC 5ADQB 4HLGC 4L2FC 4UI8C 5C5RC 4HKNC 5ADRB 4ZM2A 4L10C 5ADSB 4UVPB 4HLFC 3OEIA 4UI4C 4L0TC 4ZLXA 4KZLC 4UI7C 4HKKB 4L34C 3D55A 4KZUC 4L0BC 2ZIXB 4L32C 4L0VC 3K33B 4L0IC 3HS2A 2ODKA 4HLKC 4L2KC 4HL5C 4ZM0A 3CTOA 4L09C 3KH2E
chains in the Genus database with same CATH topology
4L2GC 5ADTB 4UI5C 4L31C 4L33C 3HJ6A 4UI3C 4KZQC 5C5QC 4L0SC 4HMHC 4UI6C 5FPFC 4HLMC 5C5PC 4HLHC 4HKIC 5ADQB 4HLGC 4L2FC 4UI8C 5C5RC 4HKNC 5ADRB 4L10C 5ADSB 4UVPB 4HLFC 4UI4C 4L0TC 4KZLC 4UI7C 4HKKB 4L34C 4KZUC 4L0BC 2ZIXB 4L32C 4L0VC 4L0IC 4HLKC 4L2KC 4HL5C 4L09C
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4L2G C;  5ADT B;  4UI5 C;  4L31 C;  4L33 C;  4UI3 C;  4KZQ C;  5C5Q C;  4L0S C;  4HMH C;  4UI6 C;  5FPF C;  4HLM C;  5C5P C;  4HLH C;  4HKI C;  5ADQ B;  4HLG C;  4L2F C;  4UI8 C;  5C5R C;  4HKN C;  5ADR B;  4L10 C;  5ADS B;  4UVP B;  4HLF C;  4UI4 C;  4L0T C;  4KZL C;  4UI7 C;  4HKK B;  4L34 C;  4KZU C;  4L0B C;  4L32 C;  4L0V C;  4L0I C;  4HLK C;  4L2K C;  4HL5 C;  4L09 C; 
#chains in the Genus database with same CATH topology
 3K6Q A;  4L2G C;  5ADT B;  4UI5 C;  4L31 C;  2A6Q A;  3HJ6 A;  4L33 C;  4UI3 C;  4KZQ C;  5C5Q C;  4L0S C;  4HMH C;  3HRY A;  3G5O A;  4UI6 C;  3OEI E;  5FPF C;  4HLM C;  5C5P C;  4HLH C;  4HKI C;  5ADQ B;  4HLG C;  4L2F C;  4UI8 C;  5C5R C;  4HKN C;  5ADR B;  4ZM2 A;  4L10 C;  5ADS B;  4UVP B;  4HLF C;  3OEI A;  4UI4 C;  4L0T C;  4ZLX A;  4KZL C;  4UI7 C;  4HKK B;  4L34 C;  3D55 A;  4KZU C;  4L0B C;  2ZIX B;  4L32 C;  4L0V C;  3K33 B;  4L0I C;  3HS2 A;  2ODK A;  4HLK C;  4L2K C;  4HL5 C;  4ZM0 A;  3CTO A;  4L09 C;  3KH2 E; 
#chains in the Genus database with same CATH homology
 4L2G C;  5ADT B;  4UI5 C;  4L31 C;  4L33 C;  3HJ6 A;  4UI3 C;  4KZQ C;  5C5Q C;  4L0S C;  4HMH C;  4UI6 C;  5FPF C;  4HLM C;  5C5P C;  4HLH C;  4HKI C;  5ADQ B;  4HLG C;  4L2F C;  4UI8 C;  5C5R C;  4HKN C;  5ADR B;  4L10 C;  5ADS B;  4UVP B;  4HLF C;  4UI4 C;  4L0T C;  4KZL C;  4UI7 C;  4HKK B;  4L34 C;  4KZU C;  4L0B C;  2ZIX B;  4L32 C;  4L0V C;  4L0I C;  4HLK C;  4L2K C;  4HL5 C;  4L09 C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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