5BP2 | Genus

Total Genus 71

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	71
sequence length	285
structure length	285
Chain Sequence	PSVSVHPLLGSHVVLPQEPEEHLWQGDVGTEAHPWLSDHRVHQVAVLPGAAYCEMALAAVTPVLGDTGEVHDLKFHDMLLLDDATPVWVSAAVTAPGTAEFGVETHQSGDRTQRATAVLRGDVDAERPAAHSIDALLAAHPNRVDGDELRAGFGTVGIGHGAAFAGLSEAYVATAAEPTVVAAVALPGPLRSGQRGYTVHPALLDACFQSVIAHPEVQNIASGMLLPLGVRRLRAYGSTRNVRYCLSRIVKADSFGVEADLELLDADGTVLLSAMGLQLGTGNSD

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

molecule tags	Lyase
source organism	Mycobacterium smegmatis
publication title	Mycocerosic acid synthase exemplifies the architecture of reducing polyketide synthases. pubmed doi rcsb
molecule keywords	Mycocerosic acid synthase-like polyketide synthase
total genus	71
structure length	285
sequence length	285
chains with identical sequence	B, C, D
ec nomenclature	ec 2.3.1.-:
pdb deposition date	2015-05-27

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF14765	PS-DH	Polyketide synthase dehydratase

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.10.129.110	Alpha Beta	Roll	Thiol Ester Dehydrase; Chain A	Thiol Ester Dehydrase; Chain A	5bp2A00

4KC5A 5BP3A 3KG9A 3HRQA 3HRRA 3KG6A 4U3VA 2VZ8A 3KG7A 5KKUA 5E1VA 3EL6A 2VZ9A 4OOCA 5BP2A 4LN9A
chains in the Genus database with same CATH superfamily

4ZRFA 4KC5A 5BYUA 2HX5A 3KVZA 1IQ6A 3TEAA 3D04A 2OAFA 3ZH7A 1VH9A 3Q62A 2VZ9A 4RLJA 1J1YA 3DOYA 3ZH6A 3LBBA 4B0CA 4HZNA 4HZOA 3D6XA 2PRXA 4I45A 4K4BA 1T82A 1WLUA 3BNVA 4MOBA 5T06A 5BUYA 2CWZA 3AZAA 4RLWA 4CL6A 3DP1A 4I4JA 4QD9A 4R9ZA 2O6TA 3P2SA 5SZYA 2B6EA 2VKZG 4E3EA 1MKAA 1ZKIA 2XFLA 2O6UA 1Q4UA 3KUWA 1ZHGA 4RLUB 2F0XA 3R3BA 4MZQA 4K00A 4QD7A 4K49A 1VH5A 2QQ2A 4K4AA 2PFCA 3B7KA 3CK1A 5SZZA 3LZ7A 3P2QA 3LW3A 5BUXA 5HZ4A 2GLPA 5SZVA 5DIOA 4A12A 4I83A 5KL9A 4U3VA 3EXZA 4RLTA 1S5UA 2DSLA 3AZ8A 2QWZA 3CJYA 3LBEA 4FQ9A 4W78B 5EGKA 5HD6A 4QDAA 4MOCA 3KVIA 5HWFA 1Q4SA 3KG9A 4NCPA 3HRRA 5CPGA 3AZ9A 3CF9A 3QY3A 5T07A 4WNBA 3BJKA 3CF8A 3LWGA 4GAHA 3WEWA 2HLJA 3NWZA 3B18A 4ORDA 4ZV3A 5DM5A 2Q78A 3ED0A 2OV9A 3HRQA 2UV8G 4QD8A 2CYEA 2VZ8A 1YOCA 3KVUA 3HDUA 2FS2A 2F41A 2H4UA 3KG8A 4RLJB 3R87A 5HMBA 5HMCA 5BUWA 1U1ZA 3K67A 3KW1A 2GLLA 2OIWA 3GEKA 5E1VA 4KEHA 4H4GA 2XEMA 2C2IA 3HM0A 4RLWB 4GAKA 1Y7UA 3R32A 4RLUA 5EGLA 5F6RA 3B7JA 1Z6BA 4I82A 3RD7A 4B0JA 1TBUA 3R3FA 1LO7A 2BI0A 3DP0A 5EO4A 3U0AA 1S9CA 3E1EA 4K4CA 4QFWA 2NUJA 1PN2A 3DKZA 3S4KA 4HZPA 1Q6WA 1SC0A 2PZHA 2V1OA 3FRNA 3R34A 2EGRA 1MKBA 1LO8A 2EGJA 2O6BA 2Q2BA 3ESIA 3R37A 1PN4A 4RV2A 2GVHA 2ESSA 3R3CA 4W78A 5EO2A 3LMBA 3KH8A 1SH8A 3KHPA 4ZJBA 4M20A 3DP3A 4AE7A 3F1TA 3KV8A 5BP2A 4RLTB 3E8PA 3P3IA 5EGJA 4ZRBA 3ZH7B 4AE8A 5BP3A 3IR3A 3AZBA 1VI8A 1C8UA 4A0XA 1YLIA 3S6PA 3EL6A 2QQPA 2OWNA 2GLVA 4K02A 4OOBA 1BVQA 4WNBB 2EGIA 2EISA 3R35A 5EP5A 2GLMA 3D6LA 4IENA 3BBJA 3QOOA 3KX7A 4XY6A 5SZUA 5T02A 4B8UA 1VPMA 2FUJA 1WN3A 2GF6A 3KV7A 4LN9A 3E29A 3R36A 2O5UA 4A0YA 3F5OA 4K4DA 3KG7A 3ZH5A 4MTUA 3P2RA 2F3XA 4QDBA 1LO9A 4ZW0A 3RQBA 3DOZA 1Z54A 1OHFA 2CY9A 3P3FA 4RMMA 4B0BA 2AV9A 3KUVA 4B0IA 3KG6A 1PSUA 1IXLA 1NJKA 3DP2A 3R3AA 4FFUA 1Q4TA 4A0ZA 1WLVA 4R4UA 4OOCA 3SPSA 2PIMA 3R3DA 3OMLA 4XY5A 1WM6A 4YBVA 2OKIA 1SBKA 3KX8A 2W3XA 5KKUA 2B3MA 2OKHA 3HMJG 2HBOA 4RV2B
chains in the Genus database with same CATH topology

4KC5A 4U3VA 3U0AA 3BBJA 3ZH7A 3ZH6A 3CJYA 2VZ9A 4QFWA 4LN9A 3KG9A 3HRRA 3KG7A 3ZH5A 3FRNA 4R9ZA 3RQBA 3B18A 1OHFA 2VKZG 3HRQA 2UV8G 3KG6A 2VZ8A 4R4UA 5BP2A 4OOCA 3KG8A 3ZH7B 5BP3A 2PFCA 5KKUA 5E1VA 3S6PA 3EL6A 2QQPA 3HMJG 3RD7A
chains in the Genus database with same CATH homology

#chains in the Genus database with same CATH superfamily
 4KC5 A;  5BP3 A;  3KG9 A;  3HRQ A;  3HRR A;  3KG6 A;  4U3V A;  2VZ8 A;  3KG7 A;  5KKU A;  5E1V A;  3EL6 A;  2VZ9 A;  4OOC A;  5BP2 A;  4LN9 A; 
#chains in the Genus database with same CATH topology
 4ZRF A;  4KC5 A;  5BYU A;  2HX5 A;  3KVZ A;  1IQ6 A;  3TEA A;  3D04 A;  2OAF A;  3ZH7 A;  1VH9 A;  3Q62 A;  2VZ9 A;  4RLJ A;  1J1Y A;  3DOY A;  3ZH6 A;  3LBB A;  4B0C A;  4HZN A;  4HZO A;  3D6X A;  2PRX A;  4I45 A;  4K4B A;  1T82 A;  1WLU A;  3BNV A;  4MOB A;  5T06 A;  5BUY A;  2CWZ A;  3AZA A;  4RLW A;  4CL6 A;  3DP1 A;  4I4J A;  4QD9 A;  4R9Z A;  2O6T A;  3P2S A;  5SZY A;  2B6E A;  2VKZ G;  4E3E A;  1MKA A;  1ZKI A;  2XFL A;  2O6U A;  1Q4U A;  3KUW A;  1ZHG A;  4RLU B;  2F0X A;  3R3B A;  4MZQ A;  4K00 A;  4QD7 A;  4K49 A;  1VH5 A;  2QQ2 A;  4K4A A;  2PFC A;  3B7K A;  3CK1 A;  5SZZ A;  3LZ7 A;  3P2Q A;  3LW3 A;  5BUX A;  5HZ4 A;  2GLP A;  5SZV A;  5DIO A;  4A12 A;  4I83 A;  5KL9 A;  4U3V A;  3EXZ A;  4RLT A;  1S5U A;  2DSL A;  3AZ8 A;  2QWZ A;  3CJY A;  3LBE A;  4FQ9 A;  4W78 B;  5EGK A;  5HD6 A;  4QDA A;  4MOC A;  3KVI A;  5HWF A;  1Q4S A;  3KG9 A;  4NCP A;  3HRR A;  5CPG A;  3AZ9 A;  3CF9 A;  3QY3 A;  5T07 A;  4WNB A;  3BJK A;  3CF8 A;  3LWG A;  4GAH A;  3WEW A;  2HLJ A;  3NWZ A;  3B18 A;  4ORD A;  4ZV3 A;  5DM5 A;  2Q78 A;  3ED0 A;  2OV9 A;  3HRQ A;  2UV8 G;  4QD8 A;  2CYE A;  2VZ8 A;  1YOC A;  3KVU A;  3HDU A;  2FS2 A;  2F41 A;  2H4U A;  3KG8 A;  4RLJ B;  3R87 A;  5HMB A;  5HMC A;  5BUW A;  1U1Z A;  3K67 A;  3KW1 A;  2GLL A;  2OIW A;  3GEK A;  5E1V A;  4KEH A;  4H4G A;  2XEM A;  2C2I A;  3HM0 A;  4RLW B;  4GAK A;  1Y7U A;  3R32 A;  4RLU A;  5EGL A;  5F6R A;  3B7J A;  1Z6B A;  4I82 A;  3RD7 A;  4B0J A;  1TBU A;  3R3F A;  1LO7 A;  2BI0 A;  3DP0 A;  5EO4 A;  3U0A A;  1S9C A;  3E1E A;  4K4C A;  4QFW A;  2NUJ A;  1PN2 A;  3DKZ A;  3S4K A;  4HZP A;  1Q6W A;  1SC0 A;  2PZH A;  2V1O A;  3FRN A;  3R34 A;  2EGR A;  1MKB A;  1LO8 A;  2EGJ A;  2O6B A;  2Q2B A;  3ESI A;  3R37 A;  1PN4 A;  4RV2 A;  2GVH A;  2ESS A;  3R3C A;  4W78 A;  5EO2 A;  3LMB A;  3KH8 A;  1SH8 A;  3KHP A;  4ZJB A;  4M20 A;  3DP3 A;  4AE7 A;  3F1T A;  3KV8 A;  5BP2 A;  4RLT B;  3E8P A;  3P3I A;  5EGJ A;  4ZRB A;  3ZH7 B;  4AE8 A;  5BP3 A;  3IR3 A;  3AZB A;  1VI8 A;  1C8U A;  4A0X A;  1YLI A;  3S6P A;  3EL6 A;  2QQP A;  2OWN A;  2GLV A;  4K02 A;  4OOB A;  1BVQ A;  4WNB B;  2EGI A;  2EIS A;  3R35 A;  5EP5 A;  2GLM A;  3D6L A;  4IEN A;  3BBJ A;  3QOO A;  3KX7 A;  4XY6 A;  5SZU A;  5T02 A;  4B8U A;  1VPM A;  2FUJ A;  1WN3 A;  2GF6 A;  3KV7 A;  4LN9 A;  3E29 A;  3R36 A;  2O5U A;  4A0Y A;  3F5O A;  4K4D A;  3KG7 A;  3ZH5 A;  4MTU A;  3P2R A;  2F3X A;  4QDB A;  1LO9 A;  4ZW0 A;  3RQB A;  3DOZ A;  1Z54 A;  1OHF A;  2CY9 A;  3P3F A;  4RMM A;  4B0B A;  2AV9 A;  3KUV A;  4B0I A;  3KG6 A;  1PSU A;  1IXL A;  1NJK A;  3DP2 A;  3R3A A;  4FFU A;  1Q4T A;  4A0Z A;  1WLV A;  4R4U A;  4OOC A;  3SPS A;  2PIM A;  3R3D A;  3OML A;  4XY5 A;  1WM6 A;  4YBV A;  2OKI A;  1SBK A;  3KX8 A;  2W3X A;  5KKU A;  2B3M A;  2OKH A;  3HMJ G;  2HBO A;  4RV2 B; 
#chains in the Genus database with same CATH homology
 4KC5 A;  4U3V A;  3U0A A;  3BBJ A;  3ZH7 A;  3ZH6 A;  3CJY A;  2VZ9 A;  4QFW A;  4LN9 A;  3KG9 A;  3HRR A;  3KG7 A;  3ZH5 A;  3FRN A;  4R9Z A;  3RQB A;  3B18 A;  1OHF A;  2VKZ G;  3HRQ A;  2UV8 G;  3KG6 A;  2VZ8 A;  4R4U A;  5BP2 A;  4OOC A;  3KG8 A;  3ZH7 B;  5BP3 A;  2PFC A;  5KKU A;  5E1V A;  3S6P A;  3EL6 A;  2QQP A;  3HMJ G;  3RD7 A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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5BP2A

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

pfam database annotations