5BYHE

Crystal structure of escherichia coli rna polymerase - sigma54 holoenzyme complex
Total Genus 20
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
20
sequence length
79
structure length
79
Chain Sequence
TVQDAVEKIGNRFDLVLVAARRARQMQVGGKDPLVPEENDKTTVIALREIEEGLINNQILDVRERQEQQEQEAAELQAV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase
source organism Escherichia coli
publication title TRANSCRIPTION. Structures of the RNA polymerase-sigma 54 reveal new and conserved regulatory strategies.
pubmed doi rcsb
molecule keywords DNA-directed RNA polymerase subunit alpha
total genus 20
structure length 79
sequence length 79
ec nomenclature ec 2.7.7.6: DNA-directed RNA polymerase.
pdb deposition date 2015-06-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF01192 RNA_pol_Rpb6 RNA polymerase Rpb6
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.940.10 Alpha Beta Alpha-Beta Complex Eukaryotic RPB6 RNA polymerase subunit Eukaryotic RPB6 RNA polymerase subunit 5byhE00
4A3EF 4C3IF 4YFNE 3DXJE 3S2HF 3PO3F 3M3YF 2JA8F 2NVXF 2JA7F 5M3FF 3RZOF 1I3QF 2JA6F 5M5XF 1SFOF 3S1RF 4YG2E 4XLPE 4G7HE 4A3FF 1Y1WF 4Q4ZE 3GTLF 2A6HE 3M4OF 5BYHE 5D4CE 3HOVF 5IP9F 1YNJK 4BY7F 3S17F 4C3JF 3CQZF 5IYDF 4KN7E 4C3HF 3S1MF 4X6AF 2E2IF 2WAQK 4A3GF 1I6HF 4LK0E 4OIQE 1YNNK 4Y7NF 3HOWF 3GTJF 4LK1E 1Y1VF 5E18E 3HOXF 2A68E 4KN4E 3RZDF 5TMFE 2PPBE 5IPLE 1HQME 4G7OE 2A6EE 2YU9F 2O5JE 4XSZE 5M5WF 4A3DF 1IW7E 5IYCF 5D4EE 1I50F 4A93F 1TWCF 4GZYE 4XSXE 2NVTF 3S1NF 5M3MF 3GTMF 3H0GF 3I4NF 3FKIF 4A3MF 3GTKF 5FJ8F 3HOYF 4AYBK 2R7ZF 5M5YF 2PMZK 4YFKE 4A3JF 3GTPF 4BY1F 4A3BF 1SMYE 4C2MF 2E2HF 4A3IF 2B63F 3HOUF 1I6VE 2CW0E 1TWFF 5C4XF 4KMUE 2WB1I 4BXXF 1K83F 2E2JF 1ZYRE 4Q5SE 4XLNE 3HKZK 2Y0SI 2NVQF 3GTOF 4LJZE 1TWHF 4BBSF 4LLGE 4OIRE 3GTGF 1R9TF 3K7AF 3S1QF 1TWGF 1TWAF 5C3EF 1QKLA 3WODE 4ZH4E 4OIOE 3GTQF 3S15F 5TMCE 1WCMF 4JK1E 3S2DF 5IYBF 2A69E 3S14F 4OIPE 3S16F 4OINE 5IP7F 2BE5E 4BBRF 2JA5F 5D4DE 4A3KF 3EQLE 4Y52F 4MQ9E 2R92F 2O5IE 4YFXE 4A3CF 2NVYF 4MEYE 3I4MF 4MEXE 3HOZF 4A3LF 5C44F 2VUMF 2R93F 5FLMF 4G7ZE 3H3VG 5E17E 5C4JF 3PO2F
chains in the Genus database with same CATH superfamily
2NVQE 2Y0SH 4C3IF 4YFNE 3DXJE 4A3EF 3GTOE 3S2HF 3PO3F 3M3YF 2JA8F 1DZFA 2NVXF 2JA7F 5M3FF 1R9TE 3K7AE 1I3QF 2JA6F 3RZOF 4A3CE 3S1QE 5M5XF 1TWAE 5C3EE 3HOZE 4A3LE 1SFOF 2VUME 3S1RF 4YG2E 5FLME 4XLPE 4G7HE 4A3FF 4Q4ZE 1Y1WF 2A6HE 3GTLF 5BYHE 5D4CE 3GTQE 3M4OF 3S15E 3HOVF 1WCME 1YNJK 5IP9F 4BY7F 3PO3E 3S2DE 2JA8E 3S17F 3S2HE 4C3JF 3CQZF 5IYDF 4KN7E 3S14E 4C3HF 2JA6E 4QIWH 3S1MF 4X6AF 2E2IF 2WAQK 5IP7E 4BBRE 1I6HF 4LK0E 4A3GF 4OIQE 3HOVE 1EIKA 4A3KE 1YNNK 4Y7NF 5IP9E 3GTJF 4LK1E 1Y1VF 3HOWF 4BY7E 5E18E 3HOXF 2A68E 4KN4E 4C3HE 3RZDF 4Y52E 5TMFE 4AYBH 2R92E 2PPBE 4X6AE 5IPLE 2PMZH 1HQME 4G7OE 2A6EE 2NVYE 2YU9F 1I6HE 2O5JE 4XSZE 5M5WF 3I4ME 4A3DF 4Y7NE 3GTJE 1IW7E 5C44E 5IYCF 5D4EE 2R93E 1I50F 3HOXE 4QIWK 5C4JE 3RZDE 3PO2E 4A3EE 1TWCF 4C3IE 4XSXE 2NVTF 4A93F 4GZYE 3M3YE 2NVXE 2JA7E 5M3MF 3GTMF 3S1NF 3H0GF 5M3FE 3I4NF 1I3QE 3RZOE 3FKIF 5M5WE 5M5XE 4A3MF 3HKZH 1SFOE 3GTKF 5FJ8F 3S1RE 1Y1WE 3HOYF 4AYBK 4A3FE 3GTLE 3M4OE 2R7ZF 5M5YF 2PMZK 4YFKE 4A3JF 3GTPF 4BY1F 3S17E 5IYDE 3CQZE 4C3JE 1SMYE 4C2MF 2E2HF 4A3BF 4A3IF 2B63F 3HOUF 3FKIE 1I6VE 2CW0E 1TWFF 3S1ME 5C4XF 2E2IE 4KMUE 2WB1I 5FJ8E 4BXXF 1K83F 2E2JF 4A3GE 1ZYRE 4Q5SE 2KRXA 3HOWE 1Y1VE 4A3BE 4XLNE 4C2ME 3HKZK 2Y0SI 2NVQF 3GTOF 4LJZE 1TWHF 4BBSF 4LLGE 4OIRE 3GTGF 1R9TF 4BXXE 3K7AF 2E2JE 2YU9E 3S1QF 1TWGF 4A3DE 1TWAF 5C3EF 1QKLA 3WODE 5IYCE 4ZH4E 1I50E 4OIOE 3GTQF 3S15F 5TMCE 2WAQH 3H3VF 4A93E 1TWCE 1WCMF 1TWHE 4JK1E 2NVTE 3S2DF 4BBSE 5IYBF 3S1NE 2A69E 5M3ME 3GTGE 3GTME 3H0GE 4OIPE 3I4NE 3S14F 3S16F 4OINE 1TWGE 4A3ME 3GTKE 3HOYE 5IP7F 2BE5E 2R7ZE 4BBRF 2JA5F 5M5YE 5D4DE 4A3KF 4A3JE 3EQLE 3GTPE 4BY1E 5IYBE 2E2HE 4Y52F 4A3IE 2B63E 3HOUE 4MQ9E 2R92F 3S16E 2O5IE 5C4XE 1TWFE 2WB1H 4YFXE 4A3CF 1K83E 2NVYF 4MEYE 2JA5E 3I4MF 4MEXE 3HOZF 4A3LF 5C44F 2VUMF 2R93F 5FLMF 4G7ZE 3H3VG 5E17E 5C4JF 3PO2F
chains in the Genus database with same CATH topology
4A3EF 4C3IF 4YFNE 3DXJE 3S2HF 3PO3F 3M3YF 2JA8F 2NVXF 2JA7F 5M3FF 3RZOF 1I3QF 2JA6F 5M5XF 1SFOF 3S1RF 4YG2E 4XLPE 4G7HE 4A3FF 1Y1WF 4Q4ZE 3GTLF 2A6HE 3M4OF 5BYHE 5D4CE 3HOVF 5IP9F 1YNJK 4BY7F 3S17F 4C3JF 3CQZF 5IYDF 4KN7E 4C3HF 3S1MF 4X6AF 2E2IF 2WAQK 4A3GF 1I6HF 4LK0E 4OIQE 1YNNK 4Y7NF 3HOWF 3GTJF 4LK1E 1Y1VF 5E18E 3HOXF 2A68E 4KN4E 3RZDF 5TMFE 2PPBE 5IPLE 1HQME 4G7OE 2A6EE 2YU9F 2O5JE 4XSZE 5M5WF 4A3DF 1IW7E 5IYCF 5D4EE 1I50F 4QIWK 4A93F 1TWCF 4GZYE 4XSXE 2NVTF 3S1NF 5M3MF 3GTMF 3H0GF 3I4NF 3FKIF 4A3MF 3GTKF 5FJ8F 3HOYF 4AYBK 2R7ZF 5M5YF 2PMZK 4YFKE 4A3JF 3GTPF 4BY1F 4A3BF 1SMYE 4C2MF 2E2HF 4A3IF 2B63F 3HOUF 1I6VE 2CW0E 1TWFF 5C4XF 4KMUE 2WB1I 4BXXF 1K83F 2E2JF 1ZYRE 4Q5SE 2KRXA 4XLNE 3HKZK 2Y0SI 2NVQF 3GTOF 4LJZE 1TWHF 4BBSF 4LLGE 4OIRE 3GTGF 1R9TF 3K7AF 3S1QF 1TWGF 1TWAF 5C3EF 1QKLA 3WODE 4ZH4E 4OIOE 3GTQF 3S15F 5TMCE 1WCMF 4JK1E 3S2DF 5IYBF 2A69E 3S14F 4OIPE 3S16F 4OINE 5IP7F 2BE5E 4BBRF 2JA5F 5D4DE 4A3KF 3EQLE 4Y52F 4MQ9E 2R92F 2O5IE 4YFXE 4A3CF 2NVYF 4MEYE 3I4MF 4MEXE 3HOZF 4A3LF 5C44F 2VUMF 2R93F 5FLMF 4G7ZE 3H3VG 5E17E 5C4JF 3PO2F
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4A3E F;  4C3I F;  4YFN E;  3DXJ E;  3S2H F;  3PO3 F;  3M3Y F;  2JA8 F;  2NVX F;  2JA7 F;  5M3F F;  3RZO F;  1I3Q F;  2JA6 F;  5M5X F;  1SFO F;  3S1R F;  4YG2 E;  4XLP E;  4G7H E;  4A3F F;  1Y1W F;  4Q4Z E;  3GTL F;  2A6H E;  3M4O F;  5BYH E;  5D4C E;  3HOV F;  5IP9 F;  1YNJ K;  4BY7 F;  3S17 F;  4C3J F;  3CQZ F;  5IYD F;  4KN7 E;  4C3H F;  3S1M F;  4X6A F;  2E2I F;  2WAQ K;  4A3G F;  1I6H F;  4LK0 E;  4OIQ E;  1YNN K;  4Y7N F;  3HOW F;  3GTJ F;  4LK1 E;  1Y1V F;  5E18 E;  3HOX F;  2A68 E;  4KN4 E;  3RZD F;  5TMF E;  2PPB E;  5IPL E;  1HQM E;  4G7O E;  2A6E E;  2YU9 F;  2O5J E;  4XSZ E;  5M5W F;  4A3D F;  1IW7 E;  5IYC F;  5D4E E;  1I50 F;  4A93 F;  1TWC F;  4GZY E;  4XSX E;  2NVT F;  3S1N F;  5M3M F;  3GTM F;  3H0G F;  3I4N F;  3FKI F;  4A3M F;  3GTK F;  5FJ8 F;  3HOY F;  4AYB K;  2R7Z F;  5M5Y F;  2PMZ K;  4YFK E;  4A3J F;  3GTP F;  4BY1 F;  4A3B F;  1SMY E;  4C2M F;  2E2H F;  4A3I F;  2B63 F;  3HOU F;  1I6V E;  2CW0 E;  1TWF F;  5C4X F;  4KMU E;  2WB1 I;  4BXX F;  1K83 F;  2E2J F;  1ZYR E;  4Q5S E;  4XLN E;  3HKZ K;  2Y0S I;  2NVQ F;  3GTO F;  4LJZ E;  1TWH F;  4BBS F;  4LLG E;  4OIR E;  3GTG F;  1R9T F;  3K7A F;  3S1Q F;  1TWG F;  1TWA F;  5C3E F;  1QKL A;  3WOD E;  4ZH4 E;  4OIO E;  3GTQ F;  3S15 F;  5TMC E;  1WCM F;  4JK1 E;  3S2D F;  5IYB F;  2A69 E;  3S14 F;  4OIP E;  3S16 F;  4OIN E;  5IP7 F;  2BE5 E;  4BBR F;  2JA5 F;  5D4D E;  4A3K F;  3EQL E;  4Y52 F;  4MQ9 E;  2R92 F;  2O5I E;  4YFX E;  4A3C F;  2NVY F;  4MEY E;  3I4M F;  4MEX E;  3HOZ F;  4A3L F;  5C44 F;  2VUM F;  2R93 F;  5FLM F;  4G7Z E;  3H3V G;  5E17 E;  5C4J F;  3PO2 F; 
#chains in the Genus database with same CATH topology
 2NVQ E;  2Y0S H;  4C3I F;  4YFN E;  3DXJ E;  4A3E F;  3GTO E;  3S2H F;  3PO3 F;  3M3Y F;  2JA8 F;  1DZF A;  2NVX F;  2JA7 F;  5M3F F;  1R9T E;  3K7A E;  1I3Q F;  2JA6 F;  3RZO F;  4A3C E;  3S1Q E;  5M5X F;  1TWA E;  5C3E E;  3HOZ E;  4A3L E;  1SFO F;  2VUM E;  3S1R F;  4YG2 E;  5FLM E;  4XLP E;  4G7H E;  4A3F F;  4Q4Z E;  1Y1W F;  2A6H E;  3GTL F;  5BYH E;  5D4C E;  3GTQ E;  3M4O F;  3S15 E;  3HOV F;  1WCM E;  1YNJ K;  5IP9 F;  4BY7 F;  3PO3 E;  3S2D E;  2JA8 E;  3S17 F;  3S2H E;  4C3J F;  3CQZ F;  5IYD F;  4KN7 E;  3S14 E;  4C3H F;  2JA6 E;  4QIW H;  3S1M F;  4X6A F;  2E2I F;  2WAQ K;  5IP7 E;  4BBR E;  1I6H F;  4LK0 E;  4A3G F;  4OIQ E;  3HOV E;  1EIK A;  4A3K E;  1YNN K;  4Y7N F;  5IP9 E;  3GTJ F;  4LK1 E;  1Y1V F;  3HOW F;  4BY7 E;  5E18 E;  3HOX F;  2A68 E;  4KN4 E;  4C3H E;  3RZD F;  4Y52 E;  5TMF E;  4AYB H;  2R92 E;  2PPB E;  4X6A E;  5IPL E;  2PMZ H;  1HQM E;  4G7O E;  2A6E E;  2NVY E;  2YU9 F;  1I6H E;  2O5J E;  4XSZ E;  5M5W F;  3I4M E;  4A3D F;  4Y7N E;  3GTJ E;  1IW7 E;  5C44 E;  5IYC F;  5D4E E;  2R93 E;  1I50 F;  3HOX E;  4QIW K;  5C4J E;  3RZD E;  3PO2 E;  4A3E E;  1TWC F;  4C3I E;  4XSX E;  2NVT F;  4A93 F;  4GZY E;  3M3Y E;  2NVX E;  2JA7 E;  5M3M F;  3GTM F;  3S1N F;  3H0G F;  5M3F E;  3I4N F;  1I3Q E;  3RZO E;  3FKI F;  5M5W E;  5M5X E;  4A3M F;  3HKZ H;  1SFO E;  3GTK F;  5FJ8 F;  3S1R E;  1Y1W E;  3HOY F;  4AYB K;  4A3F E;  3GTL E;  3M4O E;  2R7Z F;  5M5Y F;  2PMZ K;  4YFK E;  4A3J F;  3GTP F;  4BY1 F;  3S17 E;  5IYD E;  3CQZ E;  4C3J E;  1SMY E;  4C2M F;  2E2H F;  4A3B F;  4A3I F;  2B63 F;  3HOU F;  3FKI E;  1I6V E;  2CW0 E;  1TWF F;  3S1M E;  5C4X F;  2E2I E;  4KMU E;  2WB1 I;  5FJ8 E;  4BXX F;  1K83 F;  2E2J F;  4A3G E;  1ZYR E;  4Q5S E;  2KRX A;  3HOW E;  1Y1V E;  4A3B E;  4XLN E;  4C2M E;  3HKZ K;  2Y0S I;  2NVQ F;  3GTO F;  4LJZ E;  1TWH F;  4BBS F;  4LLG E;  4OIR E;  3GTG F;  1R9T F;  4BXX E;  3K7A F;  2E2J E;  2YU9 E;  3S1Q F;  1TWG F;  4A3D E;  1TWA F;  5C3E F;  1QKL A;  3WOD E;  5IYC E;  4ZH4 E;  1I50 E;  4OIO E;  3GTQ F;  3S15 F;  5TMC E;  2WAQ H;  3H3V F;  4A93 E;  1TWC E;  1WCM F;  1TWH E;  4JK1 E;  2NVT E;  3S2D F;  4BBS E;  5IYB F;  3S1N E;  2A69 E;  5M3M E;  3GTG E;  3GTM E;  3H0G E;  4OIP E;  3I4N E;  3S14 F;  3S16 F;  4OIN E;  1TWG E;  4A3M E;  3GTK E;  3HOY E;  5IP7 F;  2BE5 E;  2R7Z E;  4BBR F;  2JA5 F;  5M5Y E;  5D4D E;  4A3K F;  4A3J E;  3EQL E;  3GTP E;  4BY1 E;  5IYB E;  2E2H E;  4Y52 F;  4A3I E;  2B63 E;  3HOU E;  4MQ9 E;  2R92 F;  3S16 E;  2O5I E;  5C4X E;  1TWF E;  2WB1 H;  4YFX E;  4A3C F;  1K83 E;  2NVY F;  4MEY E;  2JA5 E;  3I4M F;  4MEX E;  3HOZ F;  4A3L F;  5C44 F;  2VUM F;  2R93 F;  5FLM F;  4G7Z E;  3H3V G;  5E17 E;  5C4J F;  3PO2 F; 
#chains in the Genus database with same CATH homology
 4A3E F;  4C3I F;  4YFN E;  3DXJ E;  3S2H F;  3PO3 F;  3M3Y F;  2JA8 F;  2NVX F;  2JA7 F;  5M3F F;  3RZO F;  1I3Q F;  2JA6 F;  5M5X F;  1SFO F;  3S1R F;  4YG2 E;  4XLP E;  4G7H E;  4A3F F;  1Y1W F;  4Q4Z E;  3GTL F;  2A6H E;  3M4O F;  5BYH E;  5D4C E;  3HOV F;  5IP9 F;  1YNJ K;  4BY7 F;  3S17 F;  4C3J F;  3CQZ F;  5IYD F;  4KN7 E;  4C3H F;  3S1M F;  4X6A F;  2E2I F;  2WAQ K;  4A3G F;  1I6H F;  4LK0 E;  4OIQ E;  1YNN K;  4Y7N F;  3HOW F;  3GTJ F;  4LK1 E;  1Y1V F;  5E18 E;  3HOX F;  2A68 E;  4KN4 E;  3RZD F;  5TMF E;  2PPB E;  5IPL E;  1HQM E;  4G7O E;  2A6E E;  2YU9 F;  2O5J E;  4XSZ E;  5M5W F;  4A3D F;  1IW7 E;  5IYC F;  5D4E E;  1I50 F;  4QIW K;  4A93 F;  1TWC F;  4GZY E;  4XSX E;  2NVT F;  3S1N F;  5M3M F;  3GTM F;  3H0G F;  3I4N F;  3FKI F;  4A3M F;  3GTK F;  5FJ8 F;  3HOY F;  4AYB K;  2R7Z F;  5M5Y F;  2PMZ K;  4YFK E;  4A3J F;  3GTP F;  4BY1 F;  4A3B F;  1SMY E;  4C2M F;  2E2H F;  4A3I F;  2B63 F;  3HOU F;  1I6V E;  2CW0 E;  1TWF F;  5C4X F;  4KMU E;  2WB1 I;  4BXX F;  1K83 F;  2E2J F;  1ZYR E;  4Q5S E;  2KRX A;  4XLN E;  3HKZ K;  2Y0S I;  2NVQ F;  3GTO F;  4LJZ E;  1TWH F;  4BBS F;  4LLG E;  4OIR E;  3GTG F;  1R9T F;  3K7A F;  3S1Q F;  1TWG F;  1TWA F;  5C3E F;  1QKL A;  3WOD E;  4ZH4 E;  4OIO E;  3GTQ F;  3S15 F;  5TMC E;  1WCM F;  4JK1 E;  3S2D F;  5IYB F;  2A69 E;  3S14 F;  4OIP E;  3S16 F;  4OIN E;  5IP7 F;  2BE5 E;  4BBR F;  2JA5 F;  5D4D E;  4A3K F;  3EQL E;  4Y52 F;  4MQ9 E;  2R92 F;  2O5I E;  4YFX E;  4A3C F;  2NVY F;  4MEY E;  3I4M F;  4MEX E;  3HOZ F;  4A3L F;  5C44 F;  2VUM F;  2R93 F;  5FLM F;  4G7Z E;  3H3V G;  5E17 E;  5C4J F;  3PO2 F; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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