5CYNA

Jc virus large t-antigen origin binding domain f258l mutant
Total Genus 32
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
32
sequence length
127
structure length
127
Chain Sequence
VEDPKDFPVDLHAFLSQAVFSNRTVASFAVYTTKEKAQILYKKLMEKYSVTFISRHGFGGHNILFFLTPHRHRVSAINNYCQKLCTFSFLICKGVNKEYLFYSALCRQPYAVVEESIQGGLKEHDLN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural Based Analyses of the JC Virus T-Antigen F258L Mutant Provides Evidence for DNA Dependent Conformational Changes in the C-Termini of Polyomavirus Origin Binding Domains.
pubmed doi rcsb
molecule tags Viral protein, dna binding protein
source organism Jc polyomavirus
molecule keywords Large T antigen
total genus 32
structure length 127
sequence length 127
ec nomenclature ec 3.6.4.-:
pdb deposition date 2015-07-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02217 T_Ag_DNA_bind Origin of replication binding protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1310.20 Alpha Beta 3-Layer(aba) Sandwich Replication Protein E1; Chain: A, Replication Protein E1; Chain: A, 5cynA00
1Z1DB 4LIFA 2HW0A 2NL8A 2IPRA 5CYNA 1RZ9A 2TBDA 3QN2A 5DCXA 5BYGA 2FUFA 4ZO0A 1UUTA 1M55A 4ZQ9A 4GDFA 3QFQA 5D9IA 4NBPA 4FGNA 4FB3A 1L5IA 4LMDA 2ITJA 1L2MA 2ITLA 1TBDA 3QK2A 2NTCA 2IF9A
chains in the Genus database with same CATH superfamily
1Z1DB 4LIFA 2HW0A 2NL8A 2IPRA 5CYNA 4U87A 1KSXA 4KW3A 1RZ9A 2TBDA 3QN2A 5DCXA 5BYGA 1KSYA 2FUFA 4ZO0A 3DKYA 1UUTA 1M55A 1F08A 4ZQ9A 4GDFA 3QFQA 5D9IA 1R9WA 4NBPA 4FGNA 4FB3A 1L5IA 4LMDA 2ITJA 1L2MA 2ITLA 1TBDA 3QK2A 2NTCA 2IF9A 3DKXA
chains in the Genus database with same CATH topology
1Z1DB 4LIFA 2HW0A 2NL8A 2IPRA 5CYNA 4U87A 1KSXA 4KW3A 1RZ9A 2TBDA 3QN2A 5DCXA 5BYGA 1KSYA 2FUFA 4ZO0A 3DKYA 1UUTA 1M55A 1F08A 4ZQ9A 4GDFA 3QFQA 5D9IA 1R9WA 4NBPA 4FGNA 4FB3A 1L5IA 4LMDA 2ITJA 1L2MA 2ITLA 1TBDA 3QK2A 2NTCA 2IF9A 3DKXA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1Z1D B;  4LIF A;  2HW0 A;  2NL8 A;  2IPR A;  5CYN A;  1RZ9 A;  2TBD A;  3QN2 A;  5DCX A;  5BYG A;  2FUF A;  4ZO0 A;  1UUT A;  1M55 A;  4ZQ9 A;  4GDF A;  3QFQ A;  5D9I A;  4NBP A;  4FGN A;  4FB3 A;  1L5I A;  4LMD A;  2ITJ A;  1L2M A;  2ITL A;  1TBD A;  3QK2 A;  2NTC A;  2IF9 A; 
#chains in the Genus database with same CATH topology
 1Z1D B;  4LIF A;  2HW0 A;  2NL8 A;  2IPR A;  5CYN A;  4U87 A;  1KSX A;  4KW3 A;  1RZ9 A;  2TBD A;  3QN2 A;  5DCX A;  5BYG A;  1KSY A;  2FUF A;  4ZO0 A;  3DKY A;  1UUT A;  1M55 A;  1F08 A;  4ZQ9 A;  4GDF A;  3QFQ A;  5D9I A;  1R9W A;  4NBP A;  4FGN A;  4FB3 A;  1L5I A;  4LMD A;  2ITJ A;  1L2M A;  2ITL A;  1TBD A;  3QK2 A;  2NTC A;  2IF9 A;  3DKX A; 
#chains in the Genus database with same CATH homology
 1Z1D B;  4LIF A;  2HW0 A;  2NL8 A;  2IPR A;  5CYN A;  4U87 A;  1KSX A;  4KW3 A;  1RZ9 A;  2TBD A;  3QN2 A;  5DCX A;  5BYG A;  1KSY A;  2FUF A;  4ZO0 A;  3DKY A;  1UUT A;  1M55 A;  1F08 A;  4ZQ9 A;  4GDF A;  3QFQ A;  5D9I A;  1R9W A;  4NBP A;  4FGN A;  4FB3 A;  1L5I A;  4LMD A;  2ITJ A;  1L2M A;  2ITL A;  1TBD A;  3QK2 A;  2NTC A;  2IF9 A;  3DKX A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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