5CYNA

Jc virus large t-antigen origin binding domain f258l mutant
Total Genus 32
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
32
sequence length
127
structure length
127
Chain Sequence
VEDPKDFPVDLHAFLSQAVFSNRTVASFAVYTTKEKAQILYKKLMEKYSVTFISRHGFGGHNILFFLTPHRHRVSAINNYCQKLCTFSFLICKGVNKEYLFYSALCRQPYAVVEESIQGGLKEHDLN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural Based Analyses of the JC Virus T-Antigen F258L Mutant Provides Evidence for DNA Dependent Conformational Changes in the C-Termini of Polyomavirus Origin Binding Domains.
pubmed doi rcsb
molecule keywords Large T antigen
molecule tags Viral protein, dna binding protein
source organism Jc polyomavirus
total genus 32
structure length 127
sequence length 127
ec nomenclature ec 3.6.4.-:
pdb deposition date 2015-07-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02217 T_Ag_DNA_bind Origin of replication binding protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1310.20 Alpha Beta 3-Layer(aba) Sandwich Replication Protein E1; Chain: A, Replication Protein E1; Chain: A, 5cynA00
2IF9A 1L2MA 4LMDA 1M55A 3QK2A 4FGNA 4ZO0A 4LIFA 4NBPA 2TBDA 1L5IA 2ITLA 3QN2A 4GDFA 5BYGA 5DCXA 2ITJA 5CYNA 4FB3A 2HW0A 1RZ9A 2NL8A 2IPRA 3QFQA 2NTCA 4ZQ9A 5D9IA 1UUTA 2FUFA 1TBDA 1Z1DB
chains in the Genus database with same CATH superfamily
2IF9A 1L2MA 1KSXA 4LMDA 4U87A 1M55A 1R9WA 3QK2A 1F08A 4FGNA 4ZO0A 4LIFA 4NBPA 2TBDA 3DKYA 1L5IA 2ITLA 3QN2A 4GDFA 3DKXA 5BYGA 4KW3A 5DCXA 2ITJA 5CYNA 4FB3A 2HW0A 1RZ9A 2NL8A 2IPRA 3QFQA 2NTCA 4ZQ9A 5D9IA 1KSYA 1UUTA 2FUFA 1TBDA 1Z1DB
chains in the Genus database with same CATH topology
2IF9A 1L2MA 1KSXA 4LMDA 4U87A 1M55A 1R9WA 3QK2A 1F08A 4FGNA 4ZO0A 4LIFA 4NBPA 2TBDA 3DKYA 1L5IA 2ITLA 3QN2A 4GDFA 3DKXA 5BYGA 4KW3A 5DCXA 2ITJA 5CYNA 4FB3A 2HW0A 1RZ9A 2NL8A 2IPRA 3QFQA 2NTCA 4ZQ9A 5D9IA 1KSYA 1UUTA 2FUFA 1TBDA 1Z1DB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2IF9 A;  1L2M A;  4LMD A;  1M55 A;  3QK2 A;  4FGN A;  4ZO0 A;  4LIF A;  4NBP A;  2TBD A;  1L5I A;  2ITL A;  3QN2 A;  4GDF A;  5BYG A;  5DCX A;  2ITJ A;  5CYN A;  4FB3 A;  2HW0 A;  1RZ9 A;  2NL8 A;  2IPR A;  3QFQ A;  2NTC A;  4ZQ9 A;  5D9I A;  1UUT A;  2FUF A;  1TBD A;  1Z1D B; 
#chains in the Genus database with same CATH topology
 2IF9 A;  1L2M A;  1KSX A;  4LMD A;  4U87 A;  1M55 A;  1R9W A;  3QK2 A;  1F08 A;  4FGN A;  4ZO0 A;  4LIF A;  4NBP A;  2TBD A;  3DKY A;  1L5I A;  2ITL A;  3QN2 A;  4GDF A;  3DKX A;  5BYG A;  4KW3 A;  5DCX A;  2ITJ A;  5CYN A;  4FB3 A;  2HW0 A;  1RZ9 A;  2NL8 A;  2IPR A;  3QFQ A;  2NTC A;  4ZQ9 A;  5D9I A;  1KSY A;  1UUT A;  2FUF A;  1TBD A;  1Z1D B; 
#chains in the Genus database with same CATH homology
 2IF9 A;  1L2M A;  1KSX A;  4LMD A;  4U87 A;  1M55 A;  1R9W A;  3QK2 A;  1F08 A;  4FGN A;  4ZO0 A;  4LIF A;  4NBP A;  2TBD A;  3DKY A;  1L5I A;  2ITL A;  3QN2 A;  4GDF A;  3DKX A;  5BYG A;  4KW3 A;  5DCX A;  2ITJ A;  5CYN A;  4FB3 A;  2HW0 A;  1RZ9 A;  2NL8 A;  2IPR A;  3QFQ A;  2NTC A;  4ZQ9 A;  5D9I A;  1KSY A;  1UUT A;  2FUF A;  1TBD A;  1Z1D B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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