5CYNA

Jc virus large t-antigen origin binding domain f258l mutant
Total Genus 32
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
32
sequence length
127
structure length
127
Chain Sequence
VEDPKDFPVDLHAFLSQAVFSNRTVASFAVYTTKEKAQILYKKLMEKYSVTFISRHGFGGHNILFFLTPHRHRVSAINNYCQKLCTFSFLICKGVNKEYLFYSALCRQPYAVVEESIQGGLKEHDLN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural Based Analyses of the JC Virus T-Antigen F258L Mutant Provides Evidence for DNA Dependent Conformational Changes in the C-Termini of Polyomavirus Origin Binding Domains.
pubmed doi rcsb
molecule keywords Large T antigen
molecule tags Viral protein, dna binding protein
source organism Jc polyomavirus
total genus 32
structure length 127
sequence length 127
ec nomenclature ec 3.6.4.-:
pdb deposition date 2015-07-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02217 T_Ag_DNA_bind Origin of replication binding protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1310.20 Alpha Beta 3-Layer(aba) Sandwich Replication Protein E1; Chain: A, Replication Protein E1; Chain: A, 5cynA00
4NBPA 1L2MA 5CYNA 2ITJA 2IF9A 2NTCA 1RZ9A 2ITLA 1L5IA 5BYGA 1UUTA 4GDFA 2FUFA 3QK2A 1Z1DB 1M55A 4LIFA 2HW0A 3QFQA 2TBDA 2NL8A 4ZO0A 4FGNA 5D9IA 4LMDA 3QN2A 4FB3A 2IPRA 5DCXA 1TBDA 4ZQ9A
chains in the Genus database with same CATH superfamily
4NBPA 1L2MA 5CYNA 2ITJA 2IF9A 1KSXA 1KSYA 2NTCA 1RZ9A 2ITLA 1L5IA 5BYGA 1UUTA 4GDFA 2FUFA 3QK2A 1Z1DB 3DKYA 1M55A 4LIFA 2HW0A 1F08A 3QFQA 2TBDA 2NL8A 1R9WA 4U87A 4ZO0A 4FGNA 5D9IA 4LMDA 3QN2A 4FB3A 2IPRA 5DCXA 4KW3A 1TBDA 3DKXA 4ZQ9A
chains in the Genus database with same CATH topology
4NBPA 1L2MA 5CYNA 2ITJA 2IF9A 1KSXA 1KSYA 2NTCA 1RZ9A 2ITLA 1L5IA 5BYGA 1UUTA 4GDFA 2FUFA 3QK2A 1Z1DB 3DKYA 1M55A 4LIFA 2HW0A 1F08A 3QFQA 2TBDA 2NL8A 1R9WA 4U87A 4ZO0A 4FGNA 5D9IA 4LMDA 3QN2A 4FB3A 2IPRA 5DCXA 4KW3A 1TBDA 3DKXA 4ZQ9A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4NBP A;  1L2M A;  5CYN A;  2ITJ A;  2IF9 A;  2NTC A;  1RZ9 A;  2ITL A;  1L5I A;  5BYG A;  1UUT A;  4GDF A;  2FUF A;  3QK2 A;  1Z1D B;  1M55 A;  4LIF A;  2HW0 A;  3QFQ A;  2TBD A;  2NL8 A;  4ZO0 A;  4FGN A;  5D9I A;  4LMD A;  3QN2 A;  4FB3 A;  2IPR A;  5DCX A;  1TBD A;  4ZQ9 A; 
#chains in the Genus database with same CATH topology
 4NBP A;  1L2M A;  5CYN A;  2ITJ A;  2IF9 A;  1KSX A;  1KSY A;  2NTC A;  1RZ9 A;  2ITL A;  1L5I A;  5BYG A;  1UUT A;  4GDF A;  2FUF A;  3QK2 A;  1Z1D B;  3DKY A;  1M55 A;  4LIF A;  2HW0 A;  1F08 A;  3QFQ A;  2TBD A;  2NL8 A;  1R9W A;  4U87 A;  4ZO0 A;  4FGN A;  5D9I A;  4LMD A;  3QN2 A;  4FB3 A;  2IPR A;  5DCX A;  4KW3 A;  1TBD A;  3DKX A;  4ZQ9 A; 
#chains in the Genus database with same CATH homology
 4NBP A;  1L2M A;  5CYN A;  2ITJ A;  2IF9 A;  1KSX A;  1KSY A;  2NTC A;  1RZ9 A;  2ITL A;  1L5I A;  5BYG A;  1UUT A;  4GDF A;  2FUF A;  3QK2 A;  1Z1D B;  3DKY A;  1M55 A;  4LIF A;  2HW0 A;  1F08 A;  3QFQ A;  2TBD A;  2NL8 A;  1R9W A;  4U87 A;  4ZO0 A;  4FGN A;  5D9I A;  4LMD A;  3QN2 A;  4FB3 A;  2IPR A;  5DCX A;  4KW3 A;  1TBD A;  3DKX A;  4ZQ9 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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