5D4DE

Crystal structure of thermus thermophilus product complex for transcription initiation with nad and ctp
Total Genus 24
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
24
sequence length
94
structure length
94
Chain Sequence
AEPGIDKLFGMVDSKYRLTVVVAKRAQQLLRHGFKNTVLEPEERPKMQTLEGLFDDPNAVTWAMKELLTGRLVFGENLVPEDRLQKEMERLYPV
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The mechanism of RNA 5' capping with NAD(+), NADH and desphospho-CoA.
pubmed doi rcsb
molecule tags Transcription/dna
source organism Thermus thermophilus (strain hb27 / atcc baa-163 / dsm 7039)
molecule keywords DNA-directed RNA polymerase subunit alpha
total genus 24
structure length 94
sequence length 94
chains with identical sequence O
ec nomenclature ec 2.7.7.6: DNA-directed RNA polymerase.
pdb deposition date 2015-08-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF01192 RNA_pol_Rpb6 RNA polymerase Rpb6
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.940.10 Alpha Beta Alpha-Beta Complex Eukaryotic RPB6 RNA polymerase subunit Eukaryotic RPB6 RNA polymerase subunit 5d4dE00
4G7OE 2E2HF 5E18E 4LK0E 4Q5SE 4MQ9E 3S1QF 3GTGF 5IYCF 1HQME 1SFOF 3S2DF 4A3DF 4A3IF 5BYHE 4G7ZE 5C4XF 4A3EF 5TMFE 1SMYE 4BY1F 4OIPE 5M5YF 2O5JE 2A6HE 4YFXE 3WODE 3S17F 3HOVF 3S2HF 3PO2F 4A3JF 3HOZF 3DXJE 2WB1I 1ZYRE 4C3HF 1WCMF 3PO3F 2PPBE 3S15F 5IPLE 4BBRF 4GZYE 2JA5F 3I4MF 1Y1VF 3HKZK 2JA6F 4OIQE 1TWCF 4A3GF 1I6VE 1R9TF 2VUMF 2PMZK 4C2MF 1K83F 5D4EE 3HOUF 1I50F 5C3EF 5D4DE 2JA7F 3M4OF 4A93F 5C4JF 3H0GF 3M3YF 4Y52F 4YFKE 4A3BF 1TWHF 3H3VG 4A3CF 5IP7F 4XSXE 4OIRE 3K7AF 4JK1E 4BBSF 5IYBF 3GTKF 2R7ZF 1Y1WF 3GTLF 3HOWF 2BE5E 3I4NF 3S16F 4XSZE 5M3FF 3RZDF 3GTOF 5M3MF 4LLGE 2R92F 4BXXF 4MEXE 1YNNK 3FKIF 2A68E 3RZOF 2R93F 5E17E 4KN4E 4A3KF 4A3FF 2A6EE 4XLNE 5TMCE 2NVTF 1TWAF 4OINE 4AYBK 2A69E 3GTPF 2CW0E 3GTQF 1IW7E 4KMUE 3HOYF 2NVYF 2WAQK 5C44F 2O5IE 3S1NF 1TWFF 4A3LF 4KN7E 4ZH4E 1YNJK 4A3MF 4Q4ZE 2Y0SI 4BY7F 5IYDF 2YU9F 4C3JF 4OIOE 2NVQF 4LJZE 2E2JF 5M5XF 3CQZF 1I3QF 4LK1E 5FLMF 4MEYE 1QKLA 3S1MF 3HOXF 3GTJF 3S1RF 2NVXF 3S14F 3EQLE 5FJ8F 2JA8F 5IP9F 4X6AF 3GTMF 1I6HF 1TWGF 4C3IF 4YFNE 5D4CE 2B63F 2E2IF 4G7HE 5M5WF 4Y7NF 4YG2E 4XLPE
chains in the Genus database with same CATH superfamily
4G7OE 2E2HF 4A3KE 5E18E 4LK0E 2WAQH 4Q5SE 4MQ9E 3S1QF 5C3EE 3GTGF 5IYCF 1HQME 1SFOF 3S2DF 2NVTE 1TWAE 4A3IF 4A93E 4A3DF 5BYHE 4Y52E 4G7ZE 5C4XF 4A3EF 4A3CE 5TMFE 1SMYE 2NVYE 4QIWH 5C44E 3K7AE 3S1NE 1TWFE 4OIPE 4BY1F 5M5YF 3RZOE 4BBSE 2O5JE 3H3VF 4A3ME 2A6HE 4YFXE 3WODE 3S17F 3HOVF 3S2HF 3PO2F 4A3JF 4BY7E 5IYDE 3HOZF 3DXJE 2WB1I 2YU9E 1ZYRE 4C3HF 3I4NE 3S16E 3GTOE 1WCMF 2NVQE 5M5XE 3PO3F 3CQZE 2PPBE 2R92E 3FKIE 3S15F 5IPLE 4BBRF 4GZYE 2JA5F 3I4MF 1DZFA 1Y1VF 3HKZK 3GTJE 2JA6F 4AYBH 3S1RE 2NVXE 3S14E 4A3FE 4OIQE 1TWCF 4A3GF 5FJ8E 1I6VE 1R9TF 2VUMF 2PMZK 4X6AE 3GTME 4C2MF 1I6HE 1TWGE 1K83F 5D4EE 3GTPE 3HOUF 3GTQE 1I50F 5C3EF 5D4DE 2JA7F 3M4OF 3HOYE 4A93F 2B63E 5C4JF 3H0GF 4A3LE 3M3YF 4Y52F 4YFKE 5M5WE 4A3BF 1TWHF 4Y7NE 3H3VG 5IP7F 4XSXE 4OIRE 4A3CF 3K7AF 4JK1E 2E2HE 5IYBF 4BBSF 3GTKF 4C3JE 2R7ZF 1Y1WF 2E2JE 3GTLF 3HOWF 3S1QE 2Y0SH 1I3QE 5FLME 2BE5E 5IYCE 1SFOE 4XSZE 5M3FF 3RZDF 4A3IE 3GTOF 4QIWK 5M3MF 3HOXE 3S16F 4LLGE 3S1ME 2R92F 4BXXF 4MEXE 1YNNK 3FKIF 2A68E 5C4XE 3RZOF 5M5YE 2R93F 5E17E 2JA8E 4KN4E 5IP9E 4A3KF 4A3FF 3S2HE 3PO2E 2A6EE 4A3JE 4XLNE 4C3IE 5TMCE 4C3HE 1WCME 3PO3E 2E2IE 1TWAF 2NVTF 4OINE 3S15E 2PMZH 4AYBK 2A69E 4BBRE 2CW0E 2JA5E 1IW7E 4KMUE 3GTPF 3GTQF 3HOYF 2NVYF 1Y1VE 2WAQK 5C44F 2O5IE 1TWFF 3S1NF 4A3LF 4KN7E 4ZH4E 1YNJK 4A3MF 1TWCE 4Q4ZE 4A3GE 2Y0SI 4BY7F 1R9TE 2VUME 5IYDF 2YU9F 4C3JF 3GTGE 3S2DE 4C2ME 4OIOE 1K83E 4LJZE 2E2JF 2NVQF 5M5XF 3CQZF 3HOUE 1I50E 1I3QF 4LK1E 5FLMF 4MEYE 4A3EE 1QKLA 2JA7E 3M4OE 5C4JE 3H0GE 3S1MF 4BY1E 3HOXF 3M3YE 3GTJF 4A3BE 1TWHE 3S1RF 5IP7E 2NVXF 3EQLE 3HOVE 3S14F 3S17E 3HKZH 1EIKA 5IYBE 2KRXA 5FJ8F 2JA8F 3GTKE 3HOZE 2R7ZE 5IP9F 4A3DE 4X6AF 1Y1WE 3GTMF 3I4NF 1I6HF 1TWGF 3GTLE 3HOWE 4C3IF 4YFNE 5D4CE 3RZDE 5M3FE 2WB1H 3I4ME 5M3ME 2B63F 2E2IF 2JA6E 4G7HE 4BXXE 5M5WF 4Y7NF 4YG2E 2R93E 4XLPE
chains in the Genus database with same CATH topology
4G7OE 2E2HF 5E18E 4LK0E 4Q5SE 4MQ9E 3S1QF 3GTGF 5IYCF 1HQME 1SFOF 3S2DF 4A3DF 4A3IF 5BYHE 4G7ZE 5C4XF 4A3EF 5TMFE 1SMYE 4BY1F 4OIPE 5M5YF 2O5JE 2A6HE 4YFXE 3WODE 3S17F 3HOVF 3S2HF 3PO2F 4A3JF 3HOZF 3DXJE 2WB1I 1ZYRE 4C3HF 1WCMF 3PO3F 2PPBE 3S15F 5IPLE 4BBRF 4GZYE 2JA5F 3I4MF 1Y1VF 3HKZK 2JA6F 4OIQE 1TWCF 4A3GF 1I6VE 1R9TF 2VUMF 2PMZK 4C2MF 1K83F 5D4EE 3HOUF 1I50F 5C3EF 5D4DE 2JA7F 3M4OF 4A93F 5C4JF 3H0GF 3M3YF 4Y52F 4YFKE 4A3BF 1TWHF 3H3VG 4A3CF 5IP7F 4XSXE 4OIRE 3K7AF 4JK1E 4BBSF 5IYBF 3GTKF 2R7ZF 1Y1WF 3GTLF 3HOWF 2BE5E 3I4NF 3S16F 4XSZE 5M3FF 3RZDF 3GTOF 4QIWK 5M3MF 4LLGE 2R92F 4BXXF 4MEXE 1YNNK 3FKIF 2A68E 3RZOF 2R93F 5E17E 4KN4E 4A3KF 4A3FF 2A6EE 4XLNE 5TMCE 2NVTF 1TWAF 4OINE 4AYBK 2A69E 3GTPF 2CW0E 3GTQF 1IW7E 4KMUE 3HOYF 2NVYF 2WAQK 5C44F 2O5IE 3S1NF 1TWFF 4A3LF 4KN7E 4ZH4E 1YNJK 4A3MF 4Q4ZE 2Y0SI 4BY7F 5IYDF 2YU9F 4C3JF 4OIOE 2NVQF 4LJZE 2E2JF 5M5XF 3CQZF 1I3QF 4LK1E 5FLMF 4MEYE 1QKLA 3S1MF 3HOXF 3GTJF 3S1RF 2NVXF 3S14F 3EQLE 2KRXA 5FJ8F 2JA8F 5IP9F 4X6AF 3GTMF 1I6HF 1TWGF 4C3IF 4YFNE 5D4CE 2B63F 2E2IF 4G7HE 5M5WF 4Y7NF 4YG2E 4XLPE
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4G7O E;  2E2H F;  5E18 E;  4LK0 E;  4Q5S E;  4MQ9 E;  3S1Q F;  3GTG F;  5IYC F;  1HQM E;  1SFO F;  3S2D F;  4A3D F;  4A3I F;  5BYH E;  4G7Z E;  5C4X F;  4A3E F;  5TMF E;  1SMY E;  4BY1 F;  4OIP E;  5M5Y F;  2O5J E;  2A6H E;  4YFX E;  3WOD E;  3S17 F;  3HOV F;  3S2H F;  3PO2 F;  4A3J F;  3HOZ F;  3DXJ E;  2WB1 I;  1ZYR E;  4C3H F;  1WCM F;  3PO3 F;  2PPB E;  3S15 F;  5IPL E;  4BBR F;  4GZY E;  2JA5 F;  3I4M F;  1Y1V F;  3HKZ K;  2JA6 F;  4OIQ E;  1TWC F;  4A3G F;  1I6V E;  1R9T F;  2VUM F;  2PMZ K;  4C2M F;  1K83 F;  5D4E E;  3HOU F;  1I50 F;  5C3E F;  5D4D E;  2JA7 F;  3M4O F;  4A93 F;  5C4J F;  3H0G F;  3M3Y F;  4Y52 F;  4YFK E;  4A3B F;  1TWH F;  3H3V G;  4A3C F;  5IP7 F;  4XSX E;  4OIR E;  3K7A F;  4JK1 E;  4BBS F;  5IYB F;  3GTK F;  2R7Z F;  1Y1W F;  3GTL F;  3HOW F;  2BE5 E;  3I4N F;  3S16 F;  4XSZ E;  5M3F F;  3RZD F;  3GTO F;  5M3M F;  4LLG E;  2R92 F;  4BXX F;  4MEX E;  1YNN K;  3FKI F;  2A68 E;  3RZO F;  2R93 F;  5E17 E;  4KN4 E;  4A3K F;  4A3F F;  2A6E E;  4XLN E;  5TMC E;  2NVT F;  1TWA F;  4OIN E;  4AYB K;  2A69 E;  3GTP F;  2CW0 E;  3GTQ F;  1IW7 E;  4KMU E;  3HOY F;  2NVY F;  2WAQ K;  5C44 F;  2O5I E;  3S1N F;  1TWF F;  4A3L F;  4KN7 E;  4ZH4 E;  1YNJ K;  4A3M F;  4Q4Z E;  2Y0S I;  4BY7 F;  5IYD F;  2YU9 F;  4C3J F;  4OIO E;  2NVQ F;  4LJZ E;  2E2J F;  5M5X F;  3CQZ F;  1I3Q F;  4LK1 E;  5FLM F;  4MEY E;  1QKL A;  3S1M F;  3HOX F;  3GTJ F;  3S1R F;  2NVX F;  3S14 F;  3EQL E;  5FJ8 F;  2JA8 F;  5IP9 F;  4X6A F;  3GTM F;  1I6H F;  1TWG F;  4C3I F;  4YFN E;  5D4C E;  2B63 F;  2E2I F;  4G7H E;  5M5W F;  4Y7N F;  4YG2 E;  4XLP E; 
#chains in the Genus database with same CATH topology
 4G7O E;  2E2H F;  4A3K E;  5E18 E;  4LK0 E;  2WAQ H;  4Q5S E;  4MQ9 E;  3S1Q F;  5C3E E;  3GTG F;  5IYC F;  1HQM E;  1SFO F;  3S2D F;  2NVT E;  1TWA E;  4A3I F;  4A93 E;  4A3D F;  5BYH E;  4Y52 E;  4G7Z E;  5C4X F;  4A3E F;  4A3C E;  5TMF E;  1SMY E;  2NVY E;  4QIW H;  5C44 E;  3K7A E;  3S1N E;  1TWF E;  4OIP E;  4BY1 F;  5M5Y F;  3RZO E;  4BBS E;  2O5J E;  3H3V F;  4A3M E;  2A6H E;  4YFX E;  3WOD E;  3S17 F;  3HOV F;  3S2H F;  3PO2 F;  4A3J F;  4BY7 E;  5IYD E;  3HOZ F;  3DXJ E;  2WB1 I;  2YU9 E;  1ZYR E;  4C3H F;  3I4N E;  3S16 E;  3GTO E;  1WCM F;  2NVQ E;  5M5X E;  3PO3 F;  3CQZ E;  2PPB E;  2R92 E;  3FKI E;  3S15 F;  5IPL E;  4BBR F;  4GZY E;  2JA5 F;  3I4M F;  1DZF A;  1Y1V F;  3HKZ K;  3GTJ E;  2JA6 F;  4AYB H;  3S1R E;  2NVX E;  3S14 E;  4A3F E;  4OIQ E;  1TWC F;  4A3G F;  5FJ8 E;  1I6V E;  1R9T F;  2VUM F;  2PMZ K;  4X6A E;  3GTM E;  4C2M F;  1I6H E;  1TWG E;  1K83 F;  5D4E E;  3GTP E;  3HOU F;  3GTQ E;  1I50 F;  5C3E F;  5D4D E;  2JA7 F;  3M4O F;  3HOY E;  4A93 F;  2B63 E;  5C4J F;  3H0G F;  4A3L E;  3M3Y F;  4Y52 F;  4YFK E;  5M5W E;  4A3B F;  1TWH F;  4Y7N E;  3H3V G;  5IP7 F;  4XSX E;  4OIR E;  4A3C F;  3K7A F;  4JK1 E;  2E2H E;  5IYB F;  4BBS F;  3GTK F;  4C3J E;  2R7Z F;  1Y1W F;  2E2J E;  3GTL F;  3HOW F;  3S1Q E;  2Y0S H;  1I3Q E;  5FLM E;  2BE5 E;  5IYC E;  1SFO E;  4XSZ E;  5M3F F;  3RZD F;  4A3I E;  3GTO F;  4QIW K;  5M3M F;  3HOX E;  3S16 F;  4LLG E;  3S1M E;  2R92 F;  4BXX F;  4MEX E;  1YNN K;  3FKI F;  2A68 E;  5C4X E;  3RZO F;  5M5Y E;  2R93 F;  5E17 E;  2JA8 E;  4KN4 E;  5IP9 E;  4A3K F;  4A3F F;  3S2H E;  3PO2 E;  2A6E E;  4A3J E;  4XLN E;  4C3I E;  5TMC E;  4C3H E;  1WCM E;  3PO3 E;  2E2I E;  1TWA F;  2NVT F;  4OIN E;  3S15 E;  2PMZ H;  4AYB K;  2A69 E;  4BBR E;  2CW0 E;  2JA5 E;  1IW7 E;  4KMU E;  3GTP F;  3GTQ F;  3HOY F;  2NVY F;  1Y1V E;  2WAQ K;  5C44 F;  2O5I E;  1TWF F;  3S1N F;  4A3L F;  4KN7 E;  4ZH4 E;  1YNJ K;  4A3M F;  1TWC E;  4Q4Z E;  4A3G E;  2Y0S I;  4BY7 F;  1R9T E;  2VUM E;  5IYD F;  2YU9 F;  4C3J F;  3GTG E;  3S2D E;  4C2M E;  4OIO E;  1K83 E;  4LJZ E;  2E2J F;  2NVQ F;  5M5X F;  3CQZ F;  3HOU E;  1I50 E;  1I3Q F;  4LK1 E;  5FLM F;  4MEY E;  4A3E E;  1QKL A;  2JA7 E;  3M4O E;  5C4J E;  3H0G E;  3S1M F;  4BY1 E;  3HOX F;  3M3Y E;  3GTJ F;  4A3B E;  1TWH E;  3S1R F;  5IP7 E;  2NVX F;  3EQL E;  3HOV E;  3S14 F;  3S17 E;  3HKZ H;  1EIK A;  5IYB E;  2KRX A;  5FJ8 F;  2JA8 F;  3GTK E;  3HOZ E;  2R7Z E;  5IP9 F;  4A3D E;  4X6A F;  1Y1W E;  3GTM F;  3I4N F;  1I6H F;  1TWG F;  3GTL E;  3HOW E;  4C3I F;  4YFN E;  5D4C E;  3RZD E;  5M3F E;  2WB1 H;  3I4M E;  5M3M E;  2B63 F;  2E2I F;  2JA6 E;  4G7H E;  4BXX E;  5M5W F;  4Y7N F;  4YG2 E;  2R93 E;  4XLP E; 
#chains in the Genus database with same CATH homology
 4G7O E;  2E2H F;  5E18 E;  4LK0 E;  4Q5S E;  4MQ9 E;  3S1Q F;  3GTG F;  5IYC F;  1HQM E;  1SFO F;  3S2D F;  4A3D F;  4A3I F;  5BYH E;  4G7Z E;  5C4X F;  4A3E F;  5TMF E;  1SMY E;  4BY1 F;  4OIP E;  5M5Y F;  2O5J E;  2A6H E;  4YFX E;  3WOD E;  3S17 F;  3HOV F;  3S2H F;  3PO2 F;  4A3J F;  3HOZ F;  3DXJ E;  2WB1 I;  1ZYR E;  4C3H F;  1WCM F;  3PO3 F;  2PPB E;  3S15 F;  5IPL E;  4BBR F;  4GZY E;  2JA5 F;  3I4M F;  1Y1V F;  3HKZ K;  2JA6 F;  4OIQ E;  1TWC F;  4A3G F;  1I6V E;  1R9T F;  2VUM F;  2PMZ K;  4C2M F;  1K83 F;  5D4E E;  3HOU F;  1I50 F;  5C3E F;  5D4D E;  2JA7 F;  3M4O F;  4A93 F;  5C4J F;  3H0G F;  3M3Y F;  4Y52 F;  4YFK E;  4A3B F;  1TWH F;  3H3V G;  4A3C F;  5IP7 F;  4XSX E;  4OIR E;  3K7A F;  4JK1 E;  4BBS F;  5IYB F;  3GTK F;  2R7Z F;  1Y1W F;  3GTL F;  3HOW F;  2BE5 E;  3I4N F;  3S16 F;  4XSZ E;  5M3F F;  3RZD F;  3GTO F;  4QIW K;  5M3M F;  4LLG E;  2R92 F;  4BXX F;  4MEX E;  1YNN K;  3FKI F;  2A68 E;  3RZO F;  2R93 F;  5E17 E;  4KN4 E;  4A3K F;  4A3F F;  2A6E E;  4XLN E;  5TMC E;  2NVT F;  1TWA F;  4OIN E;  4AYB K;  2A69 E;  3GTP F;  2CW0 E;  3GTQ F;  1IW7 E;  4KMU E;  3HOY F;  2NVY F;  2WAQ K;  5C44 F;  2O5I E;  3S1N F;  1TWF F;  4A3L F;  4KN7 E;  4ZH4 E;  1YNJ K;  4A3M F;  4Q4Z E;  2Y0S I;  4BY7 F;  5IYD F;  2YU9 F;  4C3J F;  4OIO E;  2NVQ F;  4LJZ E;  2E2J F;  5M5X F;  3CQZ F;  1I3Q F;  4LK1 E;  5FLM F;  4MEY E;  1QKL A;  3S1M F;  3HOX F;  3GTJ F;  3S1R F;  2NVX F;  3S14 F;  3EQL E;  2KRX A;  5FJ8 F;  2JA8 F;  5IP9 F;  4X6A F;  3GTM F;  1I6H F;  1TWG F;  4C3I F;  4YFN E;  5D4C E;  2B63 F;  2E2I F;  4G7H E;  5M5W F;  4Y7N F;  4YG2 E;  4XLP E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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