5FPFC

Crystal structure of human tankyrase 2 in complex with ta-91
Total Genus 0
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
0
sequence length
46
structure length
46
Chain Sequence
AHSPPGHHSVTGRPSVNGLALAEYVIYRGEQAYPEYLITYQIMRPE

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Design, Synthesis and Evaluation of Novel Dual- Binding Inhibitors of the Tankyrases and Wnt Signalling.
rcsb
molecule tags Transferase
source organism Homo sapiens
molecule keywords TANKYRASE-2
structure length 46
sequence length 46
chains with identical sequence D
ec nomenclature ec 2.4.2.30: NAD(+) ADP-ribosyltransferase.
pdb deposition date 2015-11-30
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1620.50 Alpha Beta 3-Layer(aba) Sandwich YefM-like fold YefM-like fold 5fpfC00
5ADTB 4HMHC 4KZLC 5ADRB 4HLKC 4L32C 4UVPB 4HL5C 4L0BC 4HKNC 4L2FC 4KZUC 4UI3C 4L0IC 4L2GC 4HKIC 4L31C 5ADQB 4HLFC 4UI8C 4L0SC 4L10C 4L2KC 4HLGC 4UI5C 4UI4C 4KZQC 4UI7C 5C5RC 4HKKB 4L0TC 5C5QC 5FPFC 4L0VC 5C5PC 4HLHC 5ADSB 4L09C 4UI6C 4L34C 4L33C 4HLMC
chains in the Genus database with same CATH superfamily
5ADTB 4HMHC 3K33B 4KZLC 2A6QA 3K6QA 4HLKC 5ADRB 4L32C 4UVPB 4HL5C 4L0BC 4HKNC 4L2FC 3CTOA 4ZLXA 4KZUC 4UI3C 4L0IC 2ODKA 4HKIC 4L2GC 4L31C 4ZM0A 5ADQB 3OEIA 4HLFC 4ZM2A 4UI8C 4L0SC 3D55A 2ZIXB 4L10C 4HLGC 4L2KC 4UI5C 4KZQC 4UI4C 4UI7C 5C5RC 4HKKB 4L0TC 5C5QC 3HRYA 3HS2A 3HJ6A 5FPFC 4L0VC 5C5PC 4HLHC 3G5OA 3KH2E 4L09C 5ADSB 4UI6C 4L34C 3OEIE 4L33C 4HLMC
chains in the Genus database with same CATH topology
5ADTB 4HMHC 4KZLC 5ADRB 4HLKC 4L32C 4UVPB 4HL5C 4L0BC 4HKNC 4L2FC 4KZUC 4UI3C 4L0IC 4L2GC 4HKIC 4L31C 5ADQB 4HLFC 4UI8C 4L0SC 2ZIXB 4L10C 4HLGC 4L2KC 4UI5C 4KZQC 4UI4C 4UI7C 5C5RC 4HKKB 4L0TC 5C5QC 3HJ6A 5FPFC 4L0VC 5C5PC 4HLHC 5ADSB 4L09C 4UI6C 4L34C 4L33C 4HLMC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5ADT B;  4HMH C;  4KZL C;  5ADR B;  4HLK C;  4L32 C;  4UVP B;  4HL5 C;  4L0B C;  4HKN C;  4L2F C;  4KZU C;  4UI3 C;  4L0I C;  4L2G C;  4HKI C;  4L31 C;  5ADQ B;  4HLF C;  4UI8 C;  4L0S C;  4L10 C;  4L2K C;  4HLG C;  4UI5 C;  4UI4 C;  4KZQ C;  4UI7 C;  5C5R C;  4HKK B;  4L0T C;  5C5Q C;  5FPF C;  4L0V C;  5C5P C;  4HLH C;  5ADS B;  4L09 C;  4UI6 C;  4L34 C;  4L33 C;  4HLM C; 
#chains in the Genus database with same CATH topology
 5ADT B;  4HMH C;  3K33 B;  4KZL C;  2A6Q A;  3K6Q A;  4HLK C;  5ADR B;  4L32 C;  4UVP B;  4HL5 C;  4L0B C;  4HKN C;  4L2F C;  3CTO A;  4ZLX A;  4KZU C;  4UI3 C;  4L0I C;  2ODK A;  4HKI C;  4L2G C;  4L31 C;  4ZM0 A;  5ADQ B;  3OEI A;  4HLF C;  4ZM2 A;  4UI8 C;  4L0S C;  3D55 A;  2ZIX B;  4L10 C;  4HLG C;  4L2K C;  4UI5 C;  4KZQ C;  4UI4 C;  4UI7 C;  5C5R C;  4HKK B;  4L0T C;  5C5Q C;  3HRY A;  3HS2 A;  3HJ6 A;  5FPF C;  4L0V C;  5C5P C;  4HLH C;  3G5O A;  3KH2 E;  4L09 C;  5ADS B;  4UI6 C;  4L34 C;  3OEI E;  4L33 C;  4HLM C; 
#chains in the Genus database with same CATH homology
 5ADT B;  4HMH C;  4KZL C;  5ADR B;  4HLK C;  4L32 C;  4UVP B;  4HL5 C;  4L0B C;  4HKN C;  4L2F C;  4KZU C;  4UI3 C;  4L0I C;  4L2G C;  4HKI C;  4L31 C;  5ADQ B;  4HLF C;  4UI8 C;  4L0S C;  2ZIX B;  4L10 C;  4HLG C;  4L2K C;  4UI5 C;  4KZQ C;  4UI4 C;  4UI7 C;  5C5R C;  4HKK B;  4L0T C;  5C5Q C;  3HJ6 A;  5FPF C;  4L0V C;  5C5P C;  4HLH C;  5ADS B;  4L09 C;  4UI6 C;  4L34 C;  4L33 C;  4HLM C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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