5FPFC

Crystal structure of human tankyrase 2 in complex with ta-91
Total Genus 0
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
0
sequence length
46
structure length
46
Chain Sequence
AHSPPGHHSVTGRPSVNGLALAEYVIYRGEQAYPEYLITYQIMRPE

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Transferase
source organism Homo sapiens
publication title Design, Synthesis and Evaluation of Novel Dual- Binding Inhibitors of the Tankyrases and Wnt Signalling.
rcsb
molecule keywords TANKYRASE-2
structure length 46
sequence length 46
chains with identical sequence D
ec nomenclature ec 2.4.2.30: NAD(+) ADP-ribosyltransferase.
pdb deposition date 2015-11-30
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1620.50 Alpha Beta 3-Layer(aba) Sandwich YefM-like fold YefM-like fold 5fpfC00
5C5QC 5FPFC 4UI6C 4HLHC 4KZQC 4L10C 4L32C 5ADSB 4HL5C 4KZLC 4UI7C 4L31C 4UVPB 4KZUC 5C5RC 4L0SC 4L0TC 4HKKB 4L0IC 4UI8C 4HLGC 4HLKC 4UI4C 4HLMC 4L33C 4L2KC 5ADTB 5ADRB 4L2GC 4L2FC 5C5PC 4HKNC 4L34C 4UI5C 4HLFC 4L09C 4HKIC 5ADQB 4UI3C 4HMHC 4L0BC 4L0VC
chains in the Genus database with same CATH superfamily
5C5QC 5FPFC 2ODKA 4UI6C 4HLHC 4KZQC 4L10C 4L32C 5ADSB 3OEIE 4HL5C 4KZLC 4UI7C 4L31C 4UVPB 4KZUC 5C5RC 3HS2A 4L0SC 3HJ6A 3G5OA 4L0TC 4HKKB 2A6QA 4L0IC 4UI8C 4HLGC 4HLKC 4UI4C 4HLMC 4L33C 4L2KC 5ADTB 5ADRB 3HRYA 3CTOA 4L2GC 3K6QA 4L2FC 5C5PC 3KH2E 4ZM0A 3K33B 4HKNC 4L34C 3OEIA 4UI5C 4HLFC 3D55A 4L09C 4ZLXA 4HKIC 4ZM2A 5ADQB 4UI3C 4HMHC 4L0BC 4L0VC 2ZIXB
chains in the Genus database with same CATH topology
5C5QC 5FPFC 4UI6C 4HLHC 4KZQC 4L10C 4L32C 5ADSB 4HL5C 4KZLC 4UI7C 4L31C 4UVPB 4KZUC 5C5RC 4L0SC 3HJ6A 4L0TC 4HKKB 4L0IC 4UI8C 4HLGC 4HLKC 4UI4C 4HLMC 4L33C 4L2KC 5ADTB 5ADRB 4L2GC 4L2FC 5C5PC 4HKNC 4L34C 4UI5C 4HLFC 4L09C 4HKIC 5ADQB 4UI3C 4HMHC 4L0BC 4L0VC 2ZIXB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5C5Q C;  5FPF C;  4UI6 C;  4HLH C;  4KZQ C;  4L10 C;  4L32 C;  5ADS B;  4HL5 C;  4KZL C;  4UI7 C;  4L31 C;  4UVP B;  4KZU C;  5C5R C;  4L0S C;  4L0T C;  4HKK B;  4L0I C;  4UI8 C;  4HLG C;  4HLK C;  4UI4 C;  4HLM C;  4L33 C;  4L2K C;  5ADT B;  5ADR B;  4L2G C;  4L2F C;  5C5P C;  4HKN C;  4L34 C;  4UI5 C;  4HLF C;  4L09 C;  4HKI C;  5ADQ B;  4UI3 C;  4HMH C;  4L0B C;  4L0V C; 
#chains in the Genus database with same CATH topology
 5C5Q C;  5FPF C;  2ODK A;  4UI6 C;  4HLH C;  4KZQ C;  4L10 C;  4L32 C;  5ADS B;  3OEI E;  4HL5 C;  4KZL C;  4UI7 C;  4L31 C;  4UVP B;  4KZU C;  5C5R C;  3HS2 A;  4L0S C;  3HJ6 A;  3G5O A;  4L0T C;  4HKK B;  2A6Q A;  4L0I C;  4UI8 C;  4HLG C;  4HLK C;  4UI4 C;  4HLM C;  4L33 C;  4L2K C;  5ADT B;  5ADR B;  3HRY A;  3CTO A;  4L2G C;  3K6Q A;  4L2F C;  5C5P C;  3KH2 E;  4ZM0 A;  3K33 B;  4HKN C;  4L34 C;  3OEI A;  4UI5 C;  4HLF C;  3D55 A;  4L09 C;  4ZLX A;  4HKI C;  4ZM2 A;  5ADQ B;  4UI3 C;  4HMH C;  4L0B C;  4L0V C;  2ZIX B; 
#chains in the Genus database with same CATH homology
 5C5Q C;  5FPF C;  4UI6 C;  4HLH C;  4KZQ C;  4L10 C;  4L32 C;  5ADS B;  4HL5 C;  4KZL C;  4UI7 C;  4L31 C;  4UVP B;  4KZU C;  5C5R C;  4L0S C;  3HJ6 A;  4L0T C;  4HKK B;  4L0I C;  4UI8 C;  4HLG C;  4HLK C;  4UI4 C;  4HLM C;  4L33 C;  4L2K C;  5ADT B;  5ADR B;  4L2G C;  4L2F C;  5C5P C;  4HKN C;  4L34 C;  4UI5 C;  4HLF C;  4L09 C;  4HKI C;  5ADQ B;  4UI3 C;  4HMH C;  4L0B C;  4L0V C;  2ZIX B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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