5IYBF

Human core-pic in the open state
Total Genus 20
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
20
sequence length
86
structure length
86
Chain Sequence
GERPQANQKRITTPYMTKYERARVLGTRALQIAMCAPVMVELEGETDPLLIAMKELKARKIPIIIRRYLPDGSYEDWGVDELIITD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Near-atomic resolution visualization of human transcription promoter opening.
pubmed doi rcsb
molecule tags Transcription, transferase/dna
source organism Homo sapiens
molecule keywords DNA-directed RNA polymerase II subunit RPB1
total genus 20
structure length 86
sequence length 86
ec nomenclature
pdb deposition date 2016-03-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
F PF01192 RNA_pol_Rpb6 RNA polymerase Rpb6
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.940.10 Alpha Beta Alpha-Beta Complex Eukaryotic RPB6 RNA polymerase subunit Eukaryotic RPB6 RNA polymerase subunit 5iybF00
3GTGF 4BXXF 5IPLE 2A6HE 2NVXF 2A69E 4MEYE 4GZYE 4G7OE 4Q4ZE 3HOWF 4X6AF 5C3EF 5D4DE 2WAQK 3S16F 5TMCE 3WODE 4XSXE 3S2DF 5M5WF 4MQ9E 3PO3F 1YNNK 5C44F 3M3YF 3PO2F 2O5JE 5BYHE 4OINE 4A3MF 2E2IF 3S2HF 2JA7F 3I4MF 3GTPF 3S1MF 4LK0E 3K7AF 3GTLF 3RZDF 3GTKF 2R7ZF 4G7HE 2YU9F 3HKZK 2O5IE 4OIQE 4YG2E 4Y7NF 3DXJE 2JA6F 3S14F 4OIRE 4C3IF 3M4OF 4OIOE 3I4NF 1IW7E 3H0GF 4XSZE 3S1QF 5FLMF 4JK1E 2E2HF 5M5YF 4C2MF 3HOVF 1QKLA 4BBRF 2R93F 4A3BF 1WCMF 2PMZK 5IYDF 1SMYE 5D4EE 2A68E 3FKIF 3GTOF 3S1NF 5IP7F 1Y1WF 5C4XF 5M3FF 5D4CE 4BY7F 4A3LF 2CW0E 4XLNE 3S17F 5M3MF 1TWHF 2PPBE 4G7ZE 2B63F 3S15F 4A3JF 4BBSF 4C3JF 4OIPE 3RZOF 1I3QF 4AYBK 3GTMF 1ZYRE 4YFXE 4A3KF 3HOYF 4A3IF 1R9TF 1I6HF 3H3VG 1I6VE 4LLGE 5C4JF 2JA5F 2BE5E 4BY1F 3S1RF 2NVQF 1SFOF 4MEXE 1TWCF 3CQZF 5IYBF 4A3GF 2R92F 5IP9F 4LJZE 3HOZF 4A93F 1K83F 1I50F 4YFNE 3GTQF 2NVTF 4ZH4E 5E17E 4LK1E 4Y52F 5M5XF 3GTJF 2Y0SI 4A3EF 2VUMF 4KMUE 1TWAF 4KN4E 4Q5SE 1YNJK 5IYCF 1TWGF 2WB1I 5TMFE 4A3FF 4C3HF 3HOXF 4A3CF 2NVYF 4XLPE 1Y1VF 4YFKE 3EQLE 2A6EE 1TWFF 5E18E 3HOUF 2E2JF 2JA8F 4A3DF 1HQME 5FJ8F 4KN7E
chains in the Genus database with same CATH superfamily
3GTGF 4BXXF 5IPLE 2A6HE 2NVXF 2A69E 4MEYE 4Y7NE 4G7OE 4GZYE 4Q4ZE 2JA6E 3HOWF 3S14E 4X6AF 4C3IE 5C3EF 3M4OE 5D4DE 3I4NE 3H0GE 3S1QE 5FLME 2WAQK 3S16F 5TMCE 3WODE 2E2HE 4XSXE 3S2DF 5M5YE 5M5WF 4MQ9E 3PO3F 4C2ME 1YNNK 4QIWH 4BBRE 3HOVE 2R93E 5C44F 1WCME 4A3BE 5IYBE 3M3YF 3PO2F 5IYDE 2O5JE 5BYHE 3FKIE 4OINE 3GTOE 3S1NE 5IP7E 4A3MF 1Y1WE 5C4XE 2E2IF 3S2HF 5M3FE 2JA7F 3I4MF 3GTPF 3S1MF 4LK0E 3K7AF 4A3LE 3S17E 4BY7E 3GTLF 3RZDF 5M3ME 3GTKF 1TWHE 2R7ZF 4G7HE 3S15E 2YU9F 2B63E 3HKZK 2O5IE 4A3JE 4BBSE 4C3JE 3RZOE 4OIQE 4YG2E 1I3QE 4Y7NF 3GTME 3DXJE 2JA6F 3S14F 4A3KE 4OIRE 4C3IF 3HOYE 4A3IE 3M4OF 1R9TE 3HKZH 4OIOE 1I6HE 3I4NF 1IW7E 3H0GF 4XSZE 5C4JE 2JA5E 5FLMF 3H3VF 4JK1E 3S1QF 2E2HF 4BY1E 5M5YF 3S1RE 4A3DE 2NVQE 4C2MF 1SFOE 1TWCE 3CQZE 3HOVF 1QKLA 4BBRF 2R93F 4A3GE 2R92E 5IP9E 1WCMF 2PMZK 4A3BF 2WAQH 3HOZE 1K83E 4A93E 5IYDF 1I50E 1SMYE 2A68E 3FKIF 5D4EE 2NVTE 3GTOF 3GTQE 5IP7F 3S1NF 1Y1WF 5C4XF 4Y52E 5M5XE 5M3FF 5D4CE 3GTJE 4A3EE 1DZFA 2VUME 4BY7F 4A3LF 2CW0E 4XLNE 3S17F 1TWAE 5M3MF 1TWHF 2PPBE 4G7ZE 2B63F 3S15F 4A3JF 4BBSF 5IYCE 4OIPE 1TWGE 4C3JF 4A3FE 3RZOF 4C3HE 1I3QF 3HOXE 4AYBK 3GTMF 4A3CE 1ZYRE 4YFXE 2NVYE 4A3KF 1Y1VE 3HOYF 4A3IF 1TWFE 1R9TF 3HOUE 1I6HF 3H3VG 1I6VE 4LLGE 5C4JF 2E2JE 2BE5E 2JA5F 2JA8E 5FJ8E 4BY1F 3S1RF 2NVQF 1SFOF 4MEXE 1TWCF 3CQZF 5IYBF 3GTGE 4BXXE 4A3GF 2NVXE 5IP9F 2R92F 4LJZE 3HOZF 4A93F 1K83F 3HOWE 1I50F 4YFNE 4X6AE 3GTQF 2NVTF 5C3EE 4ZH4E 5E17E 4LK1E 4QIWK 4Y52F 5M5XF 2KRXA 2PMZH 3GTJF 2Y0SI 4A3EF 3S16E 2VUMF 3S2DE 4KMUE 1TWAF 4KN4E 5M5WE 3PO3E 1EIKA 4Q5SE 1YNJK 5IYCF 1TWGF 2WB1I 5TMFE 5C44E 4A3FF 4C3HF 3M3YE 3HOXF 3PO2E 4A3CF 2NVYF 2Y0SH 1Y1VF 4XLPE 4A3ME 4YFKE 2E2IE 3S2HE 2JA7E 3EQLE 3I4ME 1TWFF 2A6EE 5E18E 3HOUF 3GTPE 3S1ME 3K7AE 4AYBH 2E2JF 2JA8F 3GTLE 3RZDE 1HQME 2WB1H 5FJ8F 2R7ZE 3GTKE 4A3DF 4KN7E 2YU9E
chains in the Genus database with same CATH topology
3GTGF 4BXXF 5IPLE 2A6HE 2NVXF 2A69E 4MEYE 4GZYE 4G7OE 4Q4ZE 3HOWF 4X6AF 5C3EF 5D4DE 2WAQK 3S16F 5TMCE 3WODE 4XSXE 3S2DF 5M5WF 4MQ9E 3PO3F 1YNNK 5C44F 3M3YF 3PO2F 2O5JE 5BYHE 4OINE 4A3MF 2E2IF 3S2HF 2JA7F 3I4MF 3GTPF 3S1MF 4LK0E 3K7AF 3GTLF 3RZDF 3GTKF 2R7ZF 4G7HE 2YU9F 3HKZK 2O5IE 4OIQE 4YG2E 4Y7NF 3DXJE 2JA6F 3S14F 4OIRE 4C3IF 3M4OF 4OIOE 3I4NF 1IW7E 3H0GF 4XSZE 3S1QF 5FLMF 4JK1E 2E2HF 5M5YF 4C2MF 3HOVF 1QKLA 4BBRF 2R93F 4A3BF 1WCMF 2PMZK 5IYDF 1SMYE 5D4EE 2A68E 3FKIF 3GTOF 3S1NF 5IP7F 1Y1WF 5C4XF 5M3FF 5D4CE 4BY7F 4A3LF 2CW0E 4XLNE 3S17F 5M3MF 1TWHF 2PPBE 4G7ZE 2B63F 3S15F 4A3JF 4BBSF 4C3JF 4OIPE 3RZOF 1I3QF 4AYBK 3GTMF 1ZYRE 4YFXE 4A3KF 3HOYF 4A3IF 1R9TF 1I6HF 3H3VG 1I6VE 4LLGE 5C4JF 2JA5F 2BE5E 4BY1F 3S1RF 2NVQF 1SFOF 4MEXE 1TWCF 3CQZF 5IYBF 4A3GF 2R92F 5IP9F 4LJZE 3HOZF 4A93F 1K83F 1I50F 4YFNE 3GTQF 2NVTF 4ZH4E 5E17E 4LK1E 4QIWK 4Y52F 5M5XF 2KRXA 3GTJF 2Y0SI 4A3EF 2VUMF 4KMUE 1TWAF 4KN4E 4Q5SE 1YNJK 5IYCF 1TWGF 2WB1I 5TMFE 4A3FF 4C3HF 3HOXF 4A3CF 2NVYF 4XLPE 1Y1VF 4YFKE 3EQLE 2A6EE 1TWFF 5E18E 3HOUF 2E2JF 2JA8F 4A3DF 1HQME 5FJ8F 4KN7E
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3GTG F;  4BXX F;  5IPL E;  2A6H E;  2NVX F;  2A69 E;  4MEY E;  4GZY E;  4G7O E;  4Q4Z E;  3HOW F;  4X6A F;  5C3E F;  5D4D E;  2WAQ K;  3S16 F;  5TMC E;  3WOD E;  4XSX E;  3S2D F;  5M5W F;  4MQ9 E;  3PO3 F;  1YNN K;  5C44 F;  3M3Y F;  3PO2 F;  2O5J E;  5BYH E;  4OIN E;  4A3M F;  2E2I F;  3S2H F;  2JA7 F;  3I4M F;  3GTP F;  3S1M F;  4LK0 E;  3K7A F;  3GTL F;  3RZD F;  3GTK F;  2R7Z F;  4G7H E;  2YU9 F;  3HKZ K;  2O5I E;  4OIQ E;  4YG2 E;  4Y7N F;  3DXJ E;  2JA6 F;  3S14 F;  4OIR E;  4C3I F;  3M4O F;  4OIO E;  3I4N F;  1IW7 E;  3H0G F;  4XSZ E;  3S1Q F;  5FLM F;  4JK1 E;  2E2H F;  5M5Y F;  4C2M F;  3HOV F;  1QKL A;  4BBR F;  2R93 F;  4A3B F;  1WCM F;  2PMZ K;  5IYD F;  1SMY E;  5D4E E;  2A68 E;  3FKI F;  3GTO F;  3S1N F;  5IP7 F;  1Y1W F;  5C4X F;  5M3F F;  5D4C E;  4BY7 F;  4A3L F;  2CW0 E;  4XLN E;  3S17 F;  5M3M F;  1TWH F;  2PPB E;  4G7Z E;  2B63 F;  3S15 F;  4A3J F;  4BBS F;  4C3J F;  4OIP E;  3RZO F;  1I3Q F;  4AYB K;  3GTM F;  1ZYR E;  4YFX E;  4A3K F;  3HOY F;  4A3I F;  1R9T F;  1I6H F;  3H3V G;  1I6V E;  4LLG E;  5C4J F;  2JA5 F;  2BE5 E;  4BY1 F;  3S1R F;  2NVQ F;  1SFO F;  4MEX E;  1TWC F;  3CQZ F;  5IYB F;  4A3G F;  2R92 F;  5IP9 F;  4LJZ E;  3HOZ F;  4A93 F;  1K83 F;  1I50 F;  4YFN E;  3GTQ F;  2NVT F;  4ZH4 E;  5E17 E;  4LK1 E;  4Y52 F;  5M5X F;  3GTJ F;  2Y0S I;  4A3E F;  2VUM F;  4KMU E;  1TWA F;  4KN4 E;  4Q5S E;  1YNJ K;  5IYC F;  1TWG F;  2WB1 I;  5TMF E;  4A3F F;  4C3H F;  3HOX F;  4A3C F;  2NVY F;  4XLP E;  1Y1V F;  4YFK E;  3EQL E;  2A6E E;  1TWF F;  5E18 E;  3HOU F;  2E2J F;  2JA8 F;  4A3D F;  1HQM E;  5FJ8 F;  4KN7 E; 
#chains in the Genus database with same CATH topology
 3GTG F;  4BXX F;  5IPL E;  2A6H E;  2NVX F;  2A69 E;  4MEY E;  4Y7N E;  4G7O E;  4GZY E;  4Q4Z E;  2JA6 E;  3HOW F;  3S14 E;  4X6A F;  4C3I E;  5C3E F;  3M4O E;  5D4D E;  3I4N E;  3H0G E;  3S1Q E;  5FLM E;  2WAQ K;  3S16 F;  5TMC E;  3WOD E;  2E2H E;  4XSX E;  3S2D F;  5M5Y E;  5M5W F;  4MQ9 E;  3PO3 F;  4C2M E;  1YNN K;  4QIW H;  4BBR E;  3HOV E;  2R93 E;  5C44 F;  1WCM E;  4A3B E;  5IYB E;  3M3Y F;  3PO2 F;  5IYD E;  2O5J E;  5BYH E;  3FKI E;  4OIN E;  3GTO E;  3S1N E;  5IP7 E;  4A3M F;  1Y1W E;  5C4X E;  2E2I F;  3S2H F;  5M3F E;  2JA7 F;  3I4M F;  3GTP F;  3S1M F;  4LK0 E;  3K7A F;  4A3L E;  3S17 E;  4BY7 E;  3GTL F;  3RZD F;  5M3M E;  3GTK F;  1TWH E;  2R7Z F;  4G7H E;  3S15 E;  2YU9 F;  2B63 E;  3HKZ K;  2O5I E;  4A3J E;  4BBS E;  4C3J E;  3RZO E;  4OIQ E;  4YG2 E;  1I3Q E;  4Y7N F;  3GTM E;  3DXJ E;  2JA6 F;  3S14 F;  4A3K E;  4OIR E;  4C3I F;  3HOY E;  4A3I E;  3M4O F;  1R9T E;  3HKZ H;  4OIO E;  1I6H E;  3I4N F;  1IW7 E;  3H0G F;  4XSZ E;  5C4J E;  2JA5 E;  5FLM F;  3H3V F;  4JK1 E;  3S1Q F;  2E2H F;  4BY1 E;  5M5Y F;  3S1R E;  4A3D E;  2NVQ E;  4C2M F;  1SFO E;  1TWC E;  3CQZ E;  3HOV F;  1QKL A;  4BBR F;  2R93 F;  4A3G E;  2R92 E;  5IP9 E;  1WCM F;  2PMZ K;  4A3B F;  2WAQ H;  3HOZ E;  1K83 E;  4A93 E;  5IYD F;  1I50 E;  1SMY E;  2A68 E;  3FKI F;  5D4E E;  2NVT E;  3GTO F;  3GTQ E;  5IP7 F;  3S1N F;  1Y1W F;  5C4X F;  4Y52 E;  5M5X E;  5M3F F;  5D4C E;  3GTJ E;  4A3E E;  1DZF A;  2VUM E;  4BY7 F;  4A3L F;  2CW0 E;  4XLN E;  3S17 F;  1TWA E;  5M3M F;  1TWH F;  2PPB E;  4G7Z E;  2B63 F;  3S15 F;  4A3J F;  4BBS F;  5IYC E;  4OIP E;  1TWG E;  4C3J F;  4A3F E;  3RZO F;  4C3H E;  1I3Q F;  3HOX E;  4AYB K;  3GTM F;  4A3C E;  1ZYR E;  4YFX E;  2NVY E;  4A3K F;  1Y1V E;  3HOY F;  4A3I F;  1TWF E;  1R9T F;  3HOU E;  1I6H F;  3H3V G;  1I6V E;  4LLG E;  5C4J F;  2E2J E;  2BE5 E;  2JA5 F;  2JA8 E;  5FJ8 E;  4BY1 F;  3S1R F;  2NVQ F;  1SFO F;  4MEX E;  1TWC F;  3CQZ F;  5IYB F;  3GTG E;  4BXX E;  4A3G F;  2NVX E;  5IP9 F;  2R92 F;  4LJZ E;  3HOZ F;  4A93 F;  1K83 F;  3HOW E;  1I50 F;  4YFN E;  4X6A E;  3GTQ F;  2NVT F;  5C3E E;  4ZH4 E;  5E17 E;  4LK1 E;  4QIW K;  4Y52 F;  5M5X F;  2KRX A;  2PMZ H;  3GTJ F;  2Y0S I;  4A3E F;  3S16 E;  2VUM F;  3S2D E;  4KMU E;  1TWA F;  4KN4 E;  5M5W E;  3PO3 E;  1EIK A;  4Q5S E;  1YNJ K;  5IYC F;  1TWG F;  2WB1 I;  5TMF E;  5C44 E;  4A3F F;  4C3H F;  3M3Y E;  3HOX F;  3PO2 E;  4A3C F;  2NVY F;  2Y0S H;  1Y1V F;  4XLP E;  4A3M E;  4YFK E;  2E2I E;  3S2H E;  2JA7 E;  3EQL E;  3I4M E;  1TWF F;  2A6E E;  5E18 E;  3HOU F;  3GTP E;  3S1M E;  3K7A E;  4AYB H;  2E2J F;  2JA8 F;  3GTL E;  3RZD E;  1HQM E;  2WB1 H;  5FJ8 F;  2R7Z E;  3GTK E;  4A3D F;  4KN7 E;  2YU9 E; 
#chains in the Genus database with same CATH homology
 3GTG F;  4BXX F;  5IPL E;  2A6H E;  2NVX F;  2A69 E;  4MEY E;  4GZY E;  4G7O E;  4Q4Z E;  3HOW F;  4X6A F;  5C3E F;  5D4D E;  2WAQ K;  3S16 F;  5TMC E;  3WOD E;  4XSX E;  3S2D F;  5M5W F;  4MQ9 E;  3PO3 F;  1YNN K;  5C44 F;  3M3Y F;  3PO2 F;  2O5J E;  5BYH E;  4OIN E;  4A3M F;  2E2I F;  3S2H F;  2JA7 F;  3I4M F;  3GTP F;  3S1M F;  4LK0 E;  3K7A F;  3GTL F;  3RZD F;  3GTK F;  2R7Z F;  4G7H E;  2YU9 F;  3HKZ K;  2O5I E;  4OIQ E;  4YG2 E;  4Y7N F;  3DXJ E;  2JA6 F;  3S14 F;  4OIR E;  4C3I F;  3M4O F;  4OIO E;  3I4N F;  1IW7 E;  3H0G F;  4XSZ E;  3S1Q F;  5FLM F;  4JK1 E;  2E2H F;  5M5Y F;  4C2M F;  3HOV F;  1QKL A;  4BBR F;  2R93 F;  4A3B F;  1WCM F;  2PMZ K;  5IYD F;  1SMY E;  5D4E E;  2A68 E;  3FKI F;  3GTO F;  3S1N F;  5IP7 F;  1Y1W F;  5C4X F;  5M3F F;  5D4C E;  4BY7 F;  4A3L F;  2CW0 E;  4XLN E;  3S17 F;  5M3M F;  1TWH F;  2PPB E;  4G7Z E;  2B63 F;  3S15 F;  4A3J F;  4BBS F;  4C3J F;  4OIP E;  3RZO F;  1I3Q F;  4AYB K;  3GTM F;  1ZYR E;  4YFX E;  4A3K F;  3HOY F;  4A3I F;  1R9T F;  1I6H F;  3H3V G;  1I6V E;  4LLG E;  5C4J F;  2JA5 F;  2BE5 E;  4BY1 F;  3S1R F;  2NVQ F;  1SFO F;  4MEX E;  1TWC F;  3CQZ F;  5IYB F;  4A3G F;  2R92 F;  5IP9 F;  4LJZ E;  3HOZ F;  4A93 F;  1K83 F;  1I50 F;  4YFN E;  3GTQ F;  2NVT F;  4ZH4 E;  5E17 E;  4LK1 E;  4QIW K;  4Y52 F;  5M5X F;  2KRX A;  3GTJ F;  2Y0S I;  4A3E F;  2VUM F;  4KMU E;  1TWA F;  4KN4 E;  4Q5S E;  1YNJ K;  5IYC F;  1TWG F;  2WB1 I;  5TMF E;  4A3F F;  4C3H F;  3HOX F;  4A3C F;  2NVY F;  4XLP E;  1Y1V F;  4YFK E;  3EQL E;  2A6E E;  1TWF F;  5E18 E;  3HOU F;  2E2J F;  2JA8 F;  4A3D F;  1HQM E;  5FJ8 F;  4KN7 E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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