5JB7A

A simplified bpti variant containing 24 alanines out of 58 residues
Total Genus 9
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
9
sequence length
56
structure length
56
Chain Sequence
RPAFCLEAPYAGPGAAAIIRYFYNAAAGAAQAFVYGGVAAKRNNFASAAAALAACA
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Crystal structures of highly simplified BPTIs provide insights into hydration-driven increase of unfolding enthalpy
pubmed doi rcsb
molecule tags Hydrolase inhibitor
source organism Bos taurus
molecule keywords Pancreatic trypsin inhibitor
total genus 9
structure length 56
sequence length 56
chains with identical sequence B, C
ec nomenclature
pdb deposition date 2016-04-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00014 Kunitz_BPTI Kunitz/Bovine pancreatic trypsin inhibitor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.410.10 Few Secondary Structures Irregular Factor Xa Inhibitor Pancreatic trypsin inhibitor Kunitz domain 5jb7A00
1OA65 1QLQA 2DDIA 3BTKI 3TGKI 3AUHA 3BTTI 1KUNA 1K6UA 1BIKA 2M01A 3OFWA 1TCPA 3CI7A 1NAGA 1YLDB 3P92E 1DTXA 3UOUB 1DENA 1BTHP 1TFXC 1YKTB 5PTIA 4BNRI 5JB7A 1EJMB 2FTLI 3TGJI 1T7CB 2J6DA 2KCRA 1CO7I 3BTQI 5JB6A 4WWYC 3AUDA 1AALA 3U1JE 9PTIA 3M7QB 1LD6A 1UUAA 1ADZA 3OTJI 4U32X 1BZ5A 4Y0ZI 2LFLA 4NTXB 2FI5I 1P2II 1FAKI 1TPAI 2ODYE 2IJOI 3BTMI 1CBWD 4Y10I 1BRBI 4NTYB 3BTHI 3BTWI 1D0DA 4U30W 1TAPA 4PTIA 4ISOB 4BD9B 6PTIA 1KTHA 3LDJA 1F5RI 3AUEA 3TGII 2KNTA 1Y62A 1FANA 1BZXI 4ISLB 4DG4C 2KAII 3BTEI 3L3TE 1P2OB 1SHPA 5JB4A 1KIGI 1G6XA 1KNTA 3BTGI 1TOCR 4TPII 1MTND 1EAWB 7PTIA 1T8MB 2ZVXA 2FTMB 2W8XA 3GYMI 3LDMA 1DEMA 3AUGA 4Y11I 2M99A 1OA55 3WNYA 1BPIA 3L33E 1P2KI 2CA7A 2TPII 2RA3C 3BYBA 2PTCI 1JC6A 1FY8I 1JV8A 3LDIA 1CA0D 8PTIA 1BHCA 1AAPA 1ZR0B 2UUYB 3BTFI 1ZJDB 5JB5A 2HEXA 1BTIA 4ISNB 1D0DB 1IRHA 2LFKA 2R9PE 3BTDI 1P2MB 3AUBA 3FP6I 4Y0YI 1BF0A 2UUXA 1P2QB 1UUBA 3FP8I 1P2JI 1P2NB 2FI3I 3T62D 1YLCB 4NTWB 1F7ZI 3AUCA 2JOTA 3P95E 1JV9A 5C67C 1LD5A 1TAWB 3AUIA 1T8LB 1PITA 1BPTA 4WXVC 2FI4I 1BUNB 2ZJXA 1BRCI 1DTKA 1YC0I 3D65I 1T8NB 4BQDA 4DTGK 1T8OB 2DDJA 3UIRC 2TGPI 3FP7J 3TPII 1B0CA
chains in the Genus database with same CATH superfamily
1OA65 1QLQA 2DDIA 3BTKI 3TGKI 3AUHA 3BTTI 1KUNA 1K6UA 1BIKA 2M01A 3OFWA 1TCPA 3CI7A 1NAGA 1YLDB 3P92E 1DTXA 3UOUB 1DENA 1BTHP 1TFXC 1YKTB 5PTIA 4BNRI 5JB7A 1EJMB 2FTLI 3TGJI 1T7CB 2J6DA 2KCRA 1CO7I 3BTQI 5JB6A 4WWYC 3AUDA 1AALA 3U1JE 9PTIA 3M7QB 1LD6A 1UUAA 1ADZA 3OTJI 4U32X 1BZ5A 4Y0ZI 2LFLA 4NTXB 2FI5I 1P2II 1FAKI 1TPAI 2ODYE 2IJOI 3BTMI 1CBWD 4Y10I 1BRBI 4NTYB 3BTHI 3BTWI 1D0DA 4U30W 1TAPA 4PTIA 4ISOB 4BD9B 6PTIA 1KTHA 3LDJA 1F5RI 3AUEA 3TGII 2KNTA 1Y62A 1FANA 1BZXI 4ISLB 4DG4C 2KAII 3BTEI 3L3TE 1P2OB 1SHPA 5JB4A 1KIGI 1G6XA 1KNTA 3BTGI 1TOCR 4TPII 1MTND 1EAWB 7PTIA 1T8MB 2ZVXA 2FTMB 2W8XA 3GYMI 3LDMA 1DEMA 3AUGA 4Y11I 2M99A 1OA55 3WNYA 1BPIA 3L33E 1P2KI 2CA7A 2TPII 2RA3C 3BYBA 2PTCI 1JC6A 1FY8I 1JV8A 3LDIA 1CA0D 8PTIA 1BHCA 1AAPA 1ZR0B 2UUYB 3BTFI 1ZJDB 5JB5A 2HEXA 1BTIA 4ISNB 1D0DB 1IRHA 2LFKA 2R9PE 3BTDI 1P2MB 3AUBA 3FP6I 4Y0YI 1BF0A 2UUXA 1P2QB 1UUBA 3FP8I 1P2JI 1P2NB 2FI3I 3T62D 1YLCB 4NTWB 1F7ZI 3AUCA 2JOTA 3P95E 1JV9A 5C67C 1LD5A 1TAWB 3AUIA 1T8LB 1PITA 1BPTA 4WXVC 2FI4I 1BUNB 2ZJXA 1BRCI 1DTKA 1YC0I 3D65I 1T8NB 4BQDA 4DTGK 1T8OB 2DDJA 3UIRC 2TGPI 3FP7J 3TPII 1B0CA
chains in the Genus database with same CATH topology
1OA65 1QLQA 2DDIA 3BTKI 3TGKI 3AUHA 3BTTI 1KUNA 1K6UA 1BIKA 2M01A 3OFWA 1TCPA 3CI7A 1NAGA 1YLDB 3P92E 1DTXA 3UOUB 1DENA 1BTHP 1TFXC 1YKTB 5PTIA 4BNRI 5JB7A 1EJMB 2FTLI 3TGJI 1T7CB 2J6DA 2KCRA 1CO7I 3BTQI 5JB6A 4WWYC 3AUDA 1AALA 3U1JE 9PTIA 3M7QB 1LD6A 1UUAA 1ADZA 3OTJI 4U32X 1BZ5A 4Y0ZI 2LFLA 4NTXB 2FI5I 1P2II 1FAKI 1TPAI 2ODYE 2IJOI 3BTMI 1CBWD 4Y10I 1BRBI 4NTYB 3BTHI 3BTWI 1D0DA 4U30W 1TAPA 4PTIA 4ISOB 4BD9B 6PTIA 1KTHA 3LDJA 1F5RI 3AUEA 3TGII 2KNTA 1Y62A 1FANA 1BZXI 4ISLB 4DG4C 2KAII 3BTEI 3L3TE 1P2OB 1SHPA 5JB4A 1KIGI 1G6XA 1KNTA 3BTGI 1TOCR 4TPII 1MTND 1EAWB 7PTIA 1T8MB 2ZVXA 2FTMB 2W8XA 3GYMI 3LDMA 1DEMA 3AUGA 4Y11I 2M99A 1OA55 3WNYA 1BPIA 3L33E 1P2KI 2CA7A 2TPII 2RA3C 3BYBA 2PTCI 1JC6A 1FY8I 1JV8A 3LDIA 1CA0D 8PTIA 1BHCA 1AAPA 1ZR0B 2UUYB 3BTFI 1ZJDB 5JB5A 2HEXA 1BTIA 4ISNB 1D0DB 1IRHA 2LFKA 2R9PE 3BTDI 1P2MB 3AUBA 3FP6I 4Y0YI 1BF0A 2UUXA 1P2QB 1UUBA 3FP8I 1P2JI 1P2NB 2FI3I 3T62D 1YLCB 4NTWB 1F7ZI 3AUCA 2JOTA 3P95E 1JV9A 5C67C 1LD5A 1TAWB 3AUIA 1T8LB 1PITA 1BPTA 4WXVC 2FI4I 1BUNB 2ZJXA 1BRCI 1DTKA 1YC0I 3D65I 1T8NB 4BQDA 4DTGK 1T8OB 2DDJA 3UIRC 2TGPI 3FP7J 3TPII 1B0CA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1OA6 5;  1QLQ A;  2DDI A;  3BTK I;  3TGK I;  3AUH A;  3BTT I;  1KUN A;  1K6U A;  1BIK A;  2M01 A;  3OFW A;  1TCP A;  3CI7 A;  1NAG A;  1YLD B;  3P92 E;  1DTX A;  3UOU B;  1DEN A;  1BTH P;  1TFX C;  1YKT B;  5PTI A;  4BNR I;  5JB7 A;  1EJM B;  2FTL I;  3TGJ I;  1T7C B;  2J6D A;  2KCR A;  1CO7 I;  3BTQ I;  5JB6 A;  4WWY C;  3AUD A;  1AAL A;  3U1J E;  9PTI A;  3M7Q B;  1LD6 A;  1UUA A;  1ADZ A;  3OTJ I;  4U32 X;  1BZ5 A;  4Y0Z I;  2LFL A;  4NTX B;  2FI5 I;  1P2I I;  1FAK I;  1TPA I;  2ODY E;  2IJO I;  3BTM I;  1CBW D;  4Y10 I;  1BRB I;  4NTY B;  3BTH I;  3BTW I;  1D0D A;  4U30 W;  1TAP A;  4PTI A;  4ISO B;  4BD9 B;  6PTI A;  1KTH A;  3LDJ A;  1F5R I;  3AUE A;  3TGI I;  2KNT A;  1Y62 A;  1FAN A;  1BZX I;  4ISL B;  4DG4 C;  2KAI I;  3BTE I;  3L3T E;  1P2O B;  1SHP A;  5JB4 A;  1KIG I;  1G6X A;  1KNT A;  3BTG I;  1TOC R;  4TPI I;  1MTN D;  1EAW B;  7PTI A;  1T8M B;  2ZVX A;  2FTM B;  2W8X A;  3GYM I;  3LDM A;  1DEM A;  3AUG A;  4Y11 I;  2M99 A;  1OA5 5;  3WNY A;  1BPI A;  3L33 E;  1P2K I;  2CA7 A;  2TPI I;  2RA3 C;  3BYB A;  2PTC I;  1JC6 A;  1FY8 I;  1JV8 A;  3LDI A;  1CA0 D;  8PTI A;  1BHC A;  1AAP A;  1ZR0 B;  2UUY B;  3BTF I;  1ZJD B;  5JB5 A;  2HEX A;  1BTI A;  4ISN B;  1D0D B;  1IRH A;  2LFK A;  2R9P E;  3BTD I;  1P2M B;  3AUB A;  3FP6 I;  4Y0Y I;  1BF0 A;  2UUX A;  1P2Q B;  1UUB A;  3FP8 I;  1P2J I;  1P2N B;  2FI3 I;  3T62 D;  1YLC B;  4NTW B;  1F7Z I;  3AUC A;  2JOT A;  3P95 E;  1JV9 A;  5C67 C;  1LD5 A;  1TAW B;  3AUI A;  1T8L B;  1PIT A;  1BPT A;  4WXV C;  2FI4 I;  1BUN B;  2ZJX A;  1BRC I;  1DTK A;  1YC0 I;  3D65 I;  1T8N B;  4BQD A;  4DTG K;  1T8O B;  2DDJ A;  3UIR C;  2TGP I;  3FP7 J;  3TPI I;  1B0C A; 
#chains in the Genus database with same CATH topology
 1OA6 5;  1QLQ A;  2DDI A;  3BTK I;  3TGK I;  3AUH A;  3BTT I;  1KUN A;  1K6U A;  1BIK A;  2M01 A;  3OFW A;  1TCP A;  3CI7 A;  1NAG A;  1YLD B;  3P92 E;  1DTX A;  3UOU B;  1DEN A;  1BTH P;  1TFX C;  1YKT B;  5PTI A;  4BNR I;  5JB7 A;  1EJM B;  2FTL I;  3TGJ I;  1T7C B;  2J6D A;  2KCR A;  1CO7 I;  3BTQ I;  5JB6 A;  4WWY C;  3AUD A;  1AAL A;  3U1J E;  9PTI A;  3M7Q B;  1LD6 A;  1UUA A;  1ADZ A;  3OTJ I;  4U32 X;  1BZ5 A;  4Y0Z I;  2LFL A;  4NTX B;  2FI5 I;  1P2I I;  1FAK I;  1TPA I;  2ODY E;  2IJO I;  3BTM I;  1CBW D;  4Y10 I;  1BRB I;  4NTY B;  3BTH I;  3BTW I;  1D0D A;  4U30 W;  1TAP A;  4PTI A;  4ISO B;  4BD9 B;  6PTI A;  1KTH A;  3LDJ A;  1F5R I;  3AUE A;  3TGI I;  2KNT A;  1Y62 A;  1FAN A;  1BZX I;  4ISL B;  4DG4 C;  2KAI I;  3BTE I;  3L3T E;  1P2O B;  1SHP A;  5JB4 A;  1KIG I;  1G6X A;  1KNT A;  3BTG I;  1TOC R;  4TPI I;  1MTN D;  1EAW B;  7PTI A;  1T8M B;  2ZVX A;  2FTM B;  2W8X A;  3GYM I;  3LDM A;  1DEM A;  3AUG A;  4Y11 I;  2M99 A;  1OA5 5;  3WNY A;  1BPI A;  3L33 E;  1P2K I;  2CA7 A;  2TPI I;  2RA3 C;  3BYB A;  2PTC I;  1JC6 A;  1FY8 I;  1JV8 A;  3LDI A;  1CA0 D;  8PTI A;  1BHC A;  1AAP A;  1ZR0 B;  2UUY B;  3BTF I;  1ZJD B;  5JB5 A;  2HEX A;  1BTI A;  4ISN B;  1D0D B;  1IRH A;  2LFK A;  2R9P E;  3BTD I;  1P2M B;  3AUB A;  3FP6 I;  4Y0Y I;  1BF0 A;  2UUX A;  1P2Q B;  1UUB A;  3FP8 I;  1P2J I;  1P2N B;  2FI3 I;  3T62 D;  1YLC B;  4NTW B;  1F7Z I;  3AUC A;  2JOT A;  3P95 E;  1JV9 A;  5C67 C;  1LD5 A;  1TAW B;  3AUI A;  1T8L B;  1PIT A;  1BPT A;  4WXV C;  2FI4 I;  1BUN B;  2ZJX A;  1BRC I;  1DTK A;  1YC0 I;  3D65 I;  1T8N B;  4BQD A;  4DTG K;  1T8O B;  2DDJ A;  3UIR C;  2TGP I;  3FP7 J;  3TPI I;  1B0C A; 
#chains in the Genus database with same CATH homology
 1OA6 5;  1QLQ A;  2DDI A;  3BTK I;  3TGK I;  3AUH A;  3BTT I;  1KUN A;  1K6U A;  1BIK A;  2M01 A;  3OFW A;  1TCP A;  3CI7 A;  1NAG A;  1YLD B;  3P92 E;  1DTX A;  3UOU B;  1DEN A;  1BTH P;  1TFX C;  1YKT B;  5PTI A;  4BNR I;  5JB7 A;  1EJM B;  2FTL I;  3TGJ I;  1T7C B;  2J6D A;  2KCR A;  1CO7 I;  3BTQ I;  5JB6 A;  4WWY C;  3AUD A;  1AAL A;  3U1J E;  9PTI A;  3M7Q B;  1LD6 A;  1UUA A;  1ADZ A;  3OTJ I;  4U32 X;  1BZ5 A;  4Y0Z I;  2LFL A;  4NTX B;  2FI5 I;  1P2I I;  1FAK I;  1TPA I;  2ODY E;  2IJO I;  3BTM I;  1CBW D;  4Y10 I;  1BRB I;  4NTY B;  3BTH I;  3BTW I;  1D0D A;  4U30 W;  1TAP A;  4PTI A;  4ISO B;  4BD9 B;  6PTI A;  1KTH A;  3LDJ A;  1F5R I;  3AUE A;  3TGI I;  2KNT A;  1Y62 A;  1FAN A;  1BZX I;  4ISL B;  4DG4 C;  2KAI I;  3BTE I;  3L3T E;  1P2O B;  1SHP A;  5JB4 A;  1KIG I;  1G6X A;  1KNT A;  3BTG I;  1TOC R;  4TPI I;  1MTN D;  1EAW B;  7PTI A;  1T8M B;  2ZVX A;  2FTM B;  2W8X A;  3GYM I;  3LDM A;  1DEM A;  3AUG A;  4Y11 I;  2M99 A;  1OA5 5;  3WNY A;  1BPI A;  3L33 E;  1P2K I;  2CA7 A;  2TPI I;  2RA3 C;  3BYB A;  2PTC I;  1JC6 A;  1FY8 I;  1JV8 A;  3LDI A;  1CA0 D;  8PTI A;  1BHC A;  1AAP A;  1ZR0 B;  2UUY B;  3BTF I;  1ZJD B;  5JB5 A;  2HEX A;  1BTI A;  4ISN B;  1D0D B;  1IRH A;  2LFK A;  2R9P E;  3BTD I;  1P2M B;  3AUB A;  3FP6 I;  4Y0Y I;  1BF0 A;  2UUX A;  1P2Q B;  1UUB A;  3FP8 I;  1P2J I;  1P2N B;  2FI3 I;  3T62 D;  1YLC B;  4NTW B;  1F7Z I;  3AUC A;  2JOT A;  3P95 E;  1JV9 A;  5C67 C;  1LD5 A;  1TAW B;  3AUI A;  1T8L B;  1PIT A;  1BPT A;  4WXV C;  2FI4 I;  1BUN B;  2ZJX A;  1BRC I;  1DTK A;  1YC0 I;  3D65 I;  1T8N B;  4BQD A;  4DTG K;  1T8O B;  2DDJ A;  3UIR C;  2TGP I;  3FP7 J;  3TPI I;  1B0C A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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