5M5WE

Rna polymerase i open complex
Total Genus 46
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
46
sequence length
214
structure length
214
Chain Sequence
DQENERNISRLWRAFRTVKEMVKDRGYFITQEEVELPLEDFKAKYCDSMGRPQRKMMSFQANPTEESISKFPDMGSLWVEFCDEPSVGVKTMKTFVIHIQEKNFQTGIFVYQNNITPSAMKLVPSIPPATIETFNEAALVVNITHHELVPKHIRLSSDEKRELLKRYRLKESQLPRIQRADPVALYLGLKRGEVVKIIRKSETSGRYASYRICM
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Molecular Structures of Transcribing RNA Polymerase I.
pubmed doi rcsb
molecule tags Transcription
molecule keywords DNA-directed RNA polymerase I subunit RPA190
total genus 46
structure length 214
sequence length 214
ec nomenclature
pdb deposition date 2016-10-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF01191 RNA_pol_Rpb5_C RNA polymerase Rpb5, C-terminal domain
E PF03871 RNA_pol_Rpb5_N RNA polymerase Rpb5, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1340.10 Alpha Beta 3-Layer(aba) Sandwich Dna-directed Rna Polymerases I, Ii, And Iii 27 Kd Polypeptide; Chain: A; domain 1 RNA polymerase, Rpb5, N-terminal domain 5m5wE01
3.90.940.20 Alpha Beta Alpha-Beta Complex Eukaryotic RPB6 RNA polymerase subunit RPB5-like RNA polymerase subunit 5m5wE02
2NVYE 5C4XE 3S15E 3GTLE 5M5WE 3HOUE 3S16E 2PMZH 4AYBH 2E2IE 1K83E 1TWFE 3M3YE 4A3EE 2E2HE 3GTJE 4A3KE 3H3VF 1WCME 2JA7E 4BBSE 3HOWE 1I6HE 2B63E 5M3ME 3GTQE 4QIWH 4A3DE 2YU9E 3GTME 2NVTE 5IP9E 5IYCE 1TWGE 3S1RE 1TWAE 3GTKE 2E2JE 1EIKA 4BY7E 2JA5E 3S2HE 5IYDE 3PO2E 3PO3E 4BXXE 4A93E 3RZDE 3HOYE 2WB1H 3FKIE 4A3GE 3GTGE 3S2DE 4Y7NE 3HOZE 2JA8E 4C3HE 4A3JE 3S17E 1I3QE 3RZOE 1R9TE 3CQZE 5C44E 3I4NE 4A3IE 4C2ME 2Y0SH 3S1ME 4Y52E 2VUME 1I50E 5FLME 3HOXE 4BY1E 3S14E 1TWCE 5IYBE 4A3ME 3S1NE 2NVXE 1SFOE 2R93E 2JA6E 4BBRE 3M4OE 4A3CE 3GTOE 5C3EE 4A3BE 1Y1WE 2NVQE 3K7AE 1TWHE 3HKZH 4C3JE 2R92E 4C3IE 4X6AE 5C4JE 3H0GE 5M3FE 2R7ZE 1DZFA 1Y1VE 5M5YE 3GTPE 3HOVE 3S1QE 3I4ME 5IP7E 5M5XE 4A3LE 2WAQH 4A3FE 5FJ8E
chains in the Genus database with same CATH superfamily
2NVYE 5C4XE 4OINE 3S15E 1SFOF 3GTLE 2JA8F 4C3HF 4A3JF 2R93F 5M5WE 4YG2E 4KMUE 3S17F 3HOUE 1I3QF 2Y0SI 3S16E 3CQZF 4AYBK 4Q5SE 4BBRF 2BE5E 2PMZH 4AYBH 5C44F 4A3IF 3I4NF 4A3BF 2E2IE 1K83E 1TWFE 3HKZK 3K7AF 3M3YE 5TMFE 4C3JF 4C2MF 5C4JF 4A3EE 2E2HE 1Y1VF 4XLNE 4A3MF 5M5YF 3GTJE 3S1QF 4A3KE 3H3VF 3I4MF 1I50F 1WCME 2JA7E 4BBSE 4Y7NF 5D4EE 5FLMF 3HOXF 2PPBE 3HOWE 3S14F 5IYBF 1I6HE 2B63E 5IP7F 4LK0E 5E18E 3EQLE 5M3ME 3GTQE 2WAQK 4QIWH 3H3VG 4A3LF 4A3FF 4A3DE 5BYHE 1QKLA 2NVYF 5FJ8F 1ZYRE 2YU9E 3DXJE 3GTME 2NVXF 3GTLF 3S15F 2NVTE 1SMYE 5IP9E 5M5WF 2JA6F 5IYCE 1TWGE 3S1RE 4A3CF 3M4OF 4JK1E 3S16F 2PMZK 4ZH4E 5C3EF 1TWAE 3GTOF 3GTKE 1Y1WF 2NVQF 1TWHF 2A6EE 2E2JE 2R92F 4BY7E 4C3IF 4X6AF 1EIKA 2JA5E 3S2HE 3H0GF 5IYDE 5M3FF 2R7ZF 4G7ZE 4MQ9E 1YNJK 2A69E 3GTPF 3HOVF 3PO2E 4A3KF 4OIRE 4GZYE 4LJZE 3PO3E 4BXXE 4G7OE 3WODE 4BBSF 4A93E 3RZDE 4XLPE 3HOYE 2WB1H 3FKIE 4A3GE 3HOWF 3GTGE 3S2DE 4Y7NE 3HOZE 2B63F 4OIPE 5M5XF 2JA8E 4QIWK 4C3HE 4A3JE 5M3MF 3S17E 4MEYE 1I3QE 3RZOE 1R9TE 3CQZE 4YFKE 2YU9F 5C44E 3I4NE 1YNNK 5C4XF 4A3IE 2CW0E 5IP9F 4YFNE 2O5JE 5IYCF 1TWGF 1IW7E 4C2ME 3HOUF 2Y0SH 1I6VE 2A6HE 3GTKF 2E2IF 1K83F 1TWFF 3S1ME 2E2JF 3M3YF 4Y52E 2VUME 2A68E 4Q4ZE 4BY7F 4A3EF 2E2HF 1I50E 5FLME 3HOXE 3GTJF 4BY1E 4MEXE 3S14E 3PO2F 1TWCE 2KRXA 5IYBE 4XSZE 1WCMF 2JA7F 4A93F 3HOYF 4A3GF 4A3ME 3S2DF 3S1NE 3HOZF 2NVXE 1I6HF 1SFOE 2R93E 3GTQF 2JA6E 4A3DF 4BBRE 3M4OE 4A3CE 1R9TF 3RZOF 3GTOE 5C3EE 3GTMF 4A3BE 1HQME 2NVTF 1Y1WE 2NVQE 3K7AE 1TWHE 3HKZH 4KN7E 4C3JE 2R92E 4C3IE 4X6AE 5C4JE 3S1RF 3H0GE 5M3FE 2R7ZE 1TWAF 1DZFA 1Y1VE 5M5YE 4OIOE 2O5IE 3S1NF 3GTPE 4LK1E 3HOVE 3S1MF 3S1QE 4Y52F 4YFXE 2VUMF 2JA5F 3S2HF 5IYDF 4KN4E 3I4ME 5D4DE 4XSXE 5TMCE 2WB1I 4BY1F 4LLGE 1TWCF 3PO3F 4BXXF 5E17E 5IP7E 5M5XE 5D4CE 4OIQE 5IPLE 3RZDF 4A3LE 3FKIF 2WAQH 4A3FE 3GTGF 4G7HE 5FJ8E
chains in the Genus database with same CATH topology
2NVYE 5C4XE 3S15E 3GTLE 5M5WE 3HOUE 3S16E 2PMZH 4AYBH 2E2IE 1K83E 1TWFE 3M3YE 4A3EE 2E2HE 3GTJE 4A3KE 3H3VF 1WCME 2JA7E 4BBSE 3HOWE 1I6HE 2B63E 5M3ME 3GTQE 4QIWH 4A3DE 2YU9E 3GTME 2NVTE 5IP9E 5IYCE 1TWGE 3S1RE 1TWAE 3GTKE 2E2JE 1EIKA 4BY7E 2JA5E 3S2HE 5IYDE 3PO2E 3PO3E 4BXXE 4A93E 3RZDE 3HOYE 2WB1H 3FKIE 4A3GE 3GTGE 3S2DE 4Y7NE 3HOZE 2JA8E 4C3HE 4A3JE 3S17E 1I3QE 3RZOE 1R9TE 3CQZE 5C44E 3I4NE 4A3IE 4C2ME 2Y0SH 3S1ME 4Y52E 2VUME 1I50E 5FLME 3HOXE 4BY1E 3S14E 1TWCE 5IYBE 4A3ME 3S1NE 2NVXE 1SFOE 2R93E 2JA6E 4BBRE 3M4OE 4A3CE 3GTOE 5C3EE 4A3BE 1Y1WE 2NVQE 3K7AE 1TWHE 3HKZH 4C3JE 2R92E 4C3IE 4X6AE 5C4JE 3H0GE 5M3FE 2R7ZE 1DZFA 1Y1VE 5M5YE 3GTPE 3HOVE 3S1QE 3I4ME 5IP7E 5M5XE 4A3LE 2WAQH 4A3FE 5FJ8E
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2NVY E;  5C4X E;  3S15 E;  3GTL E;  5M5W E;  3HOU E;  3S16 E;  2PMZ H;  4AYB H;  2E2I E;  1K83 E;  1TWF E;  3M3Y E;  4A3E E;  2E2H E;  3GTJ E;  4A3K E;  3H3V F;  1WCM E;  2JA7 E;  4BBS E;  3HOW E;  1I6H E;  2B63 E;  5M3M E;  3GTQ E;  4QIW H;  4A3D E;  2YU9 E;  3GTM E;  2NVT E;  5IP9 E;  5IYC E;  1TWG E;  3S1R E;  1TWA E;  3GTK E;  2E2J E;  1EIK A;  4BY7 E;  2JA5 E;  3S2H E;  5IYD E;  3PO2 E;  3PO3 E;  4BXX E;  4A93 E;  3RZD E;  3HOY E;  2WB1 H;  3FKI E;  4A3G E;  3GTG E;  3S2D E;  4Y7N E;  3HOZ E;  2JA8 E;  4C3H E;  4A3J E;  3S17 E;  1I3Q E;  3RZO E;  1R9T E;  3CQZ E;  5C44 E;  3I4N E;  4A3I E;  4C2M E;  2Y0S H;  3S1M E;  4Y52 E;  2VUM E;  1I50 E;  5FLM E;  3HOX E;  4BY1 E;  3S14 E;  1TWC E;  5IYB E;  4A3M E;  3S1N E;  2NVX E;  1SFO E;  2R93 E;  2JA6 E;  4BBR E;  3M4O E;  4A3C E;  3GTO E;  5C3E E;  4A3B E;  1Y1W E;  2NVQ E;  3K7A E;  1TWH E;  3HKZ H;  4C3J E;  2R92 E;  4C3I E;  4X6A E;  5C4J E;  3H0G E;  5M3F E;  2R7Z E;  1DZF A;  1Y1V E;  5M5Y E;  3GTP E;  3HOV E;  3S1Q E;  3I4M E;  5IP7 E;  5M5X E;  4A3L E;  2WAQ H;  4A3F E;  5FJ8 E; 
#chains in the Genus database with same CATH topology
 2NVY E;  5C4X E;  4OIN E;  3S15 E;  1SFO F;  3GTL E;  2JA8 F;  4C3H F;  4A3J F;  2R93 F;  5M5W E;  4YG2 E;  4KMU E;  3S17 F;  3HOU E;  1I3Q F;  2Y0S I;  3S16 E;  3CQZ F;  4AYB K;  4Q5S E;  4BBR F;  2BE5 E;  2PMZ H;  4AYB H;  5C44 F;  4A3I F;  3I4N F;  4A3B F;  2E2I E;  1K83 E;  1TWF E;  3HKZ K;  3K7A F;  3M3Y E;  5TMF E;  4C3J F;  4C2M F;  5C4J F;  4A3E E;  2E2H E;  1Y1V F;  4XLN E;  4A3M F;  5M5Y F;  3GTJ E;  3S1Q F;  4A3K E;  3H3V F;  3I4M F;  1I50 F;  1WCM E;  2JA7 E;  4BBS E;  4Y7N F;  5D4E E;  5FLM F;  3HOX F;  2PPB E;  3HOW E;  3S14 F;  5IYB F;  1I6H E;  2B63 E;  5IP7 F;  4LK0 E;  5E18 E;  3EQL E;  5M3M E;  3GTQ E;  2WAQ K;  4QIW H;  3H3V G;  4A3L F;  4A3F F;  4A3D E;  5BYH E;  1QKL A;  2NVY F;  5FJ8 F;  1ZYR E;  2YU9 E;  3DXJ E;  3GTM E;  2NVX F;  3GTL F;  3S15 F;  2NVT E;  1SMY E;  5IP9 E;  5M5W F;  2JA6 F;  5IYC E;  1TWG E;  3S1R E;  4A3C F;  3M4O F;  4JK1 E;  3S16 F;  2PMZ K;  4ZH4 E;  5C3E F;  1TWA E;  3GTO F;  3GTK E;  1Y1W F;  2NVQ F;  1TWH F;  2A6E E;  2E2J E;  2R92 F;  4BY7 E;  4C3I F;  4X6A F;  1EIK A;  2JA5 E;  3S2H E;  3H0G F;  5IYD E;  5M3F F;  2R7Z F;  4G7Z E;  4MQ9 E;  1YNJ K;  2A69 E;  3GTP F;  3HOV F;  3PO2 E;  4A3K F;  4OIR E;  4GZY E;  4LJZ E;  3PO3 E;  4BXX E;  4G7O E;  3WOD E;  4BBS F;  4A93 E;  3RZD E;  4XLP E;  3HOY E;  2WB1 H;  3FKI E;  4A3G E;  3HOW F;  3GTG E;  3S2D E;  4Y7N E;  3HOZ E;  2B63 F;  4OIP E;  5M5X F;  2JA8 E;  4QIW K;  4C3H E;  4A3J E;  5M3M F;  3S17 E;  4MEY E;  1I3Q E;  3RZO E;  1R9T E;  3CQZ E;  4YFK E;  2YU9 F;  5C44 E;  3I4N E;  1YNN K;  5C4X F;  4A3I E;  2CW0 E;  5IP9 F;  4YFN E;  2O5J E;  5IYC F;  1TWG F;  1IW7 E;  4C2M E;  3HOU F;  2Y0S H;  1I6V E;  2A6H E;  3GTK F;  2E2I F;  1K83 F;  1TWF F;  3S1M E;  2E2J F;  3M3Y F;  4Y52 E;  2VUM E;  2A68 E;  4Q4Z E;  4BY7 F;  4A3E F;  2E2H F;  1I50 E;  5FLM E;  3HOX E;  3GTJ F;  4BY1 E;  4MEX E;  3S14 E;  3PO2 F;  1TWC E;  2KRX A;  5IYB E;  4XSZ E;  1WCM F;  2JA7 F;  4A93 F;  3HOY F;  4A3G F;  4A3M E;  3S2D F;  3S1N E;  3HOZ F;  2NVX E;  1I6H F;  1SFO E;  2R93 E;  3GTQ F;  2JA6 E;  4A3D F;  4BBR E;  3M4O E;  4A3C E;  1R9T F;  3RZO F;  3GTO E;  5C3E E;  3GTM F;  4A3B E;  1HQM E;  2NVT F;  1Y1W E;  2NVQ E;  3K7A E;  1TWH E;  3HKZ H;  4KN7 E;  4C3J E;  2R92 E;  4C3I E;  4X6A E;  5C4J E;  3S1R F;  3H0G E;  5M3F E;  2R7Z E;  1TWA F;  1DZF A;  1Y1V E;  5M5Y E;  4OIO E;  2O5I E;  3S1N F;  3GTP E;  4LK1 E;  3HOV E;  3S1M F;  3S1Q E;  4Y52 F;  4YFX E;  2VUM F;  2JA5 F;  3S2H F;  5IYD F;  4KN4 E;  3I4M E;  5D4D E;  4XSX E;  5TMC E;  2WB1 I;  4BY1 F;  4LLG E;  1TWC F;  3PO3 F;  4BXX F;  5E17 E;  5IP7 E;  5M5X E;  5D4C E;  4OIQ E;  5IPL E;  3RZD F;  4A3L E;  3FKI F;  2WAQ H;  4A3F E;  3GTG F;  4G7H E;  5FJ8 E; 
#chains in the Genus database with same CATH homology
 2NVY E;  5C4X E;  3S15 E;  3GTL E;  5M5W E;  3HOU E;  3S16 E;  2PMZ H;  4AYB H;  2E2I E;  1K83 E;  1TWF E;  3M3Y E;  4A3E E;  2E2H E;  3GTJ E;  4A3K E;  3H3V F;  1WCM E;  2JA7 E;  4BBS E;  3HOW E;  1I6H E;  2B63 E;  5M3M E;  3GTQ E;  4QIW H;  4A3D E;  2YU9 E;  3GTM E;  2NVT E;  5IP9 E;  5IYC E;  1TWG E;  3S1R E;  1TWA E;  3GTK E;  2E2J E;  1EIK A;  4BY7 E;  2JA5 E;  3S2H E;  5IYD E;  3PO2 E;  3PO3 E;  4BXX E;  4A93 E;  3RZD E;  3HOY E;  2WB1 H;  3FKI E;  4A3G E;  3GTG E;  3S2D E;  4Y7N E;  3HOZ E;  2JA8 E;  4C3H E;  4A3J E;  3S17 E;  1I3Q E;  3RZO E;  1R9T E;  3CQZ E;  5C44 E;  3I4N E;  4A3I E;  4C2M E;  2Y0S H;  3S1M E;  4Y52 E;  2VUM E;  1I50 E;  5FLM E;  3HOX E;  4BY1 E;  3S14 E;  1TWC E;  5IYB E;  4A3M E;  3S1N E;  2NVX E;  1SFO E;  2R93 E;  2JA6 E;  4BBR E;  3M4O E;  4A3C E;  3GTO E;  5C3E E;  4A3B E;  1Y1W E;  2NVQ E;  3K7A E;  1TWH E;  3HKZ H;  4C3J E;  2R92 E;  4C3I E;  4X6A E;  5C4J E;  3H0G E;  5M3F E;  2R7Z E;  1DZF A;  1Y1V E;  5M5Y E;  3GTP E;  3HOV E;  3S1Q E;  3I4M E;  5IP7 E;  5M5X E;  4A3L E;  2WAQ H;  4A3F E;  5FJ8 E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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