5M5WF

Rna polymerase i open complex
Total Genus 25
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
25
sequence length
100
structure length
100
Chain Sequence
PEDFQQHEQIRRKTLKEKAIPKDQRATTPYMTKYERARILGTRALQISMNAPVFVDLEGETDPLRIAMKELAEKKIPLVIRRYLPDGSFEDWSVEELIVD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Molecular Structures of Transcribing RNA Polymerase I.
pubmed doi rcsb
molecule tags Transcription
molecule keywords DNA-directed RNA polymerase I subunit RPA190
total genus 25
structure length 100
sequence length 100
ec nomenclature
pdb deposition date 2016-10-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
F PF01192 RNA_pol_Rpb6 RNA polymerase Rpb6
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.940.10 Alpha Beta Alpha-Beta Complex Eukaryotic RPB6 RNA polymerase subunit Eukaryotic RPB6 RNA polymerase subunit 5m5wF00
3I4MF 4A3DF 4YG2E 1R9TF 3S2HF 4KMUE 4ZH4E 5IYCF 4A3FF 4BBSF 1TWAF 1YNJK 5FJ8F 3PO3F 3S1NF 4A93F 1TWGF 4MQ9E 4A3MF 3HOVF 4G7OE 5IP7F 1TWCF 2JA6F 1I6VE 2O5JE 3HOUF 4C3HF 4A3BF 1IW7E 5C3EF 5C4JF 5IPLE 2YU9F 2NVYF 5M5XF 4MEXE 3CQZF 4OIRE 1TWHF 3HOZF 3GTGF 1YNNK 4Y52F 5FLMF 3GTOF 3I4NF 3HOXF 3PO2F 4JK1E 4X6AF 5M3MF 4A3JF 4GZYE 4A3EF 3RZOF 4AYBK 3GTJF 2PMZK 5IYDF 3S14F 5TMCE 3GTMF 3GTPF 3HOWF 2R92F 5D4EE 2E2HF 4C2MF 2JA8F 4YFNE 4KN7E 2PPBE 4A3IF 2JA7F 5C44F 2R7ZF 4A3KF 1SMYE 2BE5E 2CW0E 4LJZE 5TMFE 5E18E 2E2JF 3GTQF 1K83F 3WODE 2Y0SI 4YFXE 3S2DF 3S1MF 5D4CE 3HKZK 1Y1VF 4LK1E 2A69E 4C3IF 1QKLA 5M5YF 4YFKE 4A3LF 3S17F 4XSZE 1I3QF 3S16F 4Y7NF 3GTKF 2A68E 2WB1I 1ZYRE 2E2IF 3RZDF 3S1QF 4G7HE 3S15F 5M5WF 3DXJE 4MEYE 2NVXF 1WCMF 4XSXE 4Q5SE 3H3VG 2O5IE 4LLGE 2A6HE 2A6EE 4BBRF 5IYBF 4OINE 4OIQE 3FKIF 4KN4E 4BY1F 2VUMF 2JA5F 1TWFF 5BYHE 2R93F 4G7ZE 4BY7F 4C3JF 3GTLF 5M3FF 4OIPE 5D4DE 1I6HF 4LK0E 4BXXF 4OIOE 3S1RF 3M3YF 3H0GF 4A3GF 5E17E 3M4OF 1HQME 4A3CF 1SFOF 2NVTF 4XLNE 1Y1WF 2WAQK 5C4XF 5IP9F 2NVQF 3EQLE 4XLPE 2B63F 4Q4ZE 1I50F 3K7AF 3HOYF
chains in the Genus database with same CATH superfamily
3I4MF 4A93E 4BXXE 4A3DF 1EIKA 4A3ME 4YG2E 1R9TF 5IP7E 3S1RE 1TWCE 3M3YE 3H0GE 3S2HF 4KMUE 4ZH4E 5IYCF 4A3FF 4C3HE 4BBSF 1TWAF 2Y0SH 1YNJK 5FJ8F 5C3EE 5C4JE 3PO3F 3S1NF 4A93F 4A3GE 3M4OE 4A3CE 1TWGF 4MQ9E 4A3MF 1SFOE 2YU9E 3HOVF 4G7OE 5IP7F 1TWCF 1Y1WE 3HOZE 2JA6F 5C4XE 5FLME 1I6VE 5IP9E 3HOUF 3GTOE 2O5JE 4C3HF 4A3BF 1IW7E 5C3EF 5C4JF 2WB1H 2B63E 5IPLE 1I50E 3K7AE 2YU9F 2NVYF 5M5XF 4MEXE 3CQZF 3GTJE 4OIRE 3HOYE 1TWHF 3RZOE 3HOZF 3I4ME 5IYDE 1R9TE 1YNNK 4Y52F 5FLMF 3GTGF 3GTOF 3I4NF 3S14E 3HOXF 3PO2F 4JK1E 4C2ME 3S2HE 5M3MF 4X6AF 5IYCE 4A3FE 4A3JF 4BBSE 4GZYE 1TWAE 1I6HE 5FJ8E 4A3EF 3PO3E 4AYBK 2JA8E 3GTJF 3RZOF 3S1NE 2PMZK 1TWGE 3HOVE 5IYDF 3S14F 4A3IE 5TMCE 3GTMF 3GTPF 3HOWF 2JA7E 2R92F 5D4EE 2R7ZE 2E2HF 4C2MF 2JA6E 3HOUE 4QIWK 4A3BE 2JA8F 4YFNE 4KN7E 2PPBE 2NVYE 1K83E 5M5XE 3CQZE 4A3IF 1TWHE 2JA7F 5C44F 3GTGE 2R7ZF 4Y52E 3I4NE 3S2DE 3HOXE 4A3KF 3PO2E 4X6AE 1SMYE 2BE5E 2CW0E 4LJZE 5M3ME 5TMFE 5E18E 4C3IE 4A3JE 2E2JF 3GTQF 2WAQH 4A3EE 1K83F 3WODE 1I3QE 4Y7NE 2Y0SI 3GTME 4YFXE 3GTPE 3HOWE 3S1MF 2E2IE 5D4CE 3S2DF 2E2HE 2R92E 3HKZK 1Y1VF 4LK1E 3RZDE 3S1QE 2A69E 2PMZH 4C3IF 1QKLA 5M5YF 4YFKE 3S15E 3S17F 4A3LF 4XSZE 1I3QF 3S16F 4Y7NF 2NVXE 2A68E 3GTKF 2WB1I 1ZYRE 4QIWH 5C44E 2E2IF 3RZDF 3S1QF 4G7HE 4A3KE 3S15F 5M5WF 3DXJE 5IYBE 4MEYE 2E2JE 3GTQE 2NVXF 1WCMF 4XSXE 4Q5SE 4A3DE 3H3VG 2O5IE 2JA5E 4LLGE 1TWFE 3S1ME 2A6HE 1Y1VE 2A6EE 4BBRF 5IYBF 4OINE 4OIQE 3H3VF 4C3JE 3FKIF 4KN4E 5M5YE 3S17E 4A3LE 4BY1F 2VUMF 3S16E 3GTKE 2JA5F 1TWFF 1DZFA 5BYHE 2R93F 4G7ZE 4BY7F 4AYBH 4C3JF 5M5WE 3GTLF 5M3FF 4OIPE 5D4DE 1I6HF 1WCME 4LK0E 4BXXF 2KRXA 2NVTE 4OIOE 3S1RF 3M3YF 3H0GF 2NVQE 4BBRE 3FKIE 4A3GF 5E17E 4BY1E 1HQME 2VUME 3M4OF 4A3CF 1SFOF 2NVTF 4XLNE 2R93E 1Y1WF 2WAQK 4BY7E 5C4XF 5IP9F 2NVQF 3GTLE 3EQLE 4XLPE 2B63F 4Q4ZE 5M3FE 1I50F 3K7AF 3HOYF 3HKZH
chains in the Genus database with same CATH topology
3I4MF 4A3DF 4YG2E 1R9TF 3S2HF 4KMUE 4ZH4E 5IYCF 4A3FF 4BBSF 1TWAF 1YNJK 5FJ8F 3PO3F 3S1NF 4A93F 1TWGF 4MQ9E 4A3MF 3HOVF 4G7OE 5IP7F 1TWCF 2JA6F 1I6VE 2O5JE 3HOUF 4C3HF 4A3BF 1IW7E 5C3EF 5C4JF 5IPLE 2YU9F 2NVYF 5M5XF 4MEXE 3CQZF 4OIRE 1TWHF 3HOZF 3GTGF 1YNNK 4Y52F 5FLMF 3GTOF 3I4NF 3HOXF 3PO2F 4JK1E 4X6AF 5M3MF 4A3JF 4GZYE 4A3EF 3RZOF 4AYBK 3GTJF 2PMZK 5IYDF 3S14F 5TMCE 3GTMF 3GTPF 3HOWF 2R92F 5D4EE 2E2HF 4C2MF 4QIWK 2JA8F 4YFNE 4KN7E 2PPBE 4A3IF 2JA7F 5C44F 2R7ZF 4A3KF 1SMYE 2BE5E 2CW0E 4LJZE 5TMFE 5E18E 2E2JF 3GTQF 1K83F 3WODE 2Y0SI 4YFXE 3S2DF 3S1MF 5D4CE 3HKZK 1Y1VF 4LK1E 2A69E 4C3IF 1QKLA 5M5YF 4YFKE 4A3LF 3S17F 4XSZE 1I3QF 3S16F 4Y7NF 3GTKF 2A68E 2WB1I 1ZYRE 2E2IF 3RZDF 3S1QF 4G7HE 3S15F 5M5WF 3DXJE 4MEYE 2NVXF 1WCMF 4XSXE 4Q5SE 3H3VG 2O5IE 4LLGE 2A6HE 2A6EE 4BBRF 5IYBF 4OINE 4OIQE 3FKIF 4KN4E 4BY1F 2VUMF 2JA5F 1TWFF 5BYHE 2R93F 4G7ZE 4BY7F 4C3JF 3GTLF 5M3FF 4OIPE 5D4DE 1I6HF 4LK0E 4BXXF 2KRXA 4OIOE 3S1RF 3M3YF 3H0GF 4A3GF 5E17E 3M4OF 1HQME 4A3CF 1SFOF 2NVTF 4XLNE 1Y1WF 2WAQK 5C4XF 5IP9F 2NVQF 3EQLE 4XLPE 2B63F 4Q4ZE 1I50F 3K7AF 3HOYF
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3I4M F;  4A3D F;  4YG2 E;  1R9T F;  3S2H F;  4KMU E;  4ZH4 E;  5IYC F;  4A3F F;  4BBS F;  1TWA F;  1YNJ K;  5FJ8 F;  3PO3 F;  3S1N F;  4A93 F;  1TWG F;  4MQ9 E;  4A3M F;  3HOV F;  4G7O E;  5IP7 F;  1TWC F;  2JA6 F;  1I6V E;  2O5J E;  3HOU F;  4C3H F;  4A3B F;  1IW7 E;  5C3E F;  5C4J F;  5IPL E;  2YU9 F;  2NVY F;  5M5X F;  4MEX E;  3CQZ F;  4OIR E;  1TWH F;  3HOZ F;  3GTG F;  1YNN K;  4Y52 F;  5FLM F;  3GTO F;  3I4N F;  3HOX F;  3PO2 F;  4JK1 E;  4X6A F;  5M3M F;  4A3J F;  4GZY E;  4A3E F;  3RZO F;  4AYB K;  3GTJ F;  2PMZ K;  5IYD F;  3S14 F;  5TMC E;  3GTM F;  3GTP F;  3HOW F;  2R92 F;  5D4E E;  2E2H F;  4C2M F;  2JA8 F;  4YFN E;  4KN7 E;  2PPB E;  4A3I F;  2JA7 F;  5C44 F;  2R7Z F;  4A3K F;  1SMY E;  2BE5 E;  2CW0 E;  4LJZ E;  5TMF E;  5E18 E;  2E2J F;  3GTQ F;  1K83 F;  3WOD E;  2Y0S I;  4YFX E;  3S2D F;  3S1M F;  5D4C E;  3HKZ K;  1Y1V F;  4LK1 E;  2A69 E;  4C3I F;  1QKL A;  5M5Y F;  4YFK E;  4A3L F;  3S17 F;  4XSZ E;  1I3Q F;  3S16 F;  4Y7N F;  3GTK F;  2A68 E;  2WB1 I;  1ZYR E;  2E2I F;  3RZD F;  3S1Q F;  4G7H E;  3S15 F;  5M5W F;  3DXJ E;  4MEY E;  2NVX F;  1WCM F;  4XSX E;  4Q5S E;  3H3V G;  2O5I E;  4LLG E;  2A6H E;  2A6E E;  4BBR F;  5IYB F;  4OIN E;  4OIQ E;  3FKI F;  4KN4 E;  4BY1 F;  2VUM F;  2JA5 F;  1TWF F;  5BYH E;  2R93 F;  4G7Z E;  4BY7 F;  4C3J F;  3GTL F;  5M3F F;  4OIP E;  5D4D E;  1I6H F;  4LK0 E;  4BXX F;  4OIO E;  3S1R F;  3M3Y F;  3H0G F;  4A3G F;  5E17 E;  3M4O F;  1HQM E;  4A3C F;  1SFO F;  2NVT F;  4XLN E;  1Y1W F;  2WAQ K;  5C4X F;  5IP9 F;  2NVQ F;  3EQL E;  4XLP E;  2B63 F;  4Q4Z E;  1I50 F;  3K7A F;  3HOY F; 
#chains in the Genus database with same CATH topology
 3I4M F;  4A93 E;  4BXX E;  4A3D F;  1EIK A;  4A3M E;  4YG2 E;  1R9T F;  5IP7 E;  3S1R E;  1TWC E;  3M3Y E;  3H0G E;  3S2H F;  4KMU E;  4ZH4 E;  5IYC F;  4A3F F;  4C3H E;  4BBS F;  1TWA F;  2Y0S H;  1YNJ K;  5FJ8 F;  5C3E E;  5C4J E;  3PO3 F;  3S1N F;  4A93 F;  4A3G E;  3M4O E;  4A3C E;  1TWG F;  4MQ9 E;  4A3M F;  1SFO E;  2YU9 E;  3HOV F;  4G7O E;  5IP7 F;  1TWC F;  1Y1W E;  3HOZ E;  2JA6 F;  5C4X E;  5FLM E;  1I6V E;  5IP9 E;  3HOU F;  3GTO E;  2O5J E;  4C3H F;  4A3B F;  1IW7 E;  5C3E F;  5C4J F;  2WB1 H;  2B63 E;  5IPL E;  1I50 E;  3K7A E;  2YU9 F;  2NVY F;  5M5X F;  4MEX E;  3CQZ F;  3GTJ E;  4OIR E;  3HOY E;  1TWH F;  3RZO E;  3HOZ F;  3I4M E;  5IYD E;  1R9T E;  1YNN K;  4Y52 F;  5FLM F;  3GTG F;  3GTO F;  3I4N F;  3S14 E;  3HOX F;  3PO2 F;  4JK1 E;  4C2M E;  3S2H E;  5M3M F;  4X6A F;  5IYC E;  4A3F E;  4A3J F;  4BBS E;  4GZY E;  1TWA E;  1I6H E;  5FJ8 E;  4A3E F;  3PO3 E;  4AYB K;  2JA8 E;  3GTJ F;  3RZO F;  3S1N E;  2PMZ K;  1TWG E;  3HOV E;  5IYD F;  3S14 F;  4A3I E;  5TMC E;  3GTM F;  3GTP F;  3HOW F;  2JA7 E;  2R92 F;  5D4E E;  2R7Z E;  2E2H F;  4C2M F;  2JA6 E;  3HOU E;  4QIW K;  4A3B E;  2JA8 F;  4YFN E;  4KN7 E;  2PPB E;  2NVY E;  1K83 E;  5M5X E;  3CQZ E;  4A3I F;  1TWH E;  2JA7 F;  5C44 F;  3GTG E;  2R7Z F;  4Y52 E;  3I4N E;  3S2D E;  3HOX E;  4A3K F;  3PO2 E;  4X6A E;  1SMY E;  2BE5 E;  2CW0 E;  4LJZ E;  5M3M E;  5TMF E;  5E18 E;  4C3I E;  4A3J E;  2E2J F;  3GTQ F;  2WAQ H;  4A3E E;  1K83 F;  3WOD E;  1I3Q E;  4Y7N E;  2Y0S I;  3GTM E;  4YFX E;  3GTP E;  3HOW E;  3S1M F;  2E2I E;  5D4C E;  3S2D F;  2E2H E;  2R92 E;  3HKZ K;  1Y1V F;  4LK1 E;  3RZD E;  3S1Q E;  2A69 E;  2PMZ H;  4C3I F;  1QKL A;  5M5Y F;  4YFK E;  3S15 E;  3S17 F;  4A3L F;  4XSZ E;  1I3Q F;  3S16 F;  4Y7N F;  2NVX E;  2A68 E;  3GTK F;  2WB1 I;  1ZYR E;  4QIW H;  5C44 E;  2E2I F;  3RZD F;  3S1Q F;  4G7H E;  4A3K E;  3S15 F;  5M5W F;  3DXJ E;  5IYB E;  4MEY E;  2E2J E;  3GTQ E;  2NVX F;  1WCM F;  4XSX E;  4Q5S E;  4A3D E;  3H3V G;  2O5I E;  2JA5 E;  4LLG E;  1TWF E;  3S1M E;  2A6H E;  1Y1V E;  2A6E E;  4BBR F;  5IYB F;  4OIN E;  4OIQ E;  3H3V F;  4C3J E;  3FKI F;  4KN4 E;  5M5Y E;  3S17 E;  4A3L E;  4BY1 F;  2VUM F;  3S16 E;  3GTK E;  2JA5 F;  1TWF F;  1DZF A;  5BYH E;  2R93 F;  4G7Z E;  4BY7 F;  4AYB H;  4C3J F;  5M5W E;  3GTL F;  5M3F F;  4OIP E;  5D4D E;  1I6H F;  1WCM E;  4LK0 E;  4BXX F;  2KRX A;  2NVT E;  4OIO E;  3S1R F;  3M3Y F;  3H0G F;  2NVQ E;  4BBR E;  3FKI E;  4A3G F;  5E17 E;  4BY1 E;  1HQM E;  2VUM E;  3M4O F;  4A3C F;  1SFO F;  2NVT F;  4XLN E;  2R93 E;  1Y1W F;  2WAQ K;  4BY7 E;  5C4X F;  5IP9 F;  2NVQ F;  3GTL E;  3EQL E;  4XLP E;  2B63 F;  4Q4Z E;  5M3F E;  1I50 F;  3K7A F;  3HOY F;  3HKZ H; 
#chains in the Genus database with same CATH homology
 3I4M F;  4A3D F;  4YG2 E;  1R9T F;  3S2H F;  4KMU E;  4ZH4 E;  5IYC F;  4A3F F;  4BBS F;  1TWA F;  1YNJ K;  5FJ8 F;  3PO3 F;  3S1N F;  4A93 F;  1TWG F;  4MQ9 E;  4A3M F;  3HOV F;  4G7O E;  5IP7 F;  1TWC F;  2JA6 F;  1I6V E;  2O5J E;  3HOU F;  4C3H F;  4A3B F;  1IW7 E;  5C3E F;  5C4J F;  5IPL E;  2YU9 F;  2NVY F;  5M5X F;  4MEX E;  3CQZ F;  4OIR E;  1TWH F;  3HOZ F;  3GTG F;  1YNN K;  4Y52 F;  5FLM F;  3GTO F;  3I4N F;  3HOX F;  3PO2 F;  4JK1 E;  4X6A F;  5M3M F;  4A3J F;  4GZY E;  4A3E F;  3RZO F;  4AYB K;  3GTJ F;  2PMZ K;  5IYD F;  3S14 F;  5TMC E;  3GTM F;  3GTP F;  3HOW F;  2R92 F;  5D4E E;  2E2H F;  4C2M F;  4QIW K;  2JA8 F;  4YFN E;  4KN7 E;  2PPB E;  4A3I F;  2JA7 F;  5C44 F;  2R7Z F;  4A3K F;  1SMY E;  2BE5 E;  2CW0 E;  4LJZ E;  5TMF E;  5E18 E;  2E2J F;  3GTQ F;  1K83 F;  3WOD E;  2Y0S I;  4YFX E;  3S2D F;  3S1M F;  5D4C E;  3HKZ K;  1Y1V F;  4LK1 E;  2A69 E;  4C3I F;  1QKL A;  5M5Y F;  4YFK E;  4A3L F;  3S17 F;  4XSZ E;  1I3Q F;  3S16 F;  4Y7N F;  3GTK F;  2A68 E;  2WB1 I;  1ZYR E;  2E2I F;  3RZD F;  3S1Q F;  4G7H E;  3S15 F;  5M5W F;  3DXJ E;  4MEY E;  2NVX F;  1WCM F;  4XSX E;  4Q5S E;  3H3V G;  2O5I E;  4LLG E;  2A6H E;  2A6E E;  4BBR F;  5IYB F;  4OIN E;  4OIQ E;  3FKI F;  4KN4 E;  4BY1 F;  2VUM F;  2JA5 F;  1TWF F;  5BYH E;  2R93 F;  4G7Z E;  4BY7 F;  4C3J F;  3GTL F;  5M3F F;  4OIP E;  5D4D E;  1I6H F;  4LK0 E;  4BXX F;  2KRX A;  4OIO E;  3S1R F;  3M3Y F;  3H0G F;  4A3G F;  5E17 E;  3M4O F;  1HQM E;  4A3C F;  1SFO F;  2NVT F;  4XLN E;  1Y1W F;  2WAQ K;  5C4X F;  5IP9 F;  2NVQ F;  3EQL E;  4XLP E;  2B63 F;  4Q4Z E;  1I50 F;  3K7A F;  3HOY F; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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