5ADQB

Crystal structure of human tankyrase 2 in complex with jw55
Total Genus 1
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
1
sequence length
46
structure length
46
Chain Sequence
AHSPPGHHSVTGRPSVNGLALAEYVIYRGEQAYPEYLITYQIMRPE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Development and Structural Analysis of Adenosine Site Binding Tankyrase Inhibitors.
pubmed doi rcsb
molecule keywords TANKYRASE-2
molecule tags Transferase
source organism Homo sapiens
total genus 1
structure length 46
sequence length 46
ec nomenclature ec 2.4.2.30: NAD(+) ADP-ribosyltransferase.
pdb deposition date 2015-08-24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1620.50 Alpha Beta 3-Layer(aba) Sandwich YefM-like fold YefM-like fold 5adqB00
4HKKB 4HKNC 4HLFC 4L33C 4UI4C 4HL5C 4L2KC 4UI6C 4HLGC 4L31C 4L0IC 4L0SC 5ADTB 5C5QC 4UI3C 4L2GC 5C5PC 4L32C 4UI8C 4KZLC 4L0VC 4HLKC 4L2FC 4UVPB 4L0BC 4L10C 4L09C 5ADSB 4HKIC 4KZUC 5ADRB 4L0TC 5FPFC 4HMHC 4HLMC 4KZQC 5C5RC 5ADQB 4L34C 4HLHC 4UI7C 4UI5C
chains in the Genus database with same CATH superfamily
4ZM0A 4HKKB 4HKNC 4HLFC 4L33C 4UI4C 2ODKA 3KH2E 3HRYA 3OEIE 4HL5C 4L2KC 4UI6C 4HLGC 2A6QA 4L31C 4L0IC 4L0SC 5ADTB 4ZLXA 5C5QC 4UI3C 4L2GC 5C5PC 4L32C 4UI8C 3G5OA 4KZLC 4L0VC 4HLKC 4L2FC 3HJ6A 4UVPB 4L0BC 4L10C 3OEIA 4L09C 5ADSB 4HKIC 4KZUC 5ADRB 4L0TC 3CTOA 3K6QA 5FPFC 4HMHC 4HLMC 4KZQC 5C5RC 5ADQB 4L34C 3D55A 4ZM2A 3HS2A 2ZIXB 4HLHC 3K33B 4UI7C 4UI5C
chains in the Genus database with same CATH topology
4HKKB 4HKNC 4HLFC 4L33C 4UI4C 4HL5C 4L2KC 4UI6C 4HLGC 4L31C 4L0IC 4L0SC 5ADTB 5C5QC 4UI3C 4L2GC 5C5PC 4L32C 4UI8C 4KZLC 4L0VC 4HLKC 4L2FC 3HJ6A 4UVPB 4L0BC 4L10C 4L09C 5ADSB 4HKIC 4KZUC 5ADRB 4L0TC 5FPFC 4HMHC 4HLMC 4KZQC 5C5RC 5ADQB 4L34C 2ZIXB 4HLHC 4UI7C 4UI5C
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4HKK B;  4HKN C;  4HLF C;  4L33 C;  4UI4 C;  4HL5 C;  4L2K C;  4UI6 C;  4HLG C;  4L31 C;  4L0I C;  4L0S C;  5ADT B;  5C5Q C;  4UI3 C;  4L2G C;  5C5P C;  4L32 C;  4UI8 C;  4KZL C;  4L0V C;  4HLK C;  4L2F C;  4UVP B;  4L0B C;  4L10 C;  4L09 C;  5ADS B;  4HKI C;  4KZU C;  5ADR B;  4L0T C;  5FPF C;  4HMH C;  4HLM C;  4KZQ C;  5C5R C;  5ADQ B;  4L34 C;  4HLH C;  4UI7 C;  4UI5 C; 
#chains in the Genus database with same CATH topology
 4ZM0 A;  4HKK B;  4HKN C;  4HLF C;  4L33 C;  4UI4 C;  2ODK A;  3KH2 E;  3HRY A;  3OEI E;  4HL5 C;  4L2K C;  4UI6 C;  4HLG C;  2A6Q A;  4L31 C;  4L0I C;  4L0S C;  5ADT B;  4ZLX A;  5C5Q C;  4UI3 C;  4L2G C;  5C5P C;  4L32 C;  4UI8 C;  3G5O A;  4KZL C;  4L0V C;  4HLK C;  4L2F C;  3HJ6 A;  4UVP B;  4L0B C;  4L10 C;  3OEI A;  4L09 C;  5ADS B;  4HKI C;  4KZU C;  5ADR B;  4L0T C;  3CTO A;  3K6Q A;  5FPF C;  4HMH C;  4HLM C;  4KZQ C;  5C5R C;  5ADQ B;  4L34 C;  3D55 A;  4ZM2 A;  3HS2 A;  2ZIX B;  4HLH C;  3K33 B;  4UI7 C;  4UI5 C; 
#chains in the Genus database with same CATH homology
 4HKK B;  4HKN C;  4HLF C;  4L33 C;  4UI4 C;  4HL5 C;  4L2K C;  4UI6 C;  4HLG C;  4L31 C;  4L0I C;  4L0S C;  5ADT B;  5C5Q C;  4UI3 C;  4L2G C;  5C5P C;  4L32 C;  4UI8 C;  4KZL C;  4L0V C;  4HLK C;  4L2F C;  3HJ6 A;  4UVP B;  4L0B C;  4L10 C;  4L09 C;  5ADS B;  4HKI C;  4KZU C;  5ADR B;  4L0T C;  5FPF C;  4HMH C;  4HLM C;  4KZQ C;  5C5R C;  5ADQ B;  4L34 C;  2ZIX B;  4HLH C;  4UI7 C;  4UI5 C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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