5ADQB

Crystal structure of human tankyrase 2 in complex with jw55
Total Genus 1
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
1
sequence length
46
structure length
46
Chain Sequence
AHSPPGHHSVTGRPSVNGLALAEYVIYRGEQAYPEYLITYQIMRPE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Development and Structural Analysis of Adenosine Site Binding Tankyrase Inhibitors.
pubmed doi rcsb
molecule tags Transferase
source organism Homo sapiens
molecule keywords TANKYRASE-2
total genus 1
structure length 46
sequence length 46
ec nomenclature ec 2.4.2.30: NAD(+) ADP-ribosyltransferase.
pdb deposition date 2015-08-24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1620.50 Alpha Beta 3-Layer(aba) Sandwich YefM-like fold YefM-like fold 5adqB00
5ADSB 4L0SC 4UVPB 4HLMC 4HLGC 4L2FC 5C5QC 4L10C 4KZUC 5ADTB 4L0VC 5C5PC 4L0TC 4UI7C 4UI5C 4HMHC 4UI8C 4HL5C 4KZQC 4L33C 5ADRB 5C5RC 4HKIC 4HLFC 4HKNC 5ADQB 4UI4C 4UI3C 4L34C 4L32C 4L2GC 4HLHC 4UI6C 4L0BC 4HKKB 4KZLC 4L0IC 5FPFC 4L2KC 4L09C 4HLKC 4L31C
chains in the Genus database with same CATH superfamily
3OEIE 5ADSB 4L0SC 2ODKA 3CTOA 4UVPB 4HLMC 4HLGC 4L2FC 3K33B 4L10C 5C5QC 4KZUC 2ZIXB 5ADTB 4L0VC 5C5PC 4HLKC 4L0TC 4UI7C 3KH2E 4UI5C 4HMHC 3D55A 4UI8C 4HL5C 4KZQC 3HRYA 4L33C 5ADRB 5C5RC 3HJ6A 4HKIC 4HLFC 4HKNC 4ZLXA 3OEIA 4UI4C 4UI3C 5ADQB 4L34C 2A6QA 4L32C 4L2GC 4ZM0A 4HLHC 4UI6C 4L0BC 4HKKB 4KZLC 3HS2A 4L0IC 5FPFC 4L2KC 4ZM2A 4L09C 3K6QA 3G5OA 4L31C
chains in the Genus database with same CATH topology
5ADSB 4L0SC 4UVPB 4HLMC 4HLGC 4L2FC 5C5QC 4L10C 4KZUC 2ZIXB 5ADTB 4L0VC 5C5PC 4L0TC 4UI7C 4UI5C 4HMHC 4UI8C 4HL5C 4KZQC 4L33C 5ADRB 5C5RC 4HKIC 3HJ6A 4HLFC 4HKNC 5ADQB 4UI4C 4UI3C 4L34C 4L32C 4L2GC 4HLHC 4UI6C 4L0BC 4HKKB 4KZLC 4L0IC 5FPFC 4L2KC 4L09C 4HLKC 4L31C
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5ADS B;  4L0S C;  4UVP B;  4HLM C;  4HLG C;  4L2F C;  5C5Q C;  4L10 C;  4KZU C;  5ADT B;  4L0V C;  5C5P C;  4L0T C;  4UI7 C;  4UI5 C;  4HMH C;  4UI8 C;  4HL5 C;  4KZQ C;  4L33 C;  5ADR B;  5C5R C;  4HKI C;  4HLF C;  4HKN C;  5ADQ B;  4UI4 C;  4UI3 C;  4L34 C;  4L32 C;  4L2G C;  4HLH C;  4UI6 C;  4L0B C;  4HKK B;  4KZL C;  4L0I C;  5FPF C;  4L2K C;  4L09 C;  4HLK C;  4L31 C; 
#chains in the Genus database with same CATH topology
 3OEI E;  5ADS B;  4L0S C;  2ODK A;  3CTO A;  4UVP B;  4HLM C;  4HLG C;  4L2F C;  3K33 B;  4L10 C;  5C5Q C;  4KZU C;  2ZIX B;  5ADT B;  4L0V C;  5C5P C;  4HLK C;  4L0T C;  4UI7 C;  3KH2 E;  4UI5 C;  4HMH C;  3D55 A;  4UI8 C;  4HL5 C;  4KZQ C;  3HRY A;  4L33 C;  5ADR B;  5C5R C;  3HJ6 A;  4HKI C;  4HLF C;  4HKN C;  4ZLX A;  3OEI A;  4UI4 C;  4UI3 C;  5ADQ B;  4L34 C;  2A6Q A;  4L32 C;  4L2G C;  4ZM0 A;  4HLH C;  4UI6 C;  4L0B C;  4HKK B;  4KZL C;  3HS2 A;  4L0I C;  5FPF C;  4L2K C;  4ZM2 A;  4L09 C;  3K6Q A;  3G5O A;  4L31 C; 
#chains in the Genus database with same CATH homology
 5ADS B;  4L0S C;  4UVP B;  4HLM C;  4HLG C;  4L2F C;  5C5Q C;  4L10 C;  4KZU C;  2ZIX B;  5ADT B;  4L0V C;  5C5P C;  4L0T C;  4UI7 C;  4UI5 C;  4HMH C;  4UI8 C;  4HL5 C;  4KZQ C;  4L33 C;  5ADR B;  5C5R C;  4HKI C;  3HJ6 A;  4HLF C;  4HKN C;  5ADQ B;  4UI4 C;  4UI3 C;  4L34 C;  4L32 C;  4L2G C;  4HLH C;  4UI6 C;  4L0B C;  4HKK B;  4KZL C;  4L0I C;  5FPF C;  4L2K C;  4L09 C;  4HLK C;  4L31 C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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