5ADSB

Crystal structure of human tankyrase 2 in complex with od39
Total Genus 1
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
1
sequence length
46
structure length
46
Chain Sequence
AHSPPGHHSVTGRPSVNGLALAEYVIYRGEQAYPEYLITYQIMRPE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Development and Structural Analysis of Adenosine Site Binding Tankyrase Inhibitors.
pubmed doi rcsb
molecule tags Transferase
source organism Homo sapiens
molecule keywords TANKYRASE-2
total genus 1
structure length 46
sequence length 46
ec nomenclature ec 2.4.2.30: NAD(+) ADP-ribosyltransferase.
pdb deposition date 2015-08-24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1620.50 Alpha Beta 3-Layer(aba) Sandwich YefM-like fold YefM-like fold 5adsB00
4L32C 5FPFC 4L2KC 4L0VC 4L10C 4UI3C 5C5QC 4HKKB 4HLMC 4HKIC 4HLFC 4KZLC 4HLHC 4UI8C 4UI6C 4HMHC 4KZUC 4L0IC 5C5PC 4L33C 4UI7C 4L2GC 4L09C 4KZQC 4UI4C 4L34C 4L0TC 4L2FC 4HLGC 4UI5C 5ADSB 4HLKC 4HL5C 4L0SC 4UVPB 5ADRB 4L31C 5ADQB 4HKNC 5ADTB 5C5RC 4L0BC
chains in the Genus database with same CATH superfamily
4L32C 5FPFC 4L2KC 4L0VC 4L10C 4UI3C 5C5QC 4HKKB 4HLMC 4HKIC 4HLFC 3KH2E 4HLHC 4KZLC 4UI8C 2ODKA 4ZM2A 4UI6C 3CTOA 3D55A 4HMHC 4KZUC 4L0IC 5C5PC 3G5OA 4L33C 3OEIA 2A6QA 4L2GC 4UI7C 4L09C 4ZM0A 4KZQC 4UI4C 2ZIXB 4L34C 4L0TC 4L2FC 4HLGC 3K33B 4UI5C 5ADSB 4HLKC 4HL5C 4L0SC 4UVPB 5ADRB 3HRYA 4L31C 3K6QA 4HKNC 5ADQB 5ADTB 5C5RC 3OEIE 3HJ6A 3HS2A 4ZLXA 4L0BC
chains in the Genus database with same CATH topology
4L32C 5FPFC 4L2KC 4L0VC 4L10C 4UI3C 5C5QC 4HKKB 4HLMC 4HKIC 4HLFC 4KZLC 4HLHC 4UI8C 4UI6C 4HMHC 4KZUC 4L0IC 5C5PC 4L33C 4UI7C 4L2GC 4L09C 4KZQC 4UI4C 4L34C 4L0TC 4L2FC 4HLGC 4UI5C 5ADSB 4HLKC 4HL5C 4L0SC 4UVPB 5ADRB 4L31C 5ADQB 4HKNC 5ADTB 5C5RC 3HJ6A 2ZIXB 4L0BC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4L32 C;  5FPF C;  4L2K C;  4L0V C;  4L10 C;  4UI3 C;  5C5Q C;  4HKK B;  4HLM C;  4HKI C;  4HLF C;  4KZL C;  4HLH C;  4UI8 C;  4UI6 C;  4HMH C;  4KZU C;  4L0I C;  5C5P C;  4L33 C;  4UI7 C;  4L2G C;  4L09 C;  4KZQ C;  4UI4 C;  4L34 C;  4L0T C;  4L2F C;  4HLG C;  4UI5 C;  5ADS B;  4HLK C;  4HL5 C;  4L0S C;  4UVP B;  5ADR B;  4L31 C;  5ADQ B;  4HKN C;  5ADT B;  5C5R C;  4L0B C; 
#chains in the Genus database with same CATH topology
 4L32 C;  5FPF C;  4L2K C;  4L0V C;  4L10 C;  4UI3 C;  5C5Q C;  4HKK B;  4HLM C;  4HKI C;  4HLF C;  3KH2 E;  4HLH C;  4KZL C;  4UI8 C;  2ODK A;  4ZM2 A;  4UI6 C;  3CTO A;  3D55 A;  4HMH C;  4KZU C;  4L0I C;  5C5P C;  3G5O A;  4L33 C;  3OEI A;  2A6Q A;  4L2G C;  4UI7 C;  4L09 C;  4ZM0 A;  4KZQ C;  4UI4 C;  2ZIX B;  4L34 C;  4L0T C;  4L2F C;  4HLG C;  3K33 B;  4UI5 C;  5ADS B;  4HLK C;  4HL5 C;  4L0S C;  4UVP B;  5ADR B;  3HRY A;  4L31 C;  3K6Q A;  4HKN C;  5ADQ B;  5ADT B;  5C5R C;  3OEI E;  3HJ6 A;  3HS2 A;  4ZLX A;  4L0B C; 
#chains in the Genus database with same CATH homology
 4L32 C;  5FPF C;  4L2K C;  4L0V C;  4L10 C;  4UI3 C;  5C5Q C;  4HKK B;  4HLM C;  4HKI C;  4HLF C;  4KZL C;  4HLH C;  4UI8 C;  4UI6 C;  4HMH C;  4KZU C;  4L0I C;  5C5P C;  4L33 C;  4UI7 C;  4L2G C;  4L09 C;  4KZQ C;  4UI4 C;  4L34 C;  4L0T C;  4L2F C;  4HLG C;  4UI5 C;  5ADS B;  4HLK C;  4HL5 C;  4L0S C;  4UVP B;  5ADR B;  4L31 C;  5ADQ B;  4HKN C;  5ADT B;  5C5R C;  3HJ6 A;  2ZIX B;  4L0B C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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