5ADTB

Crystal structure of human tankyrase 2 in complex with od73
Total Genus 1
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
1
sequence length
46
structure length
46
Chain Sequence
AHSPPGHHSVTGRPSVNGLALAEYVIYRGEQAYPEYLITYQIMRPE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Development and Structural Analysis of Adenosine Site Binding Tankyrase Inhibitors.
pubmed doi rcsb
molecule tags Transferase
source organism Homo sapiens
molecule keywords TANKYRASE-2
total genus 1
structure length 46
sequence length 46
ec nomenclature ec 2.4.2.30: NAD(+) ADP-ribosyltransferase.
pdb deposition date 2015-08-24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1620.50 Alpha Beta 3-Layer(aba) Sandwich YefM-like fold YefM-like fold 5adtB00
4HKKB 4HMHC 4UI3C 4UI6C 4KZQC 5ADQB 4L34C 5FPFC 5C5RC 4L33C 5ADSB 4HLKC 4KZLC 4L0TC 5ADTB 4L10C 4UI5C 4L2GC 4L2KC 4L09C 4UI4C 4HLFC 4KZUC 4L32C 4UI7C 4HLMC 4HKNC 4HLGC 4L0VC 4HKIC 4L0IC 4L2FC 4UI8C 5ADRB 4L0BC 4L31C 5C5PC 4L0SC 4UVPB 4HLHC 4HL5C 5C5QC
chains in the Genus database with same CATH superfamily
4HKKB 4HMHC 3HS2A 3HJ6A 4UI3C 4UI6C 4KZQC 5ADQB 4L34C 3G5OA 5FPFC 5C5RC 4L33C 5ADSB 4HLKC 3CTOA 4KZLC 4L0TC 4ZM2A 4L10C 5ADTB 4UI5C 4L2GC 4L2KC 3K6QA 4L09C 4UI4C 2ODKA 4HLFC 4KZUC 4L32C 3OEIA 3OEIE 4UI7C 4HLMC 4HKNC 4ZM0A 4ZLXA 2ZIXB 3HRYA 4HLGC 4HKIC 4L0VC 4L0IC 2A6QA 4L2FC 4UI8C 5ADRB 3KH2E 4L0BC 3D55A 4L31C 3K33B 5C5PC 4L0SC 4UVPB 4HLHC 4HL5C 5C5QC
chains in the Genus database with same CATH topology
4HKKB 4HMHC 3HJ6A 4UI3C 4UI6C 4KZQC 5ADQB 4L34C 5FPFC 5C5RC 4L33C 5ADSB 4HLKC 4KZLC 4L0TC 5ADTB 4L10C 4UI5C 4L2GC 4L2KC 4L09C 4UI4C 4HLFC 4KZUC 4L32C 4UI7C 4HLMC 4HKNC 2ZIXB 4L0VC 4HKIC 4HLGC 4L0IC 4L2FC 4UI8C 5ADRB 4L0BC 4L31C 5C5PC 4L0SC 4UVPB 4HLHC 4HL5C 5C5QC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4HKK B;  4HMH C;  4UI3 C;  4UI6 C;  4KZQ C;  5ADQ B;  4L34 C;  5FPF C;  5C5R C;  4L33 C;  5ADS B;  4HLK C;  4KZL C;  4L0T C;  5ADT B;  4L10 C;  4UI5 C;  4L2G C;  4L2K C;  4L09 C;  4UI4 C;  4HLF C;  4KZU C;  4L32 C;  4UI7 C;  4HLM C;  4HKN C;  4HLG C;  4L0V C;  4HKI C;  4L0I C;  4L2F C;  4UI8 C;  5ADR B;  4L0B C;  4L31 C;  5C5P C;  4L0S C;  4UVP B;  4HLH C;  4HL5 C;  5C5Q C; 
#chains in the Genus database with same CATH topology
 4HKK B;  4HMH C;  3HS2 A;  3HJ6 A;  4UI3 C;  4UI6 C;  4KZQ C;  5ADQ B;  4L34 C;  3G5O A;  5FPF C;  5C5R C;  4L33 C;  5ADS B;  4HLK C;  3CTO A;  4KZL C;  4L0T C;  4ZM2 A;  4L10 C;  5ADT B;  4UI5 C;  4L2G C;  4L2K C;  3K6Q A;  4L09 C;  4UI4 C;  2ODK A;  4HLF C;  4KZU C;  4L32 C;  3OEI A;  3OEI E;  4UI7 C;  4HLM C;  4HKN C;  4ZM0 A;  4ZLX A;  2ZIX B;  3HRY A;  4HLG C;  4HKI C;  4L0V C;  4L0I C;  2A6Q A;  4L2F C;  4UI8 C;  5ADR B;  3KH2 E;  4L0B C;  3D55 A;  4L31 C;  3K33 B;  5C5P C;  4L0S C;  4UVP B;  4HLH C;  4HL5 C;  5C5Q C; 
#chains in the Genus database with same CATH homology
 4HKK B;  4HMH C;  3HJ6 A;  4UI3 C;  4UI6 C;  4KZQ C;  5ADQ B;  4L34 C;  5FPF C;  5C5R C;  4L33 C;  5ADS B;  4HLK C;  4KZL C;  4L0T C;  5ADT B;  4L10 C;  4UI5 C;  4L2G C;  4L2K C;  4L09 C;  4UI4 C;  4HLF C;  4KZU C;  4L32 C;  4UI7 C;  4HLM C;  4HKN C;  2ZIX B;  4L0V C;  4HKI C;  4HLG C;  4L0I C;  4L2F C;  4UI8 C;  5ADR B;  4L0B C;  4L31 C;  5C5P C;  4L0S C;  4UVP B;  4HLH C;  4HL5 C;  5C5Q C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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