5BP2A

Dehydratase domain (dh) of a mycocerosic acid synthase-like (mas-like) pks, crystal form 1
Total Genus 71
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
71
sequence length
285
structure length
285
Chain Sequence
PSVSVHPLLGSHVVLPQEPEEHLWQGDVGTEAHPWLSDHRVHQVAVLPGAAYCEMALAAVTPVLGDTGEVHDLKFHDMLLLDDATPVWVSAAVTAPGTAEFGVETHQSGDRTQRATAVLRGDVDAERPAAHSIDALLAAHPNRVDGDELRAGFGTVGIGHGAAFAGLSEAYVATAAEPTVVAAVALPGPLRSGQRGYTVHPALLDACFQSVIAHPEVQNIASGMLLPLGVRRLRAYGSTRNVRYCLSRIVKADSFGVEADLELLDADGTVLLSAMGLQLGTGNSD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Mycocerosic acid synthase exemplifies the architecture of reducing polyketide synthases.
pubmed doi rcsb
molecule tags Lyase
source organism Mycobacterium smegmatis
molecule keywords Mycocerosic acid synthase-like polyketide synthase
total genus 71
structure length 285
sequence length 285
chains with identical sequence B, C, D
ec nomenclature ec 2.3.1.-:
pdb deposition date 2015-05-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF14765 PS-DH Polyketide synthase dehydratase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.129.110 Alpha Beta Roll Thiol Ester Dehydrase; Chain A Thiol Ester Dehydrase; Chain A 5bp2A00
3KG9A 2VZ9A 3KG6A 3HRRA 2VZ8A 3KG7A 4OOCA 4U3VA 5BP2A 4KC5A 5BP3A 5KKUA 3HRQA 3EL6A 5E1VA 4LN9A
chains in the Genus database with same CATH superfamily
3KUWA 3DOYA 5SZUA 3P2QA 2EGRA 1Q6WA 4R9ZA 5EP5A 2W3XA 4XY6A 5F6RA 1ZKIA 3DKZA 5T06A 3DP2A 3S4KA 2ESSA 3GEKA 1WN3A 3CK1A 5BUWA 3AZ9A 3R3AA 3CF9A 3ESIA 5KKUA 3KUVA 4RMMA 3E8PA 3CJYA 4MTUA 4R4UA 3ZH5A 1Q4TA 4W78B 3ZH7A 4QD7A 2XEMA 3DP0A 1YOCA 3KV8A 5EGJA 3KHPA 3EL6A 5E1VA 3U0AA 2OKIA 2CYEA 2HBOA 3P3IA 3LW3A 2H4UA 3B7JA 4QFWA 2V1OA 4ZJBA 1C8UA 1LO8A 4NCPA 1Q4UA 4KC5A 2PZHA 3AZ8A 1VH9A 3R3BA 4I45A 4LN9A 3R87A 1WLVA 1MKAA 4W78A 3S6PA 3ZH7B 4CL6A 1VI8A 1YLIA 4K4DA 2EISA 1OHFA 3K67A 3NWZA 1S5UA 2OAFA 3R3DA 4RV2B 4A12A 5EGKA 5EGLA 2FS2A 3R36A 4A0YA 2B3MA 4ZRBA 3HRRA 4B0IA 1WLUA 3D6LA 2O6UA 5DM5A 2OIWA 3LZ7A 5BP3A 2QQPA 3R3CA 3KVUA 2PRXA 3KG8A 1MKBA 3KVZA 4IENA 4K02A 4ZV3A 3KG6A 4YBVA 2GLMA 2F0XA 3LBEA 5HMCA 5BP2A 5HZ4A 4I82A 2AV9A 3P2SA 4KEHA 2C2IA 2EGJA 1SBKA 2F41A 2NUJA 1T82A 3KVIA 4RV2A 5SZZA 4E3EA 4RLJA 2B6EA 5SZVA 4AE7A 4XY5A 3DP3A 4K00A 1ZHGA 3CF8A 3D6XA 4B0CA 5HWFA 1Q4SA 2EGIA 2UV8G 3QOOA 2DSLA 2GLVA 4RLWA 3BJKA 1LO9A 4WNBA 4ZW0A 1Z6BA 2OKHA 3R37A 1PSUA 2GF6A 2GVHA 1NJKA 3OMLA 2XFLA 4OOBA 4B0JA 2HX5A 1PN2A 4MOBA 2VKZG 5T02A 4HZNA 3E29A 3AZAA 3FRNA 4K4BA 4RLJB 4A0ZA 4AE8A 3IR3A 1Y7UA 5BUYA 5BYUA 4I4JA 4ORDA 4K49A 4M20A 4RLWB 2OV9A 1BVQA 2HLJA 3B7KA 3LMBA 4RLUA 4WNBB 3TEAA 1WM6A 2O6BA 3QY3A 4QD9A 1LO7A 2F3XA 3KH8A 3P2RA 4QDAA 2QQ2A 3SPSA 4RLTB 2QWZA 4H4GA 4A0XA 2PFCA 2GLLA 3D04A 4B8UA 3BNVA 1IQ6A 3B18A 3HDUA 3R34A 1J1YA 2O5UA 3KV7A 4B0BA 2CWZA 3LWGA 3Q62A 1IXLA 1VH5A 4GAKA 3LBBA 2PIMA 4I83A 3KX8A 3R3FA 4MZQA 3F5OA 3HMJG 3KG7A 4GAHA 2Q2BA 1S9CA 4FQ9A 1SH8A 4OOCA 4RLUB 4K4CA 3AZBA 3KG9A 3EXZA 3DP1A 4HZPA 4RLTA 3RQBA 1VPMA 2CY9A 2O6TA 3E1EA 3R35A 4QD8A 3BBJA 4MOCA 4K4AA 5KL9A 5EO2A 5DIOA 4QDBA 5HD6A 2VZ8A 2BI0A 5SZYA 3ED0A 5BUXA 3P3FA 5T07A 1Z54A 3DOZA 3RD7A 3WEWA 3HRQA 5HMBA 3R32A 3HM0A 1U1ZA 3F1TA 1SC0A 2OWNA 2VZ9A 4FFUA 3ZH6A 1PN4A 4HZOA 5CPGA 1TBUA 4U3VA 3KX7A 2GLPA 2FUJA 3KW1A 4ZRFA 5EO4A 2Q78A
chains in the Genus database with same CATH topology
3ZH7B 3HMJG 3KG7A 4OOCA 1OHFA 3KG9A 3RQBA 2VKZG 3HRRA 3FRNA 3BBJA 5BP3A 5KKUA 2QQPA 3CJYA 4R4UA 3ZH5A 3ZH7A 3KG8A 3KG6A 2VZ8A 5BP2A 3RD7A 3HRQA 3S6PA 3EL6A 5E1VA 3U0AA 2PFCA 2VZ9A 4QFWA 3ZH6A 3B18A 4U3VA 4KC5A 2UV8G 4LN9A 4R9ZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3KG9 A;  2VZ9 A;  3KG6 A;  3HRR A;  2VZ8 A;  3KG7 A;  4OOC A;  4U3V A;  5BP2 A;  4KC5 A;  5BP3 A;  5KKU A;  3HRQ A;  3EL6 A;  5E1V A;  4LN9 A; 
#chains in the Genus database with same CATH topology
 3KUW A;  3DOY A;  5SZU A;  3P2Q A;  2EGR A;  1Q6W A;  4R9Z A;  5EP5 A;  2W3X A;  4XY6 A;  5F6R A;  1ZKI A;  3DKZ A;  5T06 A;  3DP2 A;  3S4K A;  2ESS A;  3GEK A;  1WN3 A;  3CK1 A;  5BUW A;  3AZ9 A;  3R3A A;  3CF9 A;  3ESI A;  5KKU A;  3KUV A;  4RMM A;  3E8P A;  3CJY A;  4MTU A;  4R4U A;  3ZH5 A;  1Q4T A;  4W78 B;  3ZH7 A;  4QD7 A;  2XEM A;  3DP0 A;  1YOC A;  3KV8 A;  5EGJ A;  3KHP A;  3EL6 A;  5E1V A;  3U0A A;  2OKI A;  2CYE A;  2HBO A;  3P3I A;  3LW3 A;  2H4U A;  3B7J A;  4QFW A;  2V1O A;  4ZJB A;  1C8U A;  1LO8 A;  4NCP A;  1Q4U A;  4KC5 A;  2PZH A;  3AZ8 A;  1VH9 A;  3R3B A;  4I45 A;  4LN9 A;  3R87 A;  1WLV A;  1MKA A;  4W78 A;  3S6P A;  3ZH7 B;  4CL6 A;  1VI8 A;  1YLI A;  4K4D A;  2EIS A;  1OHF A;  3K67 A;  3NWZ A;  1S5U A;  2OAF A;  3R3D A;  4RV2 B;  4A12 A;  5EGK A;  5EGL A;  2FS2 A;  3R36 A;  4A0Y A;  2B3M A;  4ZRB A;  3HRR A;  4B0I A;  1WLU A;  3D6L A;  2O6U A;  5DM5 A;  2OIW A;  3LZ7 A;  5BP3 A;  2QQP A;  3R3C A;  3KVU A;  2PRX A;  3KG8 A;  1MKB A;  3KVZ A;  4IEN A;  4K02 A;  4ZV3 A;  3KG6 A;  4YBV A;  2GLM A;  2F0X A;  3LBE A;  5HMC A;  5BP2 A;  5HZ4 A;  4I82 A;  2AV9 A;  3P2S A;  4KEH A;  2C2I A;  2EGJ A;  1SBK A;  2F41 A;  2NUJ A;  1T82 A;  3KVI A;  4RV2 A;  5SZZ A;  4E3E A;  4RLJ A;  2B6E A;  5SZV A;  4AE7 A;  4XY5 A;  3DP3 A;  4K00 A;  1ZHG A;  3CF8 A;  3D6X A;  4B0C A;  5HWF A;  1Q4S A;  2EGI A;  2UV8 G;  3QOO A;  2DSL A;  2GLV A;  4RLW A;  3BJK A;  1LO9 A;  4WNB A;  4ZW0 A;  1Z6B A;  2OKH A;  3R37 A;  1PSU A;  2GF6 A;  2GVH A;  1NJK A;  3OML A;  2XFL A;  4OOB A;  4B0J A;  2HX5 A;  1PN2 A;  4MOB A;  2VKZ G;  5T02 A;  4HZN A;  3E29 A;  3AZA A;  3FRN A;  4K4B A;  4RLJ B;  4A0Z A;  4AE8 A;  3IR3 A;  1Y7U A;  5BUY A;  5BYU A;  4I4J A;  4ORD A;  4K49 A;  4M20 A;  4RLW B;  2OV9 A;  1BVQ A;  2HLJ A;  3B7K A;  3LMB A;  4RLU A;  4WNB B;  3TEA A;  1WM6 A;  2O6B A;  3QY3 A;  4QD9 A;  1LO7 A;  2F3X A;  3KH8 A;  3P2R A;  4QDA A;  2QQ2 A;  3SPS A;  4RLT B;  2QWZ A;  4H4G A;  4A0X A;  2PFC A;  2GLL A;  3D04 A;  4B8U A;  3BNV A;  1IQ6 A;  3B18 A;  3HDU A;  3R34 A;  1J1Y A;  2O5U A;  3KV7 A;  4B0B A;  2CWZ A;  3LWG A;  3Q62 A;  1IXL A;  1VH5 A;  4GAK A;  3LBB A;  2PIM A;  4I83 A;  3KX8 A;  3R3F A;  4MZQ A;  3F5O A;  3HMJ G;  3KG7 A;  4GAH A;  2Q2B A;  1S9C A;  4FQ9 A;  1SH8 A;  4OOC A;  4RLU B;  4K4C A;  3AZB A;  3KG9 A;  3EXZ A;  3DP1 A;  4HZP A;  4RLT A;  3RQB A;  1VPM A;  2CY9 A;  2O6T A;  3E1E A;  3R35 A;  4QD8 A;  3BBJ A;  4MOC A;  4K4A A;  5KL9 A;  5EO2 A;  5DIO A;  4QDB A;  5HD6 A;  2VZ8 A;  2BI0 A;  5SZY A;  3ED0 A;  5BUX A;  3P3F A;  5T07 A;  1Z54 A;  3DOZ A;  3RD7 A;  3WEW A;  3HRQ A;  5HMB A;  3R32 A;  3HM0 A;  1U1Z A;  3F1T A;  1SC0 A;  2OWN A;  2VZ9 A;  4FFU A;  3ZH6 A;  1PN4 A;  4HZO A;  5CPG A;  1TBU A;  4U3V A;  3KX7 A;  2GLP A;  2FUJ A;  3KW1 A;  4ZRF A;  5EO4 A;  2Q78 A; 
#chains in the Genus database with same CATH homology
 3ZH7 B;  3HMJ G;  3KG7 A;  4OOC A;  1OHF A;  3KG9 A;  3RQB A;  2VKZ G;  3HRR A;  3FRN A;  3BBJ A;  5BP3 A;  5KKU A;  2QQP A;  3CJY A;  4R4U A;  3ZH5 A;  3ZH7 A;  3KG8 A;  3KG6 A;  2VZ8 A;  5BP2 A;  3RD7 A;  3HRQ A;  3S6P A;  3EL6 A;  5E1V A;  3U0A A;  2PFC A;  2VZ9 A;  4QFW A;  3ZH6 A;  3B18 A;  4U3V A;  4KC5 A;  2UV8 G;  4LN9 A;  4R9Z A; 
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