5C4XF

Crystal structure of a transcribing rna polymerase ii complex reveals a complete transcription bubble
Total Genus 20
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
20
sequence length
87
structure length
87
Chain Sequence
LKEKAIPKDQRATTPYMTKYERARILGTRALQISMNAPVFVDLEGETDPLRIAMKELAEKKIPLVIRRYLPDGSFEDWSVEELIVDL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of a Transcribing RNA Polymerase II Complex Reveals a Complete Transcription Bubble.
pubmed doi rcsb
molecule tags Transferase/rna/dna
source organism Saccharomyces cerevisiae (strain atcc 204508 / s288c)
molecule keywords DNA-directed RNA polymerase II subunit RPB1
total genus 20
structure length 87
sequence length 87
ec nomenclature
pdb deposition date 2015-06-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
F PF01192 RNA_pol_Rpb6 RNA polymerase Rpb6
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.940.10 Alpha Beta Alpha-Beta Complex Eukaryotic RPB6 RNA polymerase subunit Eukaryotic RPB6 RNA polymerase subunit 5c4xF00
4Q5SE 5IPLE 3WODE 5C4JF 4A3FF 3S1QF 5IP7F 4A3CF 3K7AF 2BE5E 1I6HF 4G7OE 5FJ8F 3RZDF 5IYCF 4A3EF 1IW7E 3S14F 4YG2E 3PO2F 1SMYE 4MEYE 1TWGF 3S1MF 3RZOF 5IYBF 4MEXE 4OIOE 3FKIF 5C3EF 5D4EE 2O5IE 5M3MF 4MQ9E 3GTMF 3HOVF 3I4MF 4G7HE 4LJZE 3S16F 3GTQF 4OINE 1QKLA 3HOYF 4XSXE 4C3JF 2JA8F 4AYBK 4C3IF 2PMZK 4A3KF 4BY1F 3H0GF 1WCMF 4KMUE 2JA7F 4YFXE 5IYDF 3H3VG 4JK1E 1YNJK 3HOWF 1YNNK 2Y0SI 2JA5F 2YU9F 4OIPE 3HOZF 4BY7F 2NVTF 4A3IF 1K83F 4X6AF 3GTKF 5M5XF 3S15F 4YFKE 4C2MF 3EQLE 4G7ZE 2E2IF 2R92F 3GTOF 4KN7E 4YFNE 4A3GF 5M3FF 2O5JE 3GTPF 4GZYE 1R9TF 3GTLF 3HOUF 5D4DE 2PPBE 3S1NF 5E17E 3M4OF 3M3YF 3CQZF 4A3JF 3HOXF 4BBRF 2NVYF 2A69E 3I4NF 2CW0E 3HKZK 1SFOF 1I6VE 4LLGE 4C3HF 4KN4E 3GTJF 2WAQK 4A3LF 2A68E 4BBSF 1HQME 4ZH4E 4Y7NF 5TMCE 4XSZE 2R93F 2A6EE 4XLPE 4OIRE 4A3MF 2JA6F 3S2DF 2VUMF 4A93F 2A6HE 1ZYRE 2B63F 5FLMF 4OIQE 2E2JF 4Y52F 5E18E 4LK1E 1TWAF 3DXJE 5TMFE 1TWHF 1Y1WF 1TWCF 2R7ZF 4LK0E 5D4CE 2NVQF 2WB1I 4XLNE 2NVXF 3S17F 4A3DF 4Q4ZE 3S1RF 1TWFF 5IP9F 5M5WF 5BYHE 4BXXF 5M5YF 3GTGF 1I3QF 3S2HF 5C44F 1Y1VF 2E2HF 3PO3F 4A3BF 1I50F 5C4XF
chains in the Genus database with same CATH superfamily
4Q5SE 2JA7E 5IYDE 5IPLE 3WODE 5C4JF 4A3FF 3S1QF 5IP7F 4A3CF 1SFOE 3K7AF 2BE5E 4C3HE 1I6HF 4G7OE 5FJ8F 2JA5E 3RZDF 5IYCF 4BBSE 4BY7E 4A3EF 1IW7E 4Y7NE 2NVTE 4YG2E 3S14F 3PO2F 1SMYE 1K83E 4MEYE 2R93E 5M5XE 4A3ME 3S15E 2VUME 1TWGF 4A93E 3S1MF 3RZOF 2E2IE 5IYBF 4MEXE 4OIOE 2B63E 3GTOE 2R92E 3FKIF 5C3EF 5D4EE 2E2JE 2O5IE 5M3MF 4MQ9E 3GTMF 3HOVF 4A3GE 3I4MF 5M3FE 4Y52E 4G7HE 4LJZE 1R9TE 3S16F 3GTQF 1Y1WE 1TWCE 3S1NE 4OINE 1QKLA 3HOYF 3M3YE 4XSXE 4C3JF 3HOXE 4BBRE 2JA8F 4AYBK 4C3IF 2NVYE 2PMZK 3I4NE 3S17E 4A3KF 4BY1F 3H0GF 3S1RE 3HKZH 1EIKA 1WCMF 4KMUE 3GTJE 2JA7F 4YFXE 5IYDF 3H3VG 4A3LE 2WAQH 4JK1E 1YNJK 3HOWF 1TWFE 1YNNK 5IP9E 5M5YE 2Y0SI 3GTGE 2JA5F 2YU9F 4OIPE 3HOZF 4BY7F 2NVTF 2JA6E 3S2DE 4A3IF 2Y0SH 1K83F 4QIWH 1I50E 4X6AF 3GTKF 5FLME 5M5XF 3S15F 4YFKE 4C2MF 5C4JE 4A3CE 3EQLE 5IP7E 4G7ZE 2E2IF 2R92F 3GTOF 1TWAE 4KN7E 1TWHE 4YFNE 4A3GF 5M3FF 2O5JE 2R7ZE 3GTPF 4GZYE 1R9TF 2NVQE 4A3EE 3GTLF 2NVXE 5D4DE 2PPBE 3HOUF 3S1NF 4A3DE 3M4OF 5E17E 3M3YF 3CQZF 4A3JF 3HOXF 4BBRF 1TWGE 2NVYF 2A69E 3I4NF 3RZOE 5IYBE 3S1ME 2CW0E 3HKZK 1SFOF 3FKIE 5C3EE 4BXXE 1I6VE 5M5WE 5M3ME 4LLGE 4C3HF 4KN4E 3GTJF 2WAQK 3I4ME 4A3LF 1I3QE 2A68E 3S2HE 5C44E 1Y1VE 2E2HE 4BBSF 3GTQE 3PO3E 1HQME 4ZH4E 4Y7NF 4A3BE 5TMCE 2KRXA 3H3VF 4XSZE 2R93F 2A6EE 4XLPE 4OIRE 2JA8E 4A3MF 2JA6F 3S2DF 5C4XE 4QIWK 2VUMF 4A3FE 2A6HE 3S1QE 4A93F 1ZYRE 4A3KE 4BY1E 3H0GE 3K7AE 5FLMF 4OIQE 2B63F 2E2JF 1I6HE 5FJ8E 4Y52F 5E18E 3RZDE 4LK1E 5IYCE 3HOWE 1TWAF 3DXJE 5TMFE 3S14E 1TWHF 1Y1WF 1TWCF 3PO2E 2YU9E 2R7ZF 3HOZE 4LK0E 5D4CE 2NVQF 2WB1I 4XLNE 4A3IE 2NVXF 1DZFA 3S17F 4X6AE 4A3DF 3GTKE 4Q4ZE 3S1RF 2WB1H 3GTME 3HOVE 4C2ME 1TWFF 5IP9F 5BYHE 5M5WF 3S16E 4BXXF 5M5YF 3GTGF 3GTPE 1I3QF 3HOYE 3S2HF 5C44F 1Y1VF 2E2HF 4C3JE 3GTLE 4C3IE 3HOUE 4A3BF 4AYBH 3PO3F 2PMZH 3M4OE 1I50F 3CQZE 4A3JE 1WCME 5C4XF
chains in the Genus database with same CATH topology
4Q5SE 5IPLE 3WODE 5C4JF 4A3FF 3S1QF 5IP7F 4A3CF 3K7AF 2BE5E 1I6HF 4G7OE 5FJ8F 3RZDF 5IYCF 4A3EF 1IW7E 3S14F 4YG2E 3PO2F 1SMYE 4MEYE 1TWGF 3S1MF 3RZOF 5IYBF 4MEXE 4OIOE 3FKIF 5C3EF 5D4EE 2O5IE 5M3MF 4MQ9E 3GTMF 3HOVF 3I4MF 4G7HE 4LJZE 3S16F 3GTQF 4OINE 1QKLA 3HOYF 4XSXE 4C3JF 2JA8F 4AYBK 4C3IF 2PMZK 4A3KF 4BY1F 3H0GF 1WCMF 4KMUE 2JA7F 4YFXE 5IYDF 3H3VG 4JK1E 1YNJK 3HOWF 1YNNK 2Y0SI 2JA5F 2YU9F 4OIPE 3HOZF 4BY7F 2NVTF 4A3IF 1K83F 4X6AF 3GTKF 5M5XF 3S15F 4YFKE 4C2MF 3EQLE 4G7ZE 2E2IF 2R92F 3GTOF 4KN7E 4YFNE 4A3GF 5M3FF 2O5JE 3GTPF 4GZYE 1R9TF 3GTLF 3HOUF 5D4DE 2PPBE 3S1NF 5E17E 3M4OF 3M3YF 3CQZF 4A3JF 3HOXF 4BBRF 2NVYF 2A69E 3I4NF 2CW0E 3HKZK 1SFOF 1I6VE 4LLGE 4C3HF 4KN4E 3GTJF 2WAQK 4A3LF 2A68E 4BBSF 1HQME 4ZH4E 4Y7NF 5TMCE 2KRXA 4XSZE 2R93F 2A6EE 4XLPE 4OIRE 4A3MF 2JA6F 3S2DF 4QIWK 2VUMF 4A93F 2A6HE 1ZYRE 2B63F 5FLMF 4OIQE 2E2JF 4Y52F 5E18E 4LK1E 1TWAF 3DXJE 5TMFE 1TWHF 1Y1WF 1TWCF 2R7ZF 4LK0E 5D4CE 2NVQF 2WB1I 4XLNE 2NVXF 3S17F 4A3DF 4Q4ZE 3S1RF 1TWFF 5IP9F 5M5WF 5BYHE 4BXXF 5M5YF 3GTGF 1I3QF 3S2HF 5C44F 1Y1VF 2E2HF 3PO3F 4A3BF 1I50F 5C4XF
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4Q5S E;  5IPL E;  3WOD E;  5C4J F;  4A3F F;  3S1Q F;  5IP7 F;  4A3C F;  3K7A F;  2BE5 E;  1I6H F;  4G7O E;  5FJ8 F;  3RZD F;  5IYC F;  4A3E F;  1IW7 E;  3S14 F;  4YG2 E;  3PO2 F;  1SMY E;  4MEY E;  1TWG F;  3S1M F;  3RZO F;  5IYB F;  4MEX E;  4OIO E;  3FKI F;  5C3E F;  5D4E E;  2O5I E;  5M3M F;  4MQ9 E;  3GTM F;  3HOV F;  3I4M F;  4G7H E;  4LJZ E;  3S16 F;  3GTQ F;  4OIN E;  1QKL A;  3HOY F;  4XSX E;  4C3J F;  2JA8 F;  4AYB K;  4C3I F;  2PMZ K;  4A3K F;  4BY1 F;  3H0G F;  1WCM F;  4KMU E;  2JA7 F;  4YFX E;  5IYD F;  3H3V G;  4JK1 E;  1YNJ K;  3HOW F;  1YNN K;  2Y0S I;  2JA5 F;  2YU9 F;  4OIP E;  3HOZ F;  4BY7 F;  2NVT F;  4A3I F;  1K83 F;  4X6A F;  3GTK F;  5M5X F;  3S15 F;  4YFK E;  4C2M F;  3EQL E;  4G7Z E;  2E2I F;  2R92 F;  3GTO F;  4KN7 E;  4YFN E;  4A3G F;  5M3F F;  2O5J E;  3GTP F;  4GZY E;  1R9T F;  3GTL F;  3HOU F;  5D4D E;  2PPB E;  3S1N F;  5E17 E;  3M4O F;  3M3Y F;  3CQZ F;  4A3J F;  3HOX F;  4BBR F;  2NVY F;  2A69 E;  3I4N F;  2CW0 E;  3HKZ K;  1SFO F;  1I6V E;  4LLG E;  4C3H F;  4KN4 E;  3GTJ F;  2WAQ K;  4A3L F;  2A68 E;  4BBS F;  1HQM E;  4ZH4 E;  4Y7N F;  5TMC E;  4XSZ E;  2R93 F;  2A6E E;  4XLP E;  4OIR E;  4A3M F;  2JA6 F;  3S2D F;  2VUM F;  4A93 F;  2A6H E;  1ZYR E;  2B63 F;  5FLM F;  4OIQ E;  2E2J F;  4Y52 F;  5E18 E;  4LK1 E;  1TWA F;  3DXJ E;  5TMF E;  1TWH F;  1Y1W F;  1TWC F;  2R7Z F;  4LK0 E;  5D4C E;  2NVQ F;  2WB1 I;  4XLN E;  2NVX F;  3S17 F;  4A3D F;  4Q4Z E;  3S1R F;  1TWF F;  5IP9 F;  5M5W F;  5BYH E;  4BXX F;  5M5Y F;  3GTG F;  1I3Q F;  3S2H F;  5C44 F;  1Y1V F;  2E2H F;  3PO3 F;  4A3B F;  1I50 F;  5C4X F; 
#chains in the Genus database with same CATH topology
 4Q5S E;  2JA7 E;  5IYD E;  5IPL E;  3WOD E;  5C4J F;  4A3F F;  3S1Q F;  5IP7 F;  4A3C F;  1SFO E;  3K7A F;  2BE5 E;  4C3H E;  1I6H F;  4G7O E;  5FJ8 F;  2JA5 E;  3RZD F;  5IYC F;  4BBS E;  4BY7 E;  4A3E F;  1IW7 E;  4Y7N E;  2NVT E;  4YG2 E;  3S14 F;  3PO2 F;  1SMY E;  1K83 E;  4MEY E;  2R93 E;  5M5X E;  4A3M E;  3S15 E;  2VUM E;  1TWG F;  4A93 E;  3S1M F;  3RZO F;  2E2I E;  5IYB F;  4MEX E;  4OIO E;  2B63 E;  3GTO E;  2R92 E;  3FKI F;  5C3E F;  5D4E E;  2E2J E;  2O5I E;  5M3M F;  4MQ9 E;  3GTM F;  3HOV F;  4A3G E;  3I4M F;  5M3F E;  4Y52 E;  4G7H E;  4LJZ E;  1R9T E;  3S16 F;  3GTQ F;  1Y1W E;  1TWC E;  3S1N E;  4OIN E;  1QKL A;  3HOY F;  3M3Y E;  4XSX E;  4C3J F;  3HOX E;  4BBR E;  2JA8 F;  4AYB K;  4C3I F;  2NVY E;  2PMZ K;  3I4N E;  3S17 E;  4A3K F;  4BY1 F;  3H0G F;  3S1R E;  3HKZ H;  1EIK A;  1WCM F;  4KMU E;  3GTJ E;  2JA7 F;  4YFX E;  5IYD F;  3H3V G;  4A3L E;  2WAQ H;  4JK1 E;  1YNJ K;  3HOW F;  1TWF E;  1YNN K;  5IP9 E;  5M5Y E;  2Y0S I;  3GTG E;  2JA5 F;  2YU9 F;  4OIP E;  3HOZ F;  4BY7 F;  2NVT F;  2JA6 E;  3S2D E;  4A3I F;  2Y0S H;  1K83 F;  4QIW H;  1I50 E;  4X6A F;  3GTK F;  5FLM E;  5M5X F;  3S15 F;  4YFK E;  4C2M F;  5C4J E;  4A3C E;  3EQL E;  5IP7 E;  4G7Z E;  2E2I F;  2R92 F;  3GTO F;  1TWA E;  4KN7 E;  1TWH E;  4YFN E;  4A3G F;  5M3F F;  2O5J E;  2R7Z E;  3GTP F;  4GZY E;  1R9T F;  2NVQ E;  4A3E E;  3GTL F;  2NVX E;  5D4D E;  2PPB E;  3HOU F;  3S1N F;  4A3D E;  3M4O F;  5E17 E;  3M3Y F;  3CQZ F;  4A3J F;  3HOX F;  4BBR F;  1TWG E;  2NVY F;  2A69 E;  3I4N F;  3RZO E;  5IYB E;  3S1M E;  2CW0 E;  3HKZ K;  1SFO F;  3FKI E;  5C3E E;  4BXX E;  1I6V E;  5M5W E;  5M3M E;  4LLG E;  4C3H F;  4KN4 E;  3GTJ F;  2WAQ K;  3I4M E;  4A3L F;  1I3Q E;  2A68 E;  3S2H E;  5C44 E;  1Y1V E;  2E2H E;  4BBS F;  3GTQ E;  3PO3 E;  1HQM E;  4ZH4 E;  4Y7N F;  4A3B E;  5TMC E;  2KRX A;  3H3V F;  4XSZ E;  2R93 F;  2A6E E;  4XLP E;  4OIR E;  2JA8 E;  4A3M F;  2JA6 F;  3S2D F;  5C4X E;  4QIW K;  2VUM F;  4A3F E;  2A6H E;  3S1Q E;  4A93 F;  1ZYR E;  4A3K E;  4BY1 E;  3H0G E;  3K7A E;  5FLM F;  4OIQ E;  2B63 F;  2E2J F;  1I6H E;  5FJ8 E;  4Y52 F;  5E18 E;  3RZD E;  4LK1 E;  5IYC E;  3HOW E;  1TWA F;  3DXJ E;  5TMF E;  3S14 E;  1TWH F;  1Y1W F;  1TWC F;  3PO2 E;  2YU9 E;  2R7Z F;  3HOZ E;  4LK0 E;  5D4C E;  2NVQ F;  2WB1 I;  4XLN E;  4A3I E;  2NVX F;  1DZF A;  3S17 F;  4X6A E;  4A3D F;  3GTK E;  4Q4Z E;  3S1R F;  2WB1 H;  3GTM E;  3HOV E;  4C2M E;  1TWF F;  5IP9 F;  5BYH E;  5M5W F;  3S16 E;  4BXX F;  5M5Y F;  3GTG F;  3GTP E;  1I3Q F;  3HOY E;  3S2H F;  5C44 F;  1Y1V F;  2E2H F;  4C3J E;  3GTL E;  4C3I E;  3HOU E;  4A3B F;  4AYB H;  3PO3 F;  2PMZ H;  3M4O E;  1I50 F;  3CQZ E;  4A3J E;  1WCM E;  5C4X F; 
#chains in the Genus database with same CATH homology
 4Q5S E;  5IPL E;  3WOD E;  5C4J F;  4A3F F;  3S1Q F;  5IP7 F;  4A3C F;  3K7A F;  2BE5 E;  1I6H F;  4G7O E;  5FJ8 F;  3RZD F;  5IYC F;  4A3E F;  1IW7 E;  3S14 F;  4YG2 E;  3PO2 F;  1SMY E;  4MEY E;  1TWG F;  3S1M F;  3RZO F;  5IYB F;  4MEX E;  4OIO E;  3FKI F;  5C3E F;  5D4E E;  2O5I E;  5M3M F;  4MQ9 E;  3GTM F;  3HOV F;  3I4M F;  4G7H E;  4LJZ E;  3S16 F;  3GTQ F;  4OIN E;  1QKL A;  3HOY F;  4XSX E;  4C3J F;  2JA8 F;  4AYB K;  4C3I F;  2PMZ K;  4A3K F;  4BY1 F;  3H0G F;  1WCM F;  4KMU E;  2JA7 F;  4YFX E;  5IYD F;  3H3V G;  4JK1 E;  1YNJ K;  3HOW F;  1YNN K;  2Y0S I;  2JA5 F;  2YU9 F;  4OIP E;  3HOZ F;  4BY7 F;  2NVT F;  4A3I F;  1K83 F;  4X6A F;  3GTK F;  5M5X F;  3S15 F;  4YFK E;  4C2M F;  3EQL E;  4G7Z E;  2E2I F;  2R92 F;  3GTO F;  4KN7 E;  4YFN E;  4A3G F;  5M3F F;  2O5J E;  3GTP F;  4GZY E;  1R9T F;  3GTL F;  3HOU F;  5D4D E;  2PPB E;  3S1N F;  5E17 E;  3M4O F;  3M3Y F;  3CQZ F;  4A3J F;  3HOX F;  4BBR F;  2NVY F;  2A69 E;  3I4N F;  2CW0 E;  3HKZ K;  1SFO F;  1I6V E;  4LLG E;  4C3H F;  4KN4 E;  3GTJ F;  2WAQ K;  4A3L F;  2A68 E;  4BBS F;  1HQM E;  4ZH4 E;  4Y7N F;  5TMC E;  2KRX A;  4XSZ E;  2R93 F;  2A6E E;  4XLP E;  4OIR E;  4A3M F;  2JA6 F;  3S2D F;  4QIW K;  2VUM F;  4A93 F;  2A6H E;  1ZYR E;  2B63 F;  5FLM F;  4OIQ E;  2E2J F;  4Y52 F;  5E18 E;  4LK1 E;  1TWA F;  3DXJ E;  5TMF E;  1TWH F;  1Y1W F;  1TWC F;  2R7Z F;  4LK0 E;  5D4C E;  2NVQ F;  2WB1 I;  4XLN E;  2NVX F;  3S17 F;  4A3D F;  4Q4Z E;  3S1R F;  1TWF F;  5IP9 F;  5M5W F;  5BYH E;  4BXX F;  5M5Y F;  3GTG F;  1I3Q F;  3S2H F;  5C44 F;  1Y1V F;  2E2H F;  3PO3 F;  4A3B F;  1I50 F;  5C4X F; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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