5D4DE

Crystal structure of thermus thermophilus product complex for transcription initiation with nad and ctp
Total Genus 24
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
24
sequence length
94
structure length
94
Chain Sequence
AEPGIDKLFGMVDSKYRLTVVVAKRAQQLLRHGFKNTVLEPEERPKMQTLEGLFDDPNAVTWAMKELLTGRLVFGENLVPEDRLQKEMERLYPV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The mechanism of RNA 5' capping with NAD(+), NADH and desphospho-CoA.
pubmed doi rcsb
molecule tags Transcription/dna
source organism Thermus thermophilus (strain hb27 / atcc baa-163 / dsm 7039)
molecule keywords DNA-directed RNA polymerase subunit alpha
total genus 24
structure length 94
sequence length 94
chains with identical sequence O
ec nomenclature ec 2.7.7.6: DNA-directed RNA polymerase.
pdb deposition date 2015-08-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF01192 RNA_pol_Rpb6 RNA polymerase Rpb6
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.940.10 Alpha Beta Alpha-Beta Complex Eukaryotic RPB6 RNA polymerase subunit Eukaryotic RPB6 RNA polymerase subunit 5d4dE00
1I6HF 1Y1VF 4KN7E 2WB1I 2NVXF 2JA5F 4YG2E 4ZH4E 3WODE 5M3MF 5M5XF 5C44F 4C2MF 4OIQE 3H3VG 1TWHF 3S2HF 5E17E 4A3EF 3FKIF 2NVTF 1IW7E 3S16F 3CQZF 3HOVF 3HOXF 5M5YF 4Q5SE 1K83F 1SMYE 2A6EE 3HKZK 4G7HE 3GTQF 3S14F 3S2DF 3PO3F 1YNNK 4OIPE 2E2HF 5D4CE 4Q4ZE 5IYBF 4LLGE 1YNJK 2PPBE 2YU9F 2O5IE 1TWGF 5C4JF 4BXXF 2WAQK 3PO2F 2O5JE 4A3CF 3M3YF 1TWAF 4A3BF 3GTMF 3S1QF 3HOWF 1TWFF 2JA7F 3RZDF 5M3FF 3I4NF 2R92F 4LK0E 4A3JF 4A93F 4YFNE 4A3GF 3S1NF 4MEYE 2R93F 3K7AF 4A3MF 4YFXE 1WCMF 4BY1F 3HOZF 1ZYRE 4C3HF 4XLNE 3S17F 4JK1E 3GTKF 4A3DF 2VUMF 1TWCF 5IYDF 2A69E 4A3IF 4C3IF 2E2JF 1I50F 3I4MF 2B63F 1SFOF 5FJ8F 5FLMF 5C3EF 3DXJE 4G7OE 5M5WF 3HOYF 2NVYF 2E2IF 3GTJF 5TMFE 5D4DE 3RZOF 2JA6F 4OIOE 4MEXE 4KN4E 4G7ZE 5IYCF 5D4EE 1R9TF 2A6HE 4A3KF 2JA8F 3GTOF 2CW0E 4XLPE 5C4XF 1I6VE 5TMCE 2PMZK 4A3FF 2NVQF 3GTLF 2R7ZF 3H0GF 2Y0SI 4AYBK 5BYHE 1Y1WF 3S1RF 4OINE 4A3LF 3S15F 3EQLE 5IP9F 4Y7NF 4OIRE 4XSXE 3GTGF 4GZYE 4LK1E 4YFKE 4XSZE 4Y52F 4BBRF 3GTPF 4KMUE 2BE5E 5IP7F 4LJZE 5IPLE 5E18E 2A68E 3HOUF 4X6AF 1HQME 4C3JF 1I3QF 3S1MF 4BBSF 3M4OF 4BY7F 1QKLA 4MQ9E
chains in the Genus database with same CATH superfamily
2JA7E 3RZDE 1Y1VF 4KN7E 1I6HF 2WB1I 5M3FE 2NVXF 2JA5F 4YG2E 4ZH4E 3WODE 5M3MF 5M5XF 5C44F 3H3VF 3I4NE 2R92E 4A3JE 4C2MF 4OIQE 3H3VG 4A93E 1TWHF 3S1NE 4A3GE 3S2HF 1TWFE 5E17E 2WAQH 2R93E 3K7AE 4A3EF 4A3ME 3FKIF 1WCME 2NVTF 4BY1E 1IW7E 3S16F 3HOZE 4C3HE 3S17E 3CQZF 3GTKE 3HOVF 4A3DE 3HOXF 2VUME 1TWCE 5IYDE 4Q5SE 5M5YF 4A3IE 1K83F 4C3IE 1SMYE 2A6EE 3HKZK 4G7HE 2E2JE 3GTQF 3S14F 3S2DF 1I50E 3PO3F 1YNNK 4OIPE 3I4ME 2E2HF 2NVXE 2B63E 5D4CE 4Q4ZE 5IYBF 4LLGE 1YNJK 5FJ8E 5FLME 5C3EE 1SFOE 2PPBE 1TWGF 5M5WE 5C4JF 2O5IE 3HOYE 2WAQK 2NVYE 4BXXF 3PO2F 2E2IE 2O5JE 3HKZH 4A3CF 3M3YF 1TWAF 4A3BF 3GTMF 3GTJE 3S1QF 3HOWF 1TWFF 2JA6E 3RZOE 2JA7F 3RZDF 5M3FF 5IYCE 1R9TE 3I4NF 4A3KE 2R92F 4LK0E 3GTOE 2KRXA 4A3JF 5C4XE 4A3FE 3GTLE 2NVQE 4YFNE 2R7ZE 3S1NF 3H0GE 4A93F 4A3GF 4MEYE 2Y0SH 2R93F 3K7AF 4A3MF 4YFXE 1WCMF 1Y1WE 4BY1F 3S1RE 3HOZF 4C3HF 4XLNE 3S17F 4JK1E 3GTKF 4A3LE 3S15E 4A3DF 2VUMF 1TWCF 5IYDF 2A69E 4A3IF 4C3IF 2E2JF 5IP9E 4Y7NE 1I50F 3GTGE 3I4MF 2B63F 3GTPE 4BBRE 4Y52E 1SFOF 2PMZH 5FJ8F 5FLMF 5C3EF 3DXJE 5IP7E 5M5WF 4G7OE 3HOYF 2NVYF 2E2IF 3HOUE 4X6AE 4C3JE 4QIWH 1I3QE 3S1ME 3GTJF 3M4OE 5TMFE 4BBSE 5D4DE 3RZOF 2JA6F 4BY7E 4A3EE 2JA8E 4OIOE 1I6HE 1Y1VE 1DZFA 4MEXE 2WB1H 4KN4E 4G7ZE 5IYCF 5D4EE 1R9TF 2A6HE 4A3KF 5M5XE 5C44E 2JA5E 5M3ME 2JA8F 3GTOF 2CW0E 4XLPE 5C4XF 1I6VE 5TMCE 2PMZK 4C2ME 4A3FF 2NVQF 3GTLF 2R7ZF 3H0GF 1TWHE 3S2HE 2Y0SI 3FKIE 4AYBK 5BYHE 1Y1WF 2NVTE 3S1RF 4QIWK 3S16E 4OINE 3CQZE 4BY7F 3HOVE 3S15F 4A3LF 3HOXE 5M5YE 1K83E 3EQLE 5IP9F 3GTQE 3S14E 4Y7NF 4OIRE 3S2DE 4XSXE 3GTGF 4GZYE 3PO3E 4AYBH 4LK1E 4YFKE 4XSZE 2E2HE 4Y52F 4BBRF 3GTPF 4KMUE 2YU9F 5IYBE 2YU9E 2BE5E 1EIKA 5IP7F 4LJZE 1TWGE 5C4JE 5E18E 4BXXE 5IPLE 2A68E 3PO2E 4A3CE 3HOUF 3M3YE 1TWAE 4A3BE 4X6AF 1HQME 4C3JF 1I3QF 3S1MF 4BBSF 3GTME 3M4OF 3S1QE 3HOWE 1ZYRE 1QKLA 4MQ9E
chains in the Genus database with same CATH topology
1I6HF 1Y1VF 4KN7E 2WB1I 2NVXF 2JA5F 4YG2E 4ZH4E 3WODE 5M3MF 5M5XF 5C44F 4C2MF 4OIQE 3H3VG 1TWHF 3S2HF 5E17E 4A3EF 3FKIF 2NVTF 1IW7E 3S16F 3CQZF 3HOVF 3HOXF 5M5YF 4Q5SE 1K83F 1SMYE 2A6EE 3HKZK 4G7HE 3GTQF 3S14F 3S2DF 3PO3F 1YNNK 4OIPE 2E2HF 5D4CE 4Q4ZE 5IYBF 4LLGE 1YNJK 2PPBE 2YU9F 2O5IE 1TWGF 5C4JF 4BXXF 2WAQK 3PO2F 2O5JE 4A3CF 3M3YF 1TWAF 4A3BF 3GTMF 3S1QF 3HOWF 1TWFF 2JA7F 3RZDF 5M3FF 3I4NF 2R92F 4LK0E 2KRXA 4A3JF 4A93F 4YFNE 4A3GF 3S1NF 4MEYE 2R93F 3K7AF 4A3MF 4YFXE 1WCMF 4BY1F 3HOZF 1ZYRE 4C3HF 4XLNE 3S17F 4JK1E 3GTKF 4A3DF 2VUMF 1TWCF 5IYDF 2A69E 4A3IF 4C3IF 2E2JF 1I50F 3I4MF 2B63F 1SFOF 5FJ8F 5FLMF 5C3EF 3DXJE 4G7OE 5M5WF 3HOYF 2NVYF 2E2IF 3GTJF 5TMFE 5D4DE 3RZOF 2JA6F 4OIOE 4MEXE 4KN4E 4G7ZE 5IYCF 5D4EE 1R9TF 2A6HE 4A3KF 2JA8F 3GTOF 2CW0E 4XLPE 5C4XF 1I6VE 5TMCE 2PMZK 4A3FF 2NVQF 3GTLF 2R7ZF 3H0GF 2Y0SI 4AYBK 5BYHE 1Y1WF 3S1RF 4QIWK 4OINE 4A3LF 3S15F 3EQLE 5IP9F 4Y7NF 4OIRE 4XSXE 3GTGF 4GZYE 4LK1E 4YFKE 4XSZE 4Y52F 4BBRF 3GTPF 4KMUE 2BE5E 5IP7F 4LJZE 5IPLE 5E18E 2A68E 3HOUF 4X6AF 1HQME 4C3JF 1I3QF 3S1MF 4BBSF 3M4OF 4BY7F 1QKLA 4MQ9E
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1I6H F;  1Y1V F;  4KN7 E;  2WB1 I;  2NVX F;  2JA5 F;  4YG2 E;  4ZH4 E;  3WOD E;  5M3M F;  5M5X F;  5C44 F;  4C2M F;  4OIQ E;  3H3V G;  1TWH F;  3S2H F;  5E17 E;  4A3E F;  3FKI F;  2NVT F;  1IW7 E;  3S16 F;  3CQZ F;  3HOV F;  3HOX F;  5M5Y F;  4Q5S E;  1K83 F;  1SMY E;  2A6E E;  3HKZ K;  4G7H E;  3GTQ F;  3S14 F;  3S2D F;  3PO3 F;  1YNN K;  4OIP E;  2E2H F;  5D4C E;  4Q4Z E;  5IYB F;  4LLG E;  1YNJ K;  2PPB E;  2YU9 F;  2O5I E;  1TWG F;  5C4J F;  4BXX F;  2WAQ K;  3PO2 F;  2O5J E;  4A3C F;  3M3Y F;  1TWA F;  4A3B F;  3GTM F;  3S1Q F;  3HOW F;  1TWF F;  2JA7 F;  3RZD F;  5M3F F;  3I4N F;  2R92 F;  4LK0 E;  4A3J F;  4A93 F;  4YFN E;  4A3G F;  3S1N F;  4MEY E;  2R93 F;  3K7A F;  4A3M F;  4YFX E;  1WCM F;  4BY1 F;  3HOZ F;  1ZYR E;  4C3H F;  4XLN E;  3S17 F;  4JK1 E;  3GTK F;  4A3D F;  2VUM F;  1TWC F;  5IYD F;  2A69 E;  4A3I F;  4C3I F;  2E2J F;  1I50 F;  3I4M F;  2B63 F;  1SFO F;  5FJ8 F;  5FLM F;  5C3E F;  3DXJ E;  4G7O E;  5M5W F;  3HOY F;  2NVY F;  2E2I F;  3GTJ F;  5TMF E;  5D4D E;  3RZO F;  2JA6 F;  4OIO E;  4MEX E;  4KN4 E;  4G7Z E;  5IYC F;  5D4E E;  1R9T F;  2A6H E;  4A3K F;  2JA8 F;  3GTO F;  2CW0 E;  4XLP E;  5C4X F;  1I6V E;  5TMC E;  2PMZ K;  4A3F F;  2NVQ F;  3GTL F;  2R7Z F;  3H0G F;  2Y0S I;  4AYB K;  5BYH E;  1Y1W F;  3S1R F;  4OIN E;  4A3L F;  3S15 F;  3EQL E;  5IP9 F;  4Y7N F;  4OIR E;  4XSX E;  3GTG F;  4GZY E;  4LK1 E;  4YFK E;  4XSZ E;  4Y52 F;  4BBR F;  3GTP F;  4KMU E;  2BE5 E;  5IP7 F;  4LJZ E;  5IPL E;  5E18 E;  2A68 E;  3HOU F;  4X6A F;  1HQM E;  4C3J F;  1I3Q F;  3S1M F;  4BBS F;  3M4O F;  4BY7 F;  1QKL A;  4MQ9 E; 
#chains in the Genus database with same CATH topology
 2JA7 E;  3RZD E;  1Y1V F;  4KN7 E;  1I6H F;  2WB1 I;  5M3F E;  2NVX F;  2JA5 F;  4YG2 E;  4ZH4 E;  3WOD E;  5M3M F;  5M5X F;  5C44 F;  3H3V F;  3I4N E;  2R92 E;  4A3J E;  4C2M F;  4OIQ E;  3H3V G;  4A93 E;  1TWH F;  3S1N E;  4A3G E;  3S2H F;  1TWF E;  5E17 E;  2WAQ H;  2R93 E;  3K7A E;  4A3E F;  4A3M E;  3FKI F;  1WCM E;  2NVT F;  4BY1 E;  1IW7 E;  3S16 F;  3HOZ E;  4C3H E;  3S17 E;  3CQZ F;  3GTK E;  3HOV F;  4A3D E;  3HOX F;  2VUM E;  1TWC E;  5IYD E;  4Q5S E;  5M5Y F;  4A3I E;  1K83 F;  4C3I E;  1SMY E;  2A6E E;  3HKZ K;  4G7H E;  2E2J E;  3GTQ F;  3S14 F;  3S2D F;  1I50 E;  3PO3 F;  1YNN K;  4OIP E;  3I4M E;  2E2H F;  2NVX E;  2B63 E;  5D4C E;  4Q4Z E;  5IYB F;  4LLG E;  1YNJ K;  5FJ8 E;  5FLM E;  5C3E E;  1SFO E;  2PPB E;  1TWG F;  5M5W E;  5C4J F;  2O5I E;  3HOY E;  2WAQ K;  2NVY E;  4BXX F;  3PO2 F;  2E2I E;  2O5J E;  3HKZ H;  4A3C F;  3M3Y F;  1TWA F;  4A3B F;  3GTM F;  3GTJ E;  3S1Q F;  3HOW F;  1TWF F;  2JA6 E;  3RZO E;  2JA7 F;  3RZD F;  5M3F F;  5IYC E;  1R9T E;  3I4N F;  4A3K E;  2R92 F;  4LK0 E;  3GTO E;  2KRX A;  4A3J F;  5C4X E;  4A3F E;  3GTL E;  2NVQ E;  4YFN E;  2R7Z E;  3S1N F;  3H0G E;  4A93 F;  4A3G F;  4MEY E;  2Y0S H;  2R93 F;  3K7A F;  4A3M F;  4YFX E;  1WCM F;  1Y1W E;  4BY1 F;  3S1R E;  3HOZ F;  4C3H F;  4XLN E;  3S17 F;  4JK1 E;  3GTK F;  4A3L E;  3S15 E;  4A3D F;  2VUM F;  1TWC F;  5IYD F;  2A69 E;  4A3I F;  4C3I F;  2E2J F;  5IP9 E;  4Y7N E;  1I50 F;  3GTG E;  3I4M F;  2B63 F;  3GTP E;  4BBR E;  4Y52 E;  1SFO F;  2PMZ H;  5FJ8 F;  5FLM F;  5C3E F;  3DXJ E;  5IP7 E;  5M5W F;  4G7O E;  3HOY F;  2NVY F;  2E2I F;  3HOU E;  4X6A E;  4C3J E;  4QIW H;  1I3Q E;  3S1M E;  3GTJ F;  3M4O E;  5TMF E;  4BBS E;  5D4D E;  3RZO F;  2JA6 F;  4BY7 E;  4A3E E;  2JA8 E;  4OIO E;  1I6H E;  1Y1V E;  1DZF A;  4MEX E;  2WB1 H;  4KN4 E;  4G7Z E;  5IYC F;  5D4E E;  1R9T F;  2A6H E;  4A3K F;  5M5X E;  5C44 E;  2JA5 E;  5M3M E;  2JA8 F;  3GTO F;  2CW0 E;  4XLP E;  5C4X F;  1I6V E;  5TMC E;  2PMZ K;  4C2M E;  4A3F F;  2NVQ F;  3GTL F;  2R7Z F;  3H0G F;  1TWH E;  3S2H E;  2Y0S I;  3FKI E;  4AYB K;  5BYH E;  1Y1W F;  2NVT E;  3S1R F;  4QIW K;  3S16 E;  4OIN E;  3CQZ E;  4BY7 F;  3HOV E;  3S15 F;  4A3L F;  3HOX E;  5M5Y E;  1K83 E;  3EQL E;  5IP9 F;  3GTQ E;  3S14 E;  4Y7N F;  4OIR E;  3S2D E;  4XSX E;  3GTG F;  4GZY E;  3PO3 E;  4AYB H;  4LK1 E;  4YFK E;  4XSZ E;  2E2H E;  4Y52 F;  4BBR F;  3GTP F;  4KMU E;  2YU9 F;  5IYB E;  2YU9 E;  2BE5 E;  1EIK A;  5IP7 F;  4LJZ E;  1TWG E;  5C4J E;  5E18 E;  4BXX E;  5IPL E;  2A68 E;  3PO2 E;  4A3C E;  3HOU F;  3M3Y E;  1TWA E;  4A3B E;  4X6A F;  1HQM E;  4C3J F;  1I3Q F;  3S1M F;  4BBS F;  3GTM E;  3M4O F;  3S1Q E;  3HOW E;  1ZYR E;  1QKL A;  4MQ9 E; 
#chains in the Genus database with same CATH homology
 1I6H F;  1Y1V F;  4KN7 E;  2WB1 I;  2NVX F;  2JA5 F;  4YG2 E;  4ZH4 E;  3WOD E;  5M3M F;  5M5X F;  5C44 F;  4C2M F;  4OIQ E;  3H3V G;  1TWH F;  3S2H F;  5E17 E;  4A3E F;  3FKI F;  2NVT F;  1IW7 E;  3S16 F;  3CQZ F;  3HOV F;  3HOX F;  5M5Y F;  4Q5S E;  1K83 F;  1SMY E;  2A6E E;  3HKZ K;  4G7H E;  3GTQ F;  3S14 F;  3S2D F;  3PO3 F;  1YNN K;  4OIP E;  2E2H F;  5D4C E;  4Q4Z E;  5IYB F;  4LLG E;  1YNJ K;  2PPB E;  2YU9 F;  2O5I E;  1TWG F;  5C4J F;  4BXX F;  2WAQ K;  3PO2 F;  2O5J E;  4A3C F;  3M3Y F;  1TWA F;  4A3B F;  3GTM F;  3S1Q F;  3HOW F;  1TWF F;  2JA7 F;  3RZD F;  5M3F F;  3I4N F;  2R92 F;  4LK0 E;  2KRX A;  4A3J F;  4A93 F;  4YFN E;  4A3G F;  3S1N F;  4MEY E;  2R93 F;  3K7A F;  4A3M F;  4YFX E;  1WCM F;  4BY1 F;  3HOZ F;  1ZYR E;  4C3H F;  4XLN E;  3S17 F;  4JK1 E;  3GTK F;  4A3D F;  2VUM F;  1TWC F;  5IYD F;  2A69 E;  4A3I F;  4C3I F;  2E2J F;  1I50 F;  3I4M F;  2B63 F;  1SFO F;  5FJ8 F;  5FLM F;  5C3E F;  3DXJ E;  4G7O E;  5M5W F;  3HOY F;  2NVY F;  2E2I F;  3GTJ F;  5TMF E;  5D4D E;  3RZO F;  2JA6 F;  4OIO E;  4MEX E;  4KN4 E;  4G7Z E;  5IYC F;  5D4E E;  1R9T F;  2A6H E;  4A3K F;  2JA8 F;  3GTO F;  2CW0 E;  4XLP E;  5C4X F;  1I6V E;  5TMC E;  2PMZ K;  4A3F F;  2NVQ F;  3GTL F;  2R7Z F;  3H0G F;  2Y0S I;  4AYB K;  5BYH E;  1Y1W F;  3S1R F;  4QIW K;  4OIN E;  4A3L F;  3S15 F;  3EQL E;  5IP9 F;  4Y7N F;  4OIR E;  4XSX E;  3GTG F;  4GZY E;  4LK1 E;  4YFK E;  4XSZ E;  4Y52 F;  4BBR F;  3GTP F;  4KMU E;  2BE5 E;  5IP7 F;  4LJZ E;  5IPL E;  5E18 E;  2A68 E;  3HOU F;  4X6A F;  1HQM E;  4C3J F;  1I3Q F;  3S1M F;  4BBS F;  3M4O F;  4BY7 F;  1QKL A;  4MQ9 E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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