5E17E

T. thermophilus transcription initiation complex having a rrr discriminator sequence and a nontemplate-strand length corresponding to tss selection at position 7 (rpo-ggg-7)
Total Genus 24
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
24
sequence length
94
structure length
94
Chain Sequence
AEPGIDKLFGMVDSKYRLTVVVAKRAQQLLRHGFKNTVLEPEERPKMQTLEGLFDDPNAVTWAMKELLTGRLVFGENLVPEDRLQKEMERLYPV
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Multiplexed protein-DNA cross-linking: Scrunching in transcription start site selection.
pubmed doi rcsb
molecule tags Transcription/dna/rna
source organism Thermus thermophilus (strain hb8 / atcc 27634 / dsm 579)
molecule keywords DNA-directed RNA polymerase subunit alpha
total genus 24
structure length 94
sequence length 94
ec nomenclature ec 2.7.7.6: DNA-directed RNA polymerase.
pdb deposition date 2015-09-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF01192 RNA_pol_Rpb6 RNA polymerase Rpb6
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.940.10 Alpha Beta Alpha-Beta Complex Eukaryotic RPB6 RNA polymerase subunit Eukaryotic RPB6 RNA polymerase subunit 5e17E00
3GTGF 2R92F 4X6AF 1WCMF 4C3IF 4A93F 1ZYRE 3H0GF 5M3MF 5IYBF 4KN4E 4OIQE 4A3BF 2VUMF 1IW7E 4YFNE 4YFKE 5E17E 4MEXE 3S1MF 5E18E 4XLNE 5C44F 1HQME 2NVQF 4MQ9E 4OINE 1SMYE 1TWFF 3GTOF 5M3FF 3WODE 3M3YF 5IP7F 4A3KF 4BY1F 2B63F 2NVTF 5M5XF 4LLGE 1YNNK 3GTMF 1Y1VF 2WB1I 3DXJE 4GZYE 5FJ8F 4KN7E 4A3IF 3I4NF 4Y7NF 4YG2E 2E2JF 5C4XF 4A3EF 4BBSF 3GTPF 2JA5F 4LK0E 4JK1E 3HOYF 2JA8F 4BBRF 3S15F 2Y0SI 5FLMF 1Y1WF 5TMCE 3CQZF 4AYBK 4A3DF 2R93F 2NVYF 4A3LF 3S16F 2PMZK 5IYDF 4A3GF 4LK1E 5IPLE 3S14F 3GTJF 5C4JF 4A3FF 4MEYE 3S1QF 4XSXE 5IP9F 4ZH4E 4OIRE 2CW0E 3GTKF 3S17F 2A6EE 4XSZE 1TWAF 4BY7F 3FKIF 2WAQK 3H3VG 5M5YF 3S2HF 3M4OF 2O5JE 3K7AF 4YFXE 1K83F 3S1NF 2E2HF 3RZDF 2PPBE 1I6VE 2A68E 2A6HE 4XLPE 1SFOF 4C3JF 5TMFE 3HOUF 1TWCF 4KMUE 3HOZF 3GTLF 4OIPE 3I4MF 5D4EE 1QKLA 4G7ZE 5D4DE 2E2IF 3PO3F 5M5WF 4LJZE 3HOVF 3RZOF 4Q4ZE 1R9TF 2YU9F 1TWGF 3S2DF 2O5IE 3EQLE 2R7ZF 1I3QF 2BE5E 2A69E 1TWHF 4C2MF 3S1RF 3PO2F 1I6HF 5D4CE 4A3CF 2NVXF 5IYCF 5C3EF 4G7HE 4BXXF 3HOWF 1YNJK 4A3JF 4OIOE 4A3MF 4Y52F 3HKZK 4C3HF 4G7OE 3GTQF 2JA6F 3HOXF 2JA7F 4Q5SE 5BYHE 1I50F
chains in the Genus database with same CATH superfamily
3GTGF 2R92F 4X6AF 1WCMF 4C3IF 4A93F 1ZYRE 3H0GF 5M3MF 5IYBF 4KN4E 4OIQE 4A3BF 3S1RE 3PO2E 2VUMF 1IW7E 4YFNE 1I6HE 4YFKE 4A3CE 4MEXE 3S1MF 2NVXE 5E18E 5IYCE 5C3EE 4BXXE 4XLNE 5C44F 1HQME 2NVQF 4MQ9E 4OINE 3HOWE 1SMYE 1TWFF 3GTOF 4A3JE 1EIKA 5M3FF 4A3ME 3WODE 3M3YF 4Y52E 5IP7F 4A3KF 4BY1F 2B63F 5M5WE 2NVTF 4C3HE 5M5XF 3GTQE 4LLGE 1YNNK 3HOXE 2JA6E 2JA7E 3GTMF 1Y1VF 2WB1I 1I50E 4X6AE 1WCME 3DXJE 4C3IE 5FJ8F 3H0GE 4KN7E 5M3ME 5IYBE 4A3IF 3I4NF 4A93E 4GZYE 1I3QE 4Y7NF 4YG2E 4QIWH 4A3BE 2E2JF 5C4XF 2VUME 1TWHE 4A3EF 4C2ME 3S1ME 4BBSF 3GTPF 5C44E 2JA5F 2NVQE 4LK0E 4JK1E 3HOYF 2WB1H 2JA8F 4BBRF 3S15F 1TWFE 2Y0SI 5FLMF 1Y1WF 5TMCE 3CQZF 5M3FE 4AYBK 3HKZH 4A3DF 2R93F 5IP7E 2NVYF 4A3KE 4A3LF 4BY1E 2B63E 3S16F 2PMZK 5IYDF 2NVTE 4LK1E 4A3GF 5M5XE 3H3VF 3S14F 5IPLE 3GTJF 3GTME 5C4JF 4A3FF 4MEYE 1Y1VE 3S1QF 4XSXE 4A3IE 5IP9F 4ZH4E 4OIRE 2CW0E 3GTKF 3S17F 2A6EE 4Y7NE 4XSZE 1TWAF 4BY7F 3FKIF 2WAQK 2E2JE 3GTGE 2R92E 5C4XE 3H3VG 5M5YF 4A3EE 3S2HF 4BBSE 3M4OF 2O5JE 2JA5E 3K7AF 3HOYE 2JA8E 4YFXE 3S15E 1K83F 3S1NF 2E2HF 5FLME 1Y1WE 3RZDF 2PPBE 1I6VE 4A3DE 2R93E 2A68E 4A3LE 2A6HE 4XLPE 3S16E 1SFOF 5IYDE 3GTOE 4C3JF 5TMFE 4A3GE 3HOUF 1TWCF 3GTJE 3M3YE 5C4JE 4KMUE 4A3FE 3HOZF 3GTLF 4OIPE 3I4MF 5D4EE 1QKLA 4G7ZE 5D4DE 2E2IF 3PO3F 5M5WF 5IP9E 4LJZE 3S17E 3HOVF 3RZOF 4Q4ZE 1TWAE 4BY7E 3FKIE 1R9TF 2Y0SH 2YU9F 5FJ8E 5M5YE 3S2HE 3I4NE 3M4OE 1TWGF 3K7AE 3S2DF 1DZFA 2O5IE 3EQLE 1K83E 2R7ZF 3S1NE 1I3QF 2E2HE 2BE5E 4AYBH 3RZDE 3GTPE 2A69E 1TWHF 2PMZH 4BBRE 4C2MF 1SFOE 4C3JE 3HOUE 1TWCE 3CQZE 3S1RF 4QIWK 3PO2F 1I6HF 3HOZE 2NVYE 5D4CE 3GTLE 4A3CF 3I4ME 2NVXF 5IYCF 5C3EF 4G7HE 3S14E 4BXXF 3HOWF 2E2IE 1YNJK 2KRXA 3PO3E 4A3JF 3HOVE 4OIOE 3RZOE 4A3MF 4Y52F 2WAQH 3HKZK 5E17E 3S1QE 1R9TE 2YU9E 4C3HF 3GTKE 4G7OE 3GTQF 2JA6F 3HOXF 2JA7F 4Q5SE 1TWGE 3S2DE 5BYHE 2R7ZE 1I50F
chains in the Genus database with same CATH topology
3GTGF 2R92F 4X6AF 1WCMF 4C3IF 4A93F 1ZYRE 3H0GF 5M3MF 5IYBF 4KN4E 4OIQE 4A3BF 2VUMF 1IW7E 4YFNE 4YFKE 5E17E 4MEXE 3S1MF 5E18E 4XLNE 5C44F 1HQME 2NVQF 4MQ9E 4OINE 1SMYE 1TWFF 3GTOF 5M3FF 3WODE 3M3YF 5IP7F 4A3KF 4BY1F 2B63F 2NVTF 5M5XF 4LLGE 1YNNK 3GTMF 1Y1VF 2WB1I 3DXJE 4GZYE 5FJ8F 4KN7E 4A3IF 3I4NF 4Y7NF 4YG2E 2E2JF 5C4XF 4A3EF 4BBSF 3GTPF 2JA5F 4LK0E 4JK1E 3HOYF 2JA8F 4BBRF 3S15F 2Y0SI 5FLMF 1Y1WF 5TMCE 3CQZF 4AYBK 4A3DF 2R93F 2NVYF 4A3LF 3S16F 2PMZK 5IYDF 4A3GF 4LK1E 5IPLE 3S14F 3GTJF 5C4JF 4A3FF 4MEYE 3S1QF 4XSXE 5IP9F 4ZH4E 4OIRE 2CW0E 3GTKF 3S17F 2A6EE 4XSZE 1TWAF 4BY7F 3FKIF 2WAQK 3H3VG 5M5YF 3S2HF 3M4OF 2O5JE 3K7AF 4YFXE 1K83F 3S1NF 2E2HF 3RZDF 2PPBE 1I6VE 2A68E 2A6HE 4XLPE 1SFOF 4C3JF 5TMFE 3HOUF 1TWCF 4KMUE 3HOZF 3GTLF 4OIPE 3I4MF 5D4EE 1QKLA 4G7ZE 5D4DE 2E2IF 3PO3F 5M5WF 4LJZE 3HOVF 3RZOF 4Q4ZE 1R9TF 2YU9F 1TWGF 3S2DF 2O5IE 3EQLE 2R7ZF 1I3QF 2BE5E 2A69E 1TWHF 4C2MF 3S1RF 4QIWK 3PO2F 1I6HF 5D4CE 4A3CF 2NVXF 5IYCF 5C3EF 4G7HE 4BXXF 3HOWF 1YNJK 2KRXA 4A3JF 4OIOE 4A3MF 4Y52F 3HKZK 4C3HF 4G7OE 3GTQF 2JA6F 3HOXF 2JA7F 4Q5SE 5BYHE 1I50F
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3GTG F;  2R92 F;  4X6A F;  1WCM F;  4C3I F;  4A93 F;  1ZYR E;  3H0G F;  5M3M F;  5IYB F;  4KN4 E;  4OIQ E;  4A3B F;  2VUM F;  1IW7 E;  4YFN E;  4YFK E;  5E17 E;  4MEX E;  3S1M F;  5E18 E;  4XLN E;  5C44 F;  1HQM E;  2NVQ F;  4MQ9 E;  4OIN E;  1SMY E;  1TWF F;  3GTO F;  5M3F F;  3WOD E;  3M3Y F;  5IP7 F;  4A3K F;  4BY1 F;  2B63 F;  2NVT F;  5M5X F;  4LLG E;  1YNN K;  3GTM F;  1Y1V F;  2WB1 I;  3DXJ E;  4GZY E;  5FJ8 F;  4KN7 E;  4A3I F;  3I4N F;  4Y7N F;  4YG2 E;  2E2J F;  5C4X F;  4A3E F;  4BBS F;  3GTP F;  2JA5 F;  4LK0 E;  4JK1 E;  3HOY F;  2JA8 F;  4BBR F;  3S15 F;  2Y0S I;  5FLM F;  1Y1W F;  5TMC E;  3CQZ F;  4AYB K;  4A3D F;  2R93 F;  2NVY F;  4A3L F;  3S16 F;  2PMZ K;  5IYD F;  4A3G F;  4LK1 E;  5IPL E;  3S14 F;  3GTJ F;  5C4J F;  4A3F F;  4MEY E;  3S1Q F;  4XSX E;  5IP9 F;  4ZH4 E;  4OIR E;  2CW0 E;  3GTK F;  3S17 F;  2A6E E;  4XSZ E;  1TWA F;  4BY7 F;  3FKI F;  2WAQ K;  3H3V G;  5M5Y F;  3S2H F;  3M4O F;  2O5J E;  3K7A F;  4YFX E;  1K83 F;  3S1N F;  2E2H F;  3RZD F;  2PPB E;  1I6V E;  2A68 E;  2A6H E;  4XLP E;  1SFO F;  4C3J F;  5TMF E;  3HOU F;  1TWC F;  4KMU E;  3HOZ F;  3GTL F;  4OIP E;  3I4M F;  5D4E E;  1QKL A;  4G7Z E;  5D4D E;  2E2I F;  3PO3 F;  5M5W F;  4LJZ E;  3HOV F;  3RZO F;  4Q4Z E;  1R9T F;  2YU9 F;  1TWG F;  3S2D F;  2O5I E;  3EQL E;  2R7Z F;  1I3Q F;  2BE5 E;  2A69 E;  1TWH F;  4C2M F;  3S1R F;  3PO2 F;  1I6H F;  5D4C E;  4A3C F;  2NVX F;  5IYC F;  5C3E F;  4G7H E;  4BXX F;  3HOW F;  1YNJ K;  4A3J F;  4OIO E;  4A3M F;  4Y52 F;  3HKZ K;  4C3H F;  4G7O E;  3GTQ F;  2JA6 F;  3HOX F;  2JA7 F;  4Q5S E;  5BYH E;  1I50 F; 
#chains in the Genus database with same CATH topology
 3GTG F;  2R92 F;  4X6A F;  1WCM F;  4C3I F;  4A93 F;  1ZYR E;  3H0G F;  5M3M F;  5IYB F;  4KN4 E;  4OIQ E;  4A3B F;  3S1R E;  3PO2 E;  2VUM F;  1IW7 E;  4YFN E;  1I6H E;  4YFK E;  4A3C E;  4MEX E;  3S1M F;  2NVX E;  5E18 E;  5IYC E;  5C3E E;  4BXX E;  4XLN E;  5C44 F;  1HQM E;  2NVQ F;  4MQ9 E;  4OIN E;  3HOW E;  1SMY E;  1TWF F;  3GTO F;  4A3J E;  1EIK A;  5M3F F;  4A3M E;  3WOD E;  3M3Y F;  4Y52 E;  5IP7 F;  4A3K F;  4BY1 F;  2B63 F;  5M5W E;  2NVT F;  4C3H E;  5M5X F;  3GTQ E;  4LLG E;  1YNN K;  3HOX E;  2JA6 E;  2JA7 E;  3GTM F;  1Y1V F;  2WB1 I;  1I50 E;  4X6A E;  1WCM E;  3DXJ E;  4C3I E;  5FJ8 F;  3H0G E;  4KN7 E;  5M3M E;  5IYB E;  4A3I F;  3I4N F;  4A93 E;  4GZY E;  1I3Q E;  4Y7N F;  4YG2 E;  4QIW H;  4A3B E;  2E2J F;  5C4X F;  2VUM E;  1TWH E;  4A3E F;  4C2M E;  3S1M E;  4BBS F;  3GTP F;  5C44 E;  2JA5 F;  2NVQ E;  4LK0 E;  4JK1 E;  3HOY F;  2WB1 H;  2JA8 F;  4BBR F;  3S15 F;  1TWF E;  2Y0S I;  5FLM F;  1Y1W F;  5TMC E;  3CQZ F;  5M3F E;  4AYB K;  3HKZ H;  4A3D F;  2R93 F;  5IP7 E;  2NVY F;  4A3K E;  4A3L F;  4BY1 E;  2B63 E;  3S16 F;  2PMZ K;  5IYD F;  2NVT E;  4LK1 E;  4A3G F;  5M5X E;  3H3V F;  3S14 F;  5IPL E;  3GTJ F;  3GTM E;  5C4J F;  4A3F F;  4MEY E;  1Y1V E;  3S1Q F;  4XSX E;  4A3I E;  5IP9 F;  4ZH4 E;  4OIR E;  2CW0 E;  3GTK F;  3S17 F;  2A6E E;  4Y7N E;  4XSZ E;  1TWA F;  4BY7 F;  3FKI F;  2WAQ K;  2E2J E;  3GTG E;  2R92 E;  5C4X E;  3H3V G;  5M5Y F;  4A3E E;  3S2H F;  4BBS E;  3M4O F;  2O5J E;  2JA5 E;  3K7A F;  3HOY E;  2JA8 E;  4YFX E;  3S15 E;  1K83 F;  3S1N F;  2E2H F;  5FLM E;  1Y1W E;  3RZD F;  2PPB E;  1I6V E;  4A3D E;  2R93 E;  2A68 E;  4A3L E;  2A6H E;  4XLP E;  3S16 E;  1SFO F;  5IYD E;  3GTO E;  4C3J F;  5TMF E;  4A3G E;  3HOU F;  1TWC F;  3GTJ E;  3M3Y E;  5C4J E;  4KMU E;  4A3F E;  3HOZ F;  3GTL F;  4OIP E;  3I4M F;  5D4E E;  1QKL A;  4G7Z E;  5D4D E;  2E2I F;  3PO3 F;  5M5W F;  5IP9 E;  4LJZ E;  3S17 E;  3HOV F;  3RZO F;  4Q4Z E;  1TWA E;  4BY7 E;  3FKI E;  1R9T F;  2Y0S H;  2YU9 F;  5FJ8 E;  5M5Y E;  3S2H E;  3I4N E;  3M4O E;  1TWG F;  3K7A E;  3S2D F;  1DZF A;  2O5I E;  3EQL E;  1K83 E;  2R7Z F;  3S1N E;  1I3Q F;  2E2H E;  2BE5 E;  4AYB H;  3RZD E;  3GTP E;  2A69 E;  1TWH F;  2PMZ H;  4BBR E;  4C2M F;  1SFO E;  4C3J E;  3HOU E;  1TWC E;  3CQZ E;  3S1R F;  4QIW K;  3PO2 F;  1I6H F;  3HOZ E;  2NVY E;  5D4C E;  3GTL E;  4A3C F;  3I4M E;  2NVX F;  5IYC F;  5C3E F;  4G7H E;  3S14 E;  4BXX F;  3HOW F;  2E2I E;  1YNJ K;  2KRX A;  3PO3 E;  4A3J F;  3HOV E;  4OIO E;  3RZO E;  4A3M F;  4Y52 F;  2WAQ H;  3HKZ K;  5E17 E;  3S1Q E;  1R9T E;  2YU9 E;  4C3H F;  3GTK E;  4G7O E;  3GTQ F;  2JA6 F;  3HOX F;  2JA7 F;  4Q5S E;  1TWG E;  3S2D E;  5BYH E;  2R7Z E;  1I50 F; 
#chains in the Genus database with same CATH homology
 3GTG F;  2R92 F;  4X6A F;  1WCM F;  4C3I F;  4A93 F;  1ZYR E;  3H0G F;  5M3M F;  5IYB F;  4KN4 E;  4OIQ E;  4A3B F;  2VUM F;  1IW7 E;  4YFN E;  4YFK E;  5E17 E;  4MEX E;  3S1M F;  5E18 E;  4XLN E;  5C44 F;  1HQM E;  2NVQ F;  4MQ9 E;  4OIN E;  1SMY E;  1TWF F;  3GTO F;  5M3F F;  3WOD E;  3M3Y F;  5IP7 F;  4A3K F;  4BY1 F;  2B63 F;  2NVT F;  5M5X F;  4LLG E;  1YNN K;  3GTM F;  1Y1V F;  2WB1 I;  3DXJ E;  4GZY E;  5FJ8 F;  4KN7 E;  4A3I F;  3I4N F;  4Y7N F;  4YG2 E;  2E2J F;  5C4X F;  4A3E F;  4BBS F;  3GTP F;  2JA5 F;  4LK0 E;  4JK1 E;  3HOY F;  2JA8 F;  4BBR F;  3S15 F;  2Y0S I;  5FLM F;  1Y1W F;  5TMC E;  3CQZ F;  4AYB K;  4A3D F;  2R93 F;  2NVY F;  4A3L F;  3S16 F;  2PMZ K;  5IYD F;  4A3G F;  4LK1 E;  5IPL E;  3S14 F;  3GTJ F;  5C4J F;  4A3F F;  4MEY E;  3S1Q F;  4XSX E;  5IP9 F;  4ZH4 E;  4OIR E;  2CW0 E;  3GTK F;  3S17 F;  2A6E E;  4XSZ E;  1TWA F;  4BY7 F;  3FKI F;  2WAQ K;  3H3V G;  5M5Y F;  3S2H F;  3M4O F;  2O5J E;  3K7A F;  4YFX E;  1K83 F;  3S1N F;  2E2H F;  3RZD F;  2PPB E;  1I6V E;  2A68 E;  2A6H E;  4XLP E;  1SFO F;  4C3J F;  5TMF E;  3HOU F;  1TWC F;  4KMU E;  3HOZ F;  3GTL F;  4OIP E;  3I4M F;  5D4E E;  1QKL A;  4G7Z E;  5D4D E;  2E2I F;  3PO3 F;  5M5W F;  4LJZ E;  3HOV F;  3RZO F;  4Q4Z E;  1R9T F;  2YU9 F;  1TWG F;  3S2D F;  2O5I E;  3EQL E;  2R7Z F;  1I3Q F;  2BE5 E;  2A69 E;  1TWH F;  4C2M F;  3S1R F;  4QIW K;  3PO2 F;  1I6H F;  5D4C E;  4A3C F;  2NVX F;  5IYC F;  5C3E F;  4G7H E;  4BXX F;  3HOW F;  1YNJ K;  2KRX A;  4A3J F;  4OIO E;  4A3M F;  4Y52 F;  3HKZ K;  4C3H F;  4G7O E;  3GTQ F;  2JA6 F;  3HOX F;  2JA7 F;  4Q5S E;  5BYH E;  1I50 F; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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