5E18E

T. thermophilus transcription initiation complex having a yyy discriminator sequence and a nontemplate-strand length corresponding to tss selection at position 8 (rpo-ccc-8)
Total Genus 24
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
24
sequence length
94
structure length
94
Chain Sequence
AEPGIDKLFGMVDSKYRLTVVVAKRAQQLLRHGFKNTVLEPEERPKMQTLEGLFDDPNAVTWAMKELLTGRLVFGENLVPEDRLQKEMERLYPV
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Multiplexed protein-DNA cross-linking: Scrunching in transcription start site selection.
pubmed doi rcsb
molecule tags Transcription/dna/rna
source organism Thermus thermophilus (strain hb8 / atcc 27634 / dsm 579)
molecule keywords DNA-directed RNA polymerase subunit alpha
total genus 24
structure length 94
sequence length 94
ec nomenclature ec 2.7.7.6: DNA-directed RNA polymerase.
pdb deposition date 2015-09-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF01192 RNA_pol_Rpb6 RNA polymerase Rpb6
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.940.10 Alpha Beta Alpha-Beta Complex Eukaryotic RPB6 RNA polymerase subunit Eukaryotic RPB6 RNA polymerase subunit 5e18E00
5E18E 3HOXF 4AYBK 4KMUE 2O5IE 3S1QF 4KN7E 4Y7NF 5TMCE 2R92F 3HOYF 3HKZK 2E2IF 3GTJF 4A93F 4KN4E 2Y0SI 2A6EE 2JA6F 2NVQF 1TWGF 3S17F 3H0GF 4A3BF 3S1MF 1TWFF 2PMZK 3DXJE 4MQ9E 4YFXE 4C3HF 1YNNK 3I4MF 4C2MF 2R7ZF 2A68E 4OIOE 5BYHE 3RZOF 4GZYE 3S16F 1TWAF 4G7OE 4JK1E 1HQME 4LK1E 3S15F 4LLGE 4BBRF 1Y1VF 4Y52F 2O5JE 2NVTF 2JA8F 5M3FF 5D4EE 5C44F 4Q5SE 5IYCF 2E2HF 3FKIF 3GTOF 3GTKF 4A3JF 1SFOF 3EQLE 5FJ8F 4A3CF 4A3LF 3S1NF 3H3VG 3M3YF 1YNJK 4LK0E 3WODE 5M5XF 5C3EF 5E17E 2BE5E 2JA7F 4BY7F 3PO2F 5FLMF 4YFKE 4A3KF 3S14F 4OIQE 1I3QF 2WB1I 4A3FF 3HOZF 4YFNE 2VUMF 2NVXF 4YG2E 2CW0E 2WAQK 4X6AF 3GTLF 4A3DF 3RZDF 3I4NF 4G7HE 4A3MF 4G7ZE 5IP9F 1WCMF 2A6HE 3HOVF 2E2JF 1I6HF 5M5YF 4OIPE 3GTGF 3PO3F 2R93F 3M4OF 5IPLE 4XLPE 4XSZE 4Q4ZE 4BBSF 5C4JF 4OIRE 4XSXE 4A3GF 4ZH4E 3S2DF 4A3EF 1TWCF 5IYDF 1R9TF 3CQZF 3K7AF 2PPBE 2NVYF 5D4DE 5IP7F 1Y1WF 4BXXF 3S1RF 1ZYRE 2YU9F 2B63F 4MEYE 3HOUF 1I6VE 5D4CE 1TWHF 5IYBF 1SMYE 4XLNE 4OINE 5C4XF 4C3IF 1IW7E 3GTQF 5TMFE 1K83F 1I50F 5M5WF 2A69E 4A3IF 4MEXE 3GTPF 3GTMF 3HOWF 1QKLA 4BY1F 3S2HF 4C3JF 2JA5F 5M3MF 4LJZE
chains in the Genus database with same CATH superfamily
3GTJE 5E18E 3HOXF 4AYBK 2NVQE 5M3MF 1DZFA 2JA6E 2O5IE 3S1QF 4A93E 3H0GE 4A3BE 1TWFE 4KN7E 4Y7NF 5TMCE 2R92F 3HOYF 3HKZK 2E2IF 4C3HE 3I4ME 2Y0SH 3GTQE 3GTJF 2R7ZE 4KN4E 2Y0SI 2A6EE 2JA6F 1I50E 1TWGF 2NVQF 3RZOE 3S17F 3H0GF 4A3BF 3S1MF 1TWFF 3S16E 1TWAE 2PMZK 3GTPE 3GTME 3HOWE 3DXJE 4MQ9E 4YFXE 4C3HF 1EIKA 1YNNK 4QIWK 2JA5E 3I4MF 4C2MF 5M3ME 2R7ZF 3HOXE 2A68E 4OIOE 5BYHE 3RZOF 1Y1VE 4GZYE 2NVTE 3S16F 2JA8E 1TWAF 5M3FE 5C44E 4G7OE 4JK1E 2R92E 1HQME 4LK1E 3S15F 4LLGE 2E2HE 3H3VF 4AYBH 3FKIE 4BBRF 3GTOE 4A3JE 1TWGE 1Y1VF 4Y52F 3S17E 1SFOE 2NVTF 2O5JE 3S1ME 2JA8F 5FJ8E 5M3FF 4A3CE 5D4EE 5C44F 4A3LE 3S1NE 3M3YE 4Q5SE 5IYCF 5M5XE 5C3EE 2E2HF 4C2ME 3FKIF 3GTOF 2JA7E 4A3JF 3GTKF 3PO2E 5FLME 1SFOF 3EQLE 4A3KE 3S14E 5FJ8F 4A3CF 4A3LF 1I3QE 3S1NF 4A3FE 3H3VG 4QIWH 3M3YF 3S15E 1YNJK 3HOZE 4LK0E 3WODE 5M5XF 5C3EF 3HOUE 5E17E 2BE5E 4BBRE 2JA7F 4BY7F 3PO2F 5FLMF 4Y52E 4YFKE 4A3KF 2WB1H 3S14F 4X6AE 4OIQE 1I3QF 2WB1I 3GTLE 3RZDE 4A3FF 3I4NE 3HOZF 5IP9E 5IYCE 1WCME 4YFNE 2VUMF 2NVXF 4YG2E 2CW0E 3GTKE 2WAQK 3HOVE 2E2JE 1I6HE 5M5YE 4X6AF 2KRXA 3HKZH 3GTLF 4A3DF 3RZDF 3GTGE 3I4NF 4G7HE 3PO3E 4A3MF 4G7ZE 5IP9F 1WCMF 4BBSE 5C4JE 2A6HE 4BY7E 4A3GE 3HOVF 2E2JF 2PMZH 1I6HF 5M5YF 4OIPE 4A3EE 1TWCE 5IYDE 1R9TE 3CQZE 3GTGF 3PO3F 2R93F 3M4OF 3K7AE 4XLPE 5IPLE 2NVYE 4XSZE 2VUME 4Q4ZE 2NVXE 5C4JF 1Y1WE 4BBSF 4BXXE 4OIRE 4XSXE 4A3GF 4ZH4E 2YU9E 2B63E 3S2DF 4A3EF 4A3DE 1TWCF 5IYDF 1R9TF 3CQZF 1TWHE 3K7AF 5IYBE 4A3ME 2PPBE 2NVYF 5D4DE 2WAQH 5IP7F 1Y1WF 4BXXF 3S1RF 1ZYRE 5C4XE 2YU9F 4C3IE 4MEYE 2B63F 3HOUF 1K83E 1I6VE 5M5WE 2R93E 5D4CE 4A3IE 1TWHF 5IYBF 3M4OE 4A93F 4BY1E 1SMYE 4XLNE 3S1RE 3S2HE 4OINE 4C3JE 5C4XF 4C3IF 1IW7E 3GTQF 5TMFE 3S2DE 1K83F 1I50F 3S1QE 5M5WF 2A69E 4A3IF 4MEXE 4Y7NE 3GTPF 3GTMF 3HOYE 3HOWF 1QKLA 4BY1F 5IP7E 2E2IE 3S2HF 4C3JF 2JA5F 4KMUE 4LJZE
chains in the Genus database with same CATH topology
5E18E 3HOXF 4AYBK 4KMUE 2O5IE 3S1QF 4KN7E 4Y7NF 5TMCE 2R92F 3HOYF 3HKZK 2E2IF 3GTJF 4A93F 4KN4E 2Y0SI 2A6EE 2JA6F 2NVQF 1TWGF 3S17F 3H0GF 4A3BF 3S1MF 1TWFF 2PMZK 3DXJE 4MQ9E 4YFXE 4C3HF 1YNNK 4QIWK 3I4MF 4C2MF 2R7ZF 2A68E 4OIOE 5BYHE 3RZOF 4GZYE 3S16F 1TWAF 4G7OE 4JK1E 1HQME 4LK1E 3S15F 4LLGE 4BBRF 1Y1VF 4Y52F 2O5JE 2NVTF 2JA8F 5M3FF 5D4EE 5C44F 4Q5SE 5IYCF 2E2HF 3FKIF 3GTOF 3GTKF 4A3JF 1SFOF 3EQLE 5FJ8F 4A3CF 4A3LF 3S1NF 3H3VG 3M3YF 1YNJK 4LK0E 3WODE 5M5XF 5C3EF 5E17E 2BE5E 2JA7F 4BY7F 3PO2F 5FLMF 4YFKE 4A3KF 3S14F 4OIQE 1I3QF 2WB1I 4A3FF 3HOZF 4YFNE 2VUMF 2NVXF 4YG2E 2CW0E 2WAQK 4X6AF 2KRXA 3GTLF 4A3DF 3RZDF 3I4NF 4G7HE 4A3MF 4G7ZE 5IP9F 1WCMF 2A6HE 3HOVF 2E2JF 1I6HF 5M5YF 4OIPE 3GTGF 3PO3F 2R93F 3M4OF 5IPLE 4XLPE 4XSZE 4Q4ZE 4BBSF 5C4JF 4OIRE 4XSXE 4A3GF 4ZH4E 3S2DF 4A3EF 1TWCF 5IYDF 1R9TF 3CQZF 3K7AF 2PPBE 2NVYF 5D4DE 5IP7F 1Y1WF 4BXXF 3S1RF 1ZYRE 2YU9F 2B63F 4MEYE 3HOUF 1I6VE 5D4CE 1TWHF 5IYBF 1SMYE 4XLNE 4OINE 5C4XF 4C3IF 1IW7E 3GTQF 5TMFE 1K83F 1I50F 5M5WF 2A69E 4A3IF 4MEXE 3GTPF 3GTMF 3HOWF 1QKLA 4BY1F 3S2HF 4C3JF 2JA5F 5M3MF 4LJZE
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5E18 E;  3HOX F;  4AYB K;  4KMU E;  2O5I E;  3S1Q F;  4KN7 E;  4Y7N F;  5TMC E;  2R92 F;  3HOY F;  3HKZ K;  2E2I F;  3GTJ F;  4A93 F;  4KN4 E;  2Y0S I;  2A6E E;  2JA6 F;  2NVQ F;  1TWG F;  3S17 F;  3H0G F;  4A3B F;  3S1M F;  1TWF F;  2PMZ K;  3DXJ E;  4MQ9 E;  4YFX E;  4C3H F;  1YNN K;  3I4M F;  4C2M F;  2R7Z F;  2A68 E;  4OIO E;  5BYH E;  3RZO F;  4GZY E;  3S16 F;  1TWA F;  4G7O E;  4JK1 E;  1HQM E;  4LK1 E;  3S15 F;  4LLG E;  4BBR F;  1Y1V F;  4Y52 F;  2O5J E;  2NVT F;  2JA8 F;  5M3F F;  5D4E E;  5C44 F;  4Q5S E;  5IYC F;  2E2H F;  3FKI F;  3GTO F;  3GTK F;  4A3J F;  1SFO F;  3EQL E;  5FJ8 F;  4A3C F;  4A3L F;  3S1N F;  3H3V G;  3M3Y F;  1YNJ K;  4LK0 E;  3WOD E;  5M5X F;  5C3E F;  5E17 E;  2BE5 E;  2JA7 F;  4BY7 F;  3PO2 F;  5FLM F;  4YFK E;  4A3K F;  3S14 F;  4OIQ E;  1I3Q F;  2WB1 I;  4A3F F;  3HOZ F;  4YFN E;  2VUM F;  2NVX F;  4YG2 E;  2CW0 E;  2WAQ K;  4X6A F;  3GTL F;  4A3D F;  3RZD F;  3I4N F;  4G7H E;  4A3M F;  4G7Z E;  5IP9 F;  1WCM F;  2A6H E;  3HOV F;  2E2J F;  1I6H F;  5M5Y F;  4OIP E;  3GTG F;  3PO3 F;  2R93 F;  3M4O F;  5IPL E;  4XLP E;  4XSZ E;  4Q4Z E;  4BBS F;  5C4J F;  4OIR E;  4XSX E;  4A3G F;  4ZH4 E;  3S2D F;  4A3E F;  1TWC F;  5IYD F;  1R9T F;  3CQZ F;  3K7A F;  2PPB E;  2NVY F;  5D4D E;  5IP7 F;  1Y1W F;  4BXX F;  3S1R F;  1ZYR E;  2YU9 F;  2B63 F;  4MEY E;  3HOU F;  1I6V E;  5D4C E;  1TWH F;  5IYB F;  1SMY E;  4XLN E;  4OIN E;  5C4X F;  4C3I F;  1IW7 E;  3GTQ F;  5TMF E;  1K83 F;  1I50 F;  5M5W F;  2A69 E;  4A3I F;  4MEX E;  3GTP F;  3GTM F;  3HOW F;  1QKL A;  4BY1 F;  3S2H F;  4C3J F;  2JA5 F;  5M3M F;  4LJZ E; 
#chains in the Genus database with same CATH topology
 3GTJ E;  5E18 E;  3HOX F;  4AYB K;  2NVQ E;  5M3M F;  1DZF A;  2JA6 E;  2O5I E;  3S1Q F;  4A93 E;  3H0G E;  4A3B E;  1TWF E;  4KN7 E;  4Y7N F;  5TMC E;  2R92 F;  3HOY F;  3HKZ K;  2E2I F;  4C3H E;  3I4M E;  2Y0S H;  3GTQ E;  3GTJ F;  2R7Z E;  4KN4 E;  2Y0S I;  2A6E E;  2JA6 F;  1I50 E;  1TWG F;  2NVQ F;  3RZO E;  3S17 F;  3H0G F;  4A3B F;  3S1M F;  1TWF F;  3S16 E;  1TWA E;  2PMZ K;  3GTP E;  3GTM E;  3HOW E;  3DXJ E;  4MQ9 E;  4YFX E;  4C3H F;  1EIK A;  1YNN K;  4QIW K;  2JA5 E;  3I4M F;  4C2M F;  5M3M E;  2R7Z F;  3HOX E;  2A68 E;  4OIO E;  5BYH E;  3RZO F;  1Y1V E;  4GZY E;  2NVT E;  3S16 F;  2JA8 E;  1TWA F;  5M3F E;  5C44 E;  4G7O E;  4JK1 E;  2R92 E;  1HQM E;  4LK1 E;  3S15 F;  4LLG E;  2E2H E;  3H3V F;  4AYB H;  3FKI E;  4BBR F;  3GTO E;  4A3J E;  1TWG E;  1Y1V F;  4Y52 F;  3S17 E;  1SFO E;  2NVT F;  2O5J E;  3S1M E;  2JA8 F;  5FJ8 E;  5M3F F;  4A3C E;  5D4E E;  5C44 F;  4A3L E;  3S1N E;  3M3Y E;  4Q5S E;  5IYC F;  5M5X E;  5C3E E;  2E2H F;  4C2M E;  3FKI F;  3GTO F;  2JA7 E;  4A3J F;  3GTK F;  3PO2 E;  5FLM E;  1SFO F;  3EQL E;  4A3K E;  3S14 E;  5FJ8 F;  4A3C F;  4A3L F;  1I3Q E;  3S1N F;  4A3F E;  3H3V G;  4QIW H;  3M3Y F;  3S15 E;  1YNJ K;  3HOZ E;  4LK0 E;  3WOD E;  5M5X F;  5C3E F;  3HOU E;  5E17 E;  2BE5 E;  4BBR E;  2JA7 F;  4BY7 F;  3PO2 F;  5FLM F;  4Y52 E;  4YFK E;  4A3K F;  2WB1 H;  3S14 F;  4X6A E;  4OIQ E;  1I3Q F;  2WB1 I;  3GTL E;  3RZD E;  4A3F F;  3I4N E;  3HOZ F;  5IP9 E;  5IYC E;  1WCM E;  4YFN E;  2VUM F;  2NVX F;  4YG2 E;  2CW0 E;  3GTK E;  2WAQ K;  3HOV E;  2E2J E;  1I6H E;  5M5Y E;  4X6A F;  2KRX A;  3HKZ H;  3GTL F;  4A3D F;  3RZD F;  3GTG E;  3I4N F;  4G7H E;  3PO3 E;  4A3M F;  4G7Z E;  5IP9 F;  1WCM F;  4BBS E;  5C4J E;  2A6H E;  4BY7 E;  4A3G E;  3HOV F;  2E2J F;  2PMZ H;  1I6H F;  5M5Y F;  4OIP E;  4A3E E;  1TWC E;  5IYD E;  1R9T E;  3CQZ E;  3GTG F;  3PO3 F;  2R93 F;  3M4O F;  3K7A E;  4XLP E;  5IPL E;  2NVY E;  4XSZ E;  2VUM E;  4Q4Z E;  2NVX E;  5C4J F;  1Y1W E;  4BBS F;  4BXX E;  4OIR E;  4XSX E;  4A3G F;  4ZH4 E;  2YU9 E;  2B63 E;  3S2D F;  4A3E F;  4A3D E;  1TWC F;  5IYD F;  1R9T F;  3CQZ F;  1TWH E;  3K7A F;  5IYB E;  4A3M E;  2PPB E;  2NVY F;  5D4D E;  2WAQ H;  5IP7 F;  1Y1W F;  4BXX F;  3S1R F;  1ZYR E;  5C4X E;  2YU9 F;  4C3I E;  4MEY E;  2B63 F;  3HOU F;  1K83 E;  1I6V E;  5M5W E;  2R93 E;  5D4C E;  4A3I E;  1TWH F;  5IYB F;  3M4O E;  4A93 F;  4BY1 E;  1SMY E;  4XLN E;  3S1R E;  3S2H E;  4OIN E;  4C3J E;  5C4X F;  4C3I F;  1IW7 E;  3GTQ F;  5TMF E;  3S2D E;  1K83 F;  1I50 F;  3S1Q E;  5M5W F;  2A69 E;  4A3I F;  4MEX E;  4Y7N E;  3GTP F;  3GTM F;  3HOY E;  3HOW F;  1QKL A;  4BY1 F;  5IP7 E;  2E2I E;  3S2H F;  4C3J F;  2JA5 F;  4KMU E;  4LJZ E; 
#chains in the Genus database with same CATH homology
 5E18 E;  3HOX F;  4AYB K;  4KMU E;  2O5I E;  3S1Q F;  4KN7 E;  4Y7N F;  5TMC E;  2R92 F;  3HOY F;  3HKZ K;  2E2I F;  3GTJ F;  4A93 F;  4KN4 E;  2Y0S I;  2A6E E;  2JA6 F;  2NVQ F;  1TWG F;  3S17 F;  3H0G F;  4A3B F;  3S1M F;  1TWF F;  2PMZ K;  3DXJ E;  4MQ9 E;  4YFX E;  4C3H F;  1YNN K;  4QIW K;  3I4M F;  4C2M F;  2R7Z F;  2A68 E;  4OIO E;  5BYH E;  3RZO F;  4GZY E;  3S16 F;  1TWA F;  4G7O E;  4JK1 E;  1HQM E;  4LK1 E;  3S15 F;  4LLG E;  4BBR F;  1Y1V F;  4Y52 F;  2O5J E;  2NVT F;  2JA8 F;  5M3F F;  5D4E E;  5C44 F;  4Q5S E;  5IYC F;  2E2H F;  3FKI F;  3GTO F;  3GTK F;  4A3J F;  1SFO F;  3EQL E;  5FJ8 F;  4A3C F;  4A3L F;  3S1N F;  3H3V G;  3M3Y F;  1YNJ K;  4LK0 E;  3WOD E;  5M5X F;  5C3E F;  5E17 E;  2BE5 E;  2JA7 F;  4BY7 F;  3PO2 F;  5FLM F;  4YFK E;  4A3K F;  3S14 F;  4OIQ E;  1I3Q F;  2WB1 I;  4A3F F;  3HOZ F;  4YFN E;  2VUM F;  2NVX F;  4YG2 E;  2CW0 E;  2WAQ K;  4X6A F;  2KRX A;  3GTL F;  4A3D F;  3RZD F;  3I4N F;  4G7H E;  4A3M F;  4G7Z E;  5IP9 F;  1WCM F;  2A6H E;  3HOV F;  2E2J F;  1I6H F;  5M5Y F;  4OIP E;  3GTG F;  3PO3 F;  2R93 F;  3M4O F;  5IPL E;  4XLP E;  4XSZ E;  4Q4Z E;  4BBS F;  5C4J F;  4OIR E;  4XSX E;  4A3G F;  4ZH4 E;  3S2D F;  4A3E F;  1TWC F;  5IYD F;  1R9T F;  3CQZ F;  3K7A F;  2PPB E;  2NVY F;  5D4D E;  5IP7 F;  1Y1W F;  4BXX F;  3S1R F;  1ZYR E;  2YU9 F;  2B63 F;  4MEY E;  3HOU F;  1I6V E;  5D4C E;  1TWH F;  5IYB F;  1SMY E;  4XLN E;  4OIN E;  5C4X F;  4C3I F;  1IW7 E;  3GTQ F;  5TMF E;  1K83 F;  1I50 F;  5M5W F;  2A69 E;  4A3I F;  4MEX E;  3GTP F;  3GTM F;  3HOW F;  1QKL A;  4BY1 F;  3S2H F;  4C3J F;  2JA5 F;  5M3M F;  4LJZ E; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...